Protegrin-1 inhibits dengue NS2B-NS3 serine protease and viral replication in MK2 cells

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Rothan, Hussin A ^a   Abdulrahman, Ammar Y ^a   Sasikumer, Pottayil G ^b   Othman, Shatrah ^a   Abd Rahman, Noorsaadah ^a   Yusof, Rohana ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b Aurigene Discovery Technologies Limited   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; PROTEGRIN; RECOMBINANT PROTEGRIN 1; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; ENZYME INHIBITOR; NS2B PROTEIN, FLAVIVIRUS; NS3 PROTEASE, DENGUE VIRUS; PROTEGRIN 1; PROTEGRIN-1; SERINE PROTEINASE; VIRUS PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CELL STRAIN; DENGUE VIRUS 2; DISULFIDE BOND; DRUG PURIFICATION; DRUG SYNTHESIS; ESCHERICHIA COLI; FLUORESCENCE ANALYSIS; IC 50; LIQUID CHROMATOGRAPHY; NONHUMAN; REACTION TIME; REAL TIME POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RHESUS MONKEY; SOLID PHASE SYNTHESIS; VIRUS INHIBITION; VIRUS REPLICATION; ANIMAL; CELL LINE; DENGUE VIRUS; DRUG EFFECT; ENZYMOLOGY; KIDNEY; METABOLISM; PHYSIOLOGY; VIROLOGY;

DENGUE VIRUS; MACACA MULATTA;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL LINE; DENGUE VIRUS; ENZYME INHIBITORS; KIDNEY; MACACA MULATTA; SERINE ENDOPEPTIDASES; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84871836593     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/251482     Document Type: Article

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