메뉴 건너뛰기




Volumn 94, Issue 1, 2012, Pages 72-79

Retro peptide-hybrids as selective inhibitors of the Dengue virus NS2B-NS3 protease

Author keywords

Dengue virus; Hybrid retro peptides; NS2B NS3 protease; Thrombin; West Nile virus

Indexed keywords

ANTIVIRUS AGENT; APROTININ; DIPEPTIDE DERIVATIVE; HYBRID PROTEIN; NS2B NS3 PROTEASE; PROTEINASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 84858145412     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2012.02.008     Document Type: Article
Times cited : (84)

References (20)
  • 3
    • 0028875452 scopus 로고
    • Recent developments in retro peptides and proteins - an ongoing topochemical exploration
    • Chorev M., Goodman M. Recent developments in retro peptides and proteins - an ongoing topochemical exploration. Trends Biotechnol. 1995, 13:438-445.
    • (1995) Trends Biotechnol. , vol.13 , pp. 438-445
    • Chorev, M.1    Goodman, M.2
  • 4
    • 84859874998 scopus 로고    scopus 로고
    • Thrombin 1536 HTS, PubChem Bio-Assay ID 1046. Available from: (12.10.11)
    • Diamond, S.L., 2011. Thrombin 1536 HTS, PubChem Bio-Assay ID 1046. Available from: (12.10.11). http://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=1046&loc=ea_ras.
    • (2011)
    • Diamond, S.L.1
  • 7
    • 53249121029 scopus 로고    scopus 로고
    • Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target
    • Lescar J., Luo D., Xu T., Sampath A., Lim S.P., Canard B., Vasudevan S.G. Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target. Antiviral Res. 2008, 80:94-101.
    • (2008) Antiviral Res. , vol.80 , pp. 94-101
    • Lescar, J.1    Luo, D.2    Xu, T.3    Sampath, A.4    Lim, S.P.5    Canard, B.6    Vasudevan, S.G.7
  • 9
    • 82255192015 scopus 로고    scopus 로고
    • Arylcyanoacrylamides as inhibitors of the Dengue and West Nile virus proteases
    • Nitsche C., Steuer C., Klein C.D. Arylcyanoacrylamides as inhibitors of the Dengue and West Nile virus proteases. Bioorg. Med. Chem. 2011, 19:7318-7337.
    • (2011) Bioorg. Med. Chem. , vol.19 , pp. 7318-7337
    • Nitsche, C.1    Steuer, C.2    Klein, C.D.3
  • 10
    • 84855921187 scopus 로고    scopus 로고
    • Ligand-bound structures of the dengue virus protease reveal the active conformation
    • Noble C.G., She C.C., Chao A.T., Shi P.Y. Ligand-bound structures of the dengue virus protease reveal the active conformation. J. Virol. 2012, 86:438-446.
    • (2012) J. Virol. , vol.86 , pp. 438-446
    • Noble, C.G.1    She, C.C.2    Chao, A.T.3    Shi, P.Y.4
  • 12
  • 14
    • 74049147097 scopus 로고    scopus 로고
    • Optimization of assay conditions for dengue virus protease: effect of various polyols and nonionic detergents
    • Steuer C., Heinonen K.H., Kattner L., Klein C.D. Optimization of assay conditions for dengue virus protease: effect of various polyols and nonionic detergents. J. Biomol. Screen. 2009, 14:1102-1108.
    • (2009) J. Biomol. Screen. , vol.14 , pp. 1102-1108
    • Steuer, C.1    Heinonen, K.H.2    Kattner, L.3    Klein, C.D.4
  • 15
    • 79959530775 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of alpha-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture
    • Steuer C., Gege C., Fischl W., Heinonen K.H., Bartenschlager R., Klein C.D. Synthesis and biological evaluation of alpha-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture. Bioorg. Med. Chem. 2011, 19:4067-4074.
    • (2011) Bioorg. Med. Chem. , vol.19 , pp. 4067-4074
    • Steuer, C.1    Gege, C.2    Fischl, W.3    Heinonen, K.H.4    Bartenschlager, R.5    Klein, C.D.6
  • 19
    • 0034616194 scopus 로고    scopus 로고
    • Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro
    • Yusof R., Clum S., Wetzel M., Murthy H.M., Padmanabhan R. Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro. J. Biol. Chem. 2000, 275:9963-9969.
    • (2000) J. Biol. Chem. , vol.275 , pp. 9963-9969
    • Yusof, R.1    Clum, S.2    Wetzel, M.3    Murthy, H.M.4    Padmanabhan, R.5
  • 20
    • 0036120055 scopus 로고    scopus 로고
    • Palladium-catalysed arylation of butyl acrylate and acrylamide with aryl iodides in water
    • Zhao H., Cai M.Z., Peng C.Y., Song C.S. Palladium-catalysed arylation of butyl acrylate and acrylamide with aryl iodides in water. J. Chem. Res 2002, 28-29.
    • (2002) J. Chem. Res , pp. 28-29
    • Zhao, H.1    Cai, M.Z.2    Peng, C.Y.3    Song, C.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.