Allosteric inhibition of the NS2B-NS3 protease from dengue virus

ACS Chemical Biology

Volumn 8, Issue 12, 2013, Pages 2744-2752

  Yildiz, Muslum ^a   Ghosh, Sumana ^a,c   Bell, Jeffrey A ^b   Sherman, Woody ^b   Hardy, Jeanne A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b SCHRÖDINGER INC   (United States)

^c Patparganj Industrial Area   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYSTEINE; DENGUE VIRUS PROTEASE NS2B-NS3PRO; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DENGUE VIRUS; ENZYME ACTIVE SITE; MOLECULAR WEIGHT; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANTIVIRAL AGENTS; CATALYTIC DOMAIN; CYSTEINE; DENGUE VIRUS; ENZYME ACTIVATION; KINETICS; MOLECULAR DOCKING SIMULATION; MOLECULAR PROBES; MUTATION; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84890813052     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400612h     Document Type: Article

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