SCOPUS 정보 검색 플랫폼

Volumn 19, Issue 13, 2011, Pages 4067-4074

Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture

(6) Steuer, Christian a Gege, Christian a Fischl, Wolfgang a Heinonen, Karl H a Bartenschlager, Ralf a Klein, Christian D a

a UNIVERSITY OF HEIDELBERG (Germany)

Author keywords

Dengue virus; Flavivirus; Ketoamides; NS2B NS3 protease; Protease inhibitors

Indexed keywords

ALPHA KETOAMIDE DERIVATIVE; AMIDE; N (TERT BUTYL) 2 OXO 4 (3,4,5 TRIMETHOXYPHENYL)BUT 3 ENAMIDE; N (TERT BUTYL) 2 OXO 4 (PYRIDIN 3 YL)BUT 3 ENAMIDE; N (TERT BUTYL) 4 (4 CHLOROPHENYL) 2 OXO BUT 3 ENAMIDE; PROTEINASE; SERINE; SERINE PROTEINASE INHIBITOR; THROMBIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CELL CULTURE; CONTROLLED STUDY; DENGUE VIRUS; DRUG DETERMINATION; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ELECTROPHILICITY; ENZYME INHIBITION; FLAVIVIRUS; HUMAN; HUMAN CELL; MOLECULAR MODEL; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION; VIRUS REPLICATION; WEST NILE FLAVIVIRUS;

AMIDES; ANTIVIRAL AGENTS; BINDING SITES; COMPUTER SIMULATION; DENGUE VIRUS; HUMANS; PEPTIDE HYDROLASES; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS; VIRUS REPLICATION; WEST NILE VIRUS;

DENGUE VIRUS; FLAVIVIRUS; WEST NILE VIRUS;

EID: 79959530775 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.05.015 Document Type: Article

Times cited : (128)

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