-
1
-
-
31044432090
-
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
-
Ahnesorg P., Smith P., Jackson S.P. XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. Cell 2006, 124:301-313.
-
(2006)
Cell
, vol.124
, pp. 301-313
-
-
Ahnesorg, P.1
Smith, P.2
Jackson, S.P.3
-
2
-
-
67651156039
-
Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases lambda and mu for nonhomologous end joining in human whole-cell extracts
-
Akopiants K., Zhou R.-Z., Mohapatra S., Valerie K., Lees-Miller S.P., Lee K.-J., Chen D.J., Revy P., de Villartay J.-P., Povirk L.F. Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases lambda and mu for nonhomologous end joining in human whole-cell extracts. Nucleic Acids Res. 2009, 37:4055-4062.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 4055-4062
-
-
Akopiants, K.1
Zhou, R.-Z.2
Mohapatra, S.3
Valerie, K.4
Lees-Miller, S.P.5
Lee, K.-J.6
Chen, D.J.7
Revy, P.8
de Villartay, J.-P.9
Povirk, L.F.10
-
3
-
-
2442706035
-
H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity
-
Bassing C.H., Alt F.W. H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity. Cell Cycle 2004, 3:149-153.
-
(2004)
Cell Cycle
, vol.3
, pp. 149-153
-
-
Bassing, C.H.1
Alt, F.W.2
-
4
-
-
0032971199
-
Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4
-
Bryans M., Valenzano M.C., Stamato T.D. Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4. Mutat. Res. 1999, 433:53-58.
-
(1999)
Mutat. Res.
, vol.433
, pp. 53-58
-
-
Bryans, M.1
Valenzano, M.C.2
Stamato, T.D.3
-
5
-
-
31044440630
-
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
-
Buck D., Malivert L., de Chasseval R., Barraud A., Fondanèche M.-C., Sanal O., Plebani A., Stéphan J.-L., Hufnagel M., le Deist F., et al. Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly. Cell 2006, 124:287-299.
-
(2006)
Cell
, vol.124
, pp. 287-299
-
-
Buck, D.1
Malivert, L.2
de Chasseval, R.3
Barraud, A.4
Fondanèche, M.-C.5
Sanal, O.6
Plebani, A.7
Stéphan, J.-L.8
Hufnagel, M.9
le Deist, F.10
-
6
-
-
0033583204
-
The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA
-
Calsou P., Frit P., Humbert O., Muller C., Chen D.J., Salles B. The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA. J. Biol. Chem. 1999, 274:7848-7856.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7848-7856
-
-
Calsou, P.1
Frit, P.2
Humbert, O.3
Muller, C.4
Chen, D.J.5
Salles, B.6
-
7
-
-
0025201179
-
A DNA-activated protein kinase from HeLa cell nuclei
-
Carter T., Vancurová I., Sun I., Lou W., DeLeon S. A DNA-activated protein kinase from HeLa cell nuclei. Mol. Cell. Biol. 1990, 10:6460-6471.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 6460-6471
-
-
Carter, T.1
Vancurová, I.2
Sun, I.3
Lou, W.4
DeLeon, S.5
-
8
-
-
0030903145
-
DNA looping by Ku and the DNA-dependent protein kinase
-
Cary R.B., Peterson S.R., Wang J., Bear D.G., Bradbury E.M., Chen D.J. DNA looping by Ku and the DNA-dependent protein kinase. Proc. Natl. Acad. Sci. U S A 1997, 94:4267-4272.
-
(1997)
Proc. Natl. Acad. Sci. U S A
, vol.94
, pp. 4267-4272
-
-
Cary, R.B.1
Peterson, S.R.2
Wang, J.3
Bear, D.G.4
Bradbury, E.M.5
Chen, D.J.6
-
10
-
-
84873049469
-
A noncatalytic function of the ligation complex during nonhomologous end joining
-
Cottarel J., Frit P., Bombarde O., Salles B., Négrel A., Bernard S., Jeggo P.A., Lieber M.R., Modesti M., Calsou P. A noncatalytic function of the ligation complex during nonhomologous end joining. J. Cell Biol. 2013, 200:173-186.
-
(2013)
J. Cell Biol.
, vol.200
, pp. 173-186
-
-
Cottarel, J.1
Frit, P.2
Bombarde, O.3
Salles, B.4
Négrel, A.5
Bernard, S.6
Jeggo, P.A.7
Lieber, M.R.8
Modesti, M.9
Calsou, P.10
-
11
-
-
84939946728
-
XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair
-
Craxton A., Somers J., Munnur D., Jukes-Jones R., Cain K., Malewicz M. XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair. Cell Death Differ. 2015, 22:890-897.
-
(2015)
Cell Death Differ.
, vol.22
, pp. 890-897
-
-
Craxton, A.1
Somers, J.2
Munnur, D.3
Jukes-Jones, R.4
Cain, K.5
Malewicz, M.6
-
12
-
-
0031214080
-
Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
-
Critchlow S.E., Bowater R.P., Jackson S.P. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr. Biol. 1997, 7:588-598.
-
(1997)
Curr. Biol.
, vol.7
, pp. 588-598
-
-
Critchlow, S.E.1
Bowater, R.P.2
Jackson, S.P.3
-
13
-
-
0037124373
-
Synapsis of DNA ends by DNA-dependent protein kinase
-
DeFazio L.G., Stansel R.M., Griffith J.D., Chu G. Synapsis of DNA ends by DNA-dependent protein kinase. EMBO J. 2002, 21:3192-3200.
-
(2002)
EMBO J.
, vol.21
, pp. 3192-3200
-
-
DeFazio, L.G.1
Stansel, R.M.2
Griffith, J.D.3
Chu, G.4
-
14
-
-
28544436537
-
Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11
-
Di Virgilio M., Gautier J. Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11. J. Cell Biol. 2005, 171:765-771.
-
(2005)
J. Cell Biol.
, vol.171
, pp. 765-771
-
-
Di Virgilio, M.1
Gautier, J.2
-
15
-
-
0043133778
-
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
-
Ding Q., Reddy Y.V.R., Wang W., Woods T., Douglas P., Ramsden D.A., Lees-Miller S.P., Meek K. Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Mol. Cell. Biol. 2003, 23:5836-5848.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5836-5848
-
-
Ding, Q.1
Reddy, Y.V.R.2
Wang, W.3
Woods, T.4
Douglas, P.5
Ramsden, D.A.6
Lees-Miller, S.P.7
Meek, K.8
-
16
-
-
78649446475
-
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation
-
Dobbs T.A., Tainer J.A., Lees-Miller S.P. A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation. DNA Repair (Amst.) 2010, 9:1307-1314.
-
(2010)
DNA Repair (Amst.)
, vol.9
, pp. 1307-1314
-
-
Dobbs, T.A.1
Tainer, J.A.2
Lees-Miller, S.P.3
-
17
-
-
0027048773
-
Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II
-
Dvir A., Peterson S.R., Knuth M.W., Lu H., Dynan W.S. Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. Proc. Natl. Acad. Sci. U S A 1992, 89:11920-11924.
-
(1992)
Proc. Natl. Acad. Sci. U S A
, vol.89
, pp. 11920-11924
-
-
Dvir, A.1
Peterson, S.R.2
Knuth, M.W.3
Lu, H.4
Dynan, W.S.5
-
18
-
-
0027246193
-
Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II
-
Dvir A., Stein L.Y., Calore B.L., Dynan W.S. Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II. J. Biol. Chem. 1993, 268:10440-10447.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10440-10447
-
-
Dvir, A.1
Stein, L.Y.2
Calore, B.L.3
Dynan, W.S.4
-
19
-
-
0027397867
-
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
-
Gottlieb T.M., Jackson S.P. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 1993, 72:131-142.
-
(1993)
Cell
, vol.72
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
20
-
-
0030743386
-
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
-
Grawunder U., Wilm M., Wu X., Kulesza P., Wilson T.E., Mann M., Lieber M.R. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 1997, 388:492-495.
-
(1997)
Nature
, vol.388
, pp. 492-495
-
-
Grawunder, U.1
Wilm, M.2
Wu, X.3
Kulesza, P.4
Wilson, T.E.5
Mann, M.6
Lieber, M.R.7
-
21
-
-
34848841930
-
Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence
-
Gu J., Lu H., Tsai A.G., Schwarz K., Lieber M.R. Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence. Nucleic Acids Res. 2007, 35:5755-5762.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 5755-5762
-
-
Gu, J.1
Lu, H.2
Tsai, A.G.3
Schwarz, K.4
Lieber, M.R.5
-
22
-
-
74049134920
-
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex
-
Hammel M., Yu Y., Mahaney B.L., Cai B., Ye R., Phipps B.M., Rambo R.P., Hura G.L., Pelikan M., So S., et al. Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J. Biol. Chem. 2010, 285:1414-1423.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1414-1423
-
-
Hammel, M.1
Yu, Y.2
Mahaney, B.L.3
Cai, B.4
Ye, R.5
Phipps, B.M.6
Rambo, R.P.7
Hura, G.L.8
Pelikan, M.9
So, S.10
-
23
-
-
62549130381
-
Live cell microscopy analysis of radiation-induced DNA double-strand break motion
-
Jakob B., Splinter J., Durante M., Taucher-Scholz G. Live cell microscopy analysis of radiation-induced DNA double-strand break motion. Proc. Natl. Acad. Sci. U S A 2009, 106:3172-3177.
-
(2009)
Proc. Natl. Acad. Sci. U S A
, vol.106
, pp. 3172-3177
-
-
Jakob, B.1
Splinter, J.2
Durante, M.3
Taucher-Scholz, G.4
-
24
-
-
84938982424
-
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis
-
Jette N., Lees-Miller S.P. The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis. Prog. Biophys. Mol. Biol. 2015, 117:194-205.
-
(2015)
Prog. Biophys. Mol. Biol.
, vol.117
, pp. 194-205
-
-
Jette, N.1
Lees-Miller, S.P.2
-
25
-
-
84926154210
-
Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining
-
Jiang W., Crowe J.L., Liu X., Nakajima S., Wang Y., Li C., Lee B.J., Dubois R.L., Liu C., Yu X., et al. Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining. Mol. Cell 2015, 58:172-185.
-
(2015)
Mol. Cell
, vol.58
, pp. 172-185
-
-
Jiang, W.1
Crowe, J.L.2
Liu, X.3
Nakajima, S.4
Wang, Y.5
Li, C.6
Lee, B.J.7
Dubois, R.L.8
Liu, C.9
Yu, X.10
-
26
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak M.J., Celeste A., Dellaire G., Fernandez-Capetillo O., Müller W.G., McNally J.G., Bazett-Jones D.P., Nussenzweig A. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 2006, 172:823-834.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 823-834
-
-
Kruhlak, M.J.1
Celeste, A.2
Dellaire, G.3
Fernandez-Capetillo, O.4
Müller, W.G.5
McNally, J.G.6
Bazett-Jones, D.P.7
Nussenzweig, A.8
-
27
-
-
0032934980
-
Ku-dependent nonhomologous DNA end joining in Xenopus egg extracts
-
Labhart P. Ku-dependent nonhomologous DNA end joining in Xenopus egg extracts. Mol. Cell. Biol. 1999, 19:2585-2593.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2585-2593
-
-
Labhart, P.1
-
28
-
-
0017617464
-
Assembly of SV40 chromatin in a cell-free system from Xenopus eggs
-
Laskey R.A., Mills A.D., Morris N.R. Assembly of SV40 chromatin in a cell-free system from Xenopus eggs. Cell 1977, 10:237-243.
-
(1977)
Cell
, vol.10
, pp. 237-243
-
-
Laskey, R.A.1
Mills, A.D.2
Morris, N.R.3
-
30
-
-
79551501163
-
DNA is a co-factor for its own replication in Xenopus egg extracts
-
Lebofsky R., van Oijen A.M., Walter J.C. DNA is a co-factor for its own replication in Xenopus egg extracts. Nucleic Acids Res. 2011, 39:545-555.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 545-555
-
-
Lebofsky, R.1
van Oijen, A.M.2
Walter, J.C.3
-
31
-
-
0037224429
-
Requirement for XRCC4 and DNA ligase IV in alignment-based gap filling for nonhomologous DNA end joining in vitro
-
Lee J.W., Yannone S.M., Chen D.J., Povirk L.F. Requirement for XRCC4 and DNA ligase IV in alignment-based gap filling for nonhomologous DNA end joining in vitro. Cancer Res. 2003, 63:22-24.
-
(2003)
Cancer Res.
, vol.63
, pp. 22-24
-
-
Lee, J.W.1
Yannone, S.M.2
Chen, D.J.3
Povirk, L.F.4
-
32
-
-
0025224761
-
Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen
-
Lees-Miller S.P., Chen Y.R., Anderson C.W. Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol. Cell. Biol. 1990, 10:6472-6481.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 6472-6481
-
-
Lees-Miller, S.P.1
Chen, Y.R.2
Anderson, C.W.3
-
33
-
-
0028937877
-
Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line
-
Lees-Miller S.P., Godbout R., Chan D.W., Weinfeld M., Day R.S., Barron G.M., Allalunis-Turner J. Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science 1995, 267:1183-1185.
-
(1995)
Science
, vol.267
, pp. 1183-1185
-
-
Lees-Miller, S.P.1
Godbout, R.2
Chan, D.W.3
Weinfeld, M.4
Day, R.S.5
Barron, G.M.6
Allalunis-Turner, J.7
-
34
-
-
34249685474
-
Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity
-
Lu H., Pannicke U., Schwarz K., Lieber M.R. Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity. J. Biol. Chem. 2007, 282:11155-11162.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11155-11162
-
-
Lu, H.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
35
-
-
84904567038
-
3D trajectories adopted by coding and regulatory DNA elements: first-passage times for genomic interactions
-
Lucas J.S., Zhang Y., Dudko O.K., Murre C. 3D trajectories adopted by coding and regulatory DNA elements: first-passage times for genomic interactions. Cell 2014, 158:339-352.
-
(2014)
Cell
, vol.158
, pp. 339-352
-
-
Lucas, J.S.1
Zhang, Y.2
Dudko, O.K.3
Murre, C.4
-
36
-
-
25444475799
-
Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model
-
Ma Y., Lu H., Schwarz K., Lieber M.R. Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model. Cell Cycle 2005, 4:1193-1200.
-
(2005)
Cell Cycle
, vol.4
, pp. 1193-1200
-
-
Ma, Y.1
Lu, H.2
Schwarz, K.3
Lieber, M.R.4
-
37
-
-
84874878472
-
XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair
-
Mahaney B.L., Hammel M., Meek K., Tainer J.A., Lees-Miller S.P. XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair. Biochem. Cell Biol. 2013, 91:31-41.
-
(2013)
Biochem. Cell Biol.
, vol.91
, pp. 31-41
-
-
Mahaney, B.L.1
Hammel, M.2
Meek, K.3
Tainer, J.A.4
Lees-Miller, S.P.5
-
38
-
-
84922384279
-
DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
-
Ochi T., Blackford A.N., Coates J., Jhujh S., Mehmood S., Tamura N., Travers J., Wu Q., Draviam V.M., Robinson C.V., et al. DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science 2015, 347:185-188.
-
(2015)
Science
, vol.347
, pp. 185-188
-
-
Ochi, T.1
Blackford, A.N.2
Coates, J.3
Jhujh, S.4
Mehmood, S.5
Tamura, N.6
Travers, J.7
Wu, Q.8
Draviam, V.M.9
Robinson, C.V.10
-
39
-
-
0028902932
-
Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
-
Peterson S.R., Kurimasa A., Oshimura M., Dynan W.S., Bradbury E.M., Chen D.J. Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. U S A 1995, 92:3171-3174.
-
(1995)
Proc. Natl. Acad. Sci. U S A
, vol.92
, pp. 3171-3174
-
-
Peterson, S.R.1
Kurimasa, A.2
Oshimura, M.3
Dynan, W.S.4
Bradbury, E.M.5
Chen, D.J.6
-
40
-
-
49749093073
-
Ku80 removal from DNA through double strand break-induced ubiquitylation
-
Postow L., Ghenoiu C., Woo E.M., Krutchinsky A.N., Chait B.T., Funabiki H. Ku80 removal from DNA through double strand break-induced ubiquitylation. J. Cell Biol. 2008, 182:467-479.
-
(2008)
J. Cell Biol.
, vol.182
, pp. 467-479
-
-
Postow, L.1
Ghenoiu, C.2
Woo, E.M.3
Krutchinsky, A.N.4
Chait, B.T.5
Funabiki, H.6
-
42
-
-
0032518680
-
Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks
-
Ramsden D.A., Gellert M. Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks. EMBO J. 1998, 17:609-614.
-
(1998)
EMBO J.
, vol.17
, pp. 609-614
-
-
Ramsden, D.A.1
Gellert, M.2
-
43
-
-
84929465548
-
Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair
-
Reid D.A., Keegan S., Leo-Macias A., Watanabe G., Strande N.T., Chang H.H., Oksuz B.A., Fenyo D., Lieber M.R., Ramsden D.A., Rothenberg E. Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair. Proc. Natl. Acad. Sci. U S A 2015, 112:E2575-E2584.
-
(2015)
Proc. Natl. Acad. Sci. U S A
, vol.112
, pp. E2575-E2584
-
-
Reid, D.A.1
Keegan, S.2
Leo-Macias, A.3
Watanabe, G.4
Strande, N.T.5
Chang, H.H.6
Oksuz, B.A.7
Fenyo, D.8
Lieber, M.R.9
Ramsden, D.A.10
Rothenberg, E.11
-
44
-
-
84938882573
-
XRCC4/XLF interaction is variably required for DNA repair, and is not required for Ligase IV stimulation
-
Roy S., de Melo A.J., Xu Y., Tadi S.K., Négrel A., Hendrickson E., Modesti M., Meek K. XRCC4/XLF interaction is variably required for DNA repair, and is not required for Ligase IV stimulation. Mol. Cell. Biol. 2015, 35:3017-3028.
-
(2015)
Mol. Cell. Biol.
, vol.35
, pp. 3017-3028
-
-
Roy, S.1
de Melo, A.J.2
Xu, Y.3
Tadi, S.K.4
Négrel, A.5
Hendrickson, E.6
Modesti, M.7
Meek, K.8
-
45
-
-
73849140503
-
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats
-
Sibanda B.L., Chirgadze D.Y., Blundell T.L. Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats. Nature 2010, 463:118-121.
-
(2010)
Nature
, vol.463
, pp. 118-121
-
-
Sibanda, B.L.1
Chirgadze, D.Y.2
Blundell, T.L.3
-
46
-
-
34447574977
-
Positional stability of single double-strand breaks in mammalian cells
-
Soutoglou E., Dorn J.F., Sengupta K., Jasin M., Nussenzweig A., Ried T., Danuser G., Misteli T. Positional stability of single double-strand breaks in mammalian cells. Nat. Cell Biol. 2007, 9:675-682.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 675-682
-
-
Soutoglou, E.1
Dorn, J.F.2
Sengupta, K.3
Jasin, M.4
Nussenzweig, A.5
Ried, T.6
Danuser, G.7
Misteli, T.8
-
47
-
-
33646714595
-
Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair
-
Spagnolo L., Rivera-Calzada A., Pearl L.H., Llorca O. Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair. Mol. Cell 2006, 22:511-519.
-
(2006)
Mol. Cell
, vol.22
, pp. 511-519
-
-
Spagnolo, L.1
Rivera-Calzada, A.2
Pearl, L.H.3
Llorca, O.4
-
48
-
-
0025274315
-
A novel pathway of DNA end-to-end joining
-
Thode S., Schäfer A., Pfeiffer P., Vielmetter W. A novel pathway of DNA end-to-end joining. Cell 1990, 60:921-928.
-
(1990)
Cell
, vol.60
, pp. 921-928
-
-
Thode, S.1
Schäfer, A.2
Pfeiffer, P.3
Vielmetter, W.4
-
49
-
-
34249938518
-
Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends
-
Tsai C.J., Kim S.A., Chu G. Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proc. Natl. Acad. Sci. U S A 2007, 104:7851-7856.
-
(2007)
Proc. Natl. Acad. Sci. U S A
, vol.104
, pp. 7851-7856
-
-
Tsai, C.J.1
Kim, S.A.2
Chu, G.3
-
50
-
-
84900408873
-
Nonhomologous end joining: a good solution for bad ends
-
Waters C.A., Strande N.T., Wyatt D.W., Pryor J.M., Ramsden D.A. Nonhomologous end joining: a good solution for bad ends. DNA Repair (Amst.) 2014, 17:39-51.
-
(2014)
DNA Repair (Amst.)
, vol.17
, pp. 39-51
-
-
Waters, C.A.1
Strande, N.T.2
Wyatt, D.W.3
Pryor, J.M.4
Ramsden, D.A.5
-
51
-
-
84903971427
-
The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining
-
Waters C.A., Strande N.T., Pryor J.M., Strom C.N., Mieczkowski P., Burkhalter M.D., Oh S., Qaqish B.F., Moore D.T., Hendrickson E.A., Ramsden D.A. The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining. Nat. Commun. 2014, 5:4286.
-
(2014)
Nat. Commun.
, vol.5
, pp. 4286
-
-
Waters, C.A.1
Strande, N.T.2
Pryor, J.M.3
Strom, C.N.4
Mieczkowski, P.5
Burkhalter, M.D.6
Oh, S.7
Qaqish, B.F.8
Moore, D.T.9
Hendrickson, E.A.10
Ramsden, D.A.11
-
52
-
-
0348149145
-
The role of DNA dependent protein kinase in synapsis of DNA ends
-
Weterings E., Verkaik N.S., Brüggenwirth H.T., Hoeijmakers J.H.J., van Gent D.C. The role of DNA dependent protein kinase in synapsis of DNA ends. Nucleic Acids Res. 2003, 31:7238-7246.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 7238-7246
-
-
Weterings, E.1
Verkaik, N.S.2
Brüggenwirth, H.T.3
Hoeijmakers, J.H.J.4
van Gent, D.C.5
-
53
-
-
84923107266
-
Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway
-
Xing M., Yang M., Huo W., Feng F., Wei L., Jiang W., Ning S., Yan Z., Li W., Wang Q., et al. Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat. Commun. 2015, 6:6233.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6233
-
-
Xing, M.1
Yang, M.2
Huo, W.3
Feng, F.4
Wei, L.5
Jiang, W.6
Ning, S.7
Yan, Z.8
Li, W.9
Wang, Q.10
-
54
-
-
34248400443
-
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells
-
Zha S., Alt F.W., Cheng H.-L., Brush J.W., Li G. Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells. Proc. Natl. Acad. Sci. U S A 2007, 104:4518-4523.
-
(2007)
Proc. Natl. Acad. Sci. U S A
, vol.104
, pp. 4518-4523
-
-
Zha, S.1
Alt, F.W.2
Cheng, H.-L.3
Brush, J.W.4
Li, G.5
|