Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 20, 2015, Pages E2575-E2584

  Reid, Dylan A ^a   Keegan, Sarah ^a   Leo Macias, Alejandra ^a   Watanabe, Go ^b   Strande, Natasha T ^c   Chang, Howard H ^b   Oksuz, Betul Akgol ^a   Fenyo, David ^a   Lieber, Michael R ^b   Ramsden, Dale A ^c   Rothenberg, Eli ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

DNA repair; Genomic integrity; Nonhomologous end joining; Single molecule FRET; Super resolution microscopy

Indexed keywords

XRCC4 PROTEIN; ATP DEPENDENT DNA LIGASE; DNA BINDING PROTEIN; DNA LIGASE; LIG4 PROTEIN, HUMAN; XRCC4 PROTEIN, HUMAN;

ARTICLE; BUTTERFLY; CATERPILLAR; CHROMATIN STRUCTURE; CHROMOSOME PAIRING; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; SYNAPSE; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT ANTIBODY TECHNIQUE; KINETICS; METABOLISM; MOLECULAR MODEL; PHYSIOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

SYNAPSIS;

BLOTTING, WESTERN; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA LIGASE ATP; DNA LIGASES; DNA-BINDING PROTEINS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; KINETICS; MODELS, MOLECULAR;

EID: 84929465548     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420115112     Document Type: Article

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