Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

Nature Communications

Volumn 6, Issue , 2015, Pages

  Xing, Mengtan ^a   Yang, Mingrui ^b,c   Huo, Wei ^a   Feng, Feng ^b   Wei, Leizhen ^d   Jiang, Wenxia ^e   Ning, Shaokai ^a   Yan, Zhenxin ^a   Li, Wen ^a   Wang, Qingsong ^a   Hou, Mei ^a   Dong, Chunxia ^a   Guo, Rong ^a   Gao, Ge ^a   Ji, Jianguo ^a   Zha, Shan ^e   Lan, Li ^d   Liang, Huanhuan ^b   Xu, Dongyi ^a  

^a PEKING UNIVERSITY   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c WUHAN UNIVERSITY   (China)

^d UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^e NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APRATAXIN; APTX POLYNUCLEOTIDE KINASE PHOSPHATASE LIKE FACTOR; DNA; DNA DEPENDENT PROTEIN KINASE; DNA TOPOISOMERASE (ATP HYDROLYSING); HETERODIMER; HOMODIMER; KU ANTIGEN; MULTIPROTEIN COMPLEX; PAXX PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYNUCLEOTIDE KINASE PHOSPHATASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; XRCC4 LIKE FACTOR; XRCC4 PROTEIN; ATP DEPENDENT DNA LIGASE; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; DNA LIGASE; NHEJ1 PROTEIN, HUMAN; PAXX PROTEIN, HUMAN; PROTEIN BINDING; XRCC4 PROTEIN, HUMAN; XRCC6 PROTEIN, HUMAN;

CRYSTAL STRUCTURE; DNA; EPISTASIS; GENETIC ANALYSIS; INHIBITOR; IONIZATION;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURVIVAL; CRYSTAL STRUCTURE; DNA BINDING; DNA END JOINING REPAIR; DNA PROTEIN COMPLEX; DOUBLE STRANDED DNA BREAK; EPISTASIS; GENE INTERACTION; GENE TARGETING; GENETIC ANALYSIS; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; PARALOGY; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN PURIFICATION; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; CHICKEN; MASS SPECTROMETRY; METABOLISM; MOLECULAR MODEL; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURAL HOMOLOGY; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIGENS, NUCLEAR; CELL LINE; CHICKENS; CRYSTALLOGRAPHY, X-RAY; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA LIGASE ATP; DNA LIGASES; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; KU AUTOANTIGEN; MASS SPECTROMETRY; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 84923107266     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7233     Document Type: Article

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