Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

Blood

Volumn 127, Issue 12, 2016, Pages 1575-1586

  Schulze, Isabell ^a   Rohde, Christian ^a   Scheller Wendorff, Marina ^a   Bäumer, Nicole ^b   Krause, Annika ^b   Herbst, Friederike ^c   Riemke, Pia ^b   Hebestreit, Katja ^b   Tschanter, Petra ^a   Lin, Qiong ^d   Linhart, Heinz ^c   Godley, Lucy A ^e   Glimm, Hanno ^c   Dugas, Martin ^b   Wagner, Wolfgang ^d   Berdel, Wolfgang E ^b   Rosenbauer, Frank ^b   Müller Tidow, Carsten ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d RWTH AACHEN UNIVERSITY   (Germany)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA METHYLTRANSFERASE 3B; MYC PROTEIN; PROTEIN BCL 2; DNA (CYTOSINE 5) METHYLTRANSFERASE;

ACUTE MYELOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; DNA METHYLATION; GENOTYPE; HEMATOPOIESIS; LATENT PERIOD; LEUKEMIA STEM CELL; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; SURVIVAL; TRANSGENE; ANIMAL; C57BL MOUSE; CANCER STEM CELL; CARCINOGENESIS; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; HUMAN; LEUKEMIA; LEUKEMIA, MYELOID, ACUTE; METABOLISM; PATHOLOGY; PROGNOSIS; PROMOTER REGION;

ANIMALS; CARCINOGENESIS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GENE EXPRESSION REGULATION, LEUKEMIC; GENE KNOCK-IN TECHNIQUES; HEMATOPOIESIS; HUMANS; LEUKEMIA; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, INBRED C57BL; NEOPLASTIC STEM CELLS; PROGNOSIS; PROMOTER REGIONS, GENETIC;

EID: 84962252715     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-07-655928     Document Type: Article

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