Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia

PLoS Genetics

Volumn 8, Issue 6, 2012, Pages

  Akalin, Altuna ^a   Garrett Bakelman, Francine E ^a   Kormaksson, Matthias ^a   Busuttil, Jennifer ^a   Zhang, Lu ^b   Khrebtukova, Irina ^b   Milne, Thomas A ^c   Huang, Yongsheng ^d   Biswas, Debabrata ^e   Hess, Jay L ^d   Allis, C David ^e   Roeder, Robert G ^e   Valk, Peter J M ^f   Löwenberg, Bob ^f   Delwel, Ruud ^f   Fernandez, Hugo F ^g   Paietta, Elisabeth ^h   Tallman, Martin S ⁱ   Schroth, Gary P ^b   Mason, Christopher E ^a   Melnick, Ari ^a   Figueroa, Maria E ^d   more..

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b ILLUMINA INC   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

^f ERASMUS MEDICAL CENTER   (Netherlands)

^g H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^h ALBERT EINSTEIN CANCER CENTER   (United States)

ⁱ MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; MIXED LINEAGE LEUKEMIA PROTEIN; IDH1 PROTEIN, HUMAN; ISOCITRATE DEHYDROGENASE; MLL PROTEIN, HUMAN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BASE PAIRING; BONE MARROW; CANCER CLASSIFICATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOSS; GENE TRANSLOCATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; INTRON; MIXED LINEAGE LEUKEMIA GENE; ONCOGENE; PROMOTER REGION; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION SITE; CELL STRAIN HCT116; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HCT116 CELLS; HUMANS; ISOCITRATE DEHYDROGENASE; LEUKEMIA, MYELOID, ACUTE; MOLECULAR SEQUENCE DATA; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 84864031521     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002781     Document Type: Article

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