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Volumn 121, Issue 11, 2013, Pages 2059-2063

Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DNA (CYTOSINE 5) METHYLTRANSFERASE; ISOPROTEIN; MYC PROTEIN; MYC PROTEIN, MOUSE;

EID: 84877595762     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-04-421065     Document Type: Article
Times cited : (43)

References (21)
  • 2
    • 0033753779 scopus 로고    scopus 로고
    • The dna methyltransferases of mammals
    • Bestor TH. The DNA methyltransferases of mammals. Hum Mol Genet. 2000;9(16): 2395-2402.
    • (2000) Hum Mol Genet , vol.9 , Issue.16 , pp. 2395-2402
    • Bestor, T.H.1
  • 3
    • 33749019499 scopus 로고    scopus 로고
    • Expression of delta dnmt3b variants and its association with promoter methylation of p16 and rassf1a in primary non-small cell lung cancer
    • Wang J, Walsh G, Liu DD, et al. Expression of Delta DNMT3B variants and its association with promoter methylation of p16 and RASSF1A in primary non-small cell lung cancer. Cancer Res. 2006;66(17):8361-8366.
    • (2006) Cancer Res. , vol.66 , Issue.17 , pp. 8361-8366
    • Wang, J.1    Walsh, G.2    Liu, D.D.3
  • 4
    • 34547935029 scopus 로고    scopus 로고
    • Cancer cells express aberrant dnmt3b transcripts encoding truncated proteins
    • Ostler KR, Davis EM, Payne SL, et al. Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Oncogene. 2007;26 (38):5553-5563.
    • (2007) Oncogene , vol.26 , Issue.38 , pp. 5553-5563
    • Ostler, K.R.1    Davis, E.M.2    Payne, S.L.3
  • 5
    • 77955038710 scopus 로고    scopus 로고
    • Dnmt3b7, a truncated dnmt3b isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis
    • Shah MY, Vasanthakumar A, Barnes NY, et al. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Res. 2010;70(14):5840-5850.
    • (2010) Cancer Res. , vol.70 , Issue.14 , pp. 5840-5850
    • Shah, M.Y.1    Vasanthakumar, A.2    Barnes, N.Y.3
  • 6
    • 0022380768 scopus 로고
    • The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
    • Adams JM, Harris AW, Pinkert CA, et al. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature. 1985;318(6046): 533-538.
    • (1985) Nature , vol.318 , Issue.6046 , pp. 533-538
    • Adams, J.M.1    Harris, A.W.2    Pinkert, C.A.3
  • 7
    • 0033615717 scopus 로고    scopus 로고
    • Dna methyltransferases dnmt3a and dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, et al. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell. 1999;99(3):247-257.
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3
  • 8
    • 33645735015 scopus 로고    scopus 로고
    • Roles for dnmt3b in mammalian development: A mouse model for the icf syndrome
    • Ueda Y, Okano M, Williams C, et al. Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome. Development. 2006; 133(6):1183-1192.
    • (2006) Development , vol.133 , Issue.6 , pp. 1183-1192
    • Ueda, Y.1    Okano, M.2    Williams, C.3
  • 9
    • 79958074728 scopus 로고    scopus 로고
    • Modulation of dnmt3b function in vitro by interactions with dnmt3l, dnmt3a and dnmt3b splice variants
    • Van Emburgh BO, Robertson KD. Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants. Nucleic Acids Res. 2011;39(12):4984-5002.
    • (2011) Nucleic Acids Res. , vol.39 , Issue.12 , pp. 4984-5002
    • Van Emburgh, B.O.1    Robertson, K.D.2
  • 10
    • 12244279345 scopus 로고    scopus 로고
    • Specific method for the determination of genomic dna methylation by liquid chromatography-electrospray ionization tandem mass spectrometry
    • Song L, James SR, Kazim L, et al. Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry. Anal Chem. 2005;77(2):504-510.
    • (2005) Anal Chem , vol.77 , Issue.2 , pp. 504-510
    • Song, L.1    James, S.R.2    Kazim, L.3
  • 11
    • 84855433323 scopus 로고    scopus 로고
    • Loss of dnmt3b function upregulates the tumor modifier ment and accelerates mouse lymphomagenesis
    • Hlady RA, Novakova S, Opavska J, et al. Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis. J Clin Invest. 2012;122(1):163-177.
    • (2012) J Clin Invest , vol.122 , Issue.1 , pp. 163-177
    • Hlady, R.A.1    Novakova, S.2    Opavska, J.3
  • 12
    • 81055130253 scopus 로고    scopus 로고
    • Deletion of the de novo dna methyltransferase dnmt3a promotes lung tumor progression
    • Gao Q, Steine EJ, Barrasa MI, et al. Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression. Proc Natl Acad Sci USA. 2011;108(44):18061-18066.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.44 , pp. 18061-18066
    • Gao, Q.1    Steine, E.J.2    Barrasa, M.I.3
  • 13
    • 77954089584 scopus 로고    scopus 로고
    • Array-based genomic resequencing of human leukemia
    • Yamashita Y, Yuan J, Suetake I, et al. Array-based genomic resequencing of human leukemia. Oncogene. 2010;29(25):3723-3731.
    • (2010) Oncogene , vol.29 , Issue.25 , pp. 3723-3731
    • Yamashita, Y.1    Yuan, J.2    Suetake, I.3
  • 14
    • 78649906060 scopus 로고    scopus 로고
    • Dnmt3a mutations in acute myeloid leukemia
    • Ley TJ, Ding L, Walter MJ, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med. 2010;363(25):2424-2433.
    • (2010) N Engl J Med. , vol.363 , Issue.25 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 15
    • 79953176952 scopus 로고    scopus 로고
    • Exome sequencing identifies somatic mutations of dna methyltransferase gene dnmt3a in acute monocytic leukemia
    • Yan XJ, Xu J, Gu ZH, et al. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011;43(4):309-315.
    • (2011) Nat Genet , vol.43 , Issue.4 , pp. 309-315
    • Yan, X.J.1    Xu, J.2    Gu, Z.H.3
  • 16
    • 34848812553 scopus 로고    scopus 로고
    • Cpg island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells
    • Opavsky R, Wang SH, Trikha P, et al. CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. PLoS Genet. 2007;3(9):1757-1769.
    • (2007) Plos Genet. , vol.3 , Issue.9 , pp. 1757-1769
    • Opavsky, R.1    Wang, S.H.2    Trikha, P.3
  • 17
    • 80053376487 scopus 로고    scopus 로고
    • Dna methyltransferase 1 and dna methylation patterning contribute to germinal center b-cell differentiation
    • Shaknovich R, Cerchietti L, Tsikitas L, et al. DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. Blood. 2011;118(13): 3559-3569.
    • (2011) Blood , vol.118 , Issue.13 , pp. 3559-3569
    • Shaknovich, R.1    Cerchietti, L.2    Tsikitas, L.3
  • 18
    • 13444270415 scopus 로고    scopus 로고
    • Myc represses transcription through recruitment of dna methyltransferase corepressor
    • Brenner C, Deplus R, Didelot C, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J. 2005;24(2):336-346.
    • (2005) EMBO J. , vol.24 , Issue.2 , pp. 336-346
    • Brenner, C.1    Deplus, R.2    Didelot, C.3
  • 19
    • 24744470281 scopus 로고    scopus 로고
    • In vivo transcriptional regulation of n-myc target genes is controlled by e-box methylation
    • Perini G, Diolaiti D, Porro A, et al. In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation. Proc Natl Acad Sci USA. 2005;102(34):12117-12122.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.34 , pp. 12117-12122
    • Perini, G.1    Diolaiti, D.2    Porro, A.3
  • 20
    • 70350010350 scopus 로고    scopus 로고
    • Epigenetic silencing of the rassf1a tumor suppressor gene through hoxb3-mediated induction of dnmt3b expression
    • Palakurthy RK, Wajapeyee N, Santra MK, et al. Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression. Mol Cell. 2009; 36(2):219-230.
    • (2009) Mol Cell , vol.36 , Issue.2 , pp. 219-230
    • Palakurthy, R.K.1    Wajapeyee, N.2    Santra, M.K.3
  • 21
    • 80055000824 scopus 로고    scopus 로고
    • Rnai screen identifies brd4 as a therapeutic target in acute myeloid leukaemia
    • Zuber J, Shi J, Wang E, et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature. 2011;478(7370): 524-528.
    • (2011) Nature , vol.478 , Issue.7370 , pp. 524-528
    • Zuber, J.1    Shi, J.2    Wang, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.