-
1
-
-
68449084682
-
MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development
-
G. Alam, H. Cui, H. Shi, L. Yang, J. Ding, L. Mao, W.A. Maltese, and H.F. Ding MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development Am. J. Pathol. 175 2009 856 866
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 856-866
-
-
Alam, G.1
Cui, H.2
Shi, H.3
Yang, L.4
Ding, J.5
Mao, L.6
Maltese, W.A.7
Ding, H.F.8
-
2
-
-
33846678695
-
The ABCA subfamily - Gene and protein structures, functions and associated hereditary diseases
-
C. Albrecht, and E. Viturro The ABCA subfamily - gene and protein structures, functions and associated hereditary diseases Pflug. Arch. 453 2007 581 589
-
(2007)
Pflug. Arch.
, vol.453
, pp. 581-589
-
-
Albrecht, C.1
Viturro, E.2
-
4
-
-
84860669151
-
Targeting MDR in breast and lung cancer: Discriminating its potential importance from the failure of drug resistance reversal studies
-
L. Amiri-Kordestani, A. Basseville, K. Kurdziel, A.T. Fojo, and S.E. Bates Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies Drug Resist. Updates 15 2012 50 61
-
(2012)
Drug Resist. Updates
, vol.15
, pp. 50-61
-
-
Amiri-Kordestani, L.1
Basseville, A.2
Kurdziel, K.3
Fojo, A.T.4
Bates, S.E.5
-
5
-
-
0024538964
-
Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype
-
Y.G. Assaraf, A. Molina, and R.T. Schimke Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype J. Natl. Cancer Inst. 81 1989 290 294
-
(1989)
J. Natl. Cancer Inst.
, vol.81
, pp. 290-294
-
-
Assaraf, Y.G.1
Molina, A.2
Schimke, R.T.3
-
6
-
-
0024467350
-
Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate
-
Y.G. Assaraf, A. Molina, and R.T. Schimke Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate J. Biol. Chem. 264 1989 18326 18334
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 18326-18334
-
-
Assaraf, Y.G.1
Molina, A.2
Schimke, R.T.3
-
7
-
-
22344446049
-
Analysis of the in vivo functions of Mrp3
-
M.G. Belinsky, P.A. Dawson, I. Shchaveleva, L.J. Bain, R. Wang, V. Ling, Z.S. Chen, A. Grinberg, H. Westphal, A. Klein-Szanto, A. Lerro, and G.D. Kruh Analysis of the in vivo functions of Mrp3 Mol. Pharmacol. 68 2005 160 168
-
(2005)
Mol. Pharmacol.
, vol.68
, pp. 160-168
-
-
Belinsky, M.G.1
Dawson, P.A.2
Shchaveleva, I.3
Bain, L.J.4
Wang, R.5
Ling, V.6
Chen, Z.S.7
Grinberg, A.8
Westphal, H.9
Klein-Szanto, A.10
Lerro, A.11
Kruh, G.D.12
-
8
-
-
33846441251
-
Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue-induced damage
-
M.G. Belinsky, P. Guo, K. Lee, F. Zhou, E. Kotova, A. Grinberg, H. Westphal, I. Shchaveleva, A. Klein-Szanto, J.M. Gallo, and G.D. Kruh Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue-induced damage Cancer Res. 67 2007 262 268
-
(2007)
Cancer Res.
, vol.67
, pp. 262-268
-
-
Belinsky, M.G.1
Guo, P.2
Lee, K.3
Zhou, F.4
Kotova, E.5
Grinberg, A.6
Westphal, H.7
Shchaveleva, I.8
Klein-Szanto, A.9
Gallo, J.M.10
Kruh, G.D.11
-
9
-
-
0029049468
-
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action
-
D.M. Bollag, P.A. McQueney, J. Zhu, O. Hensens, L. Koupal, J. Liesch, M. Goetz, E. Lazarides, and C.M. Woods Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action Cancer Res. 55 1995 2325 2333
-
(1995)
Cancer Res.
, vol.55
, pp. 2325-2333
-
-
Bollag, D.M.1
McQueney, P.A.2
Zhu, J.3
Hensens, O.4
Koupal, L.5
Liesch, J.6
Goetz, M.7
Lazarides, E.8
Woods, C.M.9
-
10
-
-
0030062653
-
Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity
-
M.J. Borgnia, G.D. Eytan, and Y.G. Assaraf Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity J. Biol. Chem. 271 1996 3163 3171
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3163-3171
-
-
Borgnia, M.J.1
Eytan, G.D.2
Assaraf, Y.G.3
-
11
-
-
66049093214
-
Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2
-
E.E. Bram, Y. Adar, N. Mesika, M. Sabisz, A. Skladanowski, and Y.G. Assaraf Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2 Mol. Pharmacol. 75 2009 1149 1159
-
(2009)
Mol. Pharmacol.
, vol.75
, pp. 1149-1159
-
-
Bram, E.E.1
Adar, Y.2
Mesika, N.3
Sabisz, M.4
Skladanowski, A.5
Assaraf, Y.G.6
-
12
-
-
72949085978
-
Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance
-
E.E. Bram, M. Stark, S. Raz, and Y.G. Assaraf Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance Neoplasia 11 2009 1359 1370
-
(2009)
Neoplasia
, vol.11
, pp. 1359-1370
-
-
Bram, E.E.1
Stark, M.2
Raz, S.3
Assaraf, Y.G.4
-
13
-
-
0035955452
-
Interaction between two adapter proteins, PAG and EBP50: A possible link between membrane rafts and actin cytoskeleton
-
N. Brdickova, T. Brdicka, L. Andera, J. Spicka, P. Angelisova, S.L. Milgram, and V. Horejsi Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton FEBS Lett. 507 2001 133 136
-
(2001)
FEBS Lett.
, vol.507
, pp. 133-136
-
-
Brdickova, N.1
Brdicka, T.2
Andera, L.3
Spicka, J.4
Angelisova, P.5
Milgram, S.L.6
Horejsi, V.7
-
14
-
-
0021261878
-
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
-
G.M. Brodeur, R.C. Seeger, M. Schwab, H.E. Varmus, and J.M. Bishop Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage Science 224 1984 1121 1124
-
(1984)
Science
, vol.224
, pp. 1121-1124
-
-
Brodeur, G.M.1
Seeger, R.C.2
Schwab, M.3
Varmus, H.E.4
Bishop, J.M.5
-
15
-
-
0032813808
-
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
-
A. Brooks-Wilson, M. Marcil, S.M. Clee, L.H. Zhang, K. Roomp, M. van Dam, L. Yu, C. Brewer, J.A. Collins, H.O. Molhuizen, O. Loubser, B.F. Ouelette, K. Fichter, K.J. Ashbourne-Excoffon, C.W. Sensen, S. Scherer, S. Mott, M. Denis, D. Martindale, J. Frohlich, K. Morgan, B. Koop, S. Pimstone, J.J. Kastelein, J. Genest Jr., and M.R. Hayden Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency Nat. Genet. 22 1999 336 345
-
(1999)
Nat. Genet.
, vol.22
, pp. 336-345
-
-
Brooks-Wilson, A.1
Marcil, M.2
Clee, S.M.3
Zhang, L.H.4
Roomp, K.5
Van Dam, M.6
Yu, L.7
Brewer, C.8
Collins, J.A.9
Molhuizen, H.O.10
Loubser, O.11
Ouelette, B.F.12
Fichter, K.13
Ashbourne-Excoffon, K.J.14
Sensen, C.W.15
Scherer, S.16
Mott, S.17
Denis, M.18
Martindale, D.19
Frohlich, J.20
Morgan, K.21
Koop, B.22
Pimstone, S.23
Kastelein, J.J.24
Genest, J.25
Hayden, M.R.26
more..
-
16
-
-
0037314795
-
RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response
-
H. Burger, J.A. Foekens, M.P. Look, M.E. Meijer-van Gelder, J.G. Klijn, E.A. Wiemer, G. Stoter, and K. Nooter RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response Clin. Cancer Res. 9 2003 827 836
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 827-836
-
-
Burger, H.1
Foekens, J.A.2
Look, M.P.3
Meijer Van Gelder, M.E.4
Klijn, J.G.5
Wiemer, E.A.6
Stoter, G.7
Nooter, K.8
-
17
-
-
69249094554
-
Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma
-
C.A. Burkhart, F. Watt, J. Murray, M. Pajic, A. Prokvolit, C. Xue, C. Flemming, J. Smith, A. Purmal, N. Isachenko, P.G. Komarov, K.V. Gurova, A.C. Sartorelli, G.M. Marshall, M.D. Norris, A.V. Gudkov, and M. Haber Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma Cancer Res. 69 2009 6573 6580
-
(2009)
Cancer Res.
, vol.69
, pp. 6573-6580
-
-
Burkhart, C.A.1
Watt, F.2
Murray, J.3
Pajic, M.4
Prokvolit, A.5
Xue, C.6
Flemming, C.7
Smith, J.8
Purmal, A.9
Isachenko, N.10
Komarov, P.G.11
Gurova, K.V.12
Sartorelli, A.C.13
Marshall, G.M.14
Norris, M.D.15
Gudkov, A.V.16
Haber, M.17
-
18
-
-
0022972654
-
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
-
C.J. Chen, J.E. Chin, K. Ueda, D.P. Clark, I. Pastan, M.M. Gottesman, and I.B. Roninson Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells Cell 47 1986 381 389
-
(1986)
Cell
, vol.47
, pp. 381-389
-
-
Chen, C.J.1
Chin, J.E.2
Ueda, K.3
Clark, D.P.4
Pastan, I.5
Gottesman, M.M.6
Roninson, I.B.7
-
19
-
-
0032530533
-
Taxol resistance mediated by transfection of the liver-specific sister gene of P-glycoprotein
-
S. Childs, R.L. Yeh, D. Hui, and V. Ling Taxol resistance mediated by transfection of the liver-specific sister gene of P-glycoprotein Cancer Res. 58 1998 4160 4167
-
(1998)
Cancer Res.
, vol.58
, pp. 4160-4167
-
-
Childs, S.1
Yeh, R.L.2
Hui, D.3
Ling, V.4
-
20
-
-
33645868291
-
Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2)
-
X.Y. Chu, J.R. Strauss, M.A. Mariano, J. Li, D.J. Newton, X. Cai, R.W. Wang, J. Yabut, D.P. Hartley, D.C. Evans, and R. Evers Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2) J. Pharmacol. Exp. Ther. 317 2006 579 589
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.317
, pp. 579-589
-
-
Chu, X.Y.1
Strauss, J.R.2
Mariano, M.A.3
Li, J.4
Newton, D.J.5
Cai, X.6
Wang, R.W.7
Yabut, J.8
Hartley, D.P.9
Evans, D.C.10
Evers, R.11
-
21
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
S.P. Cole, G. Bhardwaj, J.H. Gerlach, J.E. Mackie, C.E. Grant, K.C. Almquist, A.J. Stewart, E.U. Kurz, A.M. Duncan, and R.G. Deeley Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line Science 258 1992 1650 1654
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Duncan, A.M.9
Deeley, R.G.10
-
22
-
-
33745897902
-
Transport of glutathione and glutathione conjugates by MRP1
-
S.P. Cole, and R.G. Deeley Transport of glutathione and glutathione conjugates by MRP1 Trends Pharmacol. Sci. 27 2006 438 446
-
(2006)
Trends Pharmacol. Sci.
, vol.27
, pp. 438-446
-
-
Cole, S.P.1
Deeley, R.G.2
-
23
-
-
0037113346
-
Localisation of breast cancer resistance protein in microvessel endothelium of human brain
-
H.C. Cooray, C.G. Blackmore, L. Maskell, and M.A. Barrand Localisation of breast cancer resistance protein in microvessel endothelium of human brain Neuroreport 13 2002 2059 2063
-
(2002)
Neuroreport
, vol.13
, pp. 2059-2063
-
-
Cooray, H.C.1
Blackmore, C.G.2
Maskell, L.3
Barrand, M.A.4
-
24
-
-
84910084359
-
Multidrug resistance protein 4/ATP binding cassette transporter 4: A new potential therapeutic target for acute myeloid leukemia
-
S. Copsel, A. Bruzzone, M. May, J. Beyrath, V. Wargon, J. Cany, F.G. Russel, C. Shayo, and C. Davio Multidrug resistance protein 4/ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia Oncotarget 5 2014 9308 9321
-
(2014)
Oncotarget
, vol.5
, pp. 9308-9321
-
-
Copsel, S.1
Bruzzone, A.2
May, M.3
Beyrath, J.4
Wargon, V.5
Cany, J.6
Russel, F.G.7
Shayo, C.8
Davio, C.9
-
25
-
-
79953191123
-
Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation
-
S. Copsel, C. Garcia, F. Diez, M. Vermeulem, A. Baldi, L.G. Bianciotti, F.G. Russel, C. Shayo, and C. Davio Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation J. Biol. Chem. 286 2011 6979 6988
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 6979-6988
-
-
Copsel, S.1
Garcia, C.2
Diez, F.3
Vermeulem, M.4
Baldi, A.5
Bianciotti, L.G.6
Russel, F.G.7
Shayo, C.8
Davio, C.9
-
26
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
C. Cordon-Cardo, J.P. O'Brien, D. Casals, L. Rittman-Grauer, J.L. Biedler, M.R. Melamed, and J.R. Bertino Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites Proc. Natl. Acad. Sci. U. S. A. 86 1989 695 698
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
Bertino, J.R.7
-
27
-
-
0024544045
-
The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
-
J.M. Croop, M. Raymond, D. Haber, A. Devault, R.J. Arceci, P. Gros, and D.E. Housman The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues Mol. Cell. Biol. 9 1989 1346 1350
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1346-1350
-
-
Croop, J.M.1
Raymond, M.2
Haber, D.3
Devault, A.4
Arceci, R.J.5
Gros, P.6
Housman, D.E.7
-
28
-
-
33845999250
-
CGMP transport by vesicles from human and mouse erythrocytes
-
C.J. de Wolf, H. Yamaguchi, I. van der Heijden, P.R. Wielinga, S.L. Hundscheid, N. Ono, G.L. Scheffer, M. de Haas, J.D. Schuetz, J. Wijnholds, and P. Borst cGMP transport by vesicles from human and mouse erythrocytes FEBS J. 274 2007 439 450
-
(2007)
FEBS J.
, vol.274
, pp. 439-450
-
-
De Wolf, C.J.1
Yamaguchi, H.2
Van Der Heijden, I.3
Wielinga, P.R.4
Hundscheid, S.L.5
Ono, N.6
Scheffer, G.L.7
De Haas, M.8
Schuetz, J.D.9
Wijnholds, J.10
Borst, P.11
-
29
-
-
30144435485
-
The genetics of ATP-binding cassette transporters
-
M. Dean The genetics of ATP-binding cassette transporters Methods Enzymol. 400 2005 409 429
-
(2005)
Methods Enzymol.
, vol.400
, pp. 409-429
-
-
Dean, M.1
-
30
-
-
16844368698
-
Tumour stem cells and drug resistance
-
M. Dean, T. Fojo, and S. Bates Tumour stem cells and drug resistance Nat. Rev. Cancer 5 2005 275 284
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
31
-
-
31844455959
-
Substrate recognition and transport by multidrug resistance protein 1 (ABCC1)
-
R.G. Deeley, and S.P. Cole Substrate recognition and transport by multidrug resistance protein 1 (ABCC1) FEBS Lett. 580 2006 1103 1111
-
(2006)
FEBS Lett.
, vol.580
, pp. 1103-1111
-
-
Deeley, R.G.1
Cole, S.P.2
-
32
-
-
77954892297
-
Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib
-
M. Dohse, C. Scharenberg, S. Shukla, R.W. Robey, T. Volkmann, J.F. Deeken, C. Brendel, S.V. Ambudkar, A. Neubauer, and S.E. Bates Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib Drug Metab. Dispos. 38 2010 1371 1380
-
(2010)
Drug Metab. Dispos.
, vol.38
, pp. 1371-1380
-
-
Dohse, M.1
Scharenberg, C.2
Shukla, S.3
Robey, R.W.4
Volkmann, T.5
Deeken, J.F.6
Brendel, C.7
Ambudkar, S.V.8
Neubauer, A.9
Bates, S.E.10
-
33
-
-
70350351085
-
Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells
-
W. Dong, S. Vuletic, and J.J. Albers Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells J. Lipid Res. 50 2009 2095 2102
-
(2009)
J. Lipid Res.
, vol.50
, pp. 2095-2102
-
-
Dong, W.1
Vuletic, S.2
Albers, J.J.3
-
34
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
L.A. Doyle, W. Yang, L.V. Abruzzo, T. Krogmann, Y. Gao, A.K. Rishi, and D.D. Ross A multidrug resistance transporter from human MCF-7 breast cancer cells Proc. Natl. Acad. Sci. U. S. A. 95 1998 15665 15670
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
Ross, D.D.7
-
35
-
-
0028020549
-
Transport of polypeptide ionophores into proteoliposomes reconstituted with rat liver P-glycoprotein
-
G.D. Eytan, M.J. Borgnia, R. Regev, and Y.G. Assaraf Transport of polypeptide ionophores into proteoliposomes reconstituted with rat liver P-glycoprotein J. Biol. Chem. 269 1994 26058 26065
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26058-26065
-
-
Eytan, G.D.1
Borgnia, M.J.2
Regev, R.3
Assaraf, Y.G.4
-
36
-
-
20044364737
-
Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: The Austrian Breast and Colorectal Cancer Study Group
-
M. Filipits, G. Pohl, M. Rudas, O. Dietze, S. Lax, R. Grill, R. Pirker, C.C. Zielinski, H. Hausmaninger, E. Kubista, H. Samonigg, and R. Jakesz Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group J. Clin. Oncol. 23 2005 1161 1168
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 1161-1168
-
-
Filipits, M.1
Pohl, G.2
Rudas, M.3
Dietze, O.4
Lax, S.5
Grill, R.6
Pirker, R.7
Zielinski, C.C.8
Hausmaninger, H.9
Kubista, E.10
Samonigg, H.11
Jakesz, R.12
-
37
-
-
9244261944
-
Tissue distribution of the multidrug resistance protein
-
M.J. Flens, G.J. Zaman, P. van der Valk, M.A. Izquierdo, A.B. Schroeijers, G.L. Scheffer, P. van der Groep, M. de Haas, C.J. Meijer, and R.J. Scheper Tissue distribution of the multidrug resistance protein Am. J. Pathol. 148 1996 1237 1247
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1237-1247
-
-
Flens, M.J.1
Zaman, G.J.2
Van Der Valk, P.3
Izquierdo, M.A.4
Schroeijers, A.B.5
Scheffer, G.L.6
Van Der Groep, P.7
De Haas, M.8
Meijer, C.J.9
Scheper, R.J.10
-
39
-
-
0023019651
-
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
-
J.H. Gerlach, J.A. Endicott, P.F. Juranka, G. Henderson, F. Sarangi, K.L. Deuchars, and V. Ling Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance Nature 324 1986 485 489
-
(1986)
Nature
, vol.324
, pp. 485-489
-
-
Gerlach, J.H.1
Endicott, J.A.2
Juranka, P.F.3
Henderson, G.4
Sarangi, F.5
Deuchars, K.L.6
Ling, V.7
-
40
-
-
26444436944
-
Disruption of Abcc6 in the mouse: Novel insight in the pathogenesis of pseudoxanthoma elasticum
-
T.G. Gorgels, X. Hu, G.L. Scheffer, A.C. van der Wal, J. Toonstra, P.T. de Jong, T.H. van Kuppevelt, C.N. Levelt, A. de Wolf, W.J. Loves, R.J. Scheper, R. Peek, and A.A. Bergen Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum Hum. Mol. Genet. 14 2005 1763 1773
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1763-1773
-
-
Gorgels, T.G.1
Hu, X.2
Scheffer, G.L.3
Van Der Wal, A.C.4
Toonstra, J.5
De Jong, P.T.6
Van Kuppevelt, T.H.7
Levelt, C.N.8
De Wolf, A.9
Loves, W.J.10
Scheper, R.J.11
Peek, R.12
Bergen, A.A.13
-
41
-
-
42549132292
-
Effects of drug efflux proteins and topoisomerase i mutations on the camptothecin analogue gimatecan
-
M.K. Gounder, A.S. Nazar, A. Saleem, P. Pungaliya, D. Kulkarni, R. Versace, and E.H. Rubin Effects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan Investig. New Drugs 26 2008 205 213
-
(2008)
Investig. New Drugs
, vol.26
, pp. 205-213
-
-
Gounder, M.K.1
Nazar, A.S.2
Saleem, A.3
Pungaliya, P.4
Kulkarni, D.5
Versace, R.6
Rubin, E.H.7
-
42
-
-
0022993652
-
Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
-
P. Gros, J. Croop, and D. Housman Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins Cell 47 1986 371 380
-
(1986)
Cell
, vol.47
, pp. 371-380
-
-
Gros, P.1
Croop, J.2
Housman, D.3
-
43
-
-
33645747683
-
Association of high-level MRP1 expression with poor clinical outcome in a large prospective study of primary neuroblastoma
-
M. Haber, J. Smith, S.B. Bordow, C. Flemming, S.L. Cohn, W.B. London, G.M. Marshall, and M.D. Norris Association of high-level MRP1 expression with poor clinical outcome in a large prospective study of primary neuroblastoma J. Clin. Oncol. 24 2006 1546 1553
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 1546-1553
-
-
Haber, M.1
Smith, J.2
Bordow, S.B.3
Flemming, C.4
Cohn, S.L.5
London, W.B.6
Marshall, G.M.7
Norris, M.D.8
-
44
-
-
4344606588
-
Mechanisms of embryonal tumor initiation: Distinct roles for MycN expression and MYCN amplification
-
L.M. Hansford, W.D. Thomas, J.M. Keating, C.A. Burkhart, A.E. Peaston, M.D. Norris, M. Haber, P.J. Armati, W.A. Weiss, and G.M. Marshall Mechanisms of embryonal tumor initiation: distinct roles for MycN expression and MYCN amplification Proc. Natl. Acad. Sci. U. S. A. 101 2004 12664 12669
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 12664-12669
-
-
Hansford, L.M.1
Thomas, W.D.2
Keating, J.M.3
Burkhart, C.A.4
Peaston, A.E.5
Norris, M.D.6
Haber, M.7
Armati, P.J.8
Weiss, W.A.9
Marshall, G.M.10
-
45
-
-
84905247012
-
ABCA transporter gene expression and poor outcome in epithelial ovarian cancer
-
E.L. Hedditch, B. Gao, A.J. Russell, Y. Lu, C. Emmanuel, J. Beesley, S.E. Johnatty, X. Chen, P. Harnett, J. George, R.T. Williams, C. Flemming, D. Lambrechts, E. Despierre, S. Lambrechts, I. Vergote, B. Karlan, J. Lester, S. Orsulic, C. Walsh, P. Fasching, M.W. Beckmann, A.B. Ekici, A. Hein, K. Matsuo, S. Hosono, T. Nakanishi, Y. Yatabe, T. Pejovic, Y. Bean, F. Heitz, P. Harter, A. du Bois, I. Schwaab, E. Hogdall, S.K. Kjaer, A. Jensen, C. Hogdall, L. Lundvall, S.A. Engelholm, B. Brown, J. Flanagan, M.D. Metcalf, N. Siddiqui, T. Sellers, B. Fridley, J. Cunningham, J. Schildkraut, E. Iversen, R.P. Weber, A. Berchuck, E. Goode, D.D. Bowtell, G. Chenevix-Trench, A. deFazio, M.D. Norris, S. MacGregor, M. Haber, and M.J. Henderson ABCA transporter gene expression and poor outcome in epithelial ovarian cancer J. Natl. Cancer Inst. 106 2014
-
(2014)
J. Natl. Cancer Inst.
, vol.106
-
-
Hedditch, E.L.1
Gao, B.2
Russell, A.J.3
Lu, Y.4
Emmanuel, C.5
Beesley, J.6
Johnatty, S.E.7
Chen, X.8
Harnett, P.9
George, J.10
Williams, R.T.11
Flemming, C.12
Lambrechts, D.13
Despierre, E.14
Lambrechts, S.15
Vergote, I.16
Karlan, B.17
Lester, J.18
Orsulic, S.19
Walsh, C.20
Fasching, P.21
Beckmann, M.W.22
Ekici, A.B.23
Hein, A.24
Matsuo, K.25
Hosono, S.26
Nakanishi, T.27
Yatabe, Y.28
Pejovic, T.29
Bean, Y.30
Heitz, F.31
Harter, P.32
Du Bois, A.33
Schwaab, I.34
Hogdall, E.35
Kjaer, S.K.36
Jensen, A.37
Hogdall, C.38
Lundvall, L.39
Engelholm, S.A.40
Brown, B.41
Flanagan, J.42
Metcalf, M.D.43
Siddiqui, N.44
Sellers, T.45
Fridley, B.46
Cunningham, J.47
Schildkraut, J.48
Iversen, E.49
Weber, R.P.50
Berchuck, A.51
Goode, E.52
Bowtell, D.D.53
Chenevix-Trench, G.54
DeFazio, A.55
Norris, M.D.56
MacGregor, S.57
Haber, M.58
Henderson, M.J.59
more..
-
46
-
-
84861993942
-
Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: Implications for the emergence and reversal of cancer drug resistance
-
C. Hegedus, K. Truta-Feles, G. Antalffy, G. Varady, K. Nemet, C. Ozvegy-Laczka, G. Keri, L. Orfi, G. Szakacs, J. Settleman, A. Varadi, and B. Sarkadi Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance Biochem. Pharmacol. 84 2012 260 267
-
(2012)
Biochem. Pharmacol.
, vol.84
, pp. 260-267
-
-
Hegedus, C.1
Truta-Feles, K.2
Antalffy, G.3
Varady, G.4
Nemet, K.5
Ozvegy-Laczka, C.6
Keri, G.7
Orfi, L.8
Szakacs, G.9
Settleman, J.10
Varadi, A.11
Sarkadi, B.12
-
47
-
-
80051996580
-
ABCC multidrug transporters in childhood neuroblastoma: Clinical and biological effects independent of cytotoxic drug efflux
-
M.J. Henderson, M. Haber, A. Porro, M.A. Munoz, N. Iraci, C. Xue, J. Murray, C.L. Flemming, J. Smith, J.I. Fletcher, S. Gherardi, C.K. Kwek, A.J. Russell, E. Valli, W.B. London, A.B. Buxton, L.J. Ashton, A.C. Sartorelli, S.L. Cohn, M. Schwab, G.M. Marshall, G. Perini, and M.D. Norris ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux J. Natl. Cancer Inst. 103 2011 1236 1251
-
(2011)
J. Natl. Cancer Inst.
, vol.103
, pp. 1236-1251
-
-
Henderson, M.J.1
Haber, M.2
Porro, A.3
Munoz, M.A.4
Iraci, N.5
Xue, C.6
Murray, J.7
Flemming, C.L.8
Smith, J.9
Fletcher, J.I.10
Gherardi, S.11
Kwek, C.K.12
Russell, A.J.13
Valli, E.14
London, W.B.15
Buxton, A.B.16
Ashton, L.J.17
Sartorelli, A.C.18
Cohn, S.L.19
Schwab, M.20
Marshall, G.M.21
Perini, G.22
Norris, M.D.23
more..
-
48
-
-
84877934494
-
PPARdelta promotes oncogenic redirection of TGF-beta1 signaling through the activation of the ABCA1-Cav1 pathway
-
N.G. Her, S.I. Jeong, K. Cho, T.K. Ha, J. Han, K.P. Ko, S.K. Park, J.H. Lee, M.G. Lee, B.K. Ryu, and S.G. Chi PPARdelta promotes oncogenic redirection of TGF-beta1 signaling through the activation of the ABCA1-Cav1 pathway Cell Cycle 12 2013 1521 1535
-
(2013)
Cell Cycle
, vol.12
, pp. 1521-1535
-
-
Her, N.G.1
Jeong, S.I.2
Cho, K.3
Ha, T.K.4
Han, J.5
Ko, K.P.6
Park, S.K.7
Lee, J.H.8
Lee, M.G.9
Ryu, B.K.10
Chi, S.G.11
-
49
-
-
0033152212
-
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2
-
J.H. Hooijberg, H.J. Broxterman, M. Kool, Y.G. Assaraf, G.J. Peters, P. Noordhuis, R.J. Scheper, P. Borst, H.M. Pinedo, and G. Jansen Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2 Cancer Res. 59 1999 2532 2535
-
(1999)
Cancer Res.
, vol.59
, pp. 2532-2535
-
-
Hooijberg, J.H.1
Broxterman, H.J.2
Kool, M.3
Assaraf, Y.G.4
Peters, G.J.5
Noordhuis, P.6
Scheper, R.J.7
Borst, P.8
Pinedo, H.M.9
Jansen, G.10
-
50
-
-
79956157982
-
Contribution of Abcc10 (Mrp7) to in vivo paclitaxel resistance as assessed in Abcc10(-/-) mice
-
E.A. Hopper-Borge, T. Churchill, C. Paulose, E. Nicolas, J.D. Jacobs, O. Ngo, Y. Kuang, A. Grinberg, H. Westphal, Z.S. Chen, A.J. Klein-Szanto, M.G. Belinsky, and G.D. Kruh Contribution of Abcc10 (Mrp7) to in vivo paclitaxel resistance as assessed in Abcc10(-/-) mice Cancer Res. 71 2011 3649 3657
-
(2011)
Cancer Res.
, vol.71
, pp. 3649-3657
-
-
Hopper-Borge, E.A.1
Churchill, T.2
Paulose, C.3
Nicolas, E.4
Jacobs, J.D.5
Ngo, O.6
Kuang, Y.7
Grinberg, A.8
Westphal, H.9
Chen, Z.S.10
Klein-Szanto, A.J.11
Belinsky, M.G.12
Kruh, G.D.13
-
51
-
-
59149089885
-
The role of ATP binding cassette transporters in tissue defense and organ regeneration
-
M. Huls, F.G. Russel, and R. Masereeuw The role of ATP binding cassette transporters in tissue defense and organ regeneration J. Pharmacol. Exp. Ther. 328 2009 3 9
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.328
, pp. 3-9
-
-
Huls, M.1
Russel, F.G.2
Masereeuw, R.3
-
52
-
-
84930221642
-
N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids
-
R.S. Jansen, R. Addie, R. Merkx, A. Fish, S. Mahakena, O.B. Bleijerveld, M. Altelaar, L. Ijlst, R.J. Wanders, P. Borst, and K. van de Wetering N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids Proc. Natl. Acad. Sci. U. S. A. 112 2015 6601 6606
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, pp. 6601-6606
-
-
Jansen, R.S.1
Addie, R.2
Merkx, R.3
Fish, A.4
Mahakena, S.5
Bleijerveld, O.B.6
Altelaar, M.7
Ijlst, L.8
Wanders, R.J.9
Borst, P.10
Van De Wetering, K.11
-
53
-
-
0037180446
-
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
-
J.W. Jonker, M. Buitelaar, E. Wagenaar, M.A. Van Der Valk, G.L. Scheffer, R.J. Scheper, T. Plosch, F. Kuipers, R.P. Elferink, H. Rosing, J.H. Beijnen, and A.H. Schinkel The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria Proc. Natl. Acad. Sci. U. S. A. 99 2002 15649 15654
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 15649-15654
-
-
Jonker, J.W.1
Buitelaar, M.2
Wagenaar, E.3
Van Der Valk, M.A.4
Scheffer, G.L.5
Scheper, R.J.6
Plosch, T.7
Kuipers, F.8
Elferink, R.P.9
Rosing, H.10
Beijnen, J.H.11
Schinkel, A.H.12
-
54
-
-
14644409841
-
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
-
J.W. Jonker, G. Merino, S. Musters, A.E. van Herwaarden, E. Bolscher, E. Wagenaar, E. Mesman, T.C. Dale, and A.H. Schinkel The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk Nat. Med. 11 2005 127 129
-
(2005)
Nat. Med.
, vol.11
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
Van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
Mesman, E.7
Dale, T.C.8
Schinkel, A.H.9
-
55
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
R.L. Juliano, and V. Ling A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants Biochim. Biophys. Acta 455 1976 152 162
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
56
-
-
78649678134
-
Multidrug resistance proteins (MRPs, ABCCs): Importance for pathophysiology and drug therapy
-
D. Keppler Multidrug resistance proteins (MRPs, ABCCs): importance for pathophysiology and drug therapy Handb. Exp. Pharmacol. 2011 299 323
-
(2011)
Handb. Exp. Pharmacol.
, pp. 299-323
-
-
Keppler, D.1
-
57
-
-
79953319793
-
Functional roles of Src and Fgr in ovarian carcinoma
-
H.S. Kim, H.D. Han, G.N. Armaiz-Pena, R.L. Stone, E.J. Nam, J.W. Lee, M.M. Shahzad, A.M. Nick, S.J. Lee, J.W. Roh, M. Nishimura, L.S. Mangala, J. Bottsford-Miller, G.E. Gallick, G. Lopez-Berestein, and A.K. Sood Functional roles of Src and Fgr in ovarian carcinoma Clin. Cancer Res. 17 2011 1713 1721
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 1713-1721
-
-
Kim, H.S.1
Han, H.D.2
Armaiz-Pena, G.N.3
Stone, R.L.4
Nam, E.J.5
Lee, J.W.6
Shahzad, M.M.7
Nick, A.M.8
Lee, S.J.9
Roh, J.W.10
Nishimura, M.11
Mangala, L.S.12
Bottsford-Miller, J.13
Gallick, G.E.14
Lopez-Berestein, G.15
Sood, A.K.16
-
58
-
-
24344480438
-
Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues
-
J.F. Klement, Y. Matsuzaki, Q.J. Jiang, J. Terlizzi, H.Y. Choi, N. Fujimoto, K. Li, L. Pulkkinen, D.E. Birk, J.P. Sundberg, and J. Uitto Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues Mol. Cell. Biol. 25 2005 8299 8310
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 8299-8310
-
-
Klement, J.F.1
Matsuzaki, Y.2
Jiang, Q.J.3
Terlizzi, J.4
Choi, H.Y.5
Fujimoto, N.6
Li, K.7
Pulkkinen, L.8
Birk, D.E.9
Sundberg, J.P.10
Uitto, J.11
-
59
-
-
0031027531
-
Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R))
-
R.J. Kowalski, P. Giannakakou, and E. Hamel Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)) J. Biol. Chem. 272 1997 2534 2541
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2534-2541
-
-
Kowalski, R.J.1
Giannakakou, P.2
Hamel, E.3
-
60
-
-
84856528076
-
Transportomics: Screening for substrates of ABC transporters in body fluids using vesicular transport assays
-
P. Krumpochova, S. Sapthu, J.F. Brouwers, M. de Haas, R. de Vos, P. Borst, K. van de, and Wetering Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays FASEB J. 26 2012 738 747
-
(2012)
FASEB J.
, vol.26
, pp. 738-747
-
-
Krumpochova, P.1
Sapthu, S.2
Brouwers, J.F.3
De Haas, M.4
De Vos, R.5
Borst, P.6
Van De, K.7
Wetering8
-
61
-
-
4344632950
-
Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
-
M. Leggas, M. Adachi, G.L. Scheffer, D. Sun, P. Wielinga, G. Du, K.E. Mercer, Y. Zhuang, J.C. Panetta, B. Johnston, R.J. Scheper, C.F. Stewart, and J.D. Schuetz Mrp4 confers resistance to topotecan and protects the brain from chemotherapy Mol. Cell. Biol. 24 2004 7612 7621
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7612-7621
-
-
Leggas, M.1
Adachi, M.2
Scheffer, G.L.3
Sun, D.4
Wielinga, P.5
Du, G.6
Mercer, K.E.7
Zhuang, Y.8
Panetta, J.C.9
Johnston, B.10
Scheper, R.J.11
Stewart, C.F.12
Schuetz, J.D.13
-
62
-
-
0033179095
-
Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: A Southwest Oncology Group Study
-
C.P. Leith, K.J. Kopecky, I.M. Chen, L. Eijdems, M.L. Slovak, T.S. McConnell, D.R. Head, J. Weick, M.R. Grever, F.R. Appelbaum, and C.L. Willman Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study Blood 94 1999 1086 1099
-
(1999)
Blood
, vol.94
, pp. 1086-1099
-
-
Leith, C.P.1
Kopecky, K.J.2
Chen, I.M.3
Eijdems, L.4
Slovak, M.L.5
McConnell, T.S.6
Head, D.R.7
Weick, J.8
Grever, M.R.9
Appelbaum, F.R.10
Willman, C.L.11
-
63
-
-
77953363931
-
Association of expression of MRP1, BCRP, LRP and ERCC1 with outcome of patients with locally advanced non-small cell lung cancer who received neoadjuvant chemotherapy
-
J. Li, Z.N. Li, L.C. Yu, Q.L. Bao, J.R. Wu, S.B. Shi, and X.Q. Li Association of expression of MRP1, BCRP, LRP and ERCC1 with outcome of patients with locally advanced non-small cell lung cancer who received neoadjuvant chemotherapy Lung Cancer 69 2010 116 122
-
(2010)
Lung Cancer
, vol.69
, pp. 116-122
-
-
Li, J.1
Li, Z.N.2
Yu, L.C.3
Bao, Q.L.4
Wu, J.R.5
Shi, S.B.6
Li, X.Q.7
-
64
-
-
76649129015
-
Expression of MRP1, BCRP, LRP and ERCC1 as prognostic factors in non-small cell lung cancer patients receiving postoperative cisplatin-based chemotherapy
-
X.Q. Li, J. Li, S.B. Shi, P. Chen, L.C. Yu, and Q.L. Bao Expression of MRP1, BCRP, LRP and ERCC1 as prognostic factors in non-small cell lung cancer patients receiving postoperative cisplatin-based chemotherapy Int. J. Biol. Markers 24 2009 230 237
-
(2009)
Int. J. Biol. Markers
, vol.24
, pp. 230-237
-
-
Li, X.Q.1
Li, J.2
Shi, S.B.3
Chen, P.4
Yu, L.C.5
Bao, Q.L.6
-
65
-
-
37349001082
-
Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response
-
Z.P. Lin, Y.L. Zhu, D.R. Johnson, K.P. Rice, T. Nottoli, B.C. Hains, J. McGrath, S.G. Waxman, and A.C. Sartorelli Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response Mol. Pharmacol. 73 2008 243 251
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 243-251
-
-
Lin, Z.P.1
Zhu, Y.L.2
Johnson, D.R.3
Rice, K.P.4
Nottoli, T.5
Hains, B.C.6
McGrath, J.7
Waxman, S.G.8
Sartorelli, A.C.9
-
66
-
-
80052252850
-
Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1
-
D. Liu, L. Ji, X. Tong, B. Pan, J.Y. Han, Y. Huang, Y.E. Chen, S. Pennathur, Y. Zhang, and L. Zheng Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1 Am. J. Physiol.: Cell Physiol. 301 2011 C739 C748
-
(2011)
Am. J. Physiol.: Cell Physiol.
, vol.301
, pp. C739-C748
-
-
Liu, D.1
Ji, L.2
Tong, X.3
Pan, B.4
Han, J.Y.5
Huang, Y.6
Chen, Y.E.7
Pennathur, S.8
Zhang, Y.9
Zheng, L.10
-
67
-
-
0030009305
-
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport
-
D.W. Loe, K.C. Almquist, R.G. Deeley, and S.P. Cole Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport J. Biol. Chem. 271 1996 9675 9682
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9675-9682
-
-
Loe, D.W.1
Almquist, K.C.2
Deeley, R.G.3
Cole, S.P.4
-
68
-
-
0032534064
-
Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
-
D.W. Loe, R.G. Deeley, and S.P. Cole Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione Cancer Res. 58 1998 5130 5136
-
(1998)
Cancer Res.
, vol.58
, pp. 5130-5136
-
-
Loe, D.W.1
Deeley, R.G.2
Cole, S.P.3
-
69
-
-
0030665969
-
Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
-
A. Lorico, G. Rappa, R.A. Finch, D. Yang, R.A. Flavell, and A.C. Sartorelli Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione Cancer Res. 57 1997 5238 5242
-
(1997)
Cancer Res.
, vol.57
, pp. 5238-5242
-
-
Lorico, A.1
Rappa, G.2
Finch, R.A.3
Yang, D.4
Flavell, R.A.5
Sartorelli, A.C.6
-
70
-
-
22344432207
-
Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice
-
J.M. Maher, A.L. Slitt, N.J. Cherrington, X. Cheng, and C.D. Klaassen Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice Drug Metab. Dispos. 33 2005 947 955
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 947-955
-
-
Maher, J.M.1
Slitt, A.L.2
Cherrington, N.J.3
Cheng, X.4
Klaassen, C.D.5
-
71
-
-
0035870289
-
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues
-
M. Maliepaard, G.L. Scheffer, I.F. Faneyte, M.A. van Gastelen, A.C. Pijnenborg, A.H. Schinkel, M.J. van De Vijver, R.J. Scheper, and J.H. Schellens Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues Cancer Res. 61 2001 3458 3464
-
(2001)
Cancer Res.
, vol.61
, pp. 3458-3464
-
-
Maliepaard, M.1
Scheffer, G.L.2
Faneyte, I.F.3
Van Gastelen, M.A.4
Pijnenborg, A.C.5
Schinkel, A.H.6
Van De Vijver, M.J.7
Scheper, R.J.8
Schellens, J.H.9
-
72
-
-
84922002485
-
Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport - An update
-
Q. Mao, and J.D. Unadkat Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport - an update AAPS J. 17 2015 65 82
-
(2015)
AAPS J.
, vol.17
, pp. 65-82
-
-
Mao, Q.1
Unadkat, J.D.2
-
73
-
-
17844365262
-
The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin
-
G. Merino, J.W. Jonker, E. Wagenaar, A.E. van Herwaarden, and A.H. Schinkel The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin Mol. Pharmacol. 67 2005 1758 1764
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 1758-1764
-
-
Merino, G.1
Jonker, J.W.2
Wagenaar, E.3
Van Herwaarden, A.E.4
Schinkel, A.H.5
-
74
-
-
78649648616
-
In vitro and in vivo evidence for the importance of breast cancer resistance protein transporters (BCRP/MXR/ABCP/ABCG2)
-
M.F. Fromm, R.B. Kim, Springer Berlin
-
H.E. Meyer zu Schwabedissen, and H.K. Kroemer In vitro and in vivo evidence for the importance of breast cancer resistance protein transporters (BCRP/MXR/ABCP/ABCG2) M.F. Fromm, R.B. Kim, Drug Transporters 2011 Springer Berlin 325 371
-
(2011)
Drug Transporters
, pp. 325-371
-
-
Meyer Zu Schwabedissen, H.E.1
Kroemer, H.K.2
-
75
-
-
0041668155
-
The role of P-glycoprotein in intestinal tumorigenesis: Disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice
-
Y. Mochida, K. Taguchi, S. Taniguchi, M. Tsuneyoshi, H. Kuwano, T. Tsuzuki, M. Kuwano, and M. Wada The role of P-glycoprotein in intestinal tumorigenesis: disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice Carcinogenesis 24 2003 1219 1224
-
(2003)
Carcinogenesis
, vol.24
, pp. 1219-1224
-
-
Mochida, Y.1
Taguchi, K.2
Taniguchi, S.3
Tsuneyoshi, M.4
Kuwano, H.5
Tsuzuki, T.6
Kuwano, M.7
Wada, M.8
-
76
-
-
84859216598
-
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
-
J.J. Molenaar, J. Koster, D.A. Zwijnenburg, P. van Sluis, L.J. Valentijn, I. van der Ploeg, M. Hamdi, J. van Nes, B.A. Westerman, J. van Arkel, M.E. Ebus, F. Haneveld, A. Lakeman, L. Schild, P. Molenaar, P. Stroeken, M.M. van Noesel, I. Ora, E.E. Santo, H.N. Caron, E.M. Westerhout, and R. Versteeg Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes Nature 483 2012 589 593
-
(2012)
Nature
, vol.483
, pp. 589-593
-
-
Molenaar, J.J.1
Koster, J.2
Zwijnenburg, D.A.3
Van Sluis, P.4
Valentijn, L.J.5
Van Der Ploeg, I.6
Hamdi, M.7
Van Nes, J.8
Westerman, B.A.9
Van Arkel, J.10
Ebus, M.E.11
Haneveld, F.12
Lakeman, A.13
Schild, L.14
Molenaar, P.15
Stroeken, P.16
Van Noesel, M.M.17
Ora, I.18
Santo, E.E.19
Caron, H.N.20
Westerhout, E.M.21
Versteeg, R.22
more..
-
77
-
-
0344390884
-
A PDZ-interacting domain in CFTR is an apical membrane polarization signal
-
B.D. Moyer, J. Denton, K.H. Karlson, D. Reynolds, S. Wang, J.E. Mickle, M. Milewski, G.R. Cutting, W.B. Guggino, M. Li, and B.A. Stanton A PDZ-interacting domain in CFTR is an apical membrane polarization signal J. Clin. Invest. 104 1999 1353 1361
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1353-1361
-
-
Moyer, B.D.1
Denton, J.2
Karlson, K.H.3
Reynolds, D.4
Wang, S.5
Mickle, J.E.6
Milewski, M.7
Cutting, G.R.8
Guggino, W.B.9
Li, M.10
Stanton, B.A.11
-
78
-
-
84858002750
-
Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
-
K. Natarajan, Y. Xie, M.R. Baer, and D.D. Ross Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance Biochem. Pharmacol. 83 2012 1084 1103
-
(2012)
Biochem. Pharmacol.
, vol.83
, pp. 1084-1103
-
-
Natarajan, K.1
Xie, Y.2
Baer, M.R.3
Ross, D.D.4
-
79
-
-
33645104459
-
Altered hepatobiliary disposition of 5 (and 6)-carboxy-2′,7′-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice
-
K. Nezasa, X. Tian, M.J. Zamek-Gliszczynski, N.J. Patel, T.J. Raub, and K.L. Brouwer Altered hepatobiliary disposition of 5 (and 6)-carboxy-2′,7′-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice Drug Metab. Dispos. 34 2006 718 723
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 718-723
-
-
Nezasa, K.1
Tian, X.2
Zamek-Gliszczynski, M.J.3
Patel, N.J.4
Raub, T.J.5
Brouwer, K.L.6
-
80
-
-
84925489354
-
Statin-induced decrease in ATP-binding cassette transporter A1 expression via microRNA33 induction may counteract cholesterol efflux to high-density lipoprotein
-
E.J. Niesor, G.G. Schwartz, A. Perez, A. Stauffer, A. Durrwell, G. Bucklar-Suchankova, R. Benghozi, M. Abt, and D. Kallend Statin-induced decrease in ATP-binding cassette transporter A1 expression via microRNA33 induction may counteract cholesterol efflux to high-density lipoprotein Cardiovasc. Drugs Ther. 29 2015 7 14
-
(2015)
Cardiovasc. Drugs Ther.
, vol.29
, pp. 7-14
-
-
Niesor, E.J.1
Schwartz, G.G.2
Perez, A.3
Stauffer, A.4
Durrwell, A.5
Bucklar-Suchankova, G.6
Benghozi, R.7
Abt, M.8
Kallend, D.9
-
81
-
-
84925285641
-
What do drug transporters really do?
-
S.K. Nigam What do drug transporters really do? Nat. Rev. Drug Discov. 14 2015 29 44
-
(2015)
Nat. Rev. Drug Discov.
, vol.14
, pp. 29-44
-
-
Nigam, S.K.1
-
82
-
-
84867419830
-
Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression
-
S. Nobili, I. Landini, T. Mazzei, and E. Mini Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression Med. Res. Rev. 32 2012 1220 1262
-
(2012)
Med. Res. Rev.
, vol.32
, pp. 1220-1262
-
-
Nobili, S.1
Landini, I.2
Mazzei, T.3
Mini, E.4
-
83
-
-
27644591577
-
Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1)
-
B.H. Norman, P.A. Lander, J.M. Gruber, J.S. Kroin, J.D. Cohen, L.N. Jungheim, J.J. Starling, K.L. Law, T.D. Self, L.B. Tabas, D.C. Williams, D.C. Paul, and A.H. Dantzig Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1) Bioorg. Med. Chem. Lett. 15 2005 5526 5530
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 5526-5530
-
-
Norman, B.H.1
Lander, P.A.2
Gruber, J.M.3
Kroin, J.S.4
Cohen, J.D.5
Jungheim, L.N.6
Starling, J.J.7
Law, K.L.8
Self, T.D.9
Tabas, L.B.10
Williams, D.C.11
Paul, D.C.12
Dantzig, A.H.13
-
84
-
-
0030031845
-
Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma
-
M.D. Norris, S.B. Bordow, G.M. Marshall, P.S. Haber, S.L. Cohn, and M. Haber Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma N. Engl. J. Med. 334 1996 231 238
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 231-238
-
-
Norris, M.D.1
Bordow, S.B.2
Marshall, G.M.3
Haber, P.S.4
Cohn, S.L.5
Haber, M.6
-
85
-
-
18044375868
-
Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro
-
M.D. Norris, J. Smith, K. Tanabe, P. Tobin, C. Flemming, G.L. Scheffer, P. Wielinga, S.L. Cohn, W.B. London, G.M. Marshall, J.D. Allen, and M. Haber Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro Mol. Cancer Ther. 4 2005 547 553
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 547-553
-
-
Norris, M.D.1
Smith, J.2
Tanabe, K.3
Tobin, P.4
Flemming, C.5
Scheffer, G.L.6
Wielinga, P.7
Cohn, S.L.8
London, W.B.9
Marshall, G.M.10
Allen, J.D.11
Haber, M.12
-
86
-
-
84954156733
-
Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization
-
J.E. Obreque-Balboa, Q. Sun, G. Bernhardt, B. Konig, and A. Buschauer Flavonoid derivatives as selective ABCC1 modulators: synthesis and functional characterization Eur. J. Med. Chem. 109 2016 124 133
-
(2016)
Eur. J. Med. Chem.
, vol.109
, pp. 124-133
-
-
Obreque-Balboa, J.E.1
Sun, Q.2
Bernhardt, G.3
Konig, B.4
Buschauer, A.5
-
87
-
-
64249164802
-
Hematopoietic stem cell differentiation affects expression and function of MRP4 (ABCC4), a transport protein for signaling molecules and drugs
-
L. Oevermann, J. Scheitz, K. Starke, K. Kock, T. Kiefer, G. Dolken, J. Niessen, A. Greinacher, W. Siegmund, M. Zygmunt, H.K. Kroemer, G. Jedlitschky, and C.A. Ritter Hematopoietic stem cell differentiation affects expression and function of MRP4 (ABCC4), a transport protein for signaling molecules and drugs Int. J. Cancer 124 2009 2303 2311
-
(2009)
Int. J. Cancer
, vol.124
, pp. 2303-2311
-
-
Oevermann, L.1
Scheitz, J.2
Starke, K.3
Kock, K.4
Kiefer, T.5
Dolken, G.6
Niessen, J.7
Greinacher, A.8
Siegmund, W.9
Zygmunt, M.10
Kroemer, H.K.11
Jedlitschky, G.12
Ritter, C.A.13
-
88
-
-
44949142967
-
Design, synthesis, and biological evaluation of new-generation taxoids
-
I. Ojima, J. Chen, L. Sun, C.P. Borella, T. Wang, M.L. Miller, S. Lin, X. Geng, L. Kuznetsova, C. Qu, D. Gallager, X. Zhao, I. Zanardi, S. Xia, S.B. Horwitz, J. Mallen-St Clair, J.L. Guerriero, D. Bar-Sagi, J.M. Veith, P. Pera, and R.J. Bernacki Design, synthesis, and biological evaluation of new-generation taxoids J. Med. Chem. 51 2008 3203 3221
-
(2008)
J. Med. Chem.
, vol.51
, pp. 3203-3221
-
-
Ojima, I.1
Chen, J.2
Sun, L.3
Borella, C.P.4
Wang, T.5
Miller, M.L.6
Lin, S.7
Geng, X.8
Kuznetsova, L.9
Qu, C.10
Gallager, D.11
Zhao, X.12
Zanardi, I.13
Xia, S.14
Horwitz, S.B.15
Mallen-St Clair, J.16
Guerriero, J.L.17
Bar-Sagi, D.18
Veith, J.M.19
Pera, P.20
Bernacki, R.J.21
more..
-
89
-
-
21744431708
-
Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1)
-
L. Payen, M. Gao, C. Westlake, A. Theis, S.P. Cole, and R.G. Deeley Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1) Mol. Pharmacol. 67 2005 1944 1953
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 1944-1953
-
-
Payen, L.1
Gao, M.2
Westlake, C.3
Theis, A.4
Cole, S.P.5
Deeley, R.G.6
-
90
-
-
0035900820
-
MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells
-
A.E. Peaston, M. Gardaneh, A.V. Franco, J.E. Hocker, K.M. Murphy, M.L. Farnsworth, D.R. Catchpoole, M. Haber, M.D. Norris, R.B. Lock, and G.M. Marshall MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells Br. J. Cancer 85 2001 1564 1571
-
(2001)
Br. J. Cancer
, vol.85
, pp. 1564-1571
-
-
Peaston, A.E.1
Gardaneh, M.2
Franco, A.V.3
Hocker, J.E.4
Murphy, K.M.5
Farnsworth, M.L.6
Catchpoole, D.R.7
Haber, M.8
Norris, M.D.9
Lock, R.B.10
Marshall, G.M.11
-
91
-
-
29344440700
-
Expression of multidrug resistance-associated proteins predicts prognosis in childhood and adult acute lymphoblastic leukemia
-
S.L. Plasschaert, E.S. de Bont, M. Boezen, D.M. vander Kolk, S.M. Daenen, K.N. Faber, W.A. Kamps, E.G. de Vries, and E. Vellenga Expression of multidrug resistance-associated proteins predicts prognosis in childhood and adult acute lymphoblastic leukemia Clin. Cancer Res. 11 2005 8661 8668
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 8661-8668
-
-
Plasschaert, S.L.1
De Bont, E.S.2
Boezen, M.3
Vander Kolk, D.M.4
Daenen, S.M.5
Faber, K.N.6
Kamps, W.A.7
De Vries, E.G.8
Vellenga, E.9
-
92
-
-
77953515718
-
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells
-
A. Porro, M. Haber, D. Diolaiti, N. Iraci, M. Henderson, S. Gherardi, E. Valli, M.A. Munoz, C. Xue, C. Flemming, M. Schwab, J.H. Wong, G.M. Marshall, G. Della Valle, M.D. Norris, and G. Perini Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells J. Biol. Chem. 285 2010 19532 19543
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 19532-19543
-
-
Porro, A.1
Haber, M.2
Diolaiti, D.3
Iraci, N.4
Henderson, M.5
Gherardi, S.6
Valli, E.7
Munoz, M.A.8
Xue, C.9
Flemming, C.10
Schwab, M.11
Wong, J.H.12
Marshall, G.M.13
Della Valle, G.14
Norris, M.D.15
Perini, G.16
-
93
-
-
13444291906
-
5-(2-Aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance
-
A.L. Ruchelman, P.J. Houghton, N. Zhou, A. Liu, L.F. Liu, and E.J. LaVoie 5-(2-Aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance J. Med. Chem. 48 2005 792 804
-
(2005)
J. Med. Chem.
, vol.48
, pp. 792-804
-
-
Ruchelman, A.L.1
Houghton, P.J.2
Zhou, N.3
Liu, A.4
Liu, L.F.5
LaVoie, E.J.6
-
94
-
-
0032813660
-
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
-
S. Rust, M. Rosier, H. Funke, J. Real, Z. Amoura, J.C. Piette, J.F. Deleuze, H.B. Brewer, N. Duverger, P. Denefle, and G. Assmann Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1 Nat. Genet. 22 1999 352 355
-
(1999)
Nat. Genet.
, vol.22
, pp. 352-355
-
-
Rust, S.1
Rosier, M.2
Funke, H.3
Real, J.4
Amoura, Z.5
Piette, J.C.6
Deleuze, J.F.7
Brewer, H.B.8
Duverger, N.9
Denefle, P.10
Assmann, G.11
-
95
-
-
84900314611
-
CRISPR-Cas systems for editing, regulating and targeting genomes
-
J.D. Sander, and J.K. Joung CRISPR-Cas systems for editing, regulating and targeting genomes Nat. Biotechnol. 32 2014 347 355
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 347-355
-
-
Sander, J.D.1
Joung, J.K.2
-
96
-
-
13444252391
-
MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia
-
M. Schaich, S. Soucek, C. Thiede, G. Ehninger, and T. Illmer MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia Br. J. Haematol. 128 2005 324 332
-
(2005)
Br. J. Haematol.
, vol.128
, pp. 324-332
-
-
Schaich, M.1
Soucek, S.2
Thiede, C.3
Ehninger, G.4
Illmer, T.5
-
97
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
-
A.H. Schinkel, U. Mayer, E. Wagenaar, C.A. Mol, L. van Deemter, J.J. Smit, M.A. van der Valk, A.C. Voordouw, H. Spits, O. van Tellingen, J.M. Zijlmans, W.E. Fibbe, and P. Borst Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins Proc. Natl. Acad. Sci. U. S. A. 94 1997 4028 4033
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.H.1
Mayer, U.2
Wagenaar, E.3
Mol, C.A.4
Van Deemter, L.5
Smit, J.J.6
Van Der Valk, M.A.7
Voordouw, A.C.8
Spits, H.9
Van Tellingen, O.10
Zijlmans, J.M.11
Fibbe, W.E.12
Borst, P.13
-
98
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
A.H. Schinkel, J.J. Smit, O. van Tellingen, J.H. Beijnen, E. Wagenaar, L. van Deemter, C.A. Mol, M.A. van der Valk, E.C. Robanus-Maandag, H.P. te Riele, and et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs Cell 77 1994 491 502
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.10
-
99
-
-
0022388606
-
Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
-
R.C. Seeger, G.M. Brodeur, H. Sather, A. Dalton, S.E. Siegel, K.Y. Wong, and D. Hammond Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas N. Engl. J. Med. 313 1985 1111 1116
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 1111-1116
-
-
Seeger, R.C.1
Brodeur, G.M.2
Sather, H.3
Dalton, A.4
Siegel, S.E.5
Wong, K.Y.6
Hammond, D.7
-
100
-
-
77957154686
-
High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism
-
Y. Sekine, S.J. Demosky, J.A. Stonik, Y. Furuya, H. Koike, K. Suzuki, and A.T. Remaley High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism Mol. Cancer Res. 8 2010 1284 1294
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 1284-1294
-
-
Sekine, Y.1
Demosky, S.J.2
Stonik, J.A.3
Furuya, Y.4
Koike, H.5
Suzuki, K.6
Remaley, A.T.7
-
101
-
-
84860689257
-
Drug resistance: Still a daunting challenge to the successful treatment of AML
-
B.C. Shaffer, J.P. Gillet, C. Patel, M.R. Baer, S.E. Bates, and M.M. Gottesman Drug resistance: still a daunting challenge to the successful treatment of AML Drug Resist. Updates 15 2012 62 69
-
(2012)
Drug Resist. Updates
, vol.15
, pp. 62-69
-
-
Shaffer, B.C.1
Gillet, J.P.2
Patel, C.3
Baer, M.R.4
Bates, S.E.5
Gottesman, M.M.6
-
102
-
-
80052490064
-
Mammalian multidrug-resistance proteins (MRPs)
-
A.J. Slot, S.V. Molinski, and S.P. Cole Mammalian multidrug-resistance proteins (MRPs) Essays Biochem. 50 2011 179 207
-
(2011)
Essays Biochem.
, vol.50
, pp. 179-207
-
-
Slot, A.J.1
Molinski, S.V.2
Cole, S.P.3
-
103
-
-
84866922242
-
Anticancer activity of the cholesterol exporter ABCA1 gene
-
B. Smith, and H. Land Anticancer activity of the cholesterol exporter ABCA1 gene Cell Rep. 2 2012 580 590
-
(2012)
Cell Rep.
, vol.2
, pp. 580-590
-
-
Smith, B.1
Land, H.2
-
104
-
-
12644278301
-
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
A. Sparreboom, J. van Asperen, U. Mayer, A.H. Schinkel, J.W. Smit, D.K. Meijer, P. Borst, W.J. Nooijen, J.H. Beijnen, and O. van Tellingen Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine Proc. Natl. Acad. Sci. U. S. A. 94 1997 2031 2035
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 2031-2035
-
-
Sparreboom, A.1
Van Asperen, J.2
Mayer, U.3
Schinkel, A.H.4
Smit, J.W.5
Meijer, D.K.6
Borst, P.7
Nooijen, W.J.8
Beijnen, J.H.9
Van Tellingen, O.10
-
105
-
-
0041842584
-
Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate
-
M. Stark, L. Rothem, G. Jansen, G.L. Scheffer, I.D. Goldman, and Y.G. Assaraf Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate Mol. Pharmacol. 64 2003 220 227
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 220-227
-
-
Stark, M.1
Rothem, L.2
Jansen, G.3
Scheffer, G.L.4
Goldman, I.D.5
Assaraf, Y.G.6
-
106
-
-
0030775395
-
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells
-
B.D. Stride, C.E. Grant, D.W. Loe, D.R. Hipfner, S.P. Cole, and R.G. Deeley Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells Mol. Pharmacol. 52 1997 344 353
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 344-353
-
-
Stride, B.D.1
Grant, C.E.2
Loe, D.W.3
Hipfner, D.R.4
Cole, S.P.5
Deeley, R.G.6
-
107
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
G. Szakacs, J.K. Paterson, J.A. Ludwig, C. Booth-Genthe, and M.M. Gottesman Targeting multidrug resistance in cancer Nat. Rev. Drug Discov. 5 2006 219 234
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
108
-
-
1542320076
-
Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol
-
C. Tang, A.M. Vaughan, and J.F. Oram Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol J. Biol. Chem. 279 2004 7622 7628
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7622-7628
-
-
Tang, C.1
Vaughan, A.M.2
Oram, J.F.3
-
110
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
F. Thiebaut, T. Tsuruo, H. Hamada, M.M. Gottesman, I. Pastan, and M.C. Willingham Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues Proc. Natl. Acad. Sci. U. S. A. 84 1987 7735 7738
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
111
-
-
33751104270
-
Multidrug resistance in small cell lung cancer: Expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease
-
N. Triller, P. Korosec, I. Kern, M. Kosnik, and A. Debeljak Multidrug resistance in small cell lung cancer: expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease Lung Cancer 54 2006 235 240
-
(2006)
Lung Cancer
, vol.54
, pp. 235-240
-
-
Triller, N.1
Korosec, P.2
Kern, I.3
Kosnik, M.4
Debeljak, A.5
-
112
-
-
0030920342
-
Multidrug resistance in breast cancer: A meta-analysis of MDR1/gp170 expression and its possible functional significance
-
B.J. Trock, F. Leonessa, and R. Clarke Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance J. Natl. Cancer Inst. 89 1997 917 931
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 917-931
-
-
Trock, B.J.1
Leonessa, F.2
Clarke, R.3
-
113
-
-
0008632564
-
Expression of a full-length cDNA for the human "mDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine
-
K. Ueda, C. Cardarelli, M.M. Gottesman, and I. Pastan Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine Proc. Natl. Acad. Sci. U. S. A. 84 1987 3004 3008
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 3004-3008
-
-
Ueda, K.1
Cardarelli, C.2
Gottesman, M.M.3
Pastan, I.4
-
114
-
-
70350733785
-
ABC drug transporters and immunity: Novel therapeutic targets in autoimmunity and cancer
-
R. van de Ven, R. Oerlemans, J.W. van der Heijden, G.L. Scheffer, T.D. de Gruijl, G. Jansen, and R.J. Scheper ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer J. Leukoc. Biol. 86 2009 1075 1087
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 1075-1087
-
-
Van De Ven, R.1
Oerlemans, R.2
Van Der Heijden, J.W.3
Scheffer, G.L.4
De Gruijl, T.D.5
Jansen, G.6
Scheper, R.J.7
-
115
-
-
55249123453
-
A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration
-
R. van de Ven, G.L. Scheffer, A.W. Reurs, J.J. Lindenberg, R. Oerlemans, G. Jansen, J.P. Gillet, J.N. Glasgow, A. Pereboev, D.T. Curiel, R.J. Scheper, and T.D. de Gruijl A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration Blood 112 2008 2353 2359
-
(2008)
Blood
, vol.112
, pp. 2353-2359
-
-
Van De Ven, R.1
Scheffer, G.L.2
Reurs, A.W.3
Lindenberg, J.J.4
Oerlemans, R.5
Jansen, G.6
Gillet, J.P.7
Glasgow, J.N.8
Pereboev, A.9
Curiel, D.T.10
Scheper, R.J.11
De Gruijl, T.D.12
-
116
-
-
70350104791
-
Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo
-
K. van de Wetering, W. Feddema, J.B. Helms, J.F. Brouwers, and P. Borst Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo Gastroenterology 137 2009 1725 1735
-
(2009)
Gastroenterology
, vol.137
, pp. 1725-1735
-
-
Van De Wetering, K.1
Feddema, W.2
Helms, J.B.3
Brouwers, J.F.4
Borst, P.5
-
117
-
-
84868134869
-
ABCG2 functions as a general phytoestrogen sulfate transporter in vivo
-
K. van de Wetering, and S. Sapthu ABCG2 functions as a general phytoestrogen sulfate transporter in vivo FASEB J. 26 2012 4014 4024
-
(2012)
FASEB J.
, vol.26
, pp. 4014-4024
-
-
Van De Wetering, K.1
Sapthu, S.2
-
118
-
-
0141919551
-
The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
A.E. van Herwaarden, J.W. Jonker, E. Wagenaar, R.F. Brinkhuis, J.H. Schellens, J.H. Beijnen, and A.H. Schinkel The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Cancer Res. 63 2003 6447 6452
-
(2003)
Cancer Res.
, vol.63
, pp. 6447-6452
-
-
Van Herwaarden, A.E.1
Jonker, J.W.2
Wagenaar, E.3
Brinkhuis, R.F.4
Schellens, J.H.5
Beijnen, J.H.6
Schinkel, A.H.7
-
119
-
-
64749104937
-
ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation
-
A.M. Vaughan, C. Tang, and J.F. Oram ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation J. Lipid Res. 50 2009 285 292
-
(2009)
J. Lipid Res.
, vol.50
, pp. 285-292
-
-
Vaughan, A.M.1
Tang, C.2
Oram, J.F.3
-
120
-
-
34548364160
-
Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles
-
C. Vedhachalam, P.T. Duong, M. Nickel, D. Nguyen, P. Dhanasekaran, H. Saito, G.H. Rothblat, S. Lund-Katz, and M.C. Phillips Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles J. Biol. Chem. 282 2007 25123 25130
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 25123-25130
-
-
Vedhachalam, C.1
Duong, P.T.2
Nickel, M.3
Nguyen, D.4
Dhanasekaran, P.5
Saito, H.6
Rothblat, G.H.7
Lund-Katz, S.8
Phillips, M.C.9
-
121
-
-
33745236689
-
Carcinogen and anticancer drug transport by Mrp2 in vivo: Studies using Mrp2 (Abcc2) knockout mice
-
M.L. Vlaming, K. Mohrmann, E. Wagenaar, D.R. de Waart, R.P. Elferink, J.S. Lagas, O. van Tellingen, L.D. Vainchtein, H. Rosing, J.H. Beijnen, J.H. Schellens, and A.H. Schinkel Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice J. Pharmacol. Exp. Ther. 318 2006 319 327
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.318
, pp. 319-327
-
-
Vlaming, M.L.1
Mohrmann, K.2
Wagenaar, E.3
De Waart, D.R.4
Elferink, R.P.5
Lagas, J.S.6
Van Tellingen, O.7
Vainchtein, L.D.8
Rosing, H.9
Beijnen, J.H.10
Schellens, J.H.11
Schinkel, A.H.12
-
122
-
-
0030999641
-
Targeted expression of MYCN causes neuroblastoma in transgenic mice
-
W. Weiss, K. Aldape, G. Mohapatra, B. Feuerstein, and J. Bishop Targeted expression of MYCN causes neuroblastoma in transgenic mice EMBO J. 16 1997 2985 2995
-
(1997)
EMBO J.
, vol.16
, pp. 2985-2995
-
-
Weiss, W.1
Aldape, K.2
Mohapatra, G.3
Feuerstein, B.4
Bishop, J.5
-
123
-
-
0032812095
-
Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model
-
J.R. Wiener, K. Nakano, R.P. Kruzelock, C.D. Bucana, R.C. Bast Jr., and G.E. Gallick Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model Clin. Cancer Res. 5 1999 2164 2170
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2164-2170
-
-
Wiener, J.R.1
Nakano, K.2
Kruzelock, R.P.3
Bucana, C.D.4
Bast, R.C.5
Gallick, G.E.6
-
124
-
-
0037229627
-
Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers
-
J.R. Wiener, T.C. Windham, V.C. Estrella, N.U. Parikh, P.F. Thall, M.T. Deavers, R.C. Bast, G.B. Mills, and G.E. Gallick Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers Gynecol. Oncol. 88 2003 73 79
-
(2003)
Gynecol. Oncol.
, vol.88
, pp. 73-79
-
-
Wiener, J.R.1
Windham, T.C.2
Estrella, V.C.3
Parikh, N.U.4
Thall, P.F.5
Deavers, M.T.6
Bast, R.C.7
Mills, G.B.8
Gallick, G.E.9
-
125
-
-
0033975098
-
Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier
-
J. Wijnholds, E.C. deLange, G.L. Scheffer, D.J. van den Berg, C.A. Mol, M. van der Valk, A.H. Schinkel, R.J. Scheper, D.D. Breimer, and P. Borst Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier J. Clin. Invest. 105 2000 279 285
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 279-285
-
-
Wijnholds, J.1
DeLange, E.C.2
Scheffer, G.L.3
Van Den Berg, D.J.4
Mol, C.A.5
Van Der Valk, M.6
Schinkel, A.H.7
Scheper, R.J.8
Breimer, D.D.9
Borst, P.10
-
126
-
-
20244386956
-
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
-
J. Wijnholds, R. Evers, M.R. van Leusden, C.A. Mol, G.J. Zaman, U. Mayer, J.H. Beijnen, M. van der Valk, P. Krimpenfort, and P. Borst Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein Nat. Med. 3 1997 1275 1279
-
(1997)
Nat. Med.
, vol.3
, pp. 1275-1279
-
-
Wijnholds, J.1
Evers, R.2
Van Leusden, M.R.3
Mol, C.A.4
Zaman, G.J.5
Mayer, U.6
Beijnen, J.H.7
Van Der Valk, M.8
Krimpenfort, P.9
Borst, P.10
-
127
-
-
0032494133
-
Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage
-
J. Wijnholds, G.L. Scheffer, M. van der Valk, P. van der Valk, J.H. Beijnen, R.J. Scheper, and P. Borst Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage J. Exp. Med. 188 1998 797 808
-
(1998)
J. Exp. Med.
, vol.188
, pp. 797-808
-
-
Wijnholds, J.1
Scheffer, G.L.2
Van Der Valk, M.3
Van Der Valk, P.4
Beijnen, J.H.5
Scheper, R.J.6
Borst, P.7
-
128
-
-
84927130835
-
High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo
-
J. Xu, M. Yong, J. Li, X. Dong, T. Yu, X. Fu, and L. Hu High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo Oncol. Rep. 33 2015 2227 2234
-
(2015)
Oncol. Rep.
, vol.33
, pp. 2227-2234
-
-
Xu, J.1
Yong, M.2
Li, J.3
Dong, X.4
Yu, T.5
Fu, X.6
Hu, L.7
-
129
-
-
0037373889
-
Suppression of intestinal polyposis in Mdr1-deficient ApcMin/+ mice
-
T. Yamada, Y. Mori, R. Hayashi, M. Takada, Y. Ino, Y. Naishiro, T. Kondo, and S. Hirohashi Suppression of intestinal polyposis in Mdr1-deficient ApcMin/+ mice Cancer Res. 63 2003 895 901
-
(2003)
Cancer Res.
, vol.63
, pp. 895-901
-
-
Yamada, T.1
Mori, Y.2
Hayashi, R.3
Takada, M.4
Ino, Y.5
Naishiro, Y.6
Kondo, T.7
Hirohashi, S.8
-
130
-
-
34250769986
-
Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients
-
T. Yamagata, H. Kusuhara, M. Morishita, K. Takayama, H. Benameur, and Y. Sugiyama Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients Drug Metab. Dispos. 35 2007 1142 1148
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 1142-1148
-
-
Yamagata, T.1
Kusuhara, H.2
Morishita, M.3
Takayama, K.4
Benameur, H.5
Sugiyama, Y.6
-
131
-
-
0035119989
-
In vitro substrate identification studies for p-glycoprotein-mediated transport: Species difference and predictability of in vivo results
-
M. Yamazaki, W.E. Neway, T. Ohe, I. Chen, J.F. Rowe, J.H. Hochman, M. Chiba, and J.H. Lin In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results J. Pharmacol. Exp. Ther. 296 2001 723 735
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 723-735
-
-
Yamazaki, M.1
Neway, W.E.2
Ohe, T.3
Chen, I.4
Rowe, J.F.5
Hochman, J.H.6
Chiba, M.7
Lin, J.H.8
-
132
-
-
84878107592
-
Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: Why has it failed to provide clinical benefit?
-
M. Yu, A. Ocana, and I.F. Tannock Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: why has it failed to provide clinical benefit? Cancer Metastasis Rev. 32 2013 211 227
-
(2013)
Cancer Metastasis Rev.
, vol.32
, pp. 211-227
-
-
Yu, M.1
Ocana, A.2
Tannock, I.F.3
-
133
-
-
84866478690
-
Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol
-
S.A. Zander, A. Kersbergen, W. Sol, M. Gonggrijp, K. van de Wetering, J. Jonkers, P. Borst, and S. Rottenberg Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol Cancer Prev. Res. (Philadelphia, Pa) 5 2012 1053 1060
-
(2012)
Cancer Prev. Res. (Philadelphia, Pa)
, vol.5
, pp. 1053-1060
-
-
Zander, S.A.1
Kersbergen, A.2
Sol, W.3
Gonggrijp, M.4
Van De Wetering, K.5
Jonkers, J.6
Borst, P.7
Rottenberg, S.8
-
134
-
-
76749114340
-
Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase i inhibitor topotecan
-
S.A. Zander, A. Kersbergen, E. van der Burg, N. de Water, O. van Tellingen, S. Gunnarsdottir, J.E. Jaspers, M. Pajic, A.O. Nygren, J. Jonkers, P. Borst, and S. Rottenberg Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan Cancer Res. 70 2010 1700 1710
-
(2010)
Cancer Res.
, vol.70
, pp. 1700-1710
-
-
Zander, S.A.1
Kersbergen, A.2
Van Der Burg, E.3
De Water, N.4
Van Tellingen, O.5
Gunnarsdottir, S.6
Jaspers, J.E.7
Pajic, M.8
Nygren, A.O.9
Jonkers, J.10
Borst, P.11
Rottenberg, S.12
-
135
-
-
21044435938
-
Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception
-
N. Zelcer, K. van de Wetering, M. Hillebrand, E. Sarton, A. Kuil, P.R. Wielinga, T. Tephly, A. Dahan, J.H. Beijnen, and P. Borst Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception Proc. Natl. Acad. Sci. U. S. A. 102 2005 7274 7279
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 7274-7279
-
-
Zelcer, N.1
Van De Wetering, K.2
Hillebrand, M.3
Sarton, E.4
Kuil, A.5
Wielinga, P.R.6
Tephly, T.7
Dahan, A.8
Beijnen, J.H.9
Borst, P.10
-
136
-
-
81455158692
-
The ABCC4 gene is a promising target for pancreatic cancer therapy
-
Z. Zhang, J. Wang, B. Shen, C. Peng, and M. Zheng The ABCC4 gene is a promising target for pancreatic cancer therapy Gene 491 2012 194 199
-
(2012)
Gene
, vol.491
, pp. 194-199
-
-
Zhang, Z.1
Wang, J.2
Shen, B.3
Peng, C.4
Zheng, M.5
-
137
-
-
84858201901
-
The interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipids
-
G.J. Zhao, K. Yin, Y.C. Fu, and C.K. Tang The interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipids Mol. Med. (Cambridge, MA) 18 2012 149 158
-
(2012)
Mol. Med. (Cambridge, MA)
, vol.18
, pp. 149-158
-
-
Zhao, G.J.1
Yin, K.2
Fu, Y.C.3
Tang, C.K.4
-
138
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
S. Zhou, J.D. Schuetz, K.D. Bunting, A.M. Colapietro, J. Sampath, J.J. Morris, I. Lagutina, G.C. Grosveld, M. Osawa, H. Nakauchi, and B.P. Sorrentino The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype Nat. Med. 7 2001 1028 1034
-
(2001)
Nat. Med.
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
Lagutina, I.7
Grosveld, G.C.8
Osawa, M.9
Nakauchi, H.10
Sorrentino, B.P.11
|