메뉴 건너뛰기




Volumn 26, Issue , 2016, Pages 1-9

ABC transporters as mediators of drug resistance and contributors to cancer cell biology

Author keywords

Endogenous substrates; Multidrug resistance; Neuroblastoma; Ovarian cancer; Tumorigenesis

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; BREAST CANCER RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1;

EID: 84962207990     PISSN: 13687646     EISSN: 15322084     Source Type: Journal    
DOI: 10.1016/j.drup.2016.03.001     Document Type: Article
Times cited : (340)

References (138)
  • 1
    • 68449084682 scopus 로고    scopus 로고
    • MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development
    • G. Alam, H. Cui, H. Shi, L. Yang, J. Ding, L. Mao, W.A. Maltese, and H.F. Ding MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development Am. J. Pathol. 175 2009 856 866
    • (2009) Am. J. Pathol. , vol.175 , pp. 856-866
    • Alam, G.1    Cui, H.2    Shi, H.3    Yang, L.4    Ding, J.5    Mao, L.6    Maltese, W.A.7    Ding, H.F.8
  • 2
    • 33846678695 scopus 로고    scopus 로고
    • The ABCA subfamily - Gene and protein structures, functions and associated hereditary diseases
    • C. Albrecht, and E. Viturro The ABCA subfamily - gene and protein structures, functions and associated hereditary diseases Pflug. Arch. 453 2007 581 589
    • (2007) Pflug. Arch. , vol.453 , pp. 581-589
    • Albrecht, C.1    Viturro, E.2
  • 4
    • 84860669151 scopus 로고    scopus 로고
    • Targeting MDR in breast and lung cancer: Discriminating its potential importance from the failure of drug resistance reversal studies
    • L. Amiri-Kordestani, A. Basseville, K. Kurdziel, A.T. Fojo, and S.E. Bates Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies Drug Resist. Updates 15 2012 50 61
    • (2012) Drug Resist. Updates , vol.15 , pp. 50-61
    • Amiri-Kordestani, L.1    Basseville, A.2    Kurdziel, K.3    Fojo, A.T.4    Bates, S.E.5
  • 5
    • 0024538964 scopus 로고
    • Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype
    • Y.G. Assaraf, A. Molina, and R.T. Schimke Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype J. Natl. Cancer Inst. 81 1989 290 294
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 290-294
    • Assaraf, Y.G.1    Molina, A.2    Schimke, R.T.3
  • 6
    • 0024467350 scopus 로고
    • Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate
    • Y.G. Assaraf, A. Molina, and R.T. Schimke Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate J. Biol. Chem. 264 1989 18326 18334
    • (1989) J. Biol. Chem. , vol.264 , pp. 18326-18334
    • Assaraf, Y.G.1    Molina, A.2    Schimke, R.T.3
  • 10
    • 0030062653 scopus 로고    scopus 로고
    • Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity
    • M.J. Borgnia, G.D. Eytan, and Y.G. Assaraf Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity J. Biol. Chem. 271 1996 3163 3171
    • (1996) J. Biol. Chem. , vol.271 , pp. 3163-3171
    • Borgnia, M.J.1    Eytan, G.D.2    Assaraf, Y.G.3
  • 11
    • 66049093214 scopus 로고    scopus 로고
    • Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2
    • E.E. Bram, Y. Adar, N. Mesika, M. Sabisz, A. Skladanowski, and Y.G. Assaraf Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2 Mol. Pharmacol. 75 2009 1149 1159
    • (2009) Mol. Pharmacol. , vol.75 , pp. 1149-1159
    • Bram, E.E.1    Adar, Y.2    Mesika, N.3    Sabisz, M.4    Skladanowski, A.5    Assaraf, Y.G.6
  • 12
    • 72949085978 scopus 로고    scopus 로고
    • Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance
    • E.E. Bram, M. Stark, S. Raz, and Y.G. Assaraf Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance Neoplasia 11 2009 1359 1370
    • (2009) Neoplasia , vol.11 , pp. 1359-1370
    • Bram, E.E.1    Stark, M.2    Raz, S.3    Assaraf, Y.G.4
  • 13
    • 0035955452 scopus 로고    scopus 로고
    • Interaction between two adapter proteins, PAG and EBP50: A possible link between membrane rafts and actin cytoskeleton
    • N. Brdickova, T. Brdicka, L. Andera, J. Spicka, P. Angelisova, S.L. Milgram, and V. Horejsi Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton FEBS Lett. 507 2001 133 136
    • (2001) FEBS Lett. , vol.507 , pp. 133-136
    • Brdickova, N.1    Brdicka, T.2    Andera, L.3    Spicka, J.4    Angelisova, P.5    Milgram, S.L.6    Horejsi, V.7
  • 14
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • G.M. Brodeur, R.C. Seeger, M. Schwab, H.E. Varmus, and J.M. Bishop Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage Science 224 1984 1121 1124
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3    Varmus, H.E.4    Bishop, J.M.5
  • 16
    • 0037314795 scopus 로고    scopus 로고
    • RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response
    • H. Burger, J.A. Foekens, M.P. Look, M.E. Meijer-van Gelder, J.G. Klijn, E.A. Wiemer, G. Stoter, and K. Nooter RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response Clin. Cancer Res. 9 2003 827 836
    • (2003) Clin. Cancer Res. , vol.9 , pp. 827-836
    • Burger, H.1    Foekens, J.A.2    Look, M.P.3    Meijer Van Gelder, M.E.4    Klijn, J.G.5    Wiemer, E.A.6    Stoter, G.7    Nooter, K.8
  • 18
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
    • C.J. Chen, J.E. Chin, K. Ueda, D.P. Clark, I. Pastan, M.M. Gottesman, and I.B. Roninson Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells Cell 47 1986 381 389
    • (1986) Cell , vol.47 , pp. 381-389
    • Chen, C.J.1    Chin, J.E.2    Ueda, K.3    Clark, D.P.4    Pastan, I.5    Gottesman, M.M.6    Roninson, I.B.7
  • 19
    • 0032530533 scopus 로고    scopus 로고
    • Taxol resistance mediated by transfection of the liver-specific sister gene of P-glycoprotein
    • S. Childs, R.L. Yeh, D. Hui, and V. Ling Taxol resistance mediated by transfection of the liver-specific sister gene of P-glycoprotein Cancer Res. 58 1998 4160 4167
    • (1998) Cancer Res. , vol.58 , pp. 4160-4167
    • Childs, S.1    Yeh, R.L.2    Hui, D.3    Ling, V.4
  • 22
    • 33745897902 scopus 로고    scopus 로고
    • Transport of glutathione and glutathione conjugates by MRP1
    • S.P. Cole, and R.G. Deeley Transport of glutathione and glutathione conjugates by MRP1 Trends Pharmacol. Sci. 27 2006 438 446
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 438-446
    • Cole, S.P.1    Deeley, R.G.2
  • 23
    • 0037113346 scopus 로고    scopus 로고
    • Localisation of breast cancer resistance protein in microvessel endothelium of human brain
    • H.C. Cooray, C.G. Blackmore, L. Maskell, and M.A. Barrand Localisation of breast cancer resistance protein in microvessel endothelium of human brain Neuroreport 13 2002 2059 2063
    • (2002) Neuroreport , vol.13 , pp. 2059-2063
    • Cooray, H.C.1    Blackmore, C.G.2    Maskell, L.3    Barrand, M.A.4
  • 24
    • 84910084359 scopus 로고    scopus 로고
    • Multidrug resistance protein 4/ATP binding cassette transporter 4: A new potential therapeutic target for acute myeloid leukemia
    • S. Copsel, A. Bruzzone, M. May, J. Beyrath, V. Wargon, J. Cany, F.G. Russel, C. Shayo, and C. Davio Multidrug resistance protein 4/ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia Oncotarget 5 2014 9308 9321
    • (2014) Oncotarget , vol.5 , pp. 9308-9321
    • Copsel, S.1    Bruzzone, A.2    May, M.3    Beyrath, J.4    Wargon, V.5    Cany, J.6    Russel, F.G.7    Shayo, C.8    Davio, C.9
  • 25
    • 79953191123 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation
    • S. Copsel, C. Garcia, F. Diez, M. Vermeulem, A. Baldi, L.G. Bianciotti, F.G. Russel, C. Shayo, and C. Davio Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation J. Biol. Chem. 286 2011 6979 6988
    • (2011) J. Biol. Chem. , vol.286 , pp. 6979-6988
    • Copsel, S.1    Garcia, C.2    Diez, F.3    Vermeulem, M.4    Baldi, A.5    Bianciotti, L.G.6    Russel, F.G.7    Shayo, C.8    Davio, C.9
  • 27
    • 0024544045 scopus 로고
    • The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
    • J.M. Croop, M. Raymond, D. Haber, A. Devault, R.J. Arceci, P. Gros, and D.E. Housman The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues Mol. Cell. Biol. 9 1989 1346 1350
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1346-1350
    • Croop, J.M.1    Raymond, M.2    Haber, D.3    Devault, A.4    Arceci, R.J.5    Gros, P.6    Housman, D.E.7
  • 29
    • 30144435485 scopus 로고    scopus 로고
    • The genetics of ATP-binding cassette transporters
    • M. Dean The genetics of ATP-binding cassette transporters Methods Enzymol. 400 2005 409 429
    • (2005) Methods Enzymol. , vol.400 , pp. 409-429
    • Dean, M.1
  • 30
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • M. Dean, T. Fojo, and S. Bates Tumour stem cells and drug resistance Nat. Rev. Cancer 5 2005 275 284
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 31
    • 31844455959 scopus 로고    scopus 로고
    • Substrate recognition and transport by multidrug resistance protein 1 (ABCC1)
    • R.G. Deeley, and S.P. Cole Substrate recognition and transport by multidrug resistance protein 1 (ABCC1) FEBS Lett. 580 2006 1103 1111
    • (2006) FEBS Lett. , vol.580 , pp. 1103-1111
    • Deeley, R.G.1    Cole, S.P.2
  • 33
    • 70350351085 scopus 로고    scopus 로고
    • Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells
    • W. Dong, S. Vuletic, and J.J. Albers Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells J. Lipid Res. 50 2009 2095 2102
    • (2009) J. Lipid Res. , vol.50 , pp. 2095-2102
    • Dong, W.1    Vuletic, S.2    Albers, J.J.3
  • 35
    • 0028020549 scopus 로고
    • Transport of polypeptide ionophores into proteoliposomes reconstituted with rat liver P-glycoprotein
    • G.D. Eytan, M.J. Borgnia, R. Regev, and Y.G. Assaraf Transport of polypeptide ionophores into proteoliposomes reconstituted with rat liver P-glycoprotein J. Biol. Chem. 269 1994 26058 26065
    • (1994) J. Biol. Chem. , vol.269 , pp. 26058-26065
    • Eytan, G.D.1    Borgnia, M.J.2    Regev, R.3    Assaraf, Y.G.4
  • 39
    • 0023019651 scopus 로고
    • Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
    • J.H. Gerlach, J.A. Endicott, P.F. Juranka, G. Henderson, F. Sarangi, K.L. Deuchars, and V. Ling Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance Nature 324 1986 485 489
    • (1986) Nature , vol.324 , pp. 485-489
    • Gerlach, J.H.1    Endicott, J.A.2    Juranka, P.F.3    Henderson, G.4    Sarangi, F.5    Deuchars, K.L.6    Ling, V.7
  • 42
    • 0022993652 scopus 로고
    • Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
    • P. Gros, J. Croop, and D. Housman Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins Cell 47 1986 371 380
    • (1986) Cell , vol.47 , pp. 371-380
    • Gros, P.1    Croop, J.2    Housman, D.3
  • 43
    • 33645747683 scopus 로고    scopus 로고
    • Association of high-level MRP1 expression with poor clinical outcome in a large prospective study of primary neuroblastoma
    • M. Haber, J. Smith, S.B. Bordow, C. Flemming, S.L. Cohn, W.B. London, G.M. Marshall, and M.D. Norris Association of high-level MRP1 expression with poor clinical outcome in a large prospective study of primary neuroblastoma J. Clin. Oncol. 24 2006 1546 1553
    • (2006) J. Clin. Oncol. , vol.24 , pp. 1546-1553
    • Haber, M.1    Smith, J.2    Bordow, S.B.3    Flemming, C.4    Cohn, S.L.5    London, W.B.6    Marshall, G.M.7    Norris, M.D.8
  • 46
  • 51
    • 59149089885 scopus 로고    scopus 로고
    • The role of ATP binding cassette transporters in tissue defense and organ regeneration
    • M. Huls, F.G. Russel, and R. Masereeuw The role of ATP binding cassette transporters in tissue defense and organ regeneration J. Pharmacol. Exp. Ther. 328 2009 3 9
    • (2009) J. Pharmacol. Exp. Ther. , vol.328 , pp. 3-9
    • Huls, M.1    Russel, F.G.2    Masereeuw, R.3
  • 55
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • R.L. Juliano, and V. Ling A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants Biochim. Biophys. Acta 455 1976 152 162
    • (1976) Biochim. Biophys. Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 56
    • 78649678134 scopus 로고    scopus 로고
    • Multidrug resistance proteins (MRPs, ABCCs): Importance for pathophysiology and drug therapy
    • D. Keppler Multidrug resistance proteins (MRPs, ABCCs): importance for pathophysiology and drug therapy Handb. Exp. Pharmacol. 2011 299 323
    • (2011) Handb. Exp. Pharmacol. , pp. 299-323
    • Keppler, D.1
  • 59
    • 0031027531 scopus 로고    scopus 로고
    • Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R))
    • R.J. Kowalski, P. Giannakakou, and E. Hamel Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)) J. Biol. Chem. 272 1997 2534 2541
    • (1997) J. Biol. Chem. , vol.272 , pp. 2534-2541
    • Kowalski, R.J.1    Giannakakou, P.2    Hamel, E.3
  • 60
    • 84856528076 scopus 로고    scopus 로고
    • Transportomics: Screening for substrates of ABC transporters in body fluids using vesicular transport assays
    • P. Krumpochova, S. Sapthu, J.F. Brouwers, M. de Haas, R. de Vos, P. Borst, K. van de, and Wetering Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays FASEB J. 26 2012 738 747
    • (2012) FASEB J. , vol.26 , pp. 738-747
    • Krumpochova, P.1    Sapthu, S.2    Brouwers, J.F.3    De Haas, M.4    De Vos, R.5    Borst, P.6    Van De, K.7    Wetering8
  • 62
    • 0033179095 scopus 로고    scopus 로고
    • Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: A Southwest Oncology Group Study
    • C.P. Leith, K.J. Kopecky, I.M. Chen, L. Eijdems, M.L. Slovak, T.S. McConnell, D.R. Head, J. Weick, M.R. Grever, F.R. Appelbaum, and C.L. Willman Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study Blood 94 1999 1086 1099
    • (1999) Blood , vol.94 , pp. 1086-1099
    • Leith, C.P.1    Kopecky, K.J.2    Chen, I.M.3    Eijdems, L.4    Slovak, M.L.5    McConnell, T.S.6    Head, D.R.7    Weick, J.8    Grever, M.R.9    Appelbaum, F.R.10    Willman, C.L.11
  • 63
    • 77953363931 scopus 로고    scopus 로고
    • Association of expression of MRP1, BCRP, LRP and ERCC1 with outcome of patients with locally advanced non-small cell lung cancer who received neoadjuvant chemotherapy
    • J. Li, Z.N. Li, L.C. Yu, Q.L. Bao, J.R. Wu, S.B. Shi, and X.Q. Li Association of expression of MRP1, BCRP, LRP and ERCC1 with outcome of patients with locally advanced non-small cell lung cancer who received neoadjuvant chemotherapy Lung Cancer 69 2010 116 122
    • (2010) Lung Cancer , vol.69 , pp. 116-122
    • Li, J.1    Li, Z.N.2    Yu, L.C.3    Bao, Q.L.4    Wu, J.R.5    Shi, S.B.6    Li, X.Q.7
  • 64
    • 76649129015 scopus 로고    scopus 로고
    • Expression of MRP1, BCRP, LRP and ERCC1 as prognostic factors in non-small cell lung cancer patients receiving postoperative cisplatin-based chemotherapy
    • X.Q. Li, J. Li, S.B. Shi, P. Chen, L.C. Yu, and Q.L. Bao Expression of MRP1, BCRP, LRP and ERCC1 as prognostic factors in non-small cell lung cancer patients receiving postoperative cisplatin-based chemotherapy Int. J. Biol. Markers 24 2009 230 237
    • (2009) Int. J. Biol. Markers , vol.24 , pp. 230-237
    • Li, X.Q.1    Li, J.2    Shi, S.B.3    Chen, P.4    Yu, L.C.5    Bao, Q.L.6
  • 65
    • 37349001082 scopus 로고    scopus 로고
    • Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response
    • Z.P. Lin, Y.L. Zhu, D.R. Johnson, K.P. Rice, T. Nottoli, B.C. Hains, J. McGrath, S.G. Waxman, and A.C. Sartorelli Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response Mol. Pharmacol. 73 2008 243 251
    • (2008) Mol. Pharmacol. , vol.73 , pp. 243-251
    • Lin, Z.P.1    Zhu, Y.L.2    Johnson, D.R.3    Rice, K.P.4    Nottoli, T.5    Hains, B.C.6    McGrath, J.7    Waxman, S.G.8    Sartorelli, A.C.9
  • 66
    • 80052252850 scopus 로고    scopus 로고
    • Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1
    • D. Liu, L. Ji, X. Tong, B. Pan, J.Y. Han, Y. Huang, Y.E. Chen, S. Pennathur, Y. Zhang, and L. Zheng Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1 Am. J. Physiol.: Cell Physiol. 301 2011 C739 C748
    • (2011) Am. J. Physiol.: Cell Physiol. , vol.301 , pp. C739-C748
    • Liu, D.1    Ji, L.2    Tong, X.3    Pan, B.4    Han, J.Y.5    Huang, Y.6    Chen, Y.E.7    Pennathur, S.8    Zhang, Y.9    Zheng, L.10
  • 67
    • 0030009305 scopus 로고    scopus 로고
    • Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport
    • D.W. Loe, K.C. Almquist, R.G. Deeley, and S.P. Cole Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport J. Biol. Chem. 271 1996 9675 9682
    • (1996) J. Biol. Chem. , vol.271 , pp. 9675-9682
    • Loe, D.W.1    Almquist, K.C.2    Deeley, R.G.3    Cole, S.P.4
  • 68
    • 0032534064 scopus 로고    scopus 로고
    • Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
    • D.W. Loe, R.G. Deeley, and S.P. Cole Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione Cancer Res. 58 1998 5130 5136
    • (1998) Cancer Res. , vol.58 , pp. 5130-5136
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.3
  • 69
    • 0030665969 scopus 로고    scopus 로고
    • Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
    • A. Lorico, G. Rappa, R.A. Finch, D. Yang, R.A. Flavell, and A.C. Sartorelli Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione Cancer Res. 57 1997 5238 5242
    • (1997) Cancer Res. , vol.57 , pp. 5238-5242
    • Lorico, A.1    Rappa, G.2    Finch, R.A.3    Yang, D.4    Flavell, R.A.5    Sartorelli, A.C.6
  • 70
    • 22344432207 scopus 로고    scopus 로고
    • Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice
    • J.M. Maher, A.L. Slitt, N.J. Cherrington, X. Cheng, and C.D. Klaassen Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice Drug Metab. Dispos. 33 2005 947 955
    • (2005) Drug Metab. Dispos. , vol.33 , pp. 947-955
    • Maher, J.M.1    Slitt, A.L.2    Cherrington, N.J.3    Cheng, X.4    Klaassen, C.D.5
  • 72
    • 84922002485 scopus 로고    scopus 로고
    • Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport - An update
    • Q. Mao, and J.D. Unadkat Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport - an update AAPS J. 17 2015 65 82
    • (2015) AAPS J. , vol.17 , pp. 65-82
    • Mao, Q.1    Unadkat, J.D.2
  • 73
    • 17844365262 scopus 로고    scopus 로고
    • The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin
    • G. Merino, J.W. Jonker, E. Wagenaar, A.E. van Herwaarden, and A.H. Schinkel The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin Mol. Pharmacol. 67 2005 1758 1764
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1758-1764
    • Merino, G.1    Jonker, J.W.2    Wagenaar, E.3    Van Herwaarden, A.E.4    Schinkel, A.H.5
  • 74
    • 78649648616 scopus 로고    scopus 로고
    • In vitro and in vivo evidence for the importance of breast cancer resistance protein transporters (BCRP/MXR/ABCP/ABCG2)
    • M.F. Fromm, R.B. Kim, Springer Berlin
    • H.E. Meyer zu Schwabedissen, and H.K. Kroemer In vitro and in vivo evidence for the importance of breast cancer resistance protein transporters (BCRP/MXR/ABCP/ABCG2) M.F. Fromm, R.B. Kim, Drug Transporters 2011 Springer Berlin 325 371
    • (2011) Drug Transporters , pp. 325-371
    • Meyer Zu Schwabedissen, H.E.1    Kroemer, H.K.2
  • 75
    • 0041668155 scopus 로고    scopus 로고
    • The role of P-glycoprotein in intestinal tumorigenesis: Disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice
    • Y. Mochida, K. Taguchi, S. Taniguchi, M. Tsuneyoshi, H. Kuwano, T. Tsuzuki, M. Kuwano, and M. Wada The role of P-glycoprotein in intestinal tumorigenesis: disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice Carcinogenesis 24 2003 1219 1224
    • (2003) Carcinogenesis , vol.24 , pp. 1219-1224
    • Mochida, Y.1    Taguchi, K.2    Taniguchi, S.3    Tsuneyoshi, M.4    Kuwano, H.5    Tsuzuki, T.6    Kuwano, M.7    Wada, M.8
  • 78
    • 84858002750 scopus 로고    scopus 로고
    • Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
    • K. Natarajan, Y. Xie, M.R. Baer, and D.D. Ross Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance Biochem. Pharmacol. 83 2012 1084 1103
    • (2012) Biochem. Pharmacol. , vol.83 , pp. 1084-1103
    • Natarajan, K.1    Xie, Y.2    Baer, M.R.3    Ross, D.D.4
  • 79
    • 33645104459 scopus 로고    scopus 로고
    • Altered hepatobiliary disposition of 5 (and 6)-carboxy-2′,7′-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice
    • K. Nezasa, X. Tian, M.J. Zamek-Gliszczynski, N.J. Patel, T.J. Raub, and K.L. Brouwer Altered hepatobiliary disposition of 5 (and 6)-carboxy-2′,7′-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice Drug Metab. Dispos. 34 2006 718 723
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 718-723
    • Nezasa, K.1    Tian, X.2    Zamek-Gliszczynski, M.J.3    Patel, N.J.4    Raub, T.J.5    Brouwer, K.L.6
  • 81
    • 84925285641 scopus 로고    scopus 로고
    • What do drug transporters really do?
    • S.K. Nigam What do drug transporters really do? Nat. Rev. Drug Discov. 14 2015 29 44
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 29-44
    • Nigam, S.K.1
  • 82
    • 84867419830 scopus 로고    scopus 로고
    • Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression
    • S. Nobili, I. Landini, T. Mazzei, and E. Mini Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression Med. Res. Rev. 32 2012 1220 1262
    • (2012) Med. Res. Rev. , vol.32 , pp. 1220-1262
    • Nobili, S.1    Landini, I.2    Mazzei, T.3    Mini, E.4
  • 84
    • 0030031845 scopus 로고    scopus 로고
    • Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma
    • M.D. Norris, S.B. Bordow, G.M. Marshall, P.S. Haber, S.L. Cohn, and M. Haber Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma N. Engl. J. Med. 334 1996 231 238
    • (1996) N. Engl. J. Med. , vol.334 , pp. 231-238
    • Norris, M.D.1    Bordow, S.B.2    Marshall, G.M.3    Haber, P.S.4    Cohn, S.L.5    Haber, M.6
  • 86
    • 84954156733 scopus 로고    scopus 로고
    • Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization
    • J.E. Obreque-Balboa, Q. Sun, G. Bernhardt, B. Konig, and A. Buschauer Flavonoid derivatives as selective ABCC1 modulators: synthesis and functional characterization Eur. J. Med. Chem. 109 2016 124 133
    • (2016) Eur. J. Med. Chem. , vol.109 , pp. 124-133
    • Obreque-Balboa, J.E.1    Sun, Q.2    Bernhardt, G.3    Konig, B.4    Buschauer, A.5
  • 89
    • 21744431708 scopus 로고    scopus 로고
    • Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1)
    • L. Payen, M. Gao, C. Westlake, A. Theis, S.P. Cole, and R.G. Deeley Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1) Mol. Pharmacol. 67 2005 1944 1953
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1944-1953
    • Payen, L.1    Gao, M.2    Westlake, C.3    Theis, A.4    Cole, S.P.5    Deeley, R.G.6
  • 93
    • 13444291906 scopus 로고    scopus 로고
    • 5-(2-Aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance
    • A.L. Ruchelman, P.J. Houghton, N. Zhou, A. Liu, L.F. Liu, and E.J. LaVoie 5-(2-Aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance J. Med. Chem. 48 2005 792 804
    • (2005) J. Med. Chem. , vol.48 , pp. 792-804
    • Ruchelman, A.L.1    Houghton, P.J.2    Zhou, N.3    Liu, A.4    Liu, L.F.5    LaVoie, E.J.6
  • 95
    • 84900314611 scopus 로고    scopus 로고
    • CRISPR-Cas systems for editing, regulating and targeting genomes
    • J.D. Sander, and J.K. Joung CRISPR-Cas systems for editing, regulating and targeting genomes Nat. Biotechnol. 32 2014 347 355
    • (2014) Nat. Biotechnol. , vol.32 , pp. 347-355
    • Sander, J.D.1    Joung, J.K.2
  • 96
    • 13444252391 scopus 로고    scopus 로고
    • MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia
    • M. Schaich, S. Soucek, C. Thiede, G. Ehninger, and T. Illmer MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia Br. J. Haematol. 128 2005 324 332
    • (2005) Br. J. Haematol. , vol.128 , pp. 324-332
    • Schaich, M.1    Soucek, S.2    Thiede, C.3    Ehninger, G.4    Illmer, T.5
  • 100
    • 77957154686 scopus 로고    scopus 로고
    • High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism
    • Y. Sekine, S.J. Demosky, J.A. Stonik, Y. Furuya, H. Koike, K. Suzuki, and A.T. Remaley High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism Mol. Cancer Res. 8 2010 1284 1294
    • (2010) Mol. Cancer Res. , vol.8 , pp. 1284-1294
    • Sekine, Y.1    Demosky, S.J.2    Stonik, J.A.3    Furuya, Y.4    Koike, H.5    Suzuki, K.6    Remaley, A.T.7
  • 102
    • 80052490064 scopus 로고    scopus 로고
    • Mammalian multidrug-resistance proteins (MRPs)
    • A.J. Slot, S.V. Molinski, and S.P. Cole Mammalian multidrug-resistance proteins (MRPs) Essays Biochem. 50 2011 179 207
    • (2011) Essays Biochem. , vol.50 , pp. 179-207
    • Slot, A.J.1    Molinski, S.V.2    Cole, S.P.3
  • 103
    • 84866922242 scopus 로고    scopus 로고
    • Anticancer activity of the cholesterol exporter ABCA1 gene
    • B. Smith, and H. Land Anticancer activity of the cholesterol exporter ABCA1 gene Cell Rep. 2 2012 580 590
    • (2012) Cell Rep. , vol.2 , pp. 580-590
    • Smith, B.1    Land, H.2
  • 105
    • 0041842584 scopus 로고    scopus 로고
    • Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate
    • M. Stark, L. Rothem, G. Jansen, G.L. Scheffer, I.D. Goldman, and Y.G. Assaraf Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate Mol. Pharmacol. 64 2003 220 227
    • (2003) Mol. Pharmacol. , vol.64 , pp. 220-227
    • Stark, M.1    Rothem, L.2    Jansen, G.3    Scheffer, G.L.4    Goldman, I.D.5    Assaraf, Y.G.6
  • 106
    • 0030775395 scopus 로고    scopus 로고
    • Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells
    • B.D. Stride, C.E. Grant, D.W. Loe, D.R. Hipfner, S.P. Cole, and R.G. Deeley Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells Mol. Pharmacol. 52 1997 344 353
    • (1997) Mol. Pharmacol. , vol.52 , pp. 344-353
    • Stride, B.D.1    Grant, C.E.2    Loe, D.W.3    Hipfner, D.R.4    Cole, S.P.5    Deeley, R.G.6
  • 108
    • 1542320076 scopus 로고    scopus 로고
    • Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol
    • C. Tang, A.M. Vaughan, and J.F. Oram Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol J. Biol. Chem. 279 2004 7622 7628
    • (2004) J. Biol. Chem. , vol.279 , pp. 7622-7628
    • Tang, C.1    Vaughan, A.M.2    Oram, J.F.3
  • 111
    • 33751104270 scopus 로고    scopus 로고
    • Multidrug resistance in small cell lung cancer: Expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease
    • N. Triller, P. Korosec, I. Kern, M. Kosnik, and A. Debeljak Multidrug resistance in small cell lung cancer: expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease Lung Cancer 54 2006 235 240
    • (2006) Lung Cancer , vol.54 , pp. 235-240
    • Triller, N.1    Korosec, P.2    Kern, I.3    Kosnik, M.4    Debeljak, A.5
  • 112
    • 0030920342 scopus 로고    scopus 로고
    • Multidrug resistance in breast cancer: A meta-analysis of MDR1/gp170 expression and its possible functional significance
    • B.J. Trock, F. Leonessa, and R. Clarke Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance J. Natl. Cancer Inst. 89 1997 917 931
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 917-931
    • Trock, B.J.1    Leonessa, F.2    Clarke, R.3
  • 113
    • 0008632564 scopus 로고
    • Expression of a full-length cDNA for the human "mDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine
    • K. Ueda, C. Cardarelli, M.M. Gottesman, and I. Pastan Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine Proc. Natl. Acad. Sci. U. S. A. 84 1987 3004 3008
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 3004-3008
    • Ueda, K.1    Cardarelli, C.2    Gottesman, M.M.3    Pastan, I.4
  • 116
    • 70350104791 scopus 로고    scopus 로고
    • Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo
    • K. van de Wetering, W. Feddema, J.B. Helms, J.F. Brouwers, and P. Borst Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo Gastroenterology 137 2009 1725 1735
    • (2009) Gastroenterology , vol.137 , pp. 1725-1735
    • Van De Wetering, K.1    Feddema, W.2    Helms, J.B.3    Brouwers, J.F.4    Borst, P.5
  • 117
    • 84868134869 scopus 로고    scopus 로고
    • ABCG2 functions as a general phytoestrogen sulfate transporter in vivo
    • K. van de Wetering, and S. Sapthu ABCG2 functions as a general phytoestrogen sulfate transporter in vivo FASEB J. 26 2012 4014 4024
    • (2012) FASEB J. , vol.26 , pp. 4014-4024
    • Van De Wetering, K.1    Sapthu, S.2
  • 118
    • 0141919551 scopus 로고    scopus 로고
    • The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
    • A.E. van Herwaarden, J.W. Jonker, E. Wagenaar, R.F. Brinkhuis, J.H. Schellens, J.H. Beijnen, and A.H. Schinkel The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Cancer Res. 63 2003 6447 6452
    • (2003) Cancer Res. , vol.63 , pp. 6447-6452
    • Van Herwaarden, A.E.1    Jonker, J.W.2    Wagenaar, E.3    Brinkhuis, R.F.4    Schellens, J.H.5    Beijnen, J.H.6    Schinkel, A.H.7
  • 119
    • 64749104937 scopus 로고    scopus 로고
    • ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation
    • A.M. Vaughan, C. Tang, and J.F. Oram ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation J. Lipid Res. 50 2009 285 292
    • (2009) J. Lipid Res. , vol.50 , pp. 285-292
    • Vaughan, A.M.1    Tang, C.2    Oram, J.F.3
  • 120
    • 34548364160 scopus 로고    scopus 로고
    • Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles
    • C. Vedhachalam, P.T. Duong, M. Nickel, D. Nguyen, P. Dhanasekaran, H. Saito, G.H. Rothblat, S. Lund-Katz, and M.C. Phillips Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles J. Biol. Chem. 282 2007 25123 25130
    • (2007) J. Biol. Chem. , vol.282 , pp. 25123-25130
    • Vedhachalam, C.1    Duong, P.T.2    Nickel, M.3    Nguyen, D.4    Dhanasekaran, P.5    Saito, H.6    Rothblat, G.H.7    Lund-Katz, S.8    Phillips, M.C.9
  • 122
    • 0030999641 scopus 로고    scopus 로고
    • Targeted expression of MYCN causes neuroblastoma in transgenic mice
    • W. Weiss, K. Aldape, G. Mohapatra, B. Feuerstein, and J. Bishop Targeted expression of MYCN causes neuroblastoma in transgenic mice EMBO J. 16 1997 2985 2995
    • (1997) EMBO J. , vol.16 , pp. 2985-2995
    • Weiss, W.1    Aldape, K.2    Mohapatra, G.3    Feuerstein, B.4    Bishop, J.5
  • 123
    • 0032812095 scopus 로고    scopus 로고
    • Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model
    • J.R. Wiener, K. Nakano, R.P. Kruzelock, C.D. Bucana, R.C. Bast Jr., and G.E. Gallick Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model Clin. Cancer Res. 5 1999 2164 2170
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2164-2170
    • Wiener, J.R.1    Nakano, K.2    Kruzelock, R.P.3    Bucana, C.D.4    Bast, R.C.5    Gallick, G.E.6
  • 127
    • 0032494133 scopus 로고    scopus 로고
    • Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage
    • J. Wijnholds, G.L. Scheffer, M. van der Valk, P. van der Valk, J.H. Beijnen, R.J. Scheper, and P. Borst Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage J. Exp. Med. 188 1998 797 808
    • (1998) J. Exp. Med. , vol.188 , pp. 797-808
    • Wijnholds, J.1    Scheffer, G.L.2    Van Der Valk, M.3    Van Der Valk, P.4    Beijnen, J.H.5    Scheper, R.J.6    Borst, P.7
  • 128
    • 84927130835 scopus 로고    scopus 로고
    • High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo
    • J. Xu, M. Yong, J. Li, X. Dong, T. Yu, X. Fu, and L. Hu High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo Oncol. Rep. 33 2015 2227 2234
    • (2015) Oncol. Rep. , vol.33 , pp. 2227-2234
    • Xu, J.1    Yong, M.2    Li, J.3    Dong, X.4    Yu, T.5    Fu, X.6    Hu, L.7
  • 130
    • 34250769986 scopus 로고    scopus 로고
    • Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients
    • T. Yamagata, H. Kusuhara, M. Morishita, K. Takayama, H. Benameur, and Y. Sugiyama Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients Drug Metab. Dispos. 35 2007 1142 1148
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 1142-1148
    • Yamagata, T.1    Kusuhara, H.2    Morishita, M.3    Takayama, K.4    Benameur, H.5    Sugiyama, Y.6
  • 131
    • 0035119989 scopus 로고    scopus 로고
    • In vitro substrate identification studies for p-glycoprotein-mediated transport: Species difference and predictability of in vivo results
    • M. Yamazaki, W.E. Neway, T. Ohe, I. Chen, J.F. Rowe, J.H. Hochman, M. Chiba, and J.H. Lin In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results J. Pharmacol. Exp. Ther. 296 2001 723 735
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 723-735
    • Yamazaki, M.1    Neway, W.E.2    Ohe, T.3    Chen, I.4    Rowe, J.F.5    Hochman, J.H.6    Chiba, M.7    Lin, J.H.8
  • 132
    • 84878107592 scopus 로고    scopus 로고
    • Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: Why has it failed to provide clinical benefit?
    • M. Yu, A. Ocana, and I.F. Tannock Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: why has it failed to provide clinical benefit? Cancer Metastasis Rev. 32 2013 211 227
    • (2013) Cancer Metastasis Rev. , vol.32 , pp. 211-227
    • Yu, M.1    Ocana, A.2    Tannock, I.F.3
  • 136
    • 81455158692 scopus 로고    scopus 로고
    • The ABCC4 gene is a promising target for pancreatic cancer therapy
    • Z. Zhang, J. Wang, B. Shen, C. Peng, and M. Zheng The ABCC4 gene is a promising target for pancreatic cancer therapy Gene 491 2012 194 199
    • (2012) Gene , vol.491 , pp. 194-199
    • Zhang, Z.1    Wang, J.2    Shen, B.3    Peng, C.4    Zheng, M.5
  • 137
    • 84858201901 scopus 로고    scopus 로고
    • The interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipids
    • G.J. Zhao, K. Yin, Y.C. Fu, and C.K. Tang The interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipids Mol. Med. (Cambridge, MA) 18 2012 149 158
    • (2012) Mol. Med. (Cambridge, MA) , vol.18 , pp. 149-158
    • Zhao, G.J.1    Yin, K.2    Fu, Y.C.3    Tang, C.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.