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Volumn 50, Issue 1, 2011, Pages 179-207

Mammalian multidrug-resistance proteins (MRPs)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA; MUS;

EID: 80052490064     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSE0500179     Document Type: Article
Times cited : (186)

References (73)
  • 1
    • 17544368685 scopus 로고    scopus 로고
    • Multidrug resistance proteins in toxicology: Role of P-glycoprotein, MRP1, MRP2 and BCRP (ABCG2) in tissue defense
    • Leslie, E.M., Deeley, R.G. and Cole, S.P.C. (2005) Multidrug resistance proteins in toxicology: role of P-glycoprotein, MRP1, MRP2 and BCRP (ABCG2) in tissue defense. Toxicol. Appl. Pharmacol. 204, 216-237
    • (2005) Toxicol. Appl. Pharmacol. , vol.204 , pp. 216-237
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.C.3
  • 2
    • 0035685449 scopus 로고    scopus 로고
    • Complete characterization of the human ABC gene family
    • Dean, M. and Allikmets, R. (2001) Complete characterization of the human ABC gene family. J. Bioenerg. Biomembr. 33, 475-479
    • (2001) J. Bioenerg. Biomembr. , vol.33 , pp. 475-479
    • Dean, M.1    Allikmets, R.2
  • 4
    • 33846688359 scopus 로고    scopus 로고
    • Structure and function of ABC transporters: The ATP switch provides fexible control
    • Linton, K.J. and Higgins, C.F. (2007) Structure and function of ABC transporters: the ATP switch provides fexible control. Pflügers Arch. 453, 555-567
    • (2007) Pflügers Arch. , vol.453 , pp. 555-567
    • Linton, K.J.1    Higgins, C.F.2
  • 6
    • 33745835398 scopus 로고    scopus 로고
    • Transmembrane transport of endo- and xenobiotics by membrane ATP-binding cassette multidrug resistance proteins
    • Deeley R.G., Westlake, C. and Cole, S.P.C. (2006) Transmembrane transport of endo- and xenobiotics by membrane ATP-binding cassette multidrug resistance proteins. Physiol. Rev. 86, 849-899
    • (2006) Physiol. Rev. , vol.86 , pp. 849-899
    • Deeley, R.G.1    Westlake, C.2    Cole, S.P.C.3
  • 7
    • 33745897902 scopus 로고    scopus 로고
    • Transport of glutathione and glutathione conjugates by MRP1
    • Cole, S.P.C. and Deeley, R.G. (2006) Transport of glutathione and glutathione conjugates by MRP1. Trends Pharmacol. Sci. 27, 438-446
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 438-446
    • Cole, S.P.C.1    Deeley, R.G.2
  • 9
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst, P., Evers, R., Kool, M. and Wijnholds, J. (2000) A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst. 92, 1295-1302
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3    Wijnholds, J.4
  • 11
    • 0026459859 scopus 로고
    • The ATP-dependent glutathione S-conjugate export pump
    • Ishikawa, T. (1992) The ATP-dependent glutathione S-conjugate export pump. Trends Biochem. Sci. 17, 463-468
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 463-468
    • Ishikawa, T.1
  • 12
    • 0029912351 scopus 로고    scopus 로고
    • ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump
    • Leier, I., Jedlitschky, G., Buchholz, U., Center, M., Cole, S.P.C., Deeley, R.G. and Keppler, D. (1996) ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump. Biochem. J. 314, 433-437
    • (1996) Biochem. J. , vol.314 , pp. 433-437
    • Leier, I.1    Jedlitschky, G.2    Buchholz, U.3    Center, M.4    Cole, S.P.C.5    Deeley, R.G.6    Keppler, D.7
  • 13
    • 0030665969 scopus 로고    scopus 로고
    • Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
    • Lorico, A., Rappa, G. Finch, R.A., Yang, D., Flavell, R.A. and Sartorelli, A.C. (1997) Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione. Cancer Res. 57, 5238-5242
    • (1997) Cancer Res. , vol.57 , pp. 5238-5242
    • Lorico, A.1    Rappa, G.2    Finch, R.A.3    Yang, D.4    Flavell, R.A.5    Sartorelli, A.C.6
  • 14
    • 52249106023 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein 1 as a major mediator of basal and apoptotic glutathione release
    • Marchan, R., Hammond, C.L. and Ballatori, N. (2008) Multidrug resistance-associated protein 1 as a major mediator of basal and apoptotic glutathione release. Biochim. Biophys. Acta 1778, 2413-2420
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 2413-2420
    • Marchan, R.1    Hammond, C.L.2    Ballatori, N.3
  • 15
    • 20244371290 scopus 로고    scopus 로고
    • Structural requirements for functional interaction of glutathione tripeptide analogs with the human multidrug resistance protein 1 (MRP1)
    • Leslie, E.M., Bowers, R.J., Deeley, R.G. and Cole, S.P.C. (2003) Structural requirements for functional interaction of glutathione tripeptide analogs with the human multidrug resistance protein 1 (MRP1). J. Pharmacol. Exp. Ther. 304, 643-653
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , pp. 643-653
    • Leslie, E.M.1    Bowers, R.J.2    Deeley, R.G.3    Cole, S.P.C.4
  • 16
    • 33744946318 scopus 로고    scopus 로고
    • Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1, ABCC1)
    • Rothnie, A., Callaghan, R., Deeley, R.G. and Cole, S.P.C. (2006) Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1, ABCC1). J. Biol. Chem. 281, 13906-13914
    • (2006) J. Biol. Chem. , vol.281 , pp. 13906-13914
    • Rothnie, A.1    Callaghan, R.2    Deeley, R.G.3    Cole, S.P.C.4
  • 19
    • 31844455959 scopus 로고    scopus 로고
    • Substrate recognition and transport by multidrug resistance protein 1 (ABCC1)
    • Deeley, R.G. and Cole, S.P.C. (2006) Substrate recognition and transport by multidrug resistance protein 1 (ABCC1). FEBS Lett. 580, 1103-1111
    • (2006) FEBS Lett. , vol.580 , pp. 1103-1111
    • Deeley, R.G.1    Cole, S.P.C.2
  • 20
    • 2442660256 scopus 로고    scopus 로고
    • Mutations of charged amino acids in or proximal to the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein, MRP1 (ABCC1)
    • Haimeur, A., Conseil, G., Deeley, R.G. and Cole, S.P.C. (2004) Mutations of charged amino acids in or proximal to the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein, MRP1 (ABCC1). Mol. Pharmacol. 65, 1375-1385
    • (2004) Mol. Pharmacol. , vol.65 , pp. 1375-1385
    • Haimeur, A.1    Conseil, G.2    Deeley, R.G.3    Cole, S.P.C.4
  • 21
    • 0035844142 scopus 로고    scopus 로고
    • Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport
    • Ito, K., Olsen, S.L., Qiu, W., Deeley R.G. and Cole, S.P.C. (2001) Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. J. Biol. Chem. 276, 15616-15624
    • (2001) J. Biol. Chem. , vol.276 , pp. 15616-15624
    • Ito, K.1    Olsen, S.L.2    Qiu, W.3    Deeley, R.G.4    Cole, S.P.C.5
  • 22
    • 67649398901 scopus 로고    scopus 로고
    • Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of TM6 and TM17 mutants of MRP1 (ABCC1)
    • Maeno, K., Nakajima, A., Conseil, G., Rothnie, A., Deeley, R.G. and Cole, S.P.C. (2009) Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of TM6 and TM17 mutants of MRP1 (ABCC1). Drug Metab. Dispos. 37, 1411-1420
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 1411-1420
    • Maeno, K.1    Nakajima, A.2    Conseil, G.3    Rothnie, A.4    Deeley, R.G.5    Cole, S.P.C.6
  • 24
    • 33846706434 scopus 로고    scopus 로고
    • The apical conjugate efflux pump ABCC2 (MRP2)
    • Nies, A.T. and Keppler, D. (2007) The apical conjugate efflux pump ABCC2 (MRP2). Pflügers Arch. 453, 643-659
    • (2007) Pflügers Arch. , vol.453 , pp. 643-659
    • Nies, A.T.1    Keppler, D.2
  • 25
    • 45749127384 scopus 로고    scopus 로고
    • Identification of regions required for apical membrane localization of human multidrug resistance protein 2
    • Bandler, P.E., Westlake, C.J., Grant, C.E., Cole, S.P.C. and Deeley, R.G. (2008) Identification of regions required for apical membrane localization of human multidrug resistance protein 2. Mol. Pharmacol. 74, 9-19
    • (2008) Mol. Pharmacol. , vol.74 , pp. 9-19
    • Bandler, P.E.1    Westlake, C.J.2    Grant, C.E.3    Cole, S.P.C.4    Deeley, R.G.5
  • 27
    • 0031468814 scopus 로고    scopus 로고
    • A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells
    • Koike, K., Kawabe, T., Tanaka, T., Toh, S., Uchiumi, T., Wada, M., Akiyama, S., Ono, M. and Kuwano, M. (1997) A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells. Cancer Res. 57, 5475-5479
    • (1997) Cancer Res. , vol.57 , pp. 5475-5479
    • Koike, K.1    Kawabe, T.2    Tanaka, T.3    Toh, S.4    Uchiumi, T.5    Wada, M.6    Akiyama, S.7    Ono, M.8    Kuwano, M.9
  • 28
    • 0037131880 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): Its impact on drug disposition
    • Suzuki, H. and Sugiyama, Y. (2002) Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition. Adv. Drug Delivery Rev. 54, 1311-1331
    • (2002) Adv. Drug Delivery Rev. , vol.54 , pp. 1311-1331
    • Suzuki, H.1    Sugiyama, Y.2
  • 29
    • 45949102855 scopus 로고    scopus 로고
    • Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs
    • Nies, A.T., Schwab, M. and Keppler, D. (2008) Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs. Expert Opin. Drug Metab. Toxicol. 4, 545-568
    • (2008) Expert Opin. Drug Metab. Toxicol. , vol.4 , pp. 545-568
    • Nies, A.T.1    Schwab, M.2    Keppler, D.3
  • 30
    • 0034671544 scopus 로고    scopus 로고
    • Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2
    • Ryu, S., Kawabe, T., Nada, S. and Yamaguchi, A. (2000) Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2. J. Biol. Chem. 275, 39617-39624
    • (2000) J. Biol. Chem. , vol.275 , pp. 39617-39624
    • Ryu, S.1    Kawabe, T.2    Nada, S.3    Yamaguchi, A.4
  • 31
    • 0035851106 scopus 로고    scopus 로고
    • 1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity
    • 1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. J. Biol. Chem. 276, 38108-38114
    • (2001) J. Biol. Chem. , vol.276 , pp. 38108-38114
    • Ito, K.1    Oleschuk, C.J.2    Westlake, C.3    Vasa, M.Z.4    Deeley, R.G.5    Cole, S.P.C.6
  • 32
    • 34547153777 scopus 로고    scopus 로고
    • Mutational analysis of a highly conserved proline residue in MRP1, MRP2 and MRP3 reveals a partially conserved function
    • Letourneau, I.J., Slot, A.J., Deeley, R.G. and Cole, S.P.C. (2007) Mutational analysis of a highly conserved proline residue in MRP1, MRP2 and MRP3 reveals a partially conserved function. Drug Metab. Dispos. 35, 1372-1379
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 1372-1379
    • Letourneau, I.J.1    Slot, A.J.2    Deeley, R.G.3    Cole, S.P.C.4
  • 35
    • 70349282243 scopus 로고    scopus 로고
    • Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4
    • Hirouchi, M., Kusuhara, H., Onuki, R., Ogilvie, B.W., Parkinson, A. and Sugiyama, Y. (2009) Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4. Drug Metab. Dispos. 37, 2103-2111
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 2103-2111
    • Hirouchi, M.1    Kusuhara, H.2    Onuki, R.3    Ogilvie, B.W.4    Parkinson, A.5    Sugiyama, Y.6
  • 36
    • 33846681607 scopus 로고    scopus 로고
    • Multidrug resistance-associated proteins 3, 4, and 5
    • Borst, P., de Wolf, C. and van de Wetering, K. (2007) Multidrug resistance-associated proteins 3, 4, and 5. Pflügers Arch. 453, 661-673
    • (2007) Pflügers Arch. , vol.453 , pp. 661-673
    • Borst, P.1    De Wolf, C.2    Van De Wetering, K.3
  • 38
    • 67650477192 scopus 로고    scopus 로고
    • Pharmacokinetic assessment of multiple ATP-binding cassette transporters: The power of combination knockout mice
    • Lagas, J.S., Vlaming, M.L.H. and Schinkel, A.H. (2009) Pharmacokinetic assessment of multiple ATP-binding cassette transporters: the power of combination knockout mice. Mol. Interventions 9, 136-145
    • (2009) Mol. Interventions , vol.9 , pp. 136-145
    • Lagas, J.S.1    Vlaming, M.L.H.2    Schinkel, A.H.3
  • 39
    • 33947430596 scopus 로고    scopus 로고
    • Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice
    • Kruh, G.D., Belinsky, M.G., Gallo, J.M. and Lee, K. (2007) Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice. Cancer Metastasis Rev. 26, 5-14
    • (2007) Cancer Metastasis Rev. , vol.26 , pp. 5-14
    • Kruh, G.D.1    Belinsky, M.G.2    Gallo, J.M.3    Lee, K.4
  • 40
    • 0034928631 scopus 로고    scopus 로고
    • Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver
    • Donner, M.G. and Keppler, D. (2001) Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver. Hepatology 34, 351-359
    • (2001) Hepatology , vol.34 , pp. 351-359
    • Donner, M.G.1    Keppler, D.2
  • 41
    • 70350104791 scopus 로고    scopus 로고
    • Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo
    • van de Wetering, K., Feddema, W., Helms, J.B., Brouwers, J.F. and Borst, P. (2009) Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo. Gastroenterology 137, 1725-1735
    • (2009) Gastroenterology , vol.137 , pp. 1725-1735
    • Van De Wetering, K.1    Feddema, W.2    Helms, J.B.3    Brouwers, J.F.4    Borst, P.5
  • 44
    • 76649133303 scopus 로고    scopus 로고
    • Pseudoxanthoma elasticum: Molecular genetics and putative pathomechanisms
    • Uitto, J., Li, Q., Jiang, Q. (2010) Pseudoxanthoma elasticum: molecular genetics and putative pathomechanisms. J. Invest. Dermatol. 130, 661-670
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 661-670
    • Uitto, J.1    Li, Q.2    Jiang, Q.3
  • 46
    • 0035951692 scopus 로고    scopus 로고
    • Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily
    • Hopper, E., Belinsky, M.G., Zeng, H., Tosolini, A., Testa, J.R. and Kruh, G.D. (2001) Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily. Cancer Lett. 162, 181-191
    • (2001) Cancer Lett. , vol.162 , pp. 181-191
    • Hopper, E.1    Belinsky, M.G.2    Zeng, H.3    Tosolini, A.4    Testa, J.R.5    Kruh, G.D.6
  • 48
    • 58249103864 scopus 로고    scopus 로고
    • Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B
    • Hopper-Borge, E., Xu, X., Shen, T., Shi, Z., Chen, Z.S. and Kruh G.D. (2009) Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B. Cancer Res. 69, 178-184
    • (2009) Cancer Res. , vol.69 , pp. 178-184
    • Hopper-Borge, E.1    Xu, X.2    Shen, T.3    Shi, Z.4    Chen, Z.S.5    Kruh, G.D.6
  • 53
    • 41349107158 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4): A versatile efflux transporter for drugs and signalling molecules
    • Russel, F.G., Koenderink, J.B. and Masereeuw, R. (2008) Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules. Trends Pharmacol. Sci. 29, 200-207
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 200-207
    • Russel, F.G.1    Koenderink, J.B.2    Masereeuw, R.3
  • 54
    • 6344265573 scopus 로고    scopus 로고
    • Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain
    • Nies, A.T., Jedlitschky, G., Konig, J., Herold-Mende, C., Steiner, H.H., Schmitt, H.P. and Keppler, D. (2004) Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain. Neuroscience 129, 349-360
    • (2004) Neuroscience , vol.129 , pp. 349-360
    • Nies, A.T.1    Jedlitschky, G.2    Konig, J.3    Herold-Mende, C.4    Steiner, H.H.5    Schmitt, H.P.6    Keppler, D.7
  • 55
    • 58149280218 scopus 로고    scopus 로고
    • Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells
    • Hoque, M.T., Conseil, G. and Cole, S.P.C. (2009) Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells. Biochem. Biophys. Res. Commun. 379, 60-64
    • (2009) Biochem. Biophys. Res. Commun. , vol.379 , pp. 60-64
    • Hoque, M.T.1    Conseil, G.2    Cole, S.P.C.3
  • 58
    • 0036186107 scopus 로고    scopus 로고
    • The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP
    • van Aubel, R.A.M., Smeets, P.H.E., Peters, J.G.P., Bindels, R.J.M. and Russel, F.G.M. (2002) The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. J. Am. Soc. Nephrol. 13, 595-603
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 595-603
    • Van Aubel, R.A.M.1    Smeets, P.H.E.2    Peters, J.G.P.3    Bindels, R.J.M.4    Russel, F.G.M.5
  • 59
    • 0043132421 scopus 로고    scopus 로고
    • The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
    • Reid, G., Wielinga, P., Zelcer, N., van der Heijden, I., Kuil, A., de Haas, M., Wijnholds, J. and Borst, P. (2003) The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc. Natl. Acad. Sci. U.S.A. 100, 9244-9249
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 9244-9249
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3    Van Der Heijden, I.4    Kuil, A.5    De Haas, M.6    Wijnholds, J.7    Borst, P.8
  • 64
    • 0036229673 scopus 로고    scopus 로고
    • Immunolocalization of multidrug resistance protein 5 in the human genitourinary system
    • Nies, A.T., Spring, H., Thon, W.F., Keppler, D. and Jedlitschky, G. (2002) Immunolocalization of multidrug resistance protein 5 in the human genitourinary system. J. Urol. 167, 2271-2275
    • (2002) J. Urol. , vol.167 , pp. 2271-2275
    • Nies, A.T.1    Spring, H.2    Thon, W.F.3    Keppler, D.4    Jedlitschky, G.5
  • 66
    • 20044383925 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports the monophosphorylated metabolites
    • Pratt, S., Shepard, R.L., Kandasamy, R.A., Johnston, P.A., Perry, W. and Dantzig, A.H. (2005) The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports the monophosphorylated metabolites. Mol. Cancer Ther. 4, 855-863
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 855-863
    • Pratt, S.1    Shepard, R.L.2    Kandasamy, R.A.3    Johnston, P.A.4    Perry, W.5    Dantzig, A.H.6
  • 67
    • 0034730755 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
    • Jedlitschky, G., Burchell, B. and Keppler, D. (2000) The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J. Biol. Chem. 275, 30069-30074
    • (2000) J. Biol. Chem. , vol.275 , pp. 30069-30074
    • Jedlitschky, G.1    Burchell, B.2    Keppler, D.3
  • 68
    • 0035834572 scopus 로고    scopus 로고
    • Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12
    • Yabuuchi, H., Shimizu, H., Takayanagi, S. and Ishikawa, T. (2001) Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12. Biochem. Biophys. Res. Commun. 288, 933-939
    • (2001) Biochem. Biophys. Res. Commun. , vol.288 , pp. 933-939
    • Yabuuchi, H.1    Shimizu, H.2    Takayanagi, S.3    Ishikawa, T.4
  • 69
    • 0035948584 scopus 로고    scopus 로고
    • Two new genes from the human ATP-biding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12
    • Tammur, J., Prades, C., Arnould, I., Rzhetsky, A., Hutchinson, A., Adachi, M., Schuetz, J.D., Swoboda, K.J., Ptacek, L.J., Roseir, M. et al. (2001) Two new genes from the human ATP-biding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12. Gene 273, 89-96
    • (2001) Gene , vol.273 , pp. 89-96
    • Tammur, J.1    Prades, C.2    Arnould, I.3    Rzhetsky, A.4    Hutchinson, A.5    Adachi, M.6    Schuetz, J.D.7    Swoboda, K.J.8    Ptacek, L.J.9    Roseir, M.10
  • 70
    • 67649354546 scopus 로고    scopus 로고
    • Earwax, osmidrosis, and breast cancer: Why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?
    • Toyoda, Y., Sakurai, A., Mitani, Y., Nakashima, M., Yoshiura, K., Nakagawa, H., Sakai, Y., Ota, I., Lezhava, A., Hayashizaki, Y. et al. (2009) Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type? FASEB J. 23, 2001-2013
    • (2009) FASEB J. , vol.23 , pp. 2001-2013
    • Toyoda, Y.1    Sakurai, A.2    Mitani, Y.3    Nakashima, M.4    Yoshiura, K.5    Nakagawa, H.6    Sakai, Y.7    Ota, I.8    Lezhava, A.9    Hayashizaki, Y.10
  • 71
    • 31144475523 scopus 로고    scopus 로고
    • Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system
    • Bortfeld, M., Rius, M., Konig, J., Herold-Mende, C., Nies, A.T. and Keppler, D. (2006) Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system. Neuroscience 137, 1247-1257
    • (2006) Neuroscience , vol.137 , pp. 1247-1257
    • Bortfeld, M.1    Rius, M.2    Konig, J.3    Herold-Mende, C.4    Nies, A.T.5    Keppler, D.6


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