The properties of the mucus barrier, a unique gel - how can nanoparticles cross it?

Therapeutic Delivery

Volumn 7, Issue 4, 2016, Pages 229-244

  Pearson, Jeffrey P ^a   Chater, Peter I ^a   Wilcox, Matthew D ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

aerodigestive tract; gel; mucin; mucus barrier; nanocarrier; nanoparticle; permeation; pores

Indexed keywords

ACTIN; DNA; MUCIN; MUCIN 1; MUCIN 2; MUCIN 5AC; MUCIN 5B; MUCIN 6; NANOPARTICLE; VON WILLEBRAND FACTOR; GEL;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CHROMATIN STRUCTURE; DENSITY GRADIENT; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; GEL; GELATION; GENE PRODUCT; HYDROPHOBICITY; IN VIVO STUDY; MEMBRANE TRANSPORT; MOLECULAR WEIGHT; MUCOLYSIS; MUCOSA; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTON TRANSPORT; REVIEW; TANDEM REPEAT; ZETA POTENTIAL; ANIMAL; CHEMISTRY; HUMAN; MUCUS; POROSITY; SURFACE PROPERTY;

ANIMALS; DRUG DELIVERY SYSTEMS; GELS; HUMANS; MUCINS; MUCUS; NANOPARTICLES; POROSITY; SURFACE PROPERTIES;

EID: 84962061591     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde-2015-0002     Document Type: Review

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