Diffusion of macromolecules and virus-like particles in human cervical mucus

Biophysical Journal

Volumn 81, Issue 4, 2001, Pages 1930-1937

  Olmsted, Stuart S ^a,e   Padgett, Janet L ^a   Yudin, Ashley I ^b   Whaley, Kevin J ^a,c,d   Moench, Thomas R ^d   Cone, Richard A ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Epicyte Pharmaceutical Inc   (United States)

^d REPROTECT INC   (United States)

^e UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; LYSOZYME; MICROSPHERE; MUCIN; MYOGLOBIN; POLYSTYRENE; PROTEIN;

ARTICLE; BINDING AFFINITY; DIFFUSION; ELECTRON MICROSCOPY; FEMALE; FLUORESCENCE; HUMAN; IMAGE ANALYSIS; MACROMOLECULE; NONHUMAN; PHOTOGRAPHY; PROTEIN TRANSPORT; UTERINE CERVIX MUCUS; VIRUS PARTICLE; WART VIRUS;

DNA VIRUSES; HERPES; HUMAN PAPILLOMA VIRUS; HUMAN PAPILLOMAVIRUS TYPES; MIRIDAE; NORWALK VIRUS; SIMPLEXVIRUS;

EID: 0034816264     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75844-4     Document Type: Article

References (44)

1. Structure of gastrointestinal mucus glycoproteins and the viscous and gel-forming properties of mucus
2. The structure and function of gastrointestinal mucus
3. Solute diffusion within hydrogels
4. An obstruction-scaling model for diffusion in homogenous hydrogels
5. Mobility measurement by analysis of fluorescence photobleaching recovery kinetics
6. Interaction of a salivary mucin-secretory immunoglobulin A complex with mucosal pathogens
7. Structure and macromolecular properties of cervical mucus glycoproteins
8. Human cervical mucus during the menstrual cycle and pregnancy in normal and pathological conditions
9. Mucus
10. Failure to show secretory IgA binding by rat intestinal mucin
11. A study of macromolecular diffusion through native porcine mucus
12. Estimation of effective diffusion coefficients of model solutes through gastric mucus: Assessment of a diffusion chamber technique based on spectrophotometric analysis
13. Incorporation of the green fluorescent protein into the herpes simplex virus type I capsid
14. Production, structure, and biologic relevance of gastrointestinal mucins
15. Elimination of Fc receptor binding of human immunoglobulin G in immunofluorescence assays for herpes simplex virus antibodies
16. Epifluorescence microscopy and image analysis used to measure diffusion coefficients in gel systems
17. Human salivary mucin MG1 selectively forms heterotypic complexes with amylase, proline-rich proteins, statherin, and histatins
18. The significance of the Fc part of antispermatozoal antibodies for the shaking phenomenon in the sperm-cervical mucus contact test
19. Nanosphere and microsphere uptake via Peyer's patches: Observation of the rate of uptake in the rat after a single oral dose
20. The sperm-cervical mucus contact test: A preliminary report
21. Quantitative disassembly and reassembly of human papillomavirus type II viruslike particles in vitro
22. Atomic force microscopy of the submolecular architecture of hydrated ocular mucins
23. Intestinal mucus gel and secretory antibody are barriers to Campylobacter jejuni adherence to INT 407 cells
24. Immune exclusion and mucus trapping during the rapid expulsion of Nippostrongylus brasiliensis from primed rats
25. Sulfomucins in the human body
26. Some aspects of diffusion in solution and a definition of a colloidal particle
27. Variances in mucus architecture as a cause of cervical factor infertility
28. Macromolecules released from polymers: Diffusion into unstirred fluids
29. Expression of human papillomavirus type II L1 protein in insect cells: In vivo and in vitro assembly of viruslike particles
30. Antibody diffusion in human cervical mucus
31. The physical properties of biogels and their permeability for macromolecular drugs and colloidal drug carriers
32. Intestinal mucin of germ-free rats. Biochemical and electron-microscopic characterization
33. Light microscopical observations on luminally administered dyes, dextrans, nanospheres and microspheres in the preepithelial mucus gel layer of the rat distal colon
34. Structural studies of recombinant Norwalk capsids
35. Nature of the charge distribution in proteins
36. Retardation of acid diffusion by pig gastric mucosa: A potential role in mucosal protection
37. Diffusion coefficient in native mucus gel of rat small intestine
38. Designing, building, and using a fluorescence recovery after photobleaching instrument
39. Human cervical mucus and its interaction with sperm: A fine-structural view
40. Structural studies of sialylated oligosaccharides of human midcycle cervical mucin
41. A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes