Two novel mucin genes down-regulated in colorectal cancer identified by differential display

Cancer Research

Volumn 59, Issue 16, 1999, Pages 4083-4089

  Williams, Stephanie J ^a,e   McGuckin, Michael A ^b   Gotley, David C ^c   Eyre, Helen J ^d   Sutherland, Grant R ^d   Antalis, Toni M ^a  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c PRINCESS ALEXANDRA HOSPITAL   (Australia)

^d WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^e MATER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; MUCIN;

AMINO ACID SEQUENCE; ARTICLE; COLORECTAL CANCER; DOWN REGULATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC PROCEDURES; HUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; COLORECTAL NEOPLASMS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUCINS; NEOPLASM PROTEINS; RATS; SEQUENCE ALIGNMENT;

EID: 0033566850     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Seregni, E., Botti, C., Massaron, S., Lombardo, C., Capobianco, A., Bogni, A., and Bombardieri, E. Structure, function and gene expression of epithelial mucins. Tumori, 83: 625-632, 1997.
2. Dessyn, J. L., Guyonnet-Duperat, V., Porchet, N., Aubert, J. P., and Laine, A. A. Human mucin gene MUC5B. The 10.7 kb large central exon encodes various alternate subdomains, resulting in a super-repeat. Structural evidence fora 11p15.5 gene family J. Biol. Chem., 272: 3168-3178, 1997.
3. Gendler, S. J., Spicer, A. P., Lalani, E. N., Duhig, T., Peat, N., Burchell, J., Pemberton, L., Boshell, M., and Taylor-Papadimitriou, J. Structure and biology of a carcinoma-associated mucin, MUC1. Am. Rev. Respir. Dis., 144: S42-S47, 1991.
4. Sheng, S., Wu, K., Carraway, K. L., and Fregien, N. Molecular cloning of the transmembrane component of the 13762 mammary adenocarcinoma sialomucin complex: a new member of the epidermal growth factor superfamily. J. Biol. Chem., 267: 16341-16346, 1992.
5. Moniaux, N., Nollet, S., Porchet, N., Degand P., Laine, A., and Aubert, J. Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin. Biochem. J., 338: 325-333, 1998.
6. Gum, J. R., Ho, J. J. L., Pratt, W. S., Hicks, J. W., Hill, A. S., Vinall, L. E., Roberton, A. M., Swallow, D. M., and Kim, Y. S. MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region. J. Biol. Chem., 272: 26678-26686, 1997.
7. Mcneer, R. R., Price-Schiavi, S. A., Komatsu, M., Fregien, N., Carraway, C. A. C., and Carraway, K. L. Sialomucin complex in tumors and tissues. Front. Biosci., 2: 449-459, 1998.
8. Rhodes, J. M. Mucins and inflammatory bowel disease. Q. J. Med., 90: 79-82, 1997.
9. Harris, A., and Reid, C. Cystic fibrosis and mucins. J. Med. Genet., 35: 82-83, 1997.
10. Chang, S., Dohrman, A. F., Basbaum, C. B., Ho, S. B., Tsuda, T., Toribara, N. W., Gum, J. R., and Kim, Y. S. Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer. Gastroenterology. 107: 28-36, 1994.
11. Weiss, A. A., Babyatsky, M. W., Ogata, S., Chen, A., and Itzkowitz, S. H. Expression of MUC2 and MUC3 mRNA in human normal, malignant, and inflammatory intestinal tissues. J. Histochem. Cytochem., 44: 1161-1166, 1996.
12. Itskowitz, S. H., Bloom, E. J., Kokal, W. A., Modin, G., Hakomori, S., and Kim, Y. S. Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients. Cancer (Phila.), 66: 1960-1966, 1990.
13. Bresalier, R. S., Byrd, J. C., Brodt, P., Ogata, S., Itzkowitz, S. H., and Yunker, C. K. Liver metastasis and adhesion to the sinusoidal endothelium by human colon cancer cells is related to mucin carbohydrate chain length. Int. J. Cancer, 76: 556-562, 1998.
14. Aoki, R., Tanaka, S., Haruma, K., Yoshihara, M., Sumii, K., Kajiyama, G., Shimamoto, F., and Kohno, N. MUC-1 expression as a predictor of the curative endoscopie treatment of submucosally invasive colorectal carcinoma. Dis. Colon Rectum, 41: 1262-1272, 1998.
15. Liang, P., and Pardee, A. B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science (Washington DC), 257: 967-971, 1992.
16. Chomczynski, P., and Sacchi, N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
17. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. Basic local alignment search tool. J. Mol. Biol., 215: 403-410, 1990.
18. Church, G. M., and Gilbert, W. Genomic sequencing. Proc. Natl. Acad. Sci. USA, 81: 1991-1995, 1984.
19. Gussow, D., Rein, R., Ginjaar, I., Hochstenbach, F., Seemann, G., Kottman, A., and Ploegh, H. L. The human β2-microglobulin gene. Primary structure and definition of the transcriptional unit. J. Immunol., 139: 3132-3138, 1987.
20. Callen, D. F., Baker, E., Eyre, H. J., Chernos, J. E., Bell, J. A., and Sutherland, G. R. Reassessment of two apparent deletions of chromosome 16p to an ins(11;16) and a t(1;16) by chromosome painting. Ann. Genet., 33: 219-221, 1990.
21. Van Klinken, B. J., Van Dijken, T. C., Oussoren, E., Buller, H. A., Dekker, J., and Einerhand, A. W. Molecular cloning of human MUC3 cDNA reveals a novel amino acid tandem repeat region. Biochem. Biophys. Res. Commun., 238: 143-148, 1997.
22. Zrihan-Licht, S., Baruch, A., Elroy-Stein, O., Keydar, I., and Wreschner, D. H. Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins cytokine receptor-like molecules. FEBS Lett., 356: 130-136, 1994.
23. Songyang, Z., Shoelson, S. E., McGlade, J., Olivier, P., Pawson, T., Bustello, X. R., Barbacid, M., Sabe, H., Hanafusa, H., Yi, T., Ren, R., Baltimore, D., Ratnofsky, S., Feldman, R. A., and Cantley, L. C. Specific motifs recognized by the SH2 domains of Csk, 3PB2, fps/fes, GRB2, HCP, SHC, Syk and Vav. Mol. Cell. Biol., 14: 2777-2785, 1994.
24. Gum, J. R., Hicks, J. W., Lagace, R. L., Byrd, J. C., Toribara, N. W., Siddiki, B., Fearney, F. J., Lamport, D. T., and Kim, Y. S. Molecular cloning of rat intestinal mucin. Lack of conservation between mammalian species. J. Biol. Chem., 266: 22733-22738, 1991.
25. Khatri, I. A., Forstner, G. G., and Forstner, J. F. The carboxyl-terminal sequence of rat intestinal mucin rMuc3 contains a putative transmembrane region and two EGF-like motifs. Biochim. Biophys. Acta, 1326: 7-11, 1997.
26. Shekels, L. L., Hunninghake, D. A., Tisdale, A. S., Gipson, I. K., Kieliszewski, M., Kozak, C. A, and Ho, S. B. Cloning and characterization of the mouse intestinal MUC3 mucin: 3′ sequence contains epidermal-growth-factor-like domains. Biochem. J., 330: 1301-1308, 1998.
27. Burgess, A. W. Growth control mechanisms in normal and transformed intestinal cells. Phil. Trans. R. Soc. Lond., 353: 903-909, 1998.
28. Satsangi, J., Parkes, M., Louis, E., Hashimoto, L., Kato, N., Welsh, K., Terwilliger, J. D., Lathrop, G. M., Bell, J. I., and Jewell, D. P. Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat. Genet., 14: 199-202, 1996.