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Volumn 11, Issue 3, 2016, Pages 216-225

PPARγ and wnt signaling in adipogenic and osteogenic differentiation of mesenchymal stem cells

Author keywords

Adipocyte differentiation; Mesenchymal stem cells; MicroRNA; Osteoblast differentiation; Peroxisome proliferatoractivated receptor ; Regenerative therapy; Wnt signaling

Indexed keywords

BETA CATENIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN EPSILON; MICRORNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RUNX2; WNT PROTEIN; WNT1 PROTEIN; WNT10B PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN; WNT7A PROTEIN; WNT8A PROTEIN; WNT8B PROTEIN; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; RUNX2 PROTEIN, HUMAN;

EID: 84961721892     PISSN: 1574888X     EISSN: None     Source Type: Journal    
DOI: 10.2174/1574888X10666150519093429     Document Type: Review
Times cited : (175)

References (129)
  • 1
    • 84873944895 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha suppresses the mesenchymal stem cell osteogenesis promoter miR-21 in estrogen deficiency-induced osteoporosis
    • Yang N, Wang G, Hu C, et al. Tumor necrosis factor alpha suppresses the mesenchymal stem cell osteogenesis promoter miR-21 in estrogen deficiency-induced osteoporosis. J Bone Miner Res 2013; 28(3): 559-73.
    • (2013) J Bone Miner Res , vol.28 , Issue.3 , pp. 559-573
    • Yang, N.1    Wang, G.2    Hu, C.3
  • 2
    • 84964063533 scopus 로고    scopus 로고
    • Osteoporosis in men: A review
    • Adler RA. Osteoporosis in men: a review. Bone Res 2014; 2: 14001.
    • (2014) Bone Res , vol.2
    • Adler, R.A.1
  • 3
    • 84992414403 scopus 로고    scopus 로고
    • Osteoporosis Treatment: When to Discontinue and When to Re-start
    • Adami S, Idolazzi L, Fracassi E, et al. Osteoporosis Treatment: When to Discontinue and When to Re-start. Bone Res 2013; 1(4): 323-35.
    • (2013) Bone Res , vol.1 , Issue.4 , pp. 323-335
    • Adami, S.1    Idolazzi, L.2    Fracassi, E.3
  • 4
    • 84923340927 scopus 로고    scopus 로고
    • Ligand binding and activation of PPARgamma by Firemaster(R) 550: Effects on adipogenesis and osteogenesis in vitro
    • Pillai HK, Fang M, Beglov D, et al. Ligand binding and activation of PPARgamma by Firemaster(R) 550: effects on adipogenesis and osteogenesis in vitro. Environ Health Perspect 2014; 122(11): 1225-32.
    • (2014) Environ Health Perspect , vol.122 , Issue.11 , pp. 1225-1232
    • Pillai, H.K.1    Fang, M.2    Beglov, D.3
  • 5
    • 58849130695 scopus 로고    scopus 로고
    • Anatomical variations in the harvest of anterolateral thigh flap perforators: A cadaveric and clinical study
    • Rozen WM, Ashton MW, Pan WR, et al. Anatomical variations in the harvest of anterolateral thigh flap perforators: a cadaveric and clinical study. Microsurgery 2009; 29(1): 16-23.
    • (2009) Microsurgery , vol.29 , Issue.1 , pp. 16-23
    • Rozen, W.M.1    Ashton, M.W.2    Pan, W.R.3
  • 6
    • 84915756216 scopus 로고    scopus 로고
    • Thiazolidinedioneinduced lipid droplet formation during osteogenic differentiation
    • van de Vyver M, Andrag E, Cockburn IL, et al. Thiazolidinedioneinduced lipid droplet formation during osteogenic differentiation. J Endocrinol 2014; 223(2): 119-32.
    • (2014) J Endocrinol , vol.223 , Issue.2 , pp. 119-132
    • van de Vyver, M.1    Andrag, E.2    Cockburn, I.L.3
  • 7
    • 84863469960 scopus 로고    scopus 로고
    • The effects of rosiglitazone on osteoblastic differentiation, osteoclast formation and bone resorption
    • Cho ES, Kim MK, Son YO, et al. The effects of rosiglitazone on osteoblastic differentiation, osteoclast formation and bone resorption. Mol Cells 2012; 33(2): 173-81.
    • (2012) Mol Cells , vol.33 , Issue.2 , pp. 173-181
    • Cho, E.S.1    Kim, M.K.2    Son, Y.O.3
  • 8
    • 33745839778 scopus 로고    scopus 로고
    • Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage
    • Yamashita A, Takada T, Nemoto K, et al. Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage. FEBS Lett 2006; 580(17): 4121-5.
    • (2006) FEBS Lett , vol.580 , Issue.17 , pp. 4121-4125
    • Yamashita, A.1    Takada, T.2    Nemoto, K.3
  • 9
    • 84884818014 scopus 로고    scopus 로고
    • PPARgamma silencing enhances osteogenic differentiation of human adipose-derived mesenchymal stem cells
    • Lee MJ, Chen HT, Ho ML, et al. PPARgamma silencing enhances osteogenic differentiation of human adipose-derived mesenchymal stem cells. J Cell Mol Med 2013; 17(9): 1188-93.
    • (2013) J Cell Mol Med , vol.17 , Issue.9 , pp. 1188-1193
    • Lee, M.J.1    Chen, H.T.2    Ho, M.L.3
  • 10
    • 68949180212 scopus 로고    scopus 로고
    • PPARgamma agonist rosiglitazone prevents inflammatory periodontal bone loss by inhibiting osteoclastogenesis
    • Hassumi MY, Silva-Filho VJ, Campos-Junior JC, et al. PPARgamma agonist rosiglitazone prevents inflammatory periodontal bone loss by inhibiting osteoclastogenesis. Int Immunopharmacol 2009; 9(10): 1150-8.
    • (2009) Int Immunopharmacol , vol.9 , Issue.10 , pp. 1150-1158
    • Hassumi, M.Y.1    Silva-Filho, V.J.2    Campos-Junior, J.C.3
  • 11
    • 84908888878 scopus 로고    scopus 로고
    • Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts
    • Henjes F, Lourido L, Ruiz-Romero C, et al. Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts. J Proteome Res 2014; 13(11): 5218-29.
    • (2014) J Proteome Res , vol.13 , Issue.11 , pp. 5218-5229
    • Henjes, F.1    Lourido, L.2    Ruiz-Romero, C.3
  • 12
    • 84922199194 scopus 로고    scopus 로고
    • TGF-beta signaling and the development of osteoarthritis
    • Shen J, Li S, Chen D. TGF-beta signaling and the development of osteoarthritis. Bone Res 2014; 2: 14016.
    • (2014) Bone Res , vol.2
    • Shen, J.1    Li, S.2    Chen, D.3
  • 13
    • 84895852523 scopus 로고    scopus 로고
    • [Destruction of the articular cartilage in osteoarthritis]
    • Okubo M, Okada Y. [Destruction of the articular cartilage in osteoarthritis]. Clin Calcium 2013; 23(12): 1705-13.
    • (2013) Clin Calcium , vol.23 , Issue.12 , pp. 1705-1713
    • Okubo, M.1    Okada, Y.2
  • 14
    • 84990974624 scopus 로고    scopus 로고
    • Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model
    • Zhang X, Zhu J, Liu F, et al. Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model. Bone Res 2014; 2: 14015.
    • (2014) Bone Res , vol.2
    • Zhang, X.1    Zhu, J.2    Liu, F.3
  • 15
    • 84891520511 scopus 로고    scopus 로고
    • Autologous bone marrow concentrate: Review and application of a novel intraarticular orthobiologic for cartilage disease
    • Sampson S, Botto-van Bemden A, Aufiero D. Autologous bone marrow concentrate: review and application of a novel intraarticular orthobiologic for cartilage disease. Phys Sportsmed 2013; 41(3): 7-18.
    • (2013) Phys Sportsmed , vol.41 , Issue.3 , pp. 7-18
    • Sampson, S.1    Botto-van Bemden, A.2    Aufiero, D.3
  • 16
    • 77649189822 scopus 로고    scopus 로고
    • Biological basis for the use of autologous bone marrow stromal cells in the treatment of congenital pseudarthrosis of the tibia
    • Granchi D, Devescovi V, Baglio SR, et al. Biological basis for the use of autologous bone marrow stromal cells in the treatment of congenital pseudarthrosis of the tibia. Bone 2010; 46(3): 780-8.
    • (2010) Bone , vol.46 , Issue.3 , pp. 780-788
    • Granchi, D.1    Devescovi, V.2    Baglio, S.R.3
  • 17
    • 84865757197 scopus 로고    scopus 로고
    • Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms
    • Otsuru S, Gordon PL, Shimono K, et al. Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms. Blood 2012; 120(9): 1933-41.
    • (2012) Blood , vol.120 , Issue.9 , pp. 1933-1941
    • Otsuru, S.1    Gordon, P.L.2    Shimono, K.3
  • 18
    • 84906931889 scopus 로고    scopus 로고
    • The current landscape of adiposederived stem cells in clinical applications
    • Lim MH, Ong WK, Sugii S. The current landscape of adiposederived stem cells in clinical applications. Expert Rev Mol Med 2014; 16: e8.
    • (2014) Expert Rev Mol Med , vol.16
    • Lim, M.H.1    Ong, W.K.2    Sugii, S.3
  • 19
    • 34249721434 scopus 로고    scopus 로고
    • Ectopic and in situ bone formation of adipose tissue-derived stromal cells in biphasic calcium phosphate nanocomposite
    • Lin Y, Wang T, Wu L, et al. Ectopic and in situ bone formation of adipose tissue-derived stromal cells in biphasic calcium phosphate nanocomposite. J Biomed Mater Res A 2007; 81(4): 900-10.
    • (2007) J Biomed Mater Res A , vol.81 , Issue.4 , pp. 900-910
    • Lin, Y.1    Wang, T.2    Wu, L.3
  • 20
    • 77953935060 scopus 로고    scopus 로고
    • Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK-dependent PPARgamma expression and phosphorylation
    • Wu L, Cai X, Dong H, et al. Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK-dependent PPARgamma expression and phosphorylation. J Cell Mol Med 2010; 14(4): 922-32.
    • (2010) J Cell Mol Med , vol.14 , Issue.4 , pp. 922-932
    • Wu, L.1    Cai, X.2    Dong, H.3
  • 21
    • 38649116985 scopus 로고    scopus 로고
    • Expression of Pcp4 gene during osteogenic differentiation of bone marrow mesenchymal stem cells in vitro
    • Xiao J, Wu Y, Chen R, et al. Expression of Pcp4 gene during osteogenic differentiation of bone marrow mesenchymal stem cells in vitro. Mol Cell Biochem 2008; 309(1-2): 143-50.
    • (2008) Mol Cell Biochem , vol.309 , Issue.1-2 , pp. 143-150
    • Xiao, J.1    Wu, Y.2    Chen, R.3
  • 22
    • 34248332602 scopus 로고    scopus 로고
    • Adipose-derived stem cells for regenerative medicine
    • Gimble JM, Katz AJ, Bunnell BA. Adipose-derived stem cells for regenerative medicine. Circ Res 2007; 100(9): 1249-60.
    • (2007) Circ Res , vol.100 , Issue.9 , pp. 1249-1260
    • Gimble, J.M.1    Katz, A.J.2    Bunnell, B.A.3
  • 23
    • 67649601033 scopus 로고    scopus 로고
    • Molecular switching of osteoblastogenesis versus adipogenesis: Implications for targeted therapies
    • Takada I, Kouzmenko AP, Kato S. Molecular switching of osteoblastogenesis versus adipogenesis: implications for targeted therapies. Expert Opin Ther Targets 2009; 13(5): 593-603.
    • (2009) Expert Opin Ther Targets , vol.13 , Issue.5 , pp. 593-603
    • Takada, I.1    Kouzmenko, A.P.2    Kato, S.3
  • 24
    • 84873558051 scopus 로고    scopus 로고
    • WNT signaling in bone homeostasis and disease: From human mutations to treatments
    • Baron R, Kneissel M. WNT signaling in bone homeostasis and disease: from human mutations to treatments. Nat Med 2013; 19(2): 179-92.
    • (2013) Nat Med , vol.19 , Issue.2 , pp. 179-192
    • Baron, R.1    Kneissel, M.2
  • 25
    • 78149450352 scopus 로고    scopus 로고
    • Obesity reduces bone density associated with activation of PPARgamma and suppression of Wnt/beta-catenin in rapidly growing male rats
    • Chen JR, Lazarenko OP, Wu X, et al. Obesity reduces bone density associated with activation of PPARgamma and suppression of Wnt/beta-catenin in rapidly growing male rats. PLoS One 2010; 5(10): e13704.
    • (2010) PLoS One , vol.5 , Issue.10
    • Chen, J.R.1    Lazarenko, O.P.2    Wu, X.3
  • 26
    • 70350451479 scopus 로고    scopus 로고
    • Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton
    • Almeida M, Ambrogini E, Han L, et al. Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton. J Biol Chem 2009; 284(40): 27438-48.
    • (2009) J Biol Chem , vol.284 , Issue.40 , pp. 27438-27448
    • Almeida, M.1    Ambrogini, E.2    Han, L.3
  • 27
    • 77951519413 scopus 로고    scopus 로고
    • Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases beta-catenin levels and leads to cell dedifferentiation and insulin resistance
    • Gustafson B, Smith U. Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases beta-catenin levels and leads to cell dedifferentiation and insulin resistance. J Biol Chem 2010; 285(18): 14031-41.
    • (2010) J Biol Chem , vol.285 , Issue.18 , pp. 14031-14041
    • Gustafson, B.1    Smith, U.2
  • 28
    • 84884817069 scopus 로고    scopus 로고
    • Wnt signaling behaves as a "master regulator" in the osteogenic and adipogenic commitment of human amniotic fluid mesenchymal stem cells
    • D'Alimonte I, Lannutti A, Pipino C, et al. Wnt signaling behaves as a "master regulator" in the osteogenic and adipogenic commitment of human amniotic fluid mesenchymal stem cells. Stem Cell Rev 2013; 9(5): 642-54.
    • (2013) Stem Cell Rev , vol.9 , Issue.5 , pp. 642-654
    • D'Alimonte, I.1    Lannutti, A.2    Pipino, C.3
  • 29
    • 79958121735 scopus 로고    scopus 로고
    • microRNAs in the regulation of adipogenesis and obesity
    • McGregor RA, Choi MS. microRNAs in the regulation of adipogenesis and obesity. Curr Mol Med 2011; 11(4): 304-16.
    • (2011) Curr Mol Med , vol.11 , Issue.4 , pp. 304-316
    • McGregor, R.A.1    Choi, M.S.2
  • 30
    • 84892823844 scopus 로고    scopus 로고
    • Osteoblast-adipocyte lineage plasticity in tissue development, maintenance and pathology
    • Berendsen AD, Olsen BR. Osteoblast-adipocyte lineage plasticity in tissue development, maintenance and pathology. Cell Mol Life Sci 2014; 71(3): 493-7.
    • (2014) Cell Mol Life Sci , vol.71 , Issue.3 , pp. 493-497
    • Berendsen, A.D.1    Olsen, B.R.2
  • 31
    • 65249179717 scopus 로고    scopus 로고
    • MicroRNAs and micromanaging the skeleton in disease, development and evolution
    • He X, Eberhart JK, Postlethwait JH. MicroRNAs and micromanaging the skeleton in disease, development and evolution. J Cell Mol Med 2009; 13(4): 606-18.
    • (2009) J Cell Mol Med , vol.13 , Issue.4 , pp. 606-618
    • He, X.1    Eberhart, J.K.2    Postlethwait, J.H.3
  • 32
    • 84897009273 scopus 로고    scopus 로고
    • Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts
    • Fakhry M, Hamade E, Badran B, et al. Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts. World J Stem Cells 2013; 5(4): 136-48.
    • (2013) World J Stem Cells , vol.5 , Issue.4 , pp. 136-148
    • Fakhry, M.1    Hamade, E.2    Badran, B.3
  • 33
    • 84861233517 scopus 로고    scopus 로고
    • Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: Implication to age-associated bone diseases and defects
    • Kim M, Kim C, Choi YS, et al. Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: implication to age-associated bone diseases and defects. Mech Ageing Dev 2012; 133(5): 215-25.
    • (2012) Mech Ageing Dev , vol.133 , Issue.5 , pp. 215-225
    • Kim, M.1    Kim, C.2    Choi, Y.S.3
  • 34
    • 84862777464 scopus 로고    scopus 로고
    • MicroRNA control of bone formation and homeostasis
    • Lian JB, Stein GS, van Wijnen AJ, et al. MicroRNA control of bone formation and homeostasis. Nat Rev Endocrinol 2012; 8(4): 212-27.
    • (2012) Nat Rev Endocrinol , vol.8 , Issue.4 , pp. 212-227
    • Lian, J.B.1    Stein, G.S.2    van Wijnen, A.J.3
  • 36
    • 84902547483 scopus 로고    scopus 로고
    • Induced pluripotent stem cellderived mesenchymal stem cell seeding on biofunctionalized calcium phosphate cements
    • TheinHan W, Liu J, Tang M, et al. Induced pluripotent stem cellderived mesenchymal stem cell seeding on biofunctionalized calcium phosphate cements. Bone Res 2013; 1(4): 371-84.
    • (2013) Bone Res , vol.1 , Issue.4 , pp. 371-384
    • TheinHan, W.1    Liu, J.2    Tang, M.3
  • 37
    • 84900030868 scopus 로고    scopus 로고
    • Osteogenesis of Adipose-Derived Stem Cells
    • Grottkau BE, Lin Y. Osteogenesis of Adipose-Derived Stem Cells. Bone Res 2013; 1(2): 133-45.
    • (2013) Bone Res , vol.1 , Issue.2 , pp. 133-145
    • Grottkau, B.E.1    Lin, Y.2
  • 38
    • 84875639225 scopus 로고    scopus 로고
    • Adipogenic and osteogenic differentiation of Lin(-)CD271(+)Sca-1(+) adipose-derived stem cells
    • Xiao J, Yang X, Jing W, et al. Adipogenic and osteogenic differentiation of Lin(-)CD271(+)Sca-1(+) adipose-derived stem cells. Mol Cell Biochem 2013; 377(1-2): 107-19.
    • (2013) Mol Cell Biochem , vol.377 , Issue.1-2 , pp. 107-119
    • Xiao, J.1    Yang, X.2    Jing, W.3
  • 39
    • 39149130013 scopus 로고    scopus 로고
    • Bone regeneration by BMP-2 enhanced adipose stem cells loading on alginate gel
    • Lin Y, Tang W, Wu L, et al. Bone regeneration by BMP-2 enhanced adipose stem cells loading on alginate gel. Histochem Cell Biol 2008; 129(2): 203-10.
    • (2008) Histochem Cell Biol , vol.129 , Issue.2 , pp. 203-210
    • Lin, Y.1    Tang, W.2    Wu, L.3
  • 40
    • 84904501121 scopus 로고    scopus 로고
    • Comparison of Effects of Mechanical Stretching on Osteogenic Potential of ASCs and BMSCs
    • Grottkau BE, Yang X, Zhang L, et al. Comparison of Effects of Mechanical Stretching on Osteogenic Potential of ASCs and BMSCs. Bone Res 2013; 1(3): 282-90.
    • (2013) Bone Res , vol.1 , Issue.3 , pp. 282-290
    • Grottkau, B.E.1    Yang, X.2    Zhang, L.3
  • 41
    • 84925044831 scopus 로고    scopus 로고
    • Mesenchymal stem cells as a potent cell source for articular cartilage regeneration
    • Baghaban Eslaminejad M, Malakooty Poor E. Mesenchymal stem cells as a potent cell source for articular cartilage regeneration. World J Stem Cells 2014; 6(3): 344-54.
    • (2014) World J Stem Cells , vol.6 , Issue.3 , pp. 344-354
    • Baghaban Eslaminejad, M.1    Malakooty Poor, E.2
  • 42
    • 30944456312 scopus 로고    scopus 로고
    • Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo
    • Lin Y, Luo E, Chen X, et al. Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo. J Cell Mol Med 2005; 9(4): 929-39.
    • (2005) J Cell Mol Med , vol.9 , Issue.4 , pp. 929-939
    • Lin, Y.1    Luo, E.2    Chen, X.3
  • 43
    • 84920870438 scopus 로고    scopus 로고
    • Tetraploid complementation proves pluripotency of induced pluripotent stem cells derived from adipose tissue
    • Zhou C, Cai X, Fu Y, et al. Tetraploid complementation proves pluripotency of induced pluripotent stem cells derived from adipose tissue. Cell Prolif 2015; 48(1): 39-46.
    • (2015) Cell Prolif , vol.48 , Issue.1 , pp. 39-46
    • Zhou, C.1    Cai, X.2    Fu, Y.3
  • 44
    • 84884245780 scopus 로고    scopus 로고
    • Repairing damaged tendon and muscle: Are mesenchymal stem cells and scaffolds the answer?
    • Davies BM, Morrey ME, Mouthuy PA, et al. Repairing damaged tendon and muscle: are mesenchymal stem cells and scaffolds the answer? Regen Med 2013; 8(5): 613-30.
    • (2013) Regen Med , vol.8 , Issue.5 , pp. 613-630
    • Davies, B.M.1    Morrey, M.E.2    Mouthuy, P.A.3
  • 45
    • 67650298997 scopus 로고    scopus 로고
    • [Use of mesenchymal stem cells from adult bone marrow for injured tissue repair]
    • Salamon A, Toldy E. [Use of mesenchymal stem cells from adult bone marrow for injured tissue repair]. Orv Hetil 2009; 150(27): 1259-65.
    • (2009) Orv Hetil , vol.150 , Issue.27 , pp. 1259-1265
    • Salamon, A.1    Toldy, E.2
  • 46
    • 84873813978 scopus 로고    scopus 로고
    • Regeneration of articular cartilage by adipose tissue derived mesenchymal stem cells: Perspectives from stem cell biology and molecular medicine
    • Wu L, Cai X, Zhang S, et al. Regeneration of articular cartilage by adipose tissue derived mesenchymal stem cells: perspectives from stem cell biology and molecular medicine. J Cell Physiol 2013; 228(5): 938-44.
    • (2013) J Cell Physiol , vol.228 , Issue.5 , pp. 938-944
    • Wu, L.1    Cai, X.2    Zhang, S.3
  • 47
    • 34248587094 scopus 로고    scopus 로고
    • Ectopic osteogenesis and chondrogenesis of bone marrow stromal stem cells in alginate system
    • Cai X, Lin Y, Ou G, et al. Ectopic osteogenesis and chondrogenesis of bone marrow stromal stem cells in alginate system. Cell Biol Int 2007; 31(8): 776-83.
    • (2007) Cell Biol Int , vol.31 , Issue.8 , pp. 776-783
    • Cai, X.1    Lin, Y.2    Ou, G.3
  • 48
    • 84919704863 scopus 로고    scopus 로고
    • Biological agents in management of osteoporosis
    • Tella SH, Gallagher JC. Biological agents in management of osteoporosis. Eur J Clin Pharmacol 2014; 70(11): 1291-301.
    • (2014) Eur J Clin Pharmacol , vol.70 , Issue.11 , pp. 1291-1301
    • Tella, S.H.1    Gallagher, J.C.2
  • 49
    • 84961709666 scopus 로고    scopus 로고
    • Roles of Circulating WNT-Signaling Proteins and WNT-Inhibitors in Human Adiposity, Insulin Resistance, Insulin Secretion, and Inflammation
    • Almario RU, Karakas SE. Roles of Circulating WNT-Signaling Proteins and WNT-Inhibitors in Human Adiposity, Insulin Resistance, Insulin Secretion, and Inflammation. Horm Metab Res 2014.
    • (2014) Horm Metab Res
    • Almario, R.U.1    Karakas, S.E.2
  • 50
    • 84862788783 scopus 로고    scopus 로고
    • Mechanical stretch inhibits adipogenesis and stimulates osteogenesis of adipose stem cells
    • Yang X, Cai X, Wang J, et al. Mechanical stretch inhibits adipogenesis and stimulates osteogenesis of adipose stem cells. Cell Prolif 2012; 45(2): 158-66.
    • (2012) Cell Prolif , vol.45 , Issue.2 , pp. 158-166
    • Yang, X.1    Cai, X.2    Wang, J.3
  • 51
    • 84878186794 scopus 로고    scopus 로고
    • Low-intensity pulsed ultrasound induced enhanced adipogenesis of adipose-derived stem cells
    • Fu N, Yang X, Ba K, et al. Low-intensity pulsed ultrasound induced enhanced adipogenesis of adipose-derived stem cells. Cell Prolif 2013; 46(3): 312-9.
    • (2013) Cell Prolif , vol.46 , Issue.3 , pp. 312-319
    • Fu, N.1    Yang, X.2    Ba, K.3
  • 52
    • 77953413397 scopus 로고    scopus 로고
    • The many facets of PPARgamma: Novel insights for the skeleton
    • Kawai M, Sousa KM, MacDougald OA, et al. The many facets of PPARgamma: novel insights for the skeleton. Am J Physiol Endocrinol Metab 2010; 299(1): E3-9.
    • (2010) Am J Physiol Endocrinol Metab , vol.299 , Issue.1 , pp. E3-E9
    • Kawai, M.1    Sousa, K.M.2    MacDougald, O.A.3
  • 53
    • 73349110430 scopus 로고    scopus 로고
    • Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis
    • Takada I, Kouzmenko AP, Kato S. Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis. Nat Rev Rheumatol 2009; 5(8): 442-7.
    • (2009) Nat Rev Rheumatol , vol.5 , Issue.8 , pp. 442-447
    • Takada, I.1    Kouzmenko, A.P.2    Kato, S.3
  • 54
    • 84886843429 scopus 로고    scopus 로고
    • FGF2 stimulates osteogenic differentiation through ERK induced TAZ expression
    • Byun MR, Kim AR, Hwang JH, et al. FGF2 stimulates osteogenic differentiation through ERK induced TAZ expression. Bone 2014; 58: 72-80.
    • (2014) Bone , vol.58 , pp. 72-80
    • Byun, M.R.1    Kim, A.R.2    Hwang, J.H.3
  • 55
    • 84886943235 scopus 로고    scopus 로고
    • Role of TAZ as mediator of Wnt signaling
    • Azzolin L, Zanconato F, Bresolin S, et al. Role of TAZ as mediator of Wnt signaling. Cell 2012; 151(7): 1443-56.
    • (2012) Cell , vol.151 , Issue.7 , pp. 1443-1456
    • Azzolin, L.1    Zanconato, F.2    Bresolin, S.3
  • 56
    • 84857440279 scopus 로고    scopus 로고
    • MicroRNAs regulate osteogenesis and chondrogenesis
    • Dong S, Yang B, Guo H, et al. MicroRNAs regulate osteogenesis and chondrogenesis. Biochem Biophys Res Commun 2012; 418(4): 587-91.
    • (2012) Biochem Biophys Res Commun , vol.418 , Issue.4 , pp. 587-591
    • Dong, S.1    Yang, B.2    Guo, H.3
  • 57
    • 84939883815 scopus 로고    scopus 로고
    • PPARgamma and PGC-1alpha as Therapeutic Targets in Parkinson's
    • Corona JC, Duchen MR. PPARgamma and PGC-1alpha as Therapeutic Targets in Parkinson's. Neurochem Res 2014.
    • (2014) Neurochem Res
    • Corona, J.C.1    Duchen, M.R.2
  • 59
    • 84868121739 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPAR-gamma) and neurodegenerative disorders
    • Chen YC, Wu JS, Tsai HD, et al. Peroxisome proliferator-activated receptor gamma (PPAR-gamma) and neurodegenerative disorders. Mol Neurobiol 2012; 46(1): 114-24.
    • (2012) Mol Neurobiol , vol.46 , Issue.1 , pp. 114-124
    • Chen, Y.C.1    Wu, J.S.2    Tsai, H.D.3
  • 60
    • 84875877935 scopus 로고    scopus 로고
    • Modulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modifications
    • Kim TH, Kim MY, Jo SH, et al. Modulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modifications. Yonsei Med J 2013; 54(3): 545-59.
    • (2013) Yonsei Med J , vol.54 , Issue.3 , pp. 545-559
    • Kim, T.H.1    Kim, M.Y.2    Jo, S.H.3
  • 61
    • 77956797254 scopus 로고    scopus 로고
    • PPAR-gamma Signaling Crosstalk in Mesenchymal Stem Cells
    • Takada I, Kouzmenko AP, Kato S. PPAR-gamma Signaling Crosstalk in Mesenchymal Stem Cells. PPAR Res 2010; 2010.
    • (2010) PPAR Res , pp. 2010
    • Takada, I.1    Kouzmenko, A.P.2    Kato, S.3
  • 62
    • 84880692987 scopus 로고    scopus 로고
    • Effects of bone morphogenetic protein-4 (BMP-4) on adipocyte differentiation from mouse adiposederived stem cells
    • Wei X, Li G, Yang X, et al. Effects of bone morphogenetic protein-4 (BMP-4) on adipocyte differentiation from mouse adiposederived stem cells. Cell Prolif 2013; 46(4): 416-24.
    • (2013) Cell Prolif , vol.46 , Issue.4 , pp. 416-424
    • Wei, X.1    Li, G.2    Yang, X.3
  • 63
    • 84860284206 scopus 로고    scopus 로고
    • Controlling a master switch of adipocyte development and insulin sensitivity: Covalent modifications of PPARgamma
    • Floyd ZE, Stephens JM. Controlling a master switch of adipocyte development and insulin sensitivity: covalent modifications of PPARgamma. Biochim Biophys Acta 2012; 1822(7): 1090-5.
    • (2012) Biochim Biophys Acta , vol.1822 , Issue.7 , pp. 1090-1095
    • Floyd, Z.E.1    Stephens, J.M.2
  • 64
    • 84901788219 scopus 로고    scopus 로고
    • PPAR agonists stimulate adipogenesis at the expense of osteoblast differentiation while inhibiting osteoclast formation and activity
    • Patel JJ, Butters OR, Arnett TR. PPAR agonists stimulate adipogenesis at the expense of osteoblast differentiation while inhibiting osteoclast formation and activity. Cell Biochem Funct 2014; 32(4): 368-77.
    • (2014) Cell Biochem Funct , vol.32 , Issue.4 , pp. 368-377
    • Patel, J.J.1    Butters, O.R.2    Arnett, T.R.3
  • 65
    • 84884702109 scopus 로고    scopus 로고
    • Mechanical compressive force inhibits adipogenesis of adipose stem cells
    • Li G, Fu N, Yang X, et al. Mechanical compressive force inhibits adipogenesis of adipose stem cells. Cell Prolif 2013; 46(5): 586-94.
    • (2013) Cell Prolif , vol.46 , Issue.5 , pp. 586-594
    • Li, G.1    Fu, N.2    Yang, X.3
  • 66
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009; 17(1): 9-26.
    • (2009) Dev Cell , vol.17 , Issue.1 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 67
    • 80054680272 scopus 로고    scopus 로고
    • Planar cell polarity in Drosophila
    • Maung SM, Jenny A. Planar cell polarity in Drosophila. Organogenesis 2011; 7(3): 165-79.
    • (2011) Organogenesis , vol.7 , Issue.3 , pp. 165-179
    • Maung, S.M.1    Jenny, A.2
  • 68
    • 84875249340 scopus 로고    scopus 로고
    • Beta-catenin versus the other armadillo catenins: Assessing our current view of canonical Wnt signaling
    • Miller RK, Hong JY, Munoz WA, et al. Beta-catenin versus the other armadillo catenins: assessing our current view of canonical Wnt signaling. Prog Mol Biol Transl Sci 2013; 116: 387-407.
    • (2013) Prog Mol Biol Transl Sci , vol.116 , pp. 387-407
    • Miller, R.K.1    Hong, J.Y.2    Munoz, W.A.3
  • 69
    • 80054975678 scopus 로고    scopus 로고
    • Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation
    • Lin GL, Hankenson KD. Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation. J Cell Biochem 2011; 112(12): 3491-501.
    • (2011) J Cell Biochem , vol.112 , Issue.12 , pp. 3491-3501
    • Lin, G.L.1    Hankenson, K.D.2
  • 70
    • 84878500600 scopus 로고    scopus 로고
    • Estrogen regulation of Dkk1 and Wnt/beta-Catenin signaling in neurodegenerative disease
    • Scott EL, Brann DW. Estrogen regulation of Dkk1 and Wnt/beta-Catenin signaling in neurodegenerative disease. Brain Res 2013; 1514: 63-74.
    • (2013) Brain Res , vol.1514 , pp. 63-74
    • Scott, E.L.1    Brann, D.W.2
  • 71
    • 84892605779 scopus 로고    scopus 로고
    • [Wnt signaling pathway--its role in regulation of cell metabolism]
    • Kozinski K, Dobrzyn A. [Wnt signaling pathway--its role in regulation of cell metabolism]. Postepy Hig Med Dosw (Online) 2013; 67: 1098-108.
    • (2013) Postepy Hig Med Dosw (Online) , vol.67 , pp. 1098-1108
    • Kozinski, K.1    Dobrzyn, A.2
  • 72
    • 58749106826 scopus 로고    scopus 로고
    • Beta-catenin-independent Wnt pathways: Signals, core proteins, and effectors
    • James RG, Conrad WH, Moon RT. Beta-catenin-independent Wnt pathways: signals, core proteins, and effectors. Methods Mol Biol 2008; 468: 131-44.
    • (2008) Methods Mol Biol , vol.468 , pp. 131-144
    • James, R.G.1    Conrad, W.H.2    Moon, R.T.3
  • 73
    • 84902679096 scopus 로고    scopus 로고
    • Wnt and the Wnt signaling pathway in bone development and disease
    • Wang Y, Li YP, Paulson C, et al. Wnt and the Wnt signaling pathway in bone development and disease. Front Biosci (Landmark Ed) 2014; 19: 379-407.
    • (2014) Front Biosci (Landmark Ed) , vol.19 , pp. 379-407
    • Wang, Y.1    Li, Y.P.2    Paulson, C.3
  • 74
    • 84881223991 scopus 로고    scopus 로고
    • Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer
    • Spreafico A, Tentler JJ, Pitts TM, et al. Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer. Clin Cancer Res 2013; 19(15): 4149-62.
    • (2013) Clin Cancer Res , vol.19 , Issue.15 , pp. 4149-4162
    • Spreafico, A.1    Tentler, J.J.2    Pitts, T.M.3
  • 75
    • 84898464531 scopus 로고    scopus 로고
    • Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways
    • Yamashita T, Uehara S, Udagawa N, et al. Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways. PLoS One 2014; 9(1): e85878.
    • (2014) PLoS One , vol.9 , Issue.1
    • Yamashita, T.1    Uehara, S.2    Udagawa, N.3
  • 76
    • 84886774405 scopus 로고    scopus 로고
    • A signal-amplification circuit between miR-218 and Wnt/beta-catenin signal promotes human adipose tissue-derived stem cells osteogenic differentiation
    • Zhang WB, Zhong WJ, Wang L. A signal-amplification circuit between miR-218 and Wnt/beta-catenin signal promotes human adipose tissue-derived stem cells osteogenic differentiation. Bone 2014; 58: 59-66.
    • (2014) Bone , vol.58 , pp. 59-66
    • Zhang, W.B.1    Zhong, W.J.2    Wang, L.3
  • 77
    • 72449208765 scopus 로고    scopus 로고
    • Wnt pathway genes in osteoporosis and osteoarthritis: Differential expression and genetic association study
    • Velasco J, Zarrabeitia MT, Prieto JR, et al. Wnt pathway genes in osteoporosis and osteoarthritis: differential expression and genetic association study. Osteoporos Int 2010; 21(1): 109-18.
    • (2010) Osteoporos Int , vol.21 , Issue.1 , pp. 109-118
    • Velasco, J.1    Zarrabeitia, M.T.2    Prieto, J.R.3
  • 78
    • 84880922830 scopus 로고    scopus 로고
    • Involvement of WNT/beta-catenin signaling in the treatment of osteoporosis
    • Rossini M, Gatti D, Adami S. Involvement of WNT/beta-catenin signaling in the treatment of osteoporosis. Calcif Tissue Int 2013; 93(2): 121-32.
    • (2013) Calcif Tissue Int , vol.93 , Issue.2 , pp. 121-132
    • Rossini, M.1    Gatti, D.2    Adami, S.3
  • 79
    • 84892700488 scopus 로고    scopus 로고
    • A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice
    • Maupin KA, Droscha CJ, Williams BO. A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice. Bone Res 2013; 1(1): 27-71.
    • (2013) Bone Res , vol.1 , Issue.1 , pp. 27-71
    • Maupin, K.A.1    Droscha, C.J.2    Williams, B.O.3
  • 80
    • 84978002518 scopus 로고    scopus 로고
    • Wnts' fashion statement: From body stature to dysplasia
    • Malhotra D, Yang Y. Wnts' fashion statement: from body stature to dysplasia. Bonekey Rep 2014; 3: 541.
    • (2014) Bonekey Rep , vol.3 , pp. 541
    • Malhotra, D.1    Yang, Y.2
  • 81
    • 56349162283 scopus 로고    scopus 로고
    • Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
    • Yadav VK, Ryu JH, Suda N, et al. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 2008; 135(5): 825-37.
    • (2008) Cell , vol.135 , Issue.5 , pp. 825-837
    • Yadav, V.K.1    Ryu, J.H.2    Suda, N.3
  • 82
    • 84859512183 scopus 로고    scopus 로고
    • Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity
    • Korvala J, Juppner H, Makitie O, et al. Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity. BMC Med Genet 2012; 13: 26.
    • (2012) BMC Med Genet , vol.13 , pp. 26
    • Korvala, J.1    Juppner, H.2    Makitie, O.3
  • 83
    • 80053466165 scopus 로고    scopus 로고
    • Wnt/Ca2+ signaling pathway: A brief overview
    • De A. Wnt/Ca2+ signaling pathway: a brief overview. Acta Biochim Biophys Sin (Shanghai) 2011; 43(10): 745-56.
    • (2011) Acta Biochim Biophys Sin (Shanghai) , vol.43 , Issue.10 , pp. 745-756
    • De, A.1
  • 84
    • 35648990464 scopus 로고    scopus 로고
    • Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK
    • Chang J, Sonoyama W, Wang Z, et al. Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK. J Biol Chem 2007; 282(42): 30938-48.
    • (2007) J Biol Chem , vol.282 , Issue.42 , pp. 30938-30948
    • Chang, J.1    Sonoyama, W.2    Wang, Z.3
  • 85
    • 84897095750 scopus 로고    scopus 로고
    • Noncanonical Wnt5a enhances Wnt/beta-catenin signaling during osteoblastogenesis
    • Okamoto M, Udagawa N, Uehara S, et al. Noncanonical Wnt5a enhances Wnt/beta-catenin signaling during osteoblastogenesis. Sci Rep 2014; 4: 4493.
    • (2014) Sci Rep , vol.4 , pp. 4493
    • Okamoto, M.1    Udagawa, N.2    Uehara, S.3
  • 86
    • 84882626417 scopus 로고    scopus 로고
    • Multiple functions of the noncanonical Wnt pathway
    • Gomez-Orte E, Saenz-Narciso B, Moreno S, et al. Multiple functions of the noncanonical Wnt pathway. Trends Genet 2013; 29(9): 545-53.
    • (2013) Trends Genet , vol.29 , Issue.9 , pp. 545-553
    • Gomez-Orte, E.1    Saenz-Narciso, B.2    Moreno, S.3
  • 87
    • 84858007236 scopus 로고    scopus 로고
    • Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis
    • Maeda K, Kobayashi Y, Udagawa N, et al. Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis. Nat Med 2012; 18(3): 405-12.
    • (2012) Nat Med , vol.18 , Issue.3 , pp. 405-412
    • Maeda, K.1    Kobayashi, Y.2    Udagawa, N.3
  • 88
    • 77949909802 scopus 로고    scopus 로고
    • Role of WNT-5a in the determination of human mesenchymal stem cells into preadipocytes
    • Bilkovski R, Schulte DM, Oberhauser F, et al. Role of WNT-5a in the determination of human mesenchymal stem cells into preadipocytes. J Biol Chem 2010; 285(9): 6170-8.
    • (2010) J Biol Chem , vol.285 , Issue.9 , pp. 6170-6178
    • Bilkovski, R.1    Schulte, D.M.2    Oberhauser, F.3
  • 89
    • 84892647657 scopus 로고    scopus 로고
    • Microvesicle-shuttled miR-130b reduces fat deposition in recipient primary cultured porcine adipocytes by inhibiting PPAR-g expression
    • Pan S, Yang X, Jia Y, et al. Microvesicle-shuttled miR-130b reduces fat deposition in recipient primary cultured porcine adipocytes by inhibiting PPAR-g expression. J Cell Physiol 2014; 229(5): 631-9.
    • (2014) J Cell Physiol , vol.229 , Issue.5 , pp. 631-639
    • Pan, S.1    Yang, X.2    Jia, Y.3
  • 90
    • 79953038248 scopus 로고    scopus 로고
    • MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling
    • Ling HY, Wen GB, Feng SD, et al. MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling. Clin Exp Pharmacol Physiol 2011; 38(4): 239-46.
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , Issue.4 , pp. 239-246
    • Ling, H.Y.1    Wen, G.B.2    Feng, S.D.3
  • 91
    • 84905108534 scopus 로고    scopus 로고
    • Transcriptional activation of PIK3R1 by PPARgamma in adipocytes
    • Kim YJ, Kim HJ, Chung KY, et al. Transcriptional activation of PIK3R1 by PPARgamma in adipocytes. Mol Biol Rep 2014; 41(8): 5267-72.
    • (2014) Mol Biol Rep , vol.41 , Issue.8 , pp. 5267-5272
    • Kim, Y.J.1    Kim, H.J.2    Chung, K.Y.3
  • 92
    • 69949099167 scopus 로고    scopus 로고
    • CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes
    • Ling HY, Ou HS, Feng SD, et al. CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes. Clin Exp Pharmacol Physiol 2009; 36(9): e32-9.
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , Issue.9 , pp. e32-e39
    • Ling, H.Y.1    Ou, H.S.2    Feng, S.D.3
  • 93
    • 84885026773 scopus 로고    scopus 로고
    • MiRNA-181a regulates adipogenesis by targeting tumor necrosis factor-alpha (TNF-alpha) in the porcine model
    • Li H, Chen X, Guan L, et al. MiRNA-181a regulates adipogenesis by targeting tumor necrosis factor-alpha (TNF-alpha) in the porcine model. PLoS One 2013; 8(10): e71568.
    • (2013) PLoS One , vol.8 , Issue.10
    • Li, H.1    Chen, X.2    Guan, L.3
  • 94
    • 65549144017 scopus 로고    scopus 로고
    • MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity
    • Xie H, Lim B, Lodish HF. MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes 2009; 58(5): 1050-7.
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1050-1057
    • Xie, H.1    Lim, B.2    Lodish, H.F.3
  • 95
    • 80054053675 scopus 로고    scopus 로고
    • MiR-143 enhances adipogenic differentiation of 3T3-L1 cells through targeting the coding region of mouse pleiotrophin
    • Yi C, Xie WD, Li F, et al. MiR-143 enhances adipogenic differentiation of 3T3-L1 cells through targeting the coding region of mouse pleiotrophin. FEBS Lett 2011; 585(20): 3303-9.
    • (2011) FEBS Lett , vol.585 , Issue.20 , pp. 3303-3309
    • Yi, C.1    Xie, W.D.2    Li, F.3
  • 96
    • 84903398045 scopus 로고    scopus 로고
    • MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity
    • Chen L, Dai YM, Ji CB, et al. MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity. Mol Cell Endocrinol 2014; 393(1-2): 65-74.
    • (2014) Mol Cell Endocrinol , vol.393 , Issue.1-2 , pp. 65-74
    • Chen, L.1    Dai, Y.M.2    Ji, C.B.3
  • 97
    • 84867423956 scopus 로고    scopus 로고
    • Modeling the role of peroxisome proliferator-activated receptor gamma and microRNA-146 in mucosal immune responses to Clostridium difficile
    • Viladomiu M, Hontecillas R, Pedragosa M, et al. Modeling the role of peroxisome proliferator-activated receptor gamma and microRNA-146 in mucosal immune responses to Clostridium difficile. PLoS One 2012; 7(10): e47525.
    • (2012) PLoS One , vol.7 , Issue.10
    • Viladomiu, M.1    Hontecillas, R.2    Pedragosa, M.3
  • 98
    • 84889025854 scopus 로고    scopus 로고
    • MicroRNA-27 (miR-27) targets prohibitin and impairs adipocyte differentiation and mitochondrial function in human adipose-derived stem cells
    • Kang T, Lu W, Xu W, et al. MicroRNA-27 (miR-27) targets prohibitin and impairs adipocyte differentiation and mitochondrial function in human adipose-derived stem cells. J Biol Chem 2013; 288(48): 34394-402.
    • (2013) J Biol Chem , vol.288 , Issue.48 , pp. 34394-34402
    • Kang, T.1    Lu, W.2    Xu, W.3
  • 99
    • 63049108381 scopus 로고    scopus 로고
    • A role of miR-27 in the regulation of adipogenesis
    • Lin Q, Gao Z, Alarcon RM, et al. A role of miR-27 in the regulation of adipogenesis. Febs j 2009; 276(8): 2348-58.
    • (2009) Febs j , vol.276 , Issue.8 , pp. 2348-2358
    • Lin, Q.1    Gao, Z.2    Alarcon, R.M.3
  • 100
    • 84894581857 scopus 로고    scopus 로고
    • A novel negative regulator of adipogenesis: MicroRNA-363
    • Chen L, Cui J, Hou J, et al. A novel negative regulator of adipogenesis: microRNA-363. Stem Cells 2014; 32(2): 510-20.
    • (2014) Stem Cells , vol.32 , Issue.2 , pp. 510-520
    • Chen, L.1    Cui, J.2    Hou, J.3
  • 101
    • 84908322815 scopus 로고    scopus 로고
    • MiR-29a is an enhancer of mineral deposition in bone-derived systems
    • Roberto VP, Tiago DM, Silva IA, et al. MiR-29a is an enhancer of mineral deposition in bone-derived systems. Arch Biochem Biophys 2014; 564: 173-83.
    • (2014) Arch Biochem Biophys , vol.564 , pp. 173-183
    • Roberto, V.P.1    Tiago, D.M.2    Silva, I.A.3
  • 102
    • 84915791996 scopus 로고    scopus 로고
    • microRNA-103a functions as a mechnosensitive microRNA to inhibit bone formation through targeting Runx2
    • Zuo B, Zhu JF, Li J, et al. microRNA-103a functions as a mechnosensitive microRNA to inhibit bone formation through targeting Runx2. J Bone Miner Res 2014.
    • (2014) J Bone Miner Res
    • Zuo, B.1    Zhu, J.F.2    Li, J.3
  • 103
    • 79960102602 scopus 로고    scopus 로고
    • The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression
    • Wen X, Cawthorn WP, MacDougald OA, et al. The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression. Biomaterials 2011; 32(27): 6478-86.
    • (2011) Biomaterials , vol.32 , Issue.27 , pp. 6478-6486
    • Wen, X.1    Cawthorn, W.P.2    MacDougald, O.A.3
  • 104
    • 84903751773 scopus 로고    scopus 로고
    • The effects of PPARgamma inhibition on gene expression and the progression of induced osteogenic differentiation of human mesenchymal stem cells
    • Graneli C, Karlsson C, Brisby H, et al. The effects of PPARgamma inhibition on gene expression and the progression of induced osteogenic differentiation of human mesenchymal stem cells. Connect Tissue Res 2014; 55(4): 262-74.
    • (2014) Connect Tissue Res , vol.55 , Issue.4 , pp. 262-274
    • Graneli, C.1    Karlsson, C.2    Brisby, H.3
  • 105
    • 84896790441 scopus 로고    scopus 로고
    • The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT
    • Grunberg JR, Hammarstedt A, Hedjazifar S, et al. The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT. J Biol Chem 2014; 289(10): 6899-907.
    • (2014) J Biol Chem , vol.289 , Issue.10 , pp. 6899-6907
    • Grunberg, J.R.1    Hammarstedt, A.2    Hedjazifar, S.3
  • 106
    • 84873712772 scopus 로고    scopus 로고
    • WISP2 regulates preadipocyte commitment and PPARgamma activation by BMP4
    • Hammarstedt A, Hedjazifar S, Jenndahl L, et al. WISP2 regulates preadipocyte commitment and PPARgamma activation by BMP4. Proc Natl Acad Sci USA 2013; 110(7): 2563-8.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.7 , pp. 2563-2568
    • Hammarstedt, A.1    Hedjazifar, S.2    Jenndahl, L.3
  • 107
    • 35648981937 scopus 로고    scopus 로고
    • Wnt3a signaling promotes proliferation, myogenic differentiation, and migration of rat bone marrow mesenchymal stem cells
    • Shang YC, Wang SH, Xiong F, et al. Wnt3a signaling promotes proliferation, myogenic differentiation, and migration of rat bone marrow mesenchymal stem cells. Acta Pharmacol Sin 2007; 28(11): 1761-74.
    • (2007) Acta Pharmacol Sin , vol.28 , Issue.11 , pp. 1761-1774
    • Shang, Y.C.1    Wang, S.H.2    Xiong, F.3
  • 108
    • 71449104516 scopus 로고    scopus 로고
    • Development of stepwise osteogenesis-mimicking matrices for the regulation of mesenchymal stem cell functions
    • Hoshiba T, Kawazoe N, Tateishi T, et al. Development of stepwise osteogenesis-mimicking matrices for the regulation of mesenchymal stem cell functions. J Biol Chem 2009; 284(45): 31164-73.
    • (2009) J Biol Chem , vol.284 , Issue.45 , pp. 31164-31173
    • Hoshiba, T.1    Kawazoe, N.2    Tateishi, T.3
  • 109
    • 79953708195 scopus 로고    scopus 로고
    • Role of WNT signalling in the determination of human mesenchymal stem cells into preadipocytes
    • Laudes M. Role of WNT signalling in the determination of human mesenchymal stem cells into preadipocytes. J Mol Endocrinol 2011; 46(2): R65-72.
    • (2011) J Mol Endocrinol , vol.46 , Issue.2 , pp. R65-R72
    • Laudes, M.1
  • 110
    • 84864925509 scopus 로고    scopus 로고
    • LRP6 mediates Wnt/betacatenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells
    • Perobner I, Karow M, Jochum M, et al. LRP6 mediates Wnt/betacatenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells. Int J Biochem Cell Biol 2012; 44(11): 1970-82.
    • (2012) Int J Biochem Cell Biol , vol.44 , Issue.11 , pp. 1970-1982
    • Perobner, I.1    Karow, M.2    Jochum, M.3
  • 111
    • 77949273271 scopus 로고    scopus 로고
    • Epigenetic regulation of latent HSV-1 gene expression
    • Bloom DC, Giordani NV, Kwiatkowski DL. Epigenetic regulation of latent HSV-1 gene expression. Biochim Biophys Acta 2010; 1799(3-4): 246-56.
    • (2010) Biochim Biophys Acta , vol.1799 , Issue.3-4 , pp. 246-256
    • Bloom, D.C.1    Giordani, N.V.2    Kwiatkowski, D.L.3
  • 112
    • 84900015789 scopus 로고    scopus 로고
    • The epigenetic promotion of osteogenic differentiation of human adipose-derived stem cells by the genetic and chemical blockade of histone demethylase LSD1
    • Ge W, Liu Y, Chen T, et al. The epigenetic promotion of osteogenic differentiation of human adipose-derived stem cells by the genetic and chemical blockade of histone demethylase LSD1. Biomaterials 2014; 35(23): 6015-25.
    • (2014) Biomaterials , vol.35 , Issue.23 , pp. 6015-6025
    • Ge, W.1    Liu, Y.2    Chen, T.3
  • 113
    • 84896081036 scopus 로고    scopus 로고
    • Kirenol inhibits adipogenesis through activation of the Wnt/beta-catenin signaling pathway in 3T3-L1 adipocytes
    • Kim MB, Song Y, Kim C, et al. Kirenol inhibits adipogenesis through activation of the Wnt/beta-catenin signaling pathway in 3T3-L1 adipocytes. Biochem Biophys Res Commun 2014; 445(2): 433-8.
    • (2014) Biochem Biophys Res Commun , vol.445 , Issue.2 , pp. 433-438
    • Kim, M.B.1    Song, Y.2    Kim, C.3
  • 114
    • 84884850444 scopus 로고    scopus 로고
    • Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor gamma
    • Lee YH, Kim SH, Lee YJ, et al. Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor gamma. Cell Mol Life Sci 2013; 70(20): 3959-71.
    • (2013) Cell Mol Life Sci , vol.70 , Issue.20 , pp. 3959-3971
    • Lee, Y.H.1    Kim, S.H.2    Lee, Y.J.3
  • 115
    • 84902054120 scopus 로고    scopus 로고
    • Downregulation of PPARgamma by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential
    • Sun J, Wang Y, Li Y, et al. Downregulation of PPARgamma by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential. J Transl Med 2014; 12: 168.
    • (2014) J Transl Med , vol.12 , pp. 168
    • Sun, J.1    Wang, Y.2    Li, Y.3
  • 116
    • 84893826747 scopus 로고    scopus 로고
    • Hypoxia mediates mutual repression between microRNA-27a and PPARgamma in the pulmonary vasculature
    • Kang BY, Park KK, Green DE, et al. Hypoxia mediates mutual repression between microRNA-27a and PPARgamma in the pulmonary vasculature. PLoS One 2013; 8(11): e79503.
    • (2013) PLoS One , vol.8 , Issue.11
    • Kang, B.Y.1    Park, K.K.2    Green, D.E.3
  • 117
    • 84872687459 scopus 로고    scopus 로고
    • MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling
    • Zhang JF, Fu WM, He ML, et al. MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling. RNA Biol 2011; 8(5): 829-38.
    • (2011) RNA Biol , vol.8 , Issue.5 , pp. 829-838
    • Zhang, J.F.1    Fu, W.M.2    He, M.L.3
  • 118
    • 84899453076 scopus 로고    scopus 로고
    • MicroRNA-33b downregulates the differentiation and development of porcine preadipocytes
    • Taniguchi M, Nakajima I, Chikuni K, et al. MicroRNA-33b downregulates the differentiation and development of porcine preadipocytes. Mol Biol Rep 2014; 41(2): 1081-90.
    • (2014) Mol Biol Rep , vol.41 , Issue.2 , pp. 1081-1090
    • Taniguchi, M.1    Nakajima, I.2    Chikuni, K.3
  • 119
    • 77952448162 scopus 로고    scopus 로고
    • A deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway
    • Qin L, Chen Y, Niu Y, et al. A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway. BMC Genomics 2010; 11: 320.
    • (2010) BMC Genomics , vol.11 , pp. 320
    • Qin, L.1    Chen, Y.2    Niu, Y.3
  • 120
    • 84887426861 scopus 로고    scopus 로고
    • miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6
    • Wang J, Guan X, Guo F, et al. miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6. Cell Death Dis 2013; 4: e845.
    • (2013) Cell Death Dis , vol.4
    • Wang, J.1    Guan, X.2    Guo, F.3
  • 121
    • 84892803671 scopus 로고    scopus 로고
    • MicroRNA-344 inhibits 3T3-L1 cell differentiation via targeting GSK3beta of Wnt/beta-catenin signaling pathway
    • Chen H, Wang S, Chen L, et al. MicroRNA-344 inhibits 3T3-L1 cell differentiation via targeting GSK3beta of Wnt/beta-catenin signaling pathway. FEBS Lett 2014; 588(3): 429-35.
    • (2014) FEBS Lett , vol.588 , Issue.3 , pp. 429-435
    • Chen, H.1    Wang, S.2    Chen, L.3
  • 122
    • 84885830630 scopus 로고    scopus 로고
    • MicroRNA-29a ameliorates glucocorticoid-induced suppression of osteoblast differentiation by regulating beta-catenin acetylation
    • Ko JY, Chuang PC, Chen MW, et al. MicroRNA-29a ameliorates glucocorticoid-induced suppression of osteoblast differentiation by regulating beta-catenin acetylation. Bone 2013; 57(2): 468-75.
    • (2013) Bone , vol.57 , Issue.2 , pp. 468-475
    • Ko, J.Y.1    Chuang, P.C.2    Chen, M.W.3
  • 123
    • 84873659056 scopus 로고    scopus 로고
    • miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells
    • Li H, Li T, Wang S, et al. miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells. Stem Cell Res 2013; 10(3): 313-24.
    • (2013) Stem Cell Res , vol.10 , Issue.3 , pp. 313-324
    • Li, H.1    Li, T.2    Wang, S.3
  • 124
    • 59849099675 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways
    • de Jesus Perez VA, Alastalo TP, Wu JC, et al. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol 2009; 184(1): 83-99.
    • (2009) J Cell Biol , vol.184 , Issue.1 , pp. 83-99
    • de Jesus Perez, V.A.1    Alastalo, T.P.2    Wu, J.C.3
  • 125
    • 84862278575 scopus 로고    scopus 로고
    • Wnt5a signaling is a substantial constituent in bone morphogenetic protein-2-mediated osteoblastogenesis
    • Nemoto E, Ebe Y, Kanaya S, et al. Wnt5a signaling is a substantial constituent in bone morphogenetic protein-2-mediated osteoblastogenesis. Biochem Biophys Res Commun 2012; 422(4): 627-32.
    • (2012) Biochem Biophys Res Commun , vol.422 , Issue.4 , pp. 627-632
    • Nemoto, E.1    Ebe, Y.2    Kanaya, S.3
  • 126
    • 84883400075 scopus 로고    scopus 로고
    • miR-346 regulates osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the Wnt/beta-catenin pathway
    • Wang Q, Cai J, Cai XH, et al. miR-346 regulates osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the Wnt/beta-catenin pathway. PLoS One 2013; 8(9): e72266.
    • (2013) PLoS One , vol.8 , Issue.9
    • Wang, Q.1    Cai, J.2    Cai, X.H.3
  • 127
    • 79960633240 scopus 로고    scopus 로고
    • Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1
    • Zhang J, Tu Q, Bonewald LF, et al. Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1. J Bone Miner Res 2011; 26(8): 1953-63.
    • (2011) J Bone Miner Res , vol.26 , Issue.8 , pp. 1953-1963
    • Zhang, J.1    Tu, Q.2    Bonewald, L.F.3
  • 128
    • 84893776962 scopus 로고    scopus 로고
    • Canonical Wnt signaling activates miR-34 expression during osteoblastic differentiation
    • Tamura M, Uyama M, Sugiyama Y, et al. Canonical Wnt signaling activates miR-34 expression during osteoblastic differentiation. Mol Med Rep 2013; 8(6): 1807-11.
    • (2013) Mol Med Rep , vol.8 , Issue.6 , pp. 1807-1811
    • Tamura, M.1    Uyama, M.2    Sugiyama, Y.3
  • 129
    • 84871345038 scopus 로고    scopus 로고
    • miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells
    • Hassan MQ, Maeda Y, Taipaleenmaki H, et al. miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells. J Biol Chem 2012; 287(50): 42084-92.
    • (2012) J Biol Chem , vol.287 , Issue.50 , pp. 42084-42092
    • Hassan, M.Q.1    Maeda, Y.2    Taipaleenmaki, H.3


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