-
1
-
-
34250823973
-
Minireview: Targeting the Wnt/β-catenin pathway to regulate bone formation in the adult skeleton
-
17395698 10.1210/en.2007-0270 1:CAS:528:DC%2BD2sXmt1ajtrY%3D
-
Baron R, Rawadi G (2007) Minireview: targeting the Wnt/β-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology 148:2635-2643
-
(2007)
Endocrinology
, vol.148
, pp. 2635-2643
-
-
Baron, R.1
Rawadi, G.2
-
2
-
-
34548306408
-
Mechanisms of anabolic therapies for osteoporosis
-
17761594 10.1056/NEJMra067395 1:CAS:528:DC%2BD2sXpvVylurk%3D
-
Canalis E, Giustina A, Bilezikian JP (2007) Mechanisms of anabolic therapies for osteoporosis. N Engl J Med 357:905-916
-
(2007)
N Engl J Med
, vol.357
, pp. 905-916
-
-
Canalis, E.1
Giustina, A.2
Bilezikian, J.P.3
-
3
-
-
13444302715
-
Sequential roles of Hedgehog and WNT signaling in osteoblast development
-
15576404 10.1242/dev.01564 1:CAS:528:DC%2BD2MXhtVSru70%3D
-
Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F (2005) Sequential roles of Hedgehog and WNT signaling in osteoblast development. Development 132:49-60
-
(2005)
Development
, vol.132
, pp. 49-60
-
-
Hu, H.1
Hilton, M.J.2
Tu, X.3
Yu, K.4
Ornitz, D.M.5
Long, F.6
-
4
-
-
33748768971
-
Distinct roles for Hedgehog and canonical WNT signaling in specification, differentiation and maintenance of osteoblast progenitors
-
16854976 10.1242/dev.02480 1:CAS:528:DC%2BD28XhtVart7zI
-
Rodda SJ, McMahon AP (2006) Distinct roles for Hedgehog and canonical WNT signaling in specification, differentiation and maintenance of osteoblast progenitors. Development 133:3231-3234
-
(2006)
Development
, vol.133
, pp. 3231-3234
-
-
Rodda, S.J.1
McMahon, A.P.2
-
5
-
-
17844372752
-
WNT/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
-
15866164 10.1016/j.devcel.2005.03.016 1:CAS:528:DC%2BD2MXkslentbc%3D
-
Day TF, Guo X, Garrett-Beal L, Yang Y (2005) WNT/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell 8:739-750
-
(2005)
Dev Cell
, vol.8
, pp. 739-750
-
-
Day, T.F.1
Guo, X.2
Garrett-Beal, L.3
Yang, Y.4
-
6
-
-
17844363974
-
Canonical Wnt/betacatenin signaling prevents osteoblasts from differentiating into chondrocytes
-
15866163 10.1016/j.devcel.2005.02.013 1:CAS:528:DC%2BD2MXkslentbY%3D
-
Hill TP, Später D, Taketo MM, Birchmeier W, Hartmann C (2005) Canonical Wnt/betacatenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell 8:727-738
-
(2005)
Dev Cell
, vol.8
, pp. 727-738
-
-
Hill, T.P.1
Später, D.2
Taketo, M.M.3
Birchmeier, W.4
Hartmann, C.5
-
7
-
-
33748748473
-
Thiazolidinedione use and bone loss in older diabetic adults
-
16608888 10.1210/jc.2005-2226 1:CAS:528:DC%2BD28Xpslajt74%3D
-
Schwartz AV, Sellmeyer DE, Vittinghoff E, Palermo L, Lecka-Czernik B, Feingold KR, Strotmeyer ES, Resnick HE, Carbone L, Beamer BA, Park SW, Lane NE, Harris TB, Cummings SR (2006) Thiazolidinedione use and bone loss in older diabetic adults. J Clin Endocrinol Metab 91:3349-3354
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 3349-3354
-
-
Schwartz, A.V.1
Sellmeyer, D.E.2
Vittinghoff, E.3
Palermo, L.4
Lecka-Czernik, B.5
Feingold, K.R.6
Strotmeyer, E.S.7
Resnick, H.E.8
Carbone, L.9
Beamer, B.A.10
Park, S.W.11
Lane, N.E.12
Harris, T.B.13
Cummings, S.R.14
-
8
-
-
35748960839
-
A histone lysine methyltransferase activated by non-canonical WNT signalig suppresses PPAr-gamma transactivation
-
17952062 10.1038/ncb1647 1:CAS:528:DC%2BD2sXht1Cgu7fM
-
Takada I, Mihara M, Suzawa M, Ohtake F, Kobayashi S, Igarashi M, Youn MY, Takeyama K, Nakamura T, Mezaki Y, Takezawa S, Yogiashi Y, Kitagawa H, Yamada G, Takada S, Minami Y, Shibuya H, Matsumoto K, Kato S (2007) A histone lysine methyltransferase activated by non-canonical WNT signalig suppresses PPAr-gamma transactivation. Nat Cell Biol 9:1273-1285
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1273-1285
-
-
Takada, I.1
Mihara, M.2
Suzawa, M.3
Ohtake, F.4
Kobayashi, S.5
Igarashi, M.6
Youn, M.Y.7
Takeyama, K.8
Nakamura, T.9
Mezaki, Y.10
Takezawa, S.11
Yogiashi, Y.12
Kitagawa, H.13
Yamada, G.14
Takada, S.15
Minami, Y.16
Shibuya, H.17
Matsumoto, K.18
Kato, S.19
-
9
-
-
14744275847
-
Regulation of osteoblastogenesis and bone mass by WNT10b
-
15728361 10.1073/pnas.0408742102 1:CAS:528:DC%2BD2MXitl2ltbs%3D
-
Bennett CN, Longo KA, Wright WS, Suva LJ, Lane TF, Hankenson KD, MacDougald OA (2005) Regulation of osteoblastogenesis and bone mass by WNT10b. Proc Natl Acad Sci USA 102:3324-3329
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3324-3329
-
-
Bennett, C.N.1
Longo, K.A.2
Wright, W.S.3
Suva, L.J.4
Lane, T.F.5
Hankenson, K.D.6
Macdougald, O.A.7
-
10
-
-
33646808104
-
Wnt signalig in osteoblasts regulates expression of the receptor activator of NFkappaB ligand and inhibits osteoclastogenesis in vitro
-
16522681 10.1242/jcs.02883 1:CAS:528:DC%2BD28Xks1Wjtrw%3D
-
Spencer GJ, Utting JC, Etheridge SL, Arnett TR, Genever PG (2006) Wnt signalig in osteoblasts regulates expression of the receptor activator of NFkappaB ligand and inhibits osteoclastogenesis in vitro. J Cell Sci 119:1283-1296
-
(2006)
J Cell Sci
, vol.119
, pp. 1283-1296
-
-
Spencer, G.J.1
Utting, J.C.2
Etheridge, S.L.3
Arnett, T.R.4
Genever, P.G.5
-
11
-
-
20244373613
-
Canonical WNT signaling in differentiated osteoblasts controls osteoclast differentiation
-
15866165 10.1016/j.devcel.2005.02.017 1:CAS:528:DC%2BD2MXkslenur4%3D
-
Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G (2005) Canonical WNT signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell 8:751-764
-
(2005)
Dev Cell
, vol.8
, pp. 751-764
-
-
Glass II, D.A.1
Bialek, P.2
Ahn, J.D.3
Starbuck, M.4
Patel, M.S.5
Clevers, H.6
Taketo, M.M.7
Long, F.8
McMahon, A.P.9
Lang, R.A.10
Karsenty, G.11
-
12
-
-
77952771209
-
Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss
-
20305005 10.1210/jc.2010-0067 1:CAS:528:DC%2BC3cXmtFegu7Y%3D
-
Gaudio A, Pennisi P, Bratengeier C, Torrisi V, Lindner B, Mangiafico RA, Pulvirenti I, Hawa G, Tringali G, Fiore CE (2010) Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss. J Clin Endocrinol Metab 95:2248-2253
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 2248-2253
-
-
Gaudio, A.1
Pennisi, P.2
Bratengeier, C.3
Torrisi, V.4
Lindner, B.5
Mangiafico, R.A.6
Pulvirenti, I.7
Hawa, G.8
Tringali, G.9
Fiore, C.E.10
-
13
-
-
84866174959
-
Serum sclerostin increases in healthy adult men during bed rest
-
22767636 10.1210/jc.2012-1579 1:CAS:528:DC%2BC38XhtlylsrrK
-
Spatz JM, Fields EE, Yu EW, Divieti Pajevic P, Bouxsein ML, Sibonga JD, Zwart SR, Smith SM (2012) Serum sclerostin increases in healthy adult men during bed rest. J Clin Endocrinol Metab 97:E1736-E1740
-
(2012)
J Clin Endocrinol Metab
, vol.97
-
-
Spatz, J.M.1
Fields, E.E.2
Yu, E.W.3
Divieti Pajevic, P.4
Bouxsein, M.L.5
Sibonga, J.D.6
Zwart, S.R.7
Smith, S.M.8
-
14
-
-
81855184668
-
Determinants of serum sclerostin in healthy pre- and postmenopausal women
-
10.1002/jbmr.479 1:CAS:528:DC%2BC38Xms1yr
-
Ardawi MS, Al-Kadi HA, Rouzi AA, Qari MH (2011) Determinants of serum sclerostin in healthy pre- and postmenopausal women. J Bone Mineral Res 26:2812-2822
-
(2011)
J Bone Mineral Res
, vol.26
, pp. 2812-2822
-
-
Ardawi, M.S.1
Al-Kadi, H.A.2
Rouzi, A.A.3
Qari, M.H.4
-
15
-
-
84855474270
-
Sclerostin and its association with physical activity, age, gender, body composition, and bone mineral content in healthy adults
-
21994959 10.1210/jc.2011-2152 1:CAS:528:DC%2BC38XhsVKru7c%3D
-
Amrein K, Amrein S, Drexler C, Dimai HP, Dobnig H, Pfeifer K, Tomaschitz A, Pieber TR, Fahrleitner-Pammer A (2012) Sclerostin and its association with physical activity, age, gender, body composition, and bone mineral content in healthy adults. J Clin Endocrinol Metab 97:148-154
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 148-154
-
-
Amrein, K.1
Amrein, S.2
Drexler, C.3
Dimai, H.P.4
Dobnig, H.5
Pfeifer, K.6
Tomaschitz, A.7
Pieber, T.R.8
Fahrleitner-Pammer, A.9
-
16
-
-
84860128591
-
Serum sclerostin levels were positively correlated with fat mass and bone mineral density in central south Chinese postmenopausal women
-
10.1111/j.1365-2265.2011.04315.x 1:CAS:528:DC%2BC38XhtVOmtbnF
-
Sheng Z, Tong D, Ou Y, Zhang H, Zhang Z, Li S, Zhou J, Zhang J, Liao E (2012) Serum sclerostin levels were positively correlated with fat mass and bone mineral density in central south Chinese postmenopausal women. Clin Endocrinol 76:797-801
-
(2012)
Clin Endocrinol
, vol.76
, pp. 797-801
-
-
Sheng, Z.1
Tong, D.2
Ou, Y.3
Zhang, H.4
Zhang, Z.5
Li, S.6
Zhou, J.7
Zhang, J.8
Liao, E.9
-
17
-
-
84855493734
-
Circulating levels of sclerostin are increased in patients with type 2 diabetes mellitus
-
22031520 10.1210/jc.2011-2186
-
García-Martín A, Rozas-Moreno P, Reyes-García R, Morales-Santana S, García-Fontana B, García-Salcedo JA, Muñoz-Torres M (2012) Circulating levels of sclerostin are increased in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 97:234-241
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 234-241
-
-
García-Martín, A.1
Rozas-Moreno, P.2
Reyes-García, R.3
Morales-Santana, S.4
García-Fontana, B.5
García-Salcedo, J.A.6
Muñoz-Torres, M.7
-
18
-
-
79951820514
-
Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing
-
21347301 10.1371/journal.pone.0016947 1:CAS:528:DC%2BC3MXisFSnu7Y%3D
-
Caetano-Lopes J, Lopes A, Rodrigues A, Fernandes D, Perpétuo IP, Monjardino T, Lucas R, Monteiro J, Konttinen YT, Canhão H, Fonseca JE (2011) Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing. PLoS ONE 6:e16947
-
(2011)
PLoS ONE
, vol.6
, pp. 16947
-
-
Caetano-Lopes, J.1
Lopes, A.2
Rodrigues, A.3
Fernandes, D.4
Perpétuo, I.P.5
Monjardino, T.6
Lucas, R.7
Monteiro, J.8
Konttinen, Y.T.9
Canhão, H.10
Fonseca, J.E.11
-
19
-
-
84863607640
-
Decreased serum sclerostin levels in patients with primary hyperparathyroidism: A cross-sectional and a longitudinal study
-
22041864 10.1007/s00198-011-1806-8 1:CAS:528:DC%2BC38Xnt12msL0%3D
-
Ardawi MS, Al-Sibiany AM, Bakhsh TM, Rouzi AA, Qari MH (2012) Decreased serum sclerostin levels in patients with primary hyperparathyroidism: a cross-sectional and a longitudinal study. Osteoporos Int 23:1789-1797
-
(2012)
Osteoporos Int
, vol.23
, pp. 1789-1797
-
-
Ardawi, M.S.1
Al-Sibiany, A.M.2
Bakhsh, T.M.3
Rouzi, A.A.4
Qari, M.H.5
-
20
-
-
77957838571
-
Patients with primary hyperparathyroidism have lower circulating levels than euparathyroid controls
-
20817762 10.1530/EJE-10-0699
-
van Lierop AH, Witteveen JE, Hamdy NAT, Papapoulos SE (2010) Patients with primary hyperparathyroidism have lower circulating levels than euparathyroid controls. Eur J Endocrinol 163:833-837
-
(2010)
Eur J Endocrinol
, vol.163
, pp. 833-837
-
-
Van Lierop, A.H.1
Witteveen, J.E.2
Hamdy, N.A.T.3
Papapoulos, S.E.4
-
21
-
-
84876680589
-
Sclerostin and DKK1 in primary hyperparathyroidism
-
23430197 10.1007/s00223-012-9665-7 1:CAS:528:DC%2BC3sXjsleit7g%3D
-
Viapiana O, Fracassi E, Troplini S, Idolazzi L, Rossini M, Adami S, Gatti D (2013) Sclerostin and DKK1 in primary hyperparathyroidism. Calcif Tissue Int 92:324-329
-
(2013)
Calcif Tissue Int
, vol.92
, pp. 324-329
-
-
Viapiana, O.1
Fracassi, E.2
Troplini, S.3
Idolazzi, L.4
Rossini, M.5
Adami, S.6
Gatti, D.7
-
22
-
-
79955552110
-
Sclerostin and Dickkopf-1 in renal osteodystrophy
-
21164019 10.2215/CJN.06550810 1:CAS:528:DC%2BC3MXmt1Ort7w%3D
-
Cejka D, Herberth J, Branscum AJ, Fardo DW, Monier-Faugere MC, Diarra D, Haas M, Malluche HH (2011) Sclerostin and Dickkopf-1 in renal osteodystrophy. Clin J Am Soc Nephrol 6:877-882
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 877-882
-
-
Cejka, D.1
Herberth, J.2
Branscum, A.J.3
Fardo, D.W.4
Monier-Faugere, M.C.5
Diarra, D.6
Haas, M.7
Malluche, H.H.8
-
23
-
-
3242664450
-
Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts
-
15268896 10.1016/j.bone.2004.04.019 1:CAS:528:DC%2BD2cXmtVWit70%3D
-
Sutherland MK, Geoghegan JC, Yu C, Winkler DG, Latham JA (2004) Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts. Bone 35:448-454
-
(2004)
Bone
, vol.35
, pp. 448-454
-
-
Sutherland, M.K.1
Geoghegan, J.C.2
Yu, C.3
Winkler, D.G.4
Latham, J.A.5
-
24
-
-
55849147355
-
Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization
-
18975341 10.1002/art.23954 1:CAS:528:DC%2BD1cXhsV2hs7bJ
-
Yao W, Cheng Z, Pham A, Busse C, Zimmermann EA, Ritchie RO, Lane NE (2008) Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization. Arthritis Rheum 58:3485-3497
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3485-3497
-
-
Yao, W.1
Cheng, Z.2
Pham, A.3
Busse, C.4
Zimmermann, E.A.5
Ritchie, R.O.6
Lane, N.E.7
-
25
-
-
84867275947
-
Circulating sclerostin levels are decreased in patients with endogenous hypercortisolism and increase after treatment
-
22844062 10.1210/jc.2012-2218
-
van Lierop AH, van der Eerden AW, Hamdy NA, Hermus AR, den Heijer M, Papapoulos SE (2012) Circulating sclerostin levels are decreased in patients with endogenous hypercortisolism and increase after treatment. J Clin Endocrinol Metab 97:E1953-E1957
-
(2012)
J Clin Endocrinol Metab
, vol.97
-
-
Van Lierop, A.H.1
Van Der Eerden, A.W.2
Hamdy, N.A.3
Hermus, A.R.4
Den Heijer, M.5
Papapoulos, S.E.6
-
26
-
-
84895073057
-
Osteocyte apoptosis induced by glucocorticoids is prevented and reversed by anti-sclerostin antibody in a male rat model
-
Achiou Z (2012) Osteocyte apoptosis induced by glucocorticoids is prevented and reversed by anti-sclerostin antibody in a male rat model. J Bone Mineral Res 27:s467
-
(2012)
J Bone Mineral Res
, vol.27
, pp. 467
-
-
Achiou, Z.1
-
27
-
-
77951644377
-
Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women
-
20156921 10.1210/jc.2009-2283
-
Mirza FS, Padhi ID, Raisz LG, Lorenzo JA (2010) Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women. J Clin Endocrinol Metab 95:1991-1997
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 1991-1997
-
-
Mirza, F.S.1
Padhi, I.D.2
Raisz, L.G.3
Lorenzo, J.A.4
-
28
-
-
79958770416
-
Effects of estrogen on osteoprogenitor cells and cytokines/bone- regulatory factors in postmenopausal women
-
21550429 10.1016/j.bone.2011.04.015
-
Mödder UI, Roforth MM, Hoey K, McCready LK, Peterson JM, Monroe DG, Oursler MJ, Khosla S (2011) Effects of estrogen on osteoprogenitor cells and cytokines/bone-regulatory factors in postmenopausal women. Bone 49:202-207
-
(2011)
Bone
, vol.49
, pp. 202-207
-
-
Mödder, U.I.1
Roforth, M.M.2
Hoey, K.3
McCready, L.K.4
Peterson, J.M.5
Monroe, D.G.6
Oursler, M.J.7
Khosla, S.8
-
29
-
-
33748156090
-
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
-
16730481 10.1016/j.bone.2006.03.017 1:CAS:528:DC%2BD28XpsVOhtL4%3D
-
Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, Kostenuik P, Lacey DL, Simonet WS, Bolon B, Qian X, Shalhoub V, Ominsky MS, Zhu Ke H, Li X, Richards WG (2006) Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone 39:754-766
-
(2006)
Bone
, vol.39
, pp. 754-766
-
-
Li, J.1
Sarosi, I.2
Cattley, R.C.3
Pretorius, J.4
Asuncion, F.5
Grisanti, M.6
Morony, S.7
Adamu, S.8
Geng, Z.9
Qiu, W.10
Kostenuik, P.11
Lacey, D.L.12
Simonet, W.S.13
Bolon, B.14
Qian, X.15
Shalhoub, V.16
Ominsky, M.S.17
Zhu Ke, H.18
Li, X.19
Richards, W.G.20
more..
-
30
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
14695408 10.1056/NEJMoa030847 1:CAS:528:DC%2BD3sXhtVWit7zO
-
Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, Barlogie B, Shaughnessy JD Jr (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349:2483-2494
-
(2003)
N Engl J Med
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
Rasmussen, E.4
Ma, Y.5
Barlogie, B.6
Shaughnessy, Jr.J.D.7
-
31
-
-
33846949349
-
Dickkopf-1 is a master regulator of joint remodeling
-
17237793 10.1038/nm1538 1:CAS:528:DC%2BD2sXhsVyktbY%3D
-
Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G (2007) Dickkopf-1 is a master regulator of joint remodeling. Nat Med 13:156-163
-
(2007)
Nat Med
, vol.13
, pp. 156-163
-
-
Diarra, D.1
Stolina, M.2
Polzer, K.3
Zwerina, J.4
Ominsky, M.S.5
Dwyer, D.6
Korb, A.7
Smolen, J.8
Hoffmann, M.9
Scheinecker, C.10
Van Der Heide, D.11
Landewe, R.12
Lacey, D.13
Richards, W.G.14
Schett, G.15
-
32
-
-
79955567265
-
Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis
-
21362762 10.3899/jrheum.100089 1:CAS:528:DC%2BC3MXnvVeisbc%3D
-
Wang SY, Liu YY, Ye H, Guo JP, Li R, Liu X, Li ZG (2011) Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis. J Rheumatol 38:821-827
-
(2011)
J Rheumatol
, vol.38
, pp. 821-827
-
-
Wang, S.Y.1
Liu, Y.Y.2
Ye, H.3
Guo, J.P.4
Li, R.5
Liu, X.6
Li, Z.G.7
-
33
-
-
79957814818
-
Relationship of focal erosions, bone mineral density, and parathyroid hormone in rheumatoid arthritis
-
21459948 10.3899/jrheum.100829 1:CAS:528:DC%2BC3MXptVOqur8%3D
-
Rossini M, Bagnato G, Frediani B, Iagnocco A, La Montagna G, Minisola G, Caminiti M, Varenna M, Adami S (2011) Relationship of focal erosions, bone mineral density, and parathyroid hormone in rheumatoid arthritis. J Rheumatol 38:997-1002
-
(2011)
J Rheumatol
, vol.38
, pp. 997-1002
-
-
Rossini, M.1
Bagnato, G.2
Frediani, B.3
Iagnocco, A.4
La Montagna, G.5
Minisola, G.6
Caminiti, M.7
Varenna, M.8
Adami, S.9
-
34
-
-
84895075929
-
Correlation between serum levels of parathyroid hormone and dickkopf-1 in patients with rheumatoid arthritis
-
Orsolini G, Povino MR, Tripi G, Caimmi C, Lippolis I, Idolazzi L, Fracassi E, Viapiana O, Gatti D, Rossini M, Adami S (2012) Correlation between serum levels of parathyroid hormone and dickkopf-1 in patients with rheumatoid arthritis. Ann Rheum Dis 71(Suppl 3):654
-
(2012)
Ann Rheum Dis
, vol.71
, Issue.SUPPL. 3
, pp. 654
-
-
Orsolini, G.1
Povino, M.R.2
Tripi, G.3
Caimmi, C.4
Lippolis, I.5
Idolazzi, L.6
Fracassi, E.7
Viapiana, O.8
Gatti, D.9
Rossini, M.10
Adami, S.11
-
35
-
-
84857910076
-
High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis
-
22186710 10.1136/annrheumdis-2011-200216 1:CAS:528:DC%2BC38XnsFGjs78%3D
-
Heiland GR, Appel H, Poddubnyy D, Zwerina J, Hueber A, Haibel H, Baraliakos X, Listing J, Rudwaleit M, Schett G, Sieper J (2012) High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis. Ann Rheum Dis 71:572-574
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 572-574
-
-
Heiland, G.R.1
Appel, H.2
Poddubnyy, D.3
Zwerina, J.4
Hueber, A.5
Haibel, H.6
Baraliakos, X.7
Listing, J.8
Rudwaleit, M.9
Schett, G.10
Sieper, J.11
-
36
-
-
35348917781
-
Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women
-
17907185 10.1002/art.22867 1:CAS:528:DC%2BD2sXht12rtLbM
-
Lane NE, Nevitt MS, Lui LY, de Leon P, Corr M (2007) Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women. Arthritis Rheum 56:3319-3325
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3319-3325
-
-
Lane, N.E.1
Nevitt, M.S.2
Lui, L.Y.3
De Leon, P.4
Corr, M.5
-
37
-
-
82955180949
-
Low circulating Dickkopf-1 and its link with severity of spinaln involvement in diffuse idiopathic skeletal hyperostosis
-
21900287 10.1136/annrheumdis-2011-200357 1:CAS:528:DC%2BC38Xhs1yitbc%3D
-
Senolt L, Hulejova H, Krystufkova O, Forejtova S, Andres Cerezo L, Gatterova J, Pavelka K, Vencovsky J (2012) Low circulating Dickkopf-1 and its link with severity of spinaln involvement in diffuse idiopathic skeletal hyperostosis. Ann Rheum Dis 71:71-74
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 71-74
-
-
Senolt, L.1
Hulejova, H.2
Krystufkova, O.3
Forejtova, S.4
Andres Cerezo, L.5
Gatterova, J.6
Pavelka, K.7
Vencovsky, J.8
-
38
-
-
18044386744
-
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
-
11719191 10.1016/S0092-8674(01)00571-2 1:CAS:528:DC%2BD3MXovVCnsb4%3D
-
Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reginato AM, Wang H, Cundy T, Glorieux FH, Lev D, Zacharin M, Oexle K, Marcelino J, Suwairi W, Heeger S, Sabatakos G, Apte S, Adkins WN, Allgrove J, Arslan-Kirchner M, Batch JA, Beighton P, Black GC, Boles RG, Boon LM, Borrone C, Brunner HG, Carle GF, Dallapiccola B, De Paepe A, Floege B, Halfhide ML, Hall B, Hennekam RC, Hirose T, Jans A, Jüppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A, LaCombe D, Lambert M, Lemyre E, Letteboer T, Peltonen L, Ramesar RS, Romanengo M, Somer H, Steichen-Gersdorf E, Steinmann B, Sullivan B, Superti-Furga A, Swoboda W, van den Boogaard MJ, Van Hul W, Vikkula M, Votruba M, Zabel B, Garcia T, Baron R, Olsen BR, Warman ML (2001) LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107:513-523
-
(2001)
Cell
, vol.107
, pp. 513-523
-
-
Gong, Y.1
Slee, R.B.2
Fukai, N.3
Rawadi, G.4
Roman-Roman, S.5
Reginato, A.M.6
Wang, H.7
Cundy, T.8
Glorieux, F.H.9
Lev, D.10
Zacharin, M.11
Oexle, K.12
Marcelino, J.13
Suwairi, W.14
Heeger, S.15
Sabatakos, G.16
Apte, S.17
Adkins, W.N.18
Allgrove, J.19
Arslan-Kirchner, M.20
Batch, J.A.21
Beighton, P.22
Black, G.C.23
Boles, R.G.24
Boon, L.M.25
Borrone, C.26
Brunner, H.G.27
Carle, G.F.28
Dallapiccola, B.29
De Paepe, A.30
Floege, B.31
Halfhide, M.L.32
Hall, B.33
Hennekam, R.C.34
Hirose, T.35
Jans, A.36
Jüppner, H.37
Kim, C.A.38
Keppler-Noreuil, K.39
Kohlschuetter, A.40
Lacombe, D.41
Lambert, M.42
Lemyre, E.43
Letteboer, T.44
Peltonen, L.45
Ramesar, R.S.46
Romanengo, M.47
Somer, H.48
Steichen-Gersdorf, E.49
Steinmann, B.50
Sullivan, B.51
Superti-Furga, A.52
Swoboda, W.53
Van Den Boogaard, M.J.54
Van Hul, W.55
Vikkula, M.56
Votruba, M.57
Zabel, B.58
Garcia, T.59
Baron, R.60
Olsen, B.R.61
Warman, M.L.62
more..
-
39
-
-
0037118285
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
12015390 10.1056/NEJMoa013444 1:CAS:528:DC%2BD38Xjs1Smurs%3D
-
Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, Mitnick MA, Wu D, Insogna K, Lifton RP (2002) High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 346:1513-1521
-
(2002)
N Engl J Med
, vol.346
, pp. 1513-1521
-
-
Boyden, L.M.1
Mao, J.2
Belsky, J.3
Mitzner, L.4
Farhi, A.5
Mitnick, M.A.6
Wu, D.7
Insogna, K.8
Lifton, R.P.9
-
40
-
-
0036138175
-
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
-
11741193 10.1086/338450 1:CAS:528:DC%2BD38XlvVKhtw%3D%3D
-
Little RD, Carulli JP, Del Mastro RG, Dupuis J, Osborne M, Folz C, Manning SP, Swain PM, Zhao SC, Eustace B, Lappe MM, Spitzer L, Zweier S, Braunschweiger K, Benchekroun Y, Hu X, Adair R, Chee L, FitzGerald MG, Tulig C, Caruso A, Tzellas N, Bawa A, Franklin B, McGuire S, Nogues X, Gong G, Allen KM, Anisowicz A, Morales AJ, Lomedico PT, Recker SM, Van Eerdewegh P, Recker RR, Johnson ML (2002) A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet 70:11-19
-
(2002)
Am J Hum Genet
, vol.70
, pp. 11-19
-
-
Little, R.D.1
Carulli, J.P.2
Del Mastro, R.G.3
Dupuis, J.4
Osborne, M.5
Folz, C.6
Manning, S.P.7
Swain, P.M.8
Zhao, S.C.9
Eustace, B.10
Lappe, M.M.11
Spitzer, L.12
Zweier, S.13
Braunschweiger, K.14
Benchekroun, Y.15
Hu, X.16
Adair, R.17
Chee, L.18
Fitzgerald, M.G.19
Tulig, C.20
Caruso, A.21
Tzellas, N.22
Bawa, A.23
Franklin, B.24
McGuire, S.25
Nogues, X.26
Gong, G.27
Allen, K.M.28
Anisowicz, A.29
Morales, A.J.30
Lomedico, P.T.31
Recker, S.M.32
Van Eerdewegh, P.33
Recker, R.R.34
Johnson, M.L.35
more..
-
41
-
-
2442656675
-
The LRP5 high-bone-mass G171 v mutation disrupts LRP5 interaction with Mesd
-
15143163 10.1128/MCB.24.11.4677-4684.2004 1:CAS:528:DC%2BD2cXksVyhsrc%3D
-
Zhang Y, Wang Y, Li X, Zhang J, Mao J, Li Z, Zheng J, Li L, Harris S, Wu D (2004) The LRP5 high-bone-mass G171 V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol 24:4677-4684
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4677-4684
-
-
Zhang, Y.1
Wang, Y.2
Li, X.3
Zhang, J.4
Mao, J.5
Li, Z.6
Zheng, J.7
Li, L.8
Harris, S.9
Wu, D.10
-
42
-
-
33846449190
-
Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity
-
17002572 10.1359/jbmr.060810 1:CAS:528:DC%2BD28Xht1ert7vL
-
Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R (2006) Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res 21:1738-1749
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1738-1749
-
-
Ellies, D.L.1
Viviano, B.2
McCarthy, J.3
Rey, J.P.4
Itasaki, N.5
Saunders, S.6
Krumlauf, R.7
-
43
-
-
2342529785
-
Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites
-
15077203 10.1086/420771 1:CAS:528:DC%2BD2cXjvVeis7k%3D
-
Ferrari SL, Deutsch S, Choudhury U, Chevalley T, Bonjour JP, Dermitzakis ET, Rizzoli R, Antonarakis SE (2004) Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites. Am J Hum Genet 74:866-875
-
(2004)
Am J Hum Genet
, vol.74
, pp. 866-875
-
-
Ferrari, S.L.1
Deutsch, S.2
Choudhury, U.3
Chevalley, T.4
Bonjour, J.P.5
Dermitzakis, E.T.6
Rizzoli, R.7
Antonarakis, S.E.8
-
44
-
-
0035089781
-
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein
-
11179006 10.1086/318811 1:CAS:528:DC%2BD3MXit1altbk%3D
-
Brunkow ME, Gardner JC, Van Ness J, Paeper BW, Kovacevich BR, Proll S, Skonier JE, Zhao L, Sabo PJ, Fu Y, Alisch RS, Gillett L, Colbert T, Tacconi P, Galas D, Hamersma H, Beighton P, Mulligan J (2001) Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Am J Hum Genet 68:577-589
-
(2001)
Am J Hum Genet
, vol.68
, pp. 577-589
-
-
Brunkow, M.E.1
Gardner, J.C.2
Van Ness, J.3
Paeper, B.W.4
Kovacevich, B.R.5
Proll, S.6
Skonier, J.E.7
Zhao, L.8
Sabo, P.J.9
Fu, Y.10
Alisch, R.S.11
Gillett, L.12
Colbert, T.13
Tacconi, P.14
Galas, D.15
Hamersma, H.16
Beighton, P.17
Mulligan, J.18
-
45
-
-
84875343487
-
Van Buchem disease: Clinical, biochemical, and densitometric features of patients and disease carriers
-
23074140 10.1002/jbmr.1794
-
van Lierop AH, Hamdy NA, van Egmond ME, Bakker E, Dikkers FG, Papapoulos SE (2013) Van Buchem disease: clinical, biochemical, and densitometric features of patients and disease carriers. J Bone Miner Res 28:848-854
-
(2013)
J Bone Miner Res
, vol.28
, pp. 848-854
-
-
Van Lierop, A.H.1
Hamdy, N.A.2
Van Egmond, M.E.3
Bakker, E.4
Dikkers, F.G.5
Papapoulos, S.E.6
-
46
-
-
0037092049
-
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
-
11956231 10.1083/jcb.200201089 1:CAS:528:DC%2BD38XivFKktLk%3D
-
Kato M, Patel MS, Levasseur R, Lobov I, Chang BH, Glass DA 2nd, Hartmann C, Li L, Hwang TH, Brayton CF, Lang RA, Karsenty G, Chan L (2002) Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol 157:303-314
-
(2002)
J Cell Biol
, vol.157
, pp. 303-314
-
-
Kato, M.1
Patel, M.S.2
Levasseur, R.3
Lobov, I.4
Chang, B.H.5
Glass II, D.A.6
Hartmann, C.7
Li, L.8
Hwang, T.H.9
Brayton, C.F.10
Lang, R.A.11
Karsenty, G.12
Chan, L.13
-
47
-
-
10744224854
-
High bone mass in mice expressing a mutant LRP5 gene
-
12817748 10.1359/jbmr.2003.18.6.960 1:CAS:528:DC%2BD3sXkslOhsLs%3D
-
Babij P, Zhao W, Small C, Kharode Y, Yaworsky PJ, Bouxsein ML, Reddy PS, Bodine PV, Robinson JA, Bhat B, Marzolf J, Moran RA, Bex F (2003) High bone mass in mice expressing a mutant LRP5 gene. J Bone Miner Res 18:960-974
-
(2003)
J Bone Miner Res
, vol.18
, pp. 960-974
-
-
Babij, P.1
Zhao, W.2
Small, C.3
Kharode, Y.4
Yaworsky, P.J.5
Bouxsein, M.L.6
Reddy, P.S.7
Bodine, P.V.8
Robinson, J.A.9
Bhat, B.10
Marzolf, J.11
Moran, R.A.12
Bex, F.13
-
48
-
-
43049181624
-
Bone mineral density, osteoporosis, and osteoporotic fractures: A genome-wide association study
-
18455228 10.1016/S0140-6736(08)60599-1 1:CAS:528:DC%2BD1cXlsFGisr0%3D
-
Richards JB, Rivadeneira F, Inouye M, Pastinen TM, Soranzo N, Wilson SG, Andrew T, Falchi M, Gwilliam R, Ahmadi KR, Valdes AM, Arp P, Whittaker P, Verlaan DJ, Jhamai M, Kumanduri V, Moorhouse M, van Meurs JB, Hofman A, Pols HA, Hart D, Zhai G, Kato BS, Mullin BH, Zhang F, Deloukas P, Uitterlinden AG, Spector TD (2008) Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Lancet 371:1505-1512
-
(2008)
Lancet
, vol.371
, pp. 1505-1512
-
-
Richards, J.B.1
Rivadeneira, F.2
Inouye, M.3
Pastinen, T.M.4
Soranzo, N.5
Wilson, S.G.6
Andrew, T.7
Falchi, M.8
Gwilliam, R.9
Ahmadi, K.R.10
Valdes, A.M.11
Arp, P.12
Whittaker, P.13
Verlaan, D.J.14
Jhamai, M.15
Kumanduri, V.16
Moorhouse, M.17
Van Meurs, J.B.18
Hofman, A.19
Pols, H.A.20
Hart, D.21
Zhai, G.22
Kato, B.S.23
Mullin, B.H.24
Zhang, F.25
Deloukas, P.26
Uitterlinden, A.G.27
Spector, T.D.28
more..
-
49
-
-
40949146531
-
Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis
-
18349089 10.1001/jama.299.11.1277
-
van Meurs JB, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Van Hul W, Agueda L, Akesson K, Benevolenskaya LI, Ferrari SL, Hallmans G, Hofman A, Husted LB, Kruk M, Kaptoge S, Karasik D, Karlsson MK, Lorentzon M, Masi L, McGuigan FE, Mellström D, Mosekilde L, Nogues X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Weber K, Ioannidis JP, Uitterlinden AG (2008) Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA 299:1277-1290
-
(2008)
JAMA
, vol.299
, pp. 1277-1290
-
-
Van Meurs, J.B.1
Trikalinos, T.A.2
Ralston, S.H.3
Balcells, S.4
Brandi, M.L.5
Brixen, K.6
Kiel, D.P.7
Langdahl, B.L.8
Lips, P.9
Ljunggren, O.10
Lorenc, R.11
Obermayer-Pietsch, B.12
Ohlsson, C.13
Pettersson, U.14
Reid, D.M.15
Rousseau, F.16
Scollen, S.17
Van Hul, W.18
Agueda, L.19
Akesson, K.20
Benevolenskaya, L.I.21
Ferrari, S.L.22
Hallmans, G.23
Hofman, A.24
Husted, L.B.25
Kruk, M.26
Kaptoge, S.27
Karasik, D.28
Karlsson, M.K.29
Lorentzon, M.30
Masi, L.31
McGuigan, F.E.32
Mellström, D.33
Mosekilde, L.34
Nogues, X.35
Pols, H.A.36
Reeve, J.37
Renner, W.38
Rivadeneira, F.39
Van Schoor, N.M.40
Weber, K.41
Ioannidis, J.P.42
Uitterlinden, A.G.43
more..
-
50
-
-
8844261126
-
Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites
-
15514891 10.1086/426458 1:CAS:528:DC%2BD2cXhtVegsrnL
-
Uitterlinden AG, Arp PP, Paeper BW, Charmley P, Proll S, Rivadeneira F, Fang Y, van Meurs JB, Britschgi TB, Latham JA, Schatzman RC, Pols HA, Brunkow ME (2004) Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites. Am J Hum Genet 75:1032-1045
-
(2004)
Am J Hum Genet
, vol.75
, pp. 1032-1045
-
-
Uitterlinden, A.G.1
Arp, P.P.2
Paeper, B.W.3
Charmley, P.4
Proll, S.5
Rivadeneira, F.6
Fang, Y.7
Van Meurs, J.B.8
Britschgi, T.B.9
Latham, J.A.10
Schatzman, R.C.11
Pols, H.A.12
Brunkow, M.E.13
-
51
-
-
84863888921
-
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk
-
22792071 10.1371/journal.pgen.1002745 1:CAS:528:DC%2BC38XhtVars73N
-
Zheng HF, Tobias JH, Duncan E, Evans DM, Eriksson J, Paternoster L, Yerges-Armstrong LM, Lehtimäki T, Bergström U, Kähönen M, Leo PJ, Raitakari O, Laaksonen M, Nicholson GC, Viikari J, Ladouceur M, Lyytikäinen LP, Medina-Gomez C, Rivadeneira F, Prince RL, Sievanen H, Leslie WD, Mellström D, Eisman JA, Movérare-Skrtic S, Goltzman D, Hanley DA, Jones G, St Pourcain B, Xiao Y, Timpson NJ, Smith GD, Reid IR, Ring SM, Sambrook PN, Karlsson M, Dennison EM, Kemp JP, Danoy P, Sayers A, Wilson SG, Nethander M, McCloskey E, Vandenput L, Eastell R, Liu J, Spector T, Mitchell BD, Streeten EA, Brommage R, Pettersson-Kymmer U, Brown MA, Ohlsson C, Richards JB, Lorentzon M (2012) WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet 8:e1002745
-
(2012)
PLoS Genet
, vol.8
, pp. 1002745
-
-
Zheng, H.F.1
Tobias, J.H.2
Duncan, E.3
Evans, D.M.4
Eriksson, J.5
Paternoster, L.6
Yerges-Armstrong, L.M.7
Lehtimäki, T.8
Bergström, U.9
Kähönen, M.10
Leo, P.J.11
Raitakari, O.12
Laaksonen, M.13
Nicholson, G.C.14
Viikari, J.15
Ladouceur, M.16
Lyytikäinen, L.P.17
Medina-Gomez, C.18
Rivadeneira, F.19
Prince, R.L.20
Sievanen, H.21
Leslie, W.D.22
Mellström, D.23
Eisman, J.A.24
Movérare-Skrtic, S.25
Goltzman, D.26
Hanley, D.A.27
Jones, G.28
St Pourcain, B.29
Xiao, Y.30
Timpson, N.J.31
Smith, G.D.32
Reid, I.R.33
Ring, S.M.34
Sambrook, P.N.35
Karlsson, M.36
Dennison, E.M.37
Kemp, J.P.38
Danoy, P.39
Sayers, A.40
Wilson, S.G.41
Nethander, M.42
McCloskey, E.43
Vandenput, L.44
Eastell, R.45
Liu, J.46
Spector, T.47
Mitchell, B.D.48
Streeten, E.A.49
Brommage, R.50
Pettersson-Kymmer, U.51
Brown, M.A.52
Ohlsson, C.53
Richards, J.B.54
Lorentzon, M.55
more..
-
52
-
-
84863897868
-
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus
-
22792070 10.1371/journal.pgen.1002718 1:CAS:528:DC%2BC38XhtVars73O
-
Medina-Gomez C, Kemp JP, Estrada K, Eriksson J, Liu J, Reppe S, Evans DM, Heppe DH, Vandenput L, Herrera L, Ring SM, Kruithof CJ, Timpson NJ, Zillikens MC, Olstad OK, Zheng HF, Richards JB, St Pourcain B, Hofman A, Jaddoe VW, Smith GD, Lorentzon M, Gautvik KM, Uitterlinden AG, Brommage R, Ohlsson C, Tobias JH, Rivadeneira F (2012) Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genet 8:e1002718
-
(2012)
PLoS Genet
, vol.8
, pp. 1002718
-
-
Medina-Gomez, C.1
Kemp, J.P.2
Estrada, K.3
Eriksson, J.4
Liu, J.5
Reppe, S.6
Evans, D.M.7
Heppe, D.H.8
Vandenput, L.9
Herrera, L.10
Ring, S.M.11
Kruithof, C.J.12
Timpson, N.J.13
Zillikens, M.C.14
Olstad, O.K.15
Zheng, H.F.16
Richards, J.B.17
St Pourcain, B.18
Hofman, A.19
Jaddoe, V.W.20
Smith, G.D.21
Lorentzon, M.22
Gautvik, K.M.23
Uitterlinden, A.G.24
Brommage, R.25
Ohlsson, C.26
Tobias, J.H.27
Rivadeneira, F.28
more..
-
53
-
-
84860464634
-
Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis
-
22544526 10.1002/art.34526
-
Baker-Lepain JC, Lynch JA, Parimi N, McCulloch CE, Nevitt MC, Corr M, Lane NE (2012) Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis. Arthritis Rheum 64:1457-1465
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1457-1465
-
-
Baker-Lepain, J.C.1
Lynch, J.A.2
Parimi, N.3
McCulloch, C.E.4
Nevitt, M.C.5
Corr, M.6
Lane, N.E.7
-
54
-
-
84861422537
-
Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis
-
22566624 10.1073/pnas.1119899109
-
Castano Betancourt MC, Cailotto F, Kerkhof HJ, Cornelis FM, Doherty SA, Hart DJ, Hofman A, Luyten FP, Maciewicz RA, Mangino M, Metrustry S, Muir K, Peters MJ, Rivadeneira F, Wheeler M, Zhang W, Arden N, Spector TD, Uitterlinden AG, Doherty M, Lories RJ, Valdes AM, van Meurs JB (2012) Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. Proc Natl Acad Sci USA 109:8218-8223
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 8218-8223
-
-
Castano Betancourt, M.C.1
Cailotto, F.2
Kerkhof, H.J.3
Cornelis, F.M.4
Doherty, S.A.5
Hart, D.J.6
Hofman, A.7
Luyten, F.P.8
Maciewicz, R.A.9
Mangino, M.10
Metrustry, S.11
Muir, K.12
Peters, M.J.13
Rivadeneira, F.14
Wheeler, M.15
Zhang, W.16
Arden, N.17
Spector, T.D.18
Uitterlinden, A.G.19
Doherty, M.20
Lories, R.J.21
Valdes, A.M.22
Van Meurs, J.B.23
more..
-
55
-
-
84880917933
-
Wnt signalling and the genetics of osteoarthritis
-
10.1038/bonekey.2012.220
-
Tobias JH (2012) Wnt signalling and the genetics of osteoarthritis. IBMS BoneKEy 9:220
-
(2012)
IBMS BoneKEy
, vol.9
, pp. 220
-
-
Tobias, J.H.1
-
56
-
-
77957846460
-
Relation of age, gender, and bone mass to circulating sclerostin levels in women and men
-
20721932 10.1002/jbmr.217
-
Mödder UI, Hoey KA, Amin S, McCready LK, Achenbach SJ, Riggs BL, Melton LJ 3rd, Khosla S (2011) Relation of age, gender, and bone mass to circulating sclerostin levels in women and men. J Bone Miner Res 26:373-379
-
(2011)
J Bone Miner Res
, vol.26
, pp. 373-379
-
-
Mödder, U.I.1
Hoey, K.A.2
Amin, S.3
McCready, L.K.4
Achenbach, S.J.5
Riggs, B.L.6
Melton III, L.J.7
Khosla, S.8
-
57
-
-
33846026749
-
Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone
-
16908522 10.1074/jbc.M602308200 1:CAS:528:DC%2BD28XhtVOrtr3F
-
Robinson JA, Chatterjee-Kishore M, Yaworsky PJ, Cullen DM, Zhao W, Li C, Kharode Y, Sauter L, Babij P, Brown EL, Hill AA, Akhter MP, Johnson ML, Recker RR, Komm BS, Bex FJ (2006) Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone. J Biol Chem 281:31720-31728
-
(2006)
J Biol Chem
, vol.281
, pp. 31720-31728
-
-
Robinson, J.A.1
Chatterjee-Kishore, M.2
Yaworsky, P.J.3
Cullen, D.M.4
Zhao, W.5
Li, C.6
Kharode, Y.7
Sauter, L.8
Babij, P.9
Brown, E.L.10
Hill, A.A.11
Akhter, M.P.12
Johnson, M.L.13
Recker, R.R.14
Komm, B.S.15
Bex, F.J.16
-
58
-
-
84877641819
-
The relation between renal function and serum sclerostin in adult patients with CKD
-
23430206 10.2215/CJN.07670712 1:CAS:528:DC%2BC3sXos1yqsrs%3D
-
Pelletier S, Dubourg L, Carlier MC, Hadj-Aissa A, Fouque D (2013) The relation between renal function and serum sclerostin in adult patients with CKD. Clin J Am Soc Nephrol 8:819-823
-
(2013)
Clin J Am Soc Nephrol
, vol.8
, pp. 819-823
-
-
Pelletier, S.1
Dubourg, L.2
Carlier, M.C.3
Hadj-Aissa, A.4
Fouque, D.5
-
59
-
-
84869390060
-
High serum sclerostin predicts the occurrence of osteoporotic fractures in postmenopausal women: The Center of Excellence for Osteoporosis Research Study
-
10.1002/jbmr.1718 1:CAS:528:DC%2BC38Xhs12ju7bO
-
Ardawi MS, Rouzi AA, Al-Sibiani SA, Al-Senani NS, Qari MH, Mousa SA (2012) High serum sclerostin predicts the occurrence of osteoporotic fractures in postmenopausal women: the Center of Excellence for Osteoporosis Research Study. J Bone Mineral Res 27:2592-2602
-
(2012)
J Bone Mineral Res
, vol.27
, pp. 2592-2602
-
-
Ardawi, M.S.1
Rouzi, A.A.2
Al-Sibiani, S.A.3
Al-Senani, N.S.4
Qari, M.H.5
Mousa, S.A.6
-
60
-
-
84861985326
-
Serum sclerostin and risk of hip fracture in older Caucasian women
-
Study of Osteoporotic Fractures Research Group 22466341 10.1210/jc.2011-3419 1:CAS:528:DC%2BC38Xos1eisr8%3D
-
Arasu A, Cawthon PM, Lui LY, Do TP, Arora PS, Cauley JA, Ensrud KE, Cummings SR, Study of Osteoporotic Fractures Research Group (2012) Serum sclerostin and risk of hip fracture in older Caucasian women. J Clin Endocrinol Metab 97:2027-2032
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 2027-2032
-
-
Arasu, A.1
Cawthon, P.M.2
Lui, L.Y.3
Do, T.P.4
Arora, P.S.5
Cauley, J.A.6
Ensrud, K.E.7
Cummings, S.R.8
-
61
-
-
84875186616
-
Lower fracture risk in older men with higher sclerostin concentration: A prospective analysis from the MINOS study
-
23165952 10.1002/jbmr.1823 1:CAS:528:DC%2BC3sXkt1Ghu7c%3D
-
Szulc P, Bertholon C, Borel O, Marchand F, Chapurlat R (2013) Lower fracture risk in older men with higher sclerostin concentration: a prospective analysis from the MINOS study. J Bone Miner Res 28:855-864
-
(2013)
J Bone Miner Res
, vol.28
, pp. 855-864
-
-
Szulc, P.1
Bertholon, C.2
Borel, O.3
Marchand, F.4
Chapurlat, R.5
-
62
-
-
84857440881
-
Serum sclerostin levels positively correlate with lumbar spinal bone mineral density in postmenopausal women - The 6-month effect of risedronate and teriparatide
-
21305266 10.1007/s00198-010-1525-6 1:CAS:528:DC%2BC38XitlGlurY%3D
-
Polyzos SA, Anastasilakis AD, Bratengeier C, Woloszczuk W, Papatheodorou A, Terpos E (2012) Serum sclerostin levels positively correlate with lumbar spinal bone mineral density in postmenopausal women - the 6-month effect of risedronate and teriparatide. Osteoporos Int 23:1171-1176
-
(2012)
Osteoporos Int
, vol.23
, pp. 1171-1176
-
-
Polyzos, S.A.1
Anastasilakis, A.D.2
Bratengeier, C.3
Woloszczuk, W.4
Papatheodorou, A.5
Terpos, E.6
-
63
-
-
84873726062
-
Association of serum sclerostin with bone mineral density, bone turnover, steroid and parathyroid hormones, and fracture risk in postmenopausal women: The OFELY study
-
22525978 10.1007/s00198-012-1978-x 1:CAS:528:DC%2BC3sXhvVyqs78%3D
-
Garnero P, Sornay-Rendu E, Munoz F, Borel O, Chapurlat RD (2013) Association of serum sclerostin with bone mineral density, bone turnover, steroid and parathyroid hormones, and fracture risk in postmenopausal women: the OFELY study. Osteoporos Int 24:489-494
-
(2013)
Osteoporos Int
, vol.24
, pp. 489-494
-
-
Garnero, P.1
Sornay-Rendu, E.2
Munoz, F.3
Borel, O.4
Chapurlat, R.D.5
-
64
-
-
84861217590
-
Serum sclerostin levels in Paget's disease and prostate cancer with bone metastases with a wide range of bone turnover
-
22579776 10.1016/j.bone.2012.04.016 1:CAS:528:DC%2BC38XotFarurw%3D
-
Yavropoulou MP, van Lierop AH, Hamdy NA, Rizzoli R, Papapoulos SE (2012) Serum sclerostin levels in Paget's disease and prostate cancer with bone metastases with a wide range of bone turnover. Bone 51:153-157
-
(2012)
Bone
, vol.51
, pp. 153-157
-
-
Yavropoulou, M.P.1
Van Lierop, A.H.2
Hamdy, N.A.3
Rizzoli, R.4
Papapoulos, S.E.5
-
65
-
-
78650955673
-
Regulation of circulating sclerostin levels by sex steroids in women and in men
-
10.1002/jbmr.128
-
Mödder UI, Clowes JA, Hoey K, Peterson JM, McCready L, Oursler MJ, Riggs BL, Khosla S (2011) Regulation of circulating sclerostin levels by sex steroids in women and in men. J Bone Mineral Res 26:27-34
-
(2011)
J Bone Mineral Res
, vol.26
, pp. 27-34
-
-
Mödder, U.I.1
Clowes, J.A.2
Hoey, K.3
Peterson, J.M.4
McCready, L.5
Oursler, M.J.6
Riggs, B.L.7
Khosla, S.8
-
66
-
-
84861723097
-
Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women
-
21660558 10.1007/s00198-011-1675-1 1:CAS:528:DC%2BC38XjvVSnt7c%3D
-
Chung YE, Lee SH, Lee SY, Kim SY, Kim HH, Mirza FS, Lee SK, Lorenzo JA, Kim GS, Koh JM (2012) Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women. Osteoporos Int 23:1235-1243
-
(2012)
Osteoporos Int
, vol.23
, pp. 1235-1243
-
-
Chung, Y.E.1
Lee, S.H.2
Lee, S.Y.3
Kim, S.Y.4
Kim, H.H.5
Mirza, F.S.6
Lee, S.K.7
Lorenzo, J.A.8
Kim, G.S.9
Koh, J.M.10
-
67
-
-
84856963771
-
Bisphosphonate treatment of postmenopausal osteoporosis is associated with a dose dependent increase in serum sclerostin
-
22178539 10.1016/j.bone.2011.11.028 1:CAS:528:DC%2BC38Xnt1KltbY%3D
-
Gatti D, Viapiana O, Adami S, Idolazzi L, Fracassi E, Rossini M (2012) Bisphosphonate treatment of postmenopausal osteoporosis is associated with a dose dependent increase in serum sclerostin. Bone 50:739-742
-
(2012)
Bone
, vol.50
, pp. 739-742
-
-
Gatti, D.1
Viapiana, O.2
Adami, S.3
Idolazzi, L.4
Fracassi, E.5
Rossini, M.6
-
68
-
-
58549115903
-
Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate
-
19075223 10.1073/pnas.0805133106 1:CAS:528:DC%2BD1MXks1GksQ%3D%3D
-
Pederson L, Ruan M, Westendorf JJ, Khosla S, Oursler MJ (2008) Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proc Natl Acad Sci USA 105:20764-20769
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20764-20769
-
-
Pederson, L.1
Ruan, M.2
Westendorf, J.J.3
Khosla, S.4
Oursler, M.J.5
-
69
-
-
79954422711
-
Reduced osteoclastogenesis and RANKL expression in marrow from women taking alendronate
-
21327765 10.1007/s00223-011-9473-5 1:CAS:528:DC%2BC3MXjt1Slu7k%3D
-
Eslami B, Zhou S, Van Eekeren I, LeBoff MS, Glowacki J (2011) Reduced osteoclastogenesis and RANKL expression in marrow from women taking alendronate. Calcif Tissue Int 88:272-280
-
(2011)
Calcif Tissue Int
, vol.88
, pp. 272-280
-
-
Eslami, B.1
Zhou, S.2
Van Eekeren, I.3
Leboff, M.S.4
Glowacki, J.5
-
70
-
-
84867504216
-
Sclerostin and DKK1 in postmenopausal osteoporosis treated with denosumab
-
22692843 10.1002/jbmr.1681 1:CAS:528:DC%2BC38XhsFWisLfJ
-
Gatti D, Viapiana O, Fracassi E, Idolazzi L, Dartizio C, Povino MR, Adami S, Rossini M (2012) Sclerostin and DKK1 in postmenopausal osteoporosis treated with denosumab. J Bone Miner Res 27:2259-2263
-
(2012)
J Bone Miner Res
, vol.27
, pp. 2259-2263
-
-
Gatti, D.1
Viapiana, O.2
Fracassi, E.3
Idolazzi, L.4
Dartizio, C.5
Povino, M.R.6
Adami, S.7
Rossini, M.8
-
71
-
-
77957853500
-
Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women
-
20631014 10.1210/jc.2010-0720 1:CAS:528:DC%2BC3cXhsV2nsbnP
-
Drake MT, Srinivasan B, Mödder UI, Peterson JM, McCready LK, Riggs BL, Dwyer D, Stolina M, Kostenuik P, Khosla S (2010) Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab 95:5056-5062
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 5056-5062
-
-
Drake, M.T.1
Srinivasan, B.2
Mödder, U.I.3
Peterson, J.M.4
McCready, L.K.5
Riggs, B.L.6
Dwyer, D.7
Stolina, M.8
Kostenuik, P.9
Khosla, S.10
-
72
-
-
80155124726
-
Acute decline in serum sclerostin in response to PTH infusion in heakthy men
-
21865370 10.1210/jc.2011-1534 1:CAS:528:DC%2BC3MXhsV2nurzK
-
Yu EW, Kumbhani R, Siwila-Sackman E, Leder BZ (2011) Acute decline in serum sclerostin in response to PTH infusion in heakthy men. J Clin Endocrinol Metab 96:E1848-E1851
-
(2011)
J Clin Endocrinol Metab
, vol.96
-
-
Yu, E.W.1
Kumbhani, R.2
Siwila-Sackman, E.3
Leder, B.Z.4
-
73
-
-
84869013738
-
Serum sclerostin levels decline in postmenopausal women with osteoporosis following treatment with intermittent PTH
-
22842667 1:CAS:528:DC%2BC3sXjsFGlsb4%3D
-
Piemonte S, Romagnoli E, Bratengeier C, Woloszczuk W, Tancredi A, Pepe J, Cipriani C, Minisola S (2012) Serum sclerostin levels decline in postmenopausal women with osteoporosis following treatment with intermittent PTH. J Endocrinol Invest 35:866-868
-
(2012)
J Endocrinol Invest
, vol.35
, pp. 866-868
-
-
Piemonte, S.1
Romagnoli, E.2
Bratengeier, C.3
Woloszczuk, W.4
Tancredi, A.5
Pepe, J.6
Cipriani, C.7
Minisola, S.8
-
74
-
-
79955645089
-
The waning of teriparatide effect on bone formation markers in postmenopausal osteoporosis is associated with increasing serum levels of DKK1
-
21367927 10.1210/jc.2010-2552 1:CAS:528:DC%2BC3MXmsVWnsbg%3D
-
Gatti D, Viapiana O, Idolazzi L, Fracassi E, Rossini M, Adami S (2011) The waning of teriparatide effect on bone formation markers in postmenopausal osteoporosis is associated with increasing serum levels of DKK1. J Clin Endocrinol Metab 96:1555-1559
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 1555-1559
-
-
Gatti, D.1
Viapiana, O.2
Idolazzi, L.3
Fracassi, E.4
Rossini, M.5
Adami, S.6
-
75
-
-
79959894497
-
An Akt-dependent increase in canonical Wnt signaling and a decrease in sclerostin protein levels are involved in strontium ranelate-induced osteogenic effects in human osteoblasts
-
21566129 10.1074/jbc.M111.251116 1:CAS:528:DC%2BC3MXot1Gls7o%3D
-
Rybchyn MS, Slater M, Conigrave AD, Mason RS (2011) An Akt-dependent increase in canonical Wnt signaling and a decrease in sclerostin protein levels are involved in strontium ranelate-induced osteogenic effects in human osteoblasts. J Biol Chem 286:23771-23779
-
(2011)
J Biol Chem
, vol.286
, pp. 23771-23779
-
-
Rybchyn, M.S.1
Slater, M.2
Conigrave, A.D.3
Mason, R.S.4
-
76
-
-
21344450560
-
SOST/sclerostin, an osteocyte-derived negative regulator of bone formation
-
15869900 10.1016/j.cytogfr.2005.02.005
-
van Bezooijen RL, Dijke P, Papapoulos SE, Lowik CW (2005) SOST/sclerostin, an osteocyte-derived negative regulator of bone formation. Cytokine Growth Factor Rev 16:319-327
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 319-327
-
-
Van Bezooijen, R.L.1
Dijke, P.2
Papapoulos, S.E.3
Lowik, C.W.4
-
77
-
-
27744461726
-
Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation
-
16123173 1:CAS:528:DC%2BD2MXht1emsbrP
-
Poole KE, van Bezooijen RL, Loveridge N, Hamersma H, Papapoulos SE, Löwik CW, Reeve J (2005) Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation. FASEB J 19:1842-1844
-
(2005)
FASEB J
, vol.19
, pp. 1842-1844
-
-
Poole, K.E.1
Van Bezooijen, R.L.2
Loveridge, N.3
Hamersma, H.4
Papapoulos, S.E.5
Löwik, C.W.6
Reeve, J.7
-
79
-
-
65549152230
-
Sclerostin antibody treatment increases bone formation, bone mass and bone strength in a rat model of postmenopausal osteoporosis
-
19049336 10.1359/jbmr.081206 1:CAS:528:DC%2BD1MXksF2lu7c%3D
-
Li X, Ominsky MS, Warmington KS et al (2009) Sclerostin antibody treatment increases bone formation, bone mass and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res 24:578-588
-
(2009)
J Bone Miner Res
, vol.24
, pp. 578-588
-
-
Li, X.1
Ominsky, M.S.2
Warmington, K.S.3
-
80
-
-
77956815310
-
Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats
-
20641040 10.1002/jbmr.182
-
Li X, Warmington KS, Niu QT, Asuncion FJ, Barrero M, Grisanti M, Dwyer D, Stouch B, Thway TM, Stolina M, Ominsky MS, Kostenuik PJ, Simonet WS, Paszty C, Ke HZ (2010) Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats. J Bone Miner Res 25:2647-2656
-
(2010)
J Bone Miner Res
, vol.25
, pp. 2647-2656
-
-
Li, X.1
Warmington, K.S.2
Niu, Q.T.3
Asuncion, F.J.4
Barrero, M.5
Grisanti, M.6
Dwyer, D.7
Stouch, B.8
Thway, T.M.9
Stolina, M.10
Ominsky, M.S.11
Kostenuik, P.J.12
Simonet, W.S.13
Paszty, C.14
Ke, H.Z.15
-
81
-
-
77955844659
-
Treatment with a sclerostin antibody increases cancellous bone formation and bone mass regardless of marrow composition in adult female rats
-
20561907 10.1016/j.bone.2010.05.032 1:CAS:528:DC%2BC3cXhtVGmur%2FI
-
Tian X, Setterberg RB, Li X, Paszty C, Ke HZ, Jee WS (2010) Treatment with a sclerostin antibody increases cancellous bone formation and bone mass regardless of marrow composition in adult female rats. Bone 47:529-533
-
(2010)
Bone
, vol.47
, pp. 529-533
-
-
Tian, X.1
Setterberg, R.B.2
Li, X.3
Paszty, C.4
Ke, H.Z.5
Jee, W.S.6
-
82
-
-
77956822573
-
Sclerostin antibody treatment enhances metaphyseal bone healing in rats
-
20499342 10.1002/jbmr.135 1:CAS:528:DC%2BC3cXhsVOjtbzJ
-
Agholme F, Li X, Isaksson H, Ke HZ, Aspenberg P (2010) Sclerostin antibody treatment enhances metaphyseal bone healing in rats. J Bone Miner Res 25:2412-2418
-
(2010)
J Bone Miner Res
, vol.25
, pp. 2412-2418
-
-
Agholme, F.1
Li, X.2
Isaksson, H.3
Ke, H.Z.4
Aspenberg, P.5
-
83
-
-
79955635177
-
Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones
-
10.1002/jbmr.307 1:CAS:528:DC%2BC3MXmslWlsbg%3D
-
Ominsky MS, Li C, Li X, Tan HL, Lee E, Barrero M, Asuncion FJ, Dwyer D, Han CY, Vlasseros F, Samadfam R, Jolette J, Smith SY, Stolina M, Lacey DL, Simonet WS, Paszty C, Li G, Ke HZ (2011) Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones. J Bone Mineral Res 26:1012-1021
-
(2011)
J Bone Mineral Res
, vol.26
, pp. 1012-1021
-
-
Ominsky, M.S.1
Li, C.2
Li, X.3
Tan, H.L.4
Lee, E.5
Barrero, M.6
Asuncion, F.J.7
Dwyer, D.8
Han, C.Y.9
Vlasseros, F.10
Samadfam, R.11
Jolette, J.12
Smith, S.Y.13
Stolina, M.14
Lacey, D.L.15
Simonet, W.S.16
Paszty, C.17
Li, G.18
Ke, H.Z.19
-
84
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
18269310 10.1359/jbmr.080216
-
Li X, Ominsky MS, Niu QT, Sun N, Daugherty B, D'Agostin D, Kurahara C, Gao Y, Cao J, Gong J, Asuncion F, Barrero M, Warmington K, Dwyer D, Stolina M, Morony S, Sarosi I, Kostenuik PJ, Lacey DL, Simonet WS, Ke HZ, Paszty C (2008) Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res 23:860-869
-
(2008)
J Bone Miner Res
, vol.23
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.T.3
Sun, N.4
Daugherty, B.5
D'Agostin, D.6
Kurahara, C.7
Gao, Y.8
Cao, J.9
Gong, J.10
Asuncion, F.11
Barrero, M.12
Warmington, K.13
Dwyer, D.14
Stolina, M.15
Morony, S.16
Sarosi, I.17
Kostenuik, P.J.18
Lacey, D.L.19
Simonet, W.S.20
Ke, H.Z.21
Paszty, C.22
more..
-
85
-
-
84865509876
-
Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats
-
22457198 10.1002/jor.22109 1:CAS:528:DC%2BC38Xht1eksbfE
-
McDonald MM, Morse A, Mikulec K, Peacock L, Yu N, Baldock PA, Birke O, Liu M, Ke HZ, Little DG (2012) Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats. J Orthop Res 30:1541-1548
-
(2012)
J Orthop Res
, vol.30
, pp. 1541-1548
-
-
McDonald, M.M.1
Morse, A.2
Mikulec, K.3
Peacock, L.4
Yu, N.5
Baldock, P.A.6
Birke, O.7
Liu, M.8
Ke, H.Z.9
Little, D.G.10
-
86
-
-
77953481395
-
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
-
20200929 10.1002/jbmr.14 1:CAS:528:DC%2BC3cXnt1Kisrg%3D
-
Ominsky MS, Vlasseros F, Jolette J, Smith SY, Stouch B, Doellgast G, Gong J, Gao Y, Cao J, Graham K, Tipton B, Cai J, Deshpande R, Zhou L, Hale MD, Lightwood DJ, Henry AJ, Popplewell AG, Moore AR, Robinson MK, Lacey DL, Simonet WS, Paszty C (2010) Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength. J Bone Miner Res 25:948-959
-
(2010)
J Bone Miner Res
, vol.25
, pp. 948-959
-
-
Ominsky, M.S.1
Vlasseros, F.2
Jolette, J.3
Smith, S.Y.4
Stouch, B.5
Doellgast, G.6
Gong, J.7
Gao, Y.8
Cao, J.9
Graham, K.10
Tipton, B.11
Cai, J.12
Deshpande, R.13
Zhou, L.14
Hale, M.D.15
Lightwood, D.J.16
Henry, A.J.17
Popplewell, A.G.18
Moore, A.R.19
Robinson, M.K.20
Lacey, D.L.21
Simonet, W.S.22
Paszty, C.23
more..
-
87
-
-
78650958526
-
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
-
20593411 10.1002/jbmr.173 1:CAS:528:DC%2BC3MXhtlCgsr8%3D
-
Padhi D, Jang G, Stouch B, Fang L, Posvar E (2011) Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 26:19-26
-
(2011)
J Bone Miner Res
, vol.26
, pp. 19-26
-
-
Padhi, D.1
Jang, G.2
Stouch, B.3
Fang, L.4
Posvar, E.5
-
88
-
-
19044364417
-
Early changes in biochemical markers of bone formation predict BMD response to teriparatide in postmenopausal women with osteoporosis
-
15883636 10.1359/JBMR.050105 1:CAS:528:DC%2BD2MXlsFehtr0%3D
-
Chen P, Satterwhite JH, Licata AA, Lewiecki EM, Sipos AA, Misurski DM, Wagman RB (2005) Early changes in biochemical markers of bone formation predict BMD response to teriparatide in postmenopausal women with osteoporosis. J Bone Miner Res 20:962-970
-
(2005)
J Bone Miner Res
, vol.20
, pp. 962-970
-
-
Chen, P.1
Satterwhite, J.H.2
Licata, A.A.3
Lewiecki, E.M.4
Sipos, A.A.5
Misurski, D.M.6
Wagman, R.B.7
-
89
-
-
0037406825
-
The anabolic effects of parathyroid hormone therapy
-
12916294 10.1016/S0749-0690(02)00074-5
-
Rubin MR, Bilezikian JP (2003) The anabolic effects of parathyroid hormone therapy. Clin Geriatr Med 19:415-432
-
(2003)
Clin Geriatr Med
, vol.19
, pp. 415-432
-
-
Rubin, M.R.1
Bilezikian, J.P.2
-
90
-
-
84872187821
-
Inhibition of sclerostin with AMG 785 in postmenopausal women with low bone mineral density: Phase 2 trial results
-
McClung MR, Grauer A, Boonen S, Brown JP, Diez-Perez A, Langdahl B, Reginster JY, Zanchetta JR, Katz L, Maddox J, Yang YC, Libanati C, Bone HG (2012) Inhibition of sclerostin with AMG 785 in postmenopausal women with low bone mineral density: phase 2 trial results. J Bone Mineral Res 27:s8
-
(2012)
J Bone Mineral Res
, vol.27
, pp. 8
-
-
McClung, M.R.1
Grauer, A.2
Boonen, S.3
Brown, J.P.4
Diez-Perez, A.5
Langdahl, B.6
Reginster, J.Y.7
Zanchetta, J.R.8
Katz, L.9
Maddox, J.10
Yang, Y.C.11
Libanati, C.12
Bone, H.G.13
-
91
-
-
33846025409
-
Knocking down dickkopf-1 alleviates estrogen deficiency induction of bone loss. A histomorphological study in ovariectomized rats
-
17055793 10.1016/j.bone.2006.09.004 1:CAS:528:DC%2BD2sXmtVGjtQ%3D%3D
-
Wang FS, Ko JY, Lin CL, Wu HL, Ke HJ, Tai PJ (2007) Knocking down dickkopf-1 alleviates estrogen deficiency induction of bone loss. A histomorphological study in ovariectomized rats. Bone 40:485-492
-
(2007)
Bone
, vol.40
, pp. 485-492
-
-
Wang, F.S.1
Ko, J.Y.2
Lin, C.L.3
Wu, H.L.4
Ke, H.J.5
Tai, P.J.6
-
92
-
-
41549138806
-
Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss
-
18174290 10.1210/en.2007-0910 1:CAS:528:DC%2BD1cXktVeqs7k%3D
-
Wang FS, Ko JY, Yeh DW, Ke HC, Wu HL (2008) Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss. Endocrinology 149:1793-1801
-
(2008)
Endocrinology
, vol.149
, pp. 1793-1801
-
-
Wang, F.S.1
Ko, J.Y.2
Yeh, D.W.3
Ke, H.C.4
Wu, H.L.5
-
93
-
-
57649158485
-
Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment
-
19067746 10.1111/j.1600-0609.2008.01164.x 1:CAS:528:DC%2BD1MXhvVKlsL4%3D
-
Heider U, Kaiser M, Mieth M, Lamottke B, Rademacher J, Jakob C, Braendle E, Stover D, Sezer O (2009) Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment. Eur J Haematol 82:31-38
-
(2009)
Eur J Haematol
, vol.82
, pp. 31-38
-
-
Heider, U.1
Kaiser, M.2
Mieth, M.3
Lamottke, B.4
Rademacher, J.5
Jakob, C.6
Braendle, E.7
Stover, D.8
Sezer, O.9
-
94
-
-
33847397091
-
Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo
-
17068150 10.1182/blood-2006-09-047712 1:CAS:528:DC%2BD2sXjtFequrY%3D
-
Yaccoby S, Ling W, Zhan F, Walker R, Barlogie B, Shaughnessy JD Jr (2007) Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo. Blood 109:2106-2111
-
(2007)
Blood
, vol.109
, pp. 2106-2111
-
-
Yaccoby, S.1
Ling, W.2
Zhan, F.3
Walker, R.4
Barlogie, B.5
Shaughnessy, Jr.J.D.6
-
95
-
-
67650431302
-
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
-
19417213 10.1182/blood-2008-11-191577 1:CAS:528:DC%2BD1MXovVKlsrs%3D
-
Fulciniti M, Tassone P, Hideshima T, Vallet S, Nanjappa P, Ettenberg SA, Shen Z, Patel N, Tai YT, Chauhan D, Mitsiades C, Prabhala R, Raje N, Anderson KC, Stover DR, Munshi NC (2009) Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma. Blood 114:371-379
-
(2009)
Blood
, vol.114
, pp. 371-379
-
-
Fulciniti, M.1
Tassone, P.2
Hideshima, T.3
Vallet, S.4
Nanjappa, P.5
Ettenberg, S.A.6
Shen, Z.7
Patel, N.8
Tai, Y.T.9
Chauhan, D.10
Mitsiades, C.11
Prabhala, R.12
Raje, N.13
Anderson, K.C.14
Stover, D.R.15
Munshi, N.C.16
-
96
-
-
78649723963
-
Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression
-
20858621 10.1136/ard.2010.132852 1:CAS:528:DC%2BC3cXhs1emsb%2FI
-
Heiland GR, Zwerina K, Baum W, Kireva T, Distler JH, Grisanti M, Asuncion F, Li X, Ominsky M, Richards W, Schett G, Zwerina J (2010) Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression. Ann Rheum Dis 69:2152-2159
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 2152-2159
-
-
Heiland, G.R.1
Zwerina, K.2
Baum, W.3
Kireva, T.4
Distler, J.H.5
Grisanti, M.6
Asuncion, F.7
Li, X.8
Ominsky, M.9
Richards, W.10
Schett, G.11
Zwerina, J.12
-
97
-
-
65249167488
-
Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomsgenesis in mice
-
19307728 10.1172/JCI37175 1:CAS:528:DC%2BD1MXktlSntrY%3D
-
Kansara M, Tsang M, Kodjabachian L, Sims NA, Trivett MK, Ehrich M, Dobrovic A, Slavin J, Choong PF, Simmons PJ, Dawid IB, Thomas DM (2009) Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomsgenesis in mice. J Clin Invest 119:837-851
-
(2009)
J Clin Invest
, vol.119
, pp. 837-851
-
-
Kansara, M.1
Tsang, M.2
Kodjabachian, L.3
Sims, N.A.4
Trivett, M.K.5
Ehrich, M.6
Dobrovic, A.7
Slavin, J.8
Choong, P.F.9
Simmons, P.J.10
Dawid, I.B.11
Thomas, D.M.12
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