Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: Implication to age-associated bone diseases and defects

Mechanisms of Ageing and Development

Volumn 133, Issue 5, 2012, Pages 215-225

  Kim, MiJung ^a,b,c,d   Kim, ChanWha ^d   Choi, Yu Suk ^c   Kim, MinHwan ^c   Park, ChanJeoung ^b   Suh, Yousin ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b University of Ulsan College of Medicine   (South Korea)

^c Asan Institute for Life Sciences   (South Korea)

^d Korea University   (South Korea)

Author keywords

Adipogenesis; Aging; Cell therapy; Mesenchymal stem cells (MSC); Osteogenesis

Indexed keywords

MICRORNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; TELOMERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR RUNX2;

ADIPOGENESIS; AGE ASSOCIATED BONE DISEASE; AGING; ARTICLE; BONE DEVELOPMENT; BONE DISEASE; BONE MARROW; CELL AGING; CELL FATE; CELL LINEAGE; CELL PROLIFERATION; CELL STRUCTURE; ENERGY METABOLISM; ENZYME ACTIVITY; HEMATOPOIETIC STEM CELL; HUMAN; MESENCHYMAL STEM CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA PROCESSING; SIGNAL TRANSDUCTION; STEM CELL NICHE; STEM CELL TRANSPLANTATION; TELOMERE SHORTENING;

ADIPOGENESIS; AGING; ANIMALS; BONE DISEASES; CELL PROLIFERATION; FEMALE; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; MESENCHYMAL STEM CELLS; MICE; MICRORNAS; OSTEOGENESIS; OXIDATIVE STRESS; RATS; TELOMERASE; TELOMERE; TRANSCRIPTION FACTORS;

EID: 84861233517     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2012.03.014     Document Type: Article

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