-
1
-
-
84975755192
-
Mitochondrial ROS signaling in organismal homeostasis
-
[CrossRef] [PubMed]
-
Shadel, G.S.; Horvath, T.L. Mitochondrial ROS signaling in organismal homeostasis. Cell 2015, 163, 560-569. [CrossRef] [PubMed]
-
(2015)
Cell
, vol.163
, pp. 560-569
-
-
Shadel, G.S.1
Horvath, T.L.2
-
2
-
-
79957597757
-
Mitochondria in innate immune responses
-
[CrossRef] [PubMed]
-
West, A.P.; Shadel, G.S.; Ghosh, S. Mitochondria in innate immune responses. Nat. Rev. Immunol. 2011, 11, 389-402. [CrossRef] [PubMed]
-
(2011)
Nat. Rev. Immunol
, vol.11
, pp. 389-402
-
-
West, A.P.1
Shadel, G.S.2
Ghosh, S.3
-
3
-
-
85006768050
-
The Metabolism of tumors in the body
-
[CrossRef] [PubMed]
-
Warburg, O.; Wind, F.; Negelein, E. The Metabolism of tumors in the body. J. Gen. Physiol. 1927, 8, 519-530. [CrossRef] [PubMed]
-
(1927)
J. Gen. Physiol
, vol.8
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
5
-
-
0035150912
-
The molecular biology of cancer
-
[CrossRef]
-
Bertram, J.S. The molecular biology of cancer. Mol. Aspects Med. 2000, 21, 167-223. [CrossRef]
-
(2000)
Mol. Aspects Med
, vol.21
, pp. 167-223
-
-
Bertram, J.S.1
-
6
-
-
69549088424
-
SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma
-
[CrossRef] [PubMed]
-
Hao, H.X.; Khalimonchuk, O.; Schraders, M.; Dephoure, N.; Bayley, J.P.; Kunst, H.; Devilee, P.; Cremers, C.W.; Schiffman, J.D.; Bentz, B.G.; et al. SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science 2009, 325, 1139-1142. [CrossRef] [PubMed]
-
(2009)
Science
, vol.325
, pp. 1139-1142
-
-
Hao, H.X.1
Khalimonchuk, O.2
Schraders, M.3
Dephoure, N.4
Bayley, J.P.5
Kunst, H.6
Devilee, P.7
Cremers, C.W.8
Schiffman, J.D.9
Bentz, B.G.10
-
7
-
-
77953608893
-
Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Barking up the right tree?
-
[CrossRef] [PubMed]
-
Bayley, J.P.; Devilee, P. Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Barking up the right tree? Curr. Opin. Genet. Dev. 2010, 20, 324-329. [CrossRef] [PubMed]
-
(2010)
Curr. Opin. Genet. Dev
, vol.20
, pp. 324-329
-
-
Bayley, J.P.1
Devilee, P.2
-
8
-
-
84880404541
-
Mitochondrial alterations during carcinogenesis: A review of metabolic transformation and targets for anticancer treatments
-
[PubMed]
-
Wang, X.; Peralta, S.; Moraes, C.T. Mitochondrial alterations during carcinogenesis: A review of metabolic transformation and targets for anticancer treatments. Adv. Cancer Res. 2013, 119, 127-160. [PubMed]
-
(2013)
Adv. Cancer Res
, vol.119
, pp. 127-160
-
-
Wang, X.1
Peralta, S.2
Moraes, C.T.3
-
9
-
-
85006216389
-
Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect
-
[PubMed]
-
Zhang, S.; Yang, C.; Yang, Z.; Zhang, D.; Ma, X.; Mills, G.; Liu, Z. Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect. Am. J. Cancer Res. 2015, 5, 928-944. [PubMed]
-
(2015)
Am. J. Cancer Res
, vol.5
, pp. 928-944
-
-
Zhang, S.1
Yang, C.2
Yang, Z.3
Zhang, D.4
Ma, X.5
Mills, G.6
Liu, Z.7
-
10
-
-
84895809519
-
Cancer as a metabolic disease: Implications for novel therapeutics
-
[CrossRef] [PubMed]
-
Seyfried, T.N.; Flores, R.E.; Poff, A.M.; D'Agostino, D.P. Cancer as a metabolic disease: Implications for novel therapeutics. Carcinogenesis 2014, 35, 515-527. [CrossRef] [PubMed]
-
(2014)
Carcinogenesis
, vol.35
, pp. 515-527
-
-
Seyfried, T.N.1
Flores, R.E.2
Poff, A.M.3
D'agostino, D.P.4
-
11
-
-
84890406729
-
Is cancer a metabolic disease
-
[CrossRef] [PubMed]
-
Coller, H.A. Is cancer a metabolic disease? Am. J. Pathol. 2014, 184, 4-17. [CrossRef] [PubMed]
-
(2014)
Am. J. Pathol
, vol.184
, pp. 4-17
-
-
Coller, H.A.1
-
12
-
-
84959256773
-
Mitochondria in cancer energy metabolism: Culprits or bystanders?
-
[CrossRef] [PubMed]
-
Kim, A. Mitochondria in cancer energy metabolism: Culprits or bystanders? Toxicol. Res. 2015, 31, 323-330. [CrossRef] [PubMed]
-
(2015)
Toxicol. Res
, vol.31
, pp. 323-330
-
-
Kim, A.1
-
13
-
-
80052266526
-
Cross talk between mitochondria and NADPH oxidases. Free Radic
-
[CrossRef] [PubMed]
-
Dikalov, S. Cross talk between mitochondria and NADPH oxidases. Free Radic. Biol. Med. 2011, 51, 1289-1301. [CrossRef] [PubMed]
-
(2011)
Biol. Med
, vol.51
, pp. 1289-1301
-
-
Dikalov, S.1
-
14
-
-
84947869935
-
Reactive oxygen species regulate Smac mimetic/TNFalpha-induced necroptotic signaling and cell death
-
[CrossRef] [PubMed]
-
Schenk, B.; Fulda, S. Reactive oxygen species regulate Smac mimetic/TNFalpha-induced necroptotic signaling and cell death. Oncogene 2015, 34, 5796-5806. [CrossRef] [PubMed]
-
(2015)
Oncogene
, vol.34
, pp. 5796-5806
-
-
Schenk, B.1
Fulda, S.2
-
15
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
[CrossRef]
-
Liu, X.; Kim, C.N.; Yang, J.; Jemmerson, R.; Wang, X. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 1996, 86, 147-157. [CrossRef]
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
16
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
[CrossRef] [PubMed]
-
Zamzami, N.; Susin, S.A.; Marchetti, P.; Hirsch, T.; Gómez-Monterrey, I.; Castedo, M.; Kroemer, G. Mitochondrial control of nuclear apoptosis. J. Exp. Med. 1996, 183, 1533-1544.[CrossRef] [PubMed]
-
(1996)
J. Exp. Med
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
Susin, S.A.2
Marchetti, P.3
Hirsch, T.4
Gómez-Monterrey, I.5
Castedo, M.6
Kroemer, G.7
-
17
-
-
84869024586
-
New components of the necroptotic pathway
-
[CrossRef] [PubMed]
-
Zhou, Z.; Han, V.; Han, J. New components of the necroptotic pathway. Protein Cell 2012, 3, 811-817. [CrossRef] [PubMed]
-
(2012)
Protein Cell
, vol.3
, pp. 811-817
-
-
Zhou, Z.1
Han, V.2
Han, J.3
-
18
-
-
33751522909
-
The redox regulation of thiol dependent signaling pathways in cancer
-
[CrossRef] [PubMed]
-
Giles, G.I. The redox regulation of thiol dependent signaling pathways in cancer. Curr. Pharm. Des. 2006, 12, 4427-4443. [CrossRef] [PubMed]
-
(2006)
Curr. Pharm. Des
, vol.12
, pp. 4427-4443
-
-
Giles, G.I.1
-
19
-
-
32444433202
-
Free radicals, metals and antioxidants in oxidative stress-induced cancer
-
[CrossRef] [PubMed]
-
Valko, M.; Rhodes, C.J.; Moncol, J.; Izakovic, M.; Mazur, M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 2006, 160, 1-40. [CrossRef] [PubMed]
-
(2006)
Chem. Biol. Interact
, vol.160
, pp. 1-40
-
-
Valko, M.1
Rhodes, C.J.2
Moncol, J.3
Izakovic, M.4
Mazur, M.5
-
20
-
-
78049370987
-
Oxidative stress, inflammation, and cancer: How are they linked?
-
[CrossRef] [PubMed]
-
Reuter, S.; Gupta, S.C.; Chaturvedi, M.M.; Aggarwal, B.B. Oxidative stress, inflammation, and cancer: How are they linked? Free Radic. Biol. Med. 2010, 49, 1603-1616. [CrossRef] [PubMed]
-
(2010)
Free Radic. Biol. Med
, vol.49
, pp. 1603-1616
-
-
Reuter, S.1
Gupta, S.C.2
Chaturvedi, M.M.3
Aggarwal, B.B.4
-
21
-
-
33846117134
-
The signaling mechanism of ROS in tumor progression
-
[CrossRef] [PubMed]
-
Wu, W.S. The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev. 2006, 25, 695-705. [CrossRef] [PubMed]
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 695-705
-
-
Wu, W.S.1
-
22
-
-
3242752786
-
Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells
-
[CrossRef] [PubMed]
-
Boonstra, J.; Post, J.A. Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells. Gene 2004, 337, 1-13. [CrossRef] [PubMed]
-
(2004)
Gene
, vol.337
, pp. 1-13
-
-
Boonstra, J.1
Post, J.A.2
-
23
-
-
84878006508
-
Mitochondrial superoxide mediates mitochondrial and endoplasmic reticulum dysfunctions in TRAIL-induced apoptosis in Jurkat cells
-
[CrossRef] [PubMed]
-
Inoue, T.; Suzuki-Karasaki, Y. Mitochondrial superoxide mediates mitochondrial and endoplasmic reticulum dysfunctions in TRAIL-induced apoptosis in Jurkat cells. Free Radic. Biol. Med. 2013, 61, 273-284. [CrossRef] [PubMed]
-
(2013)
Free Radic. Biol. Med
, vol.61
, pp. 273-284
-
-
Inoue, T.1
Suzuki-Karasaki, Y.2
-
24
-
-
0033192573
-
Oxidant stress regulation of IL-8 and ICAM-1 gene expression: Differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review)
-
[CrossRef] [PubMed]
-
Roebuck, K.A. Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review). Int. J. Mol. Med. 1999, 4, 223-230. [CrossRef] [PubMed]
-
(1999)
Int. J. Mol. Med
, vol.4
, pp. 223-230
-
-
Roebuck, K.A.1
-
25
-
-
0030764713
-
Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine beta and gamma proteins
-
[CrossRef]
-
Owen, J.D.; Strieter, R.; Burdick, M.; Haghnegahdar, H.; Nanney, L.; Shattuck-Brandt, R.; Richmond, A. Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine beta and gamma proteins. Int. J. Cancer 1997, 73, 94-103. [CrossRef]
-
(1997)
Int. J. Cancer
, vol.73
, pp. 94-103
-
-
Owen, J.D.1
Strieter, R.2
Burdick, M.3
Haghnegahdar, H.4
Nanney, L.5
Shattuck-Brandt, R.6
Richmond, A.7
-
26
-
-
34547608157
-
MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells
-
[CrossRef] [PubMed]
-
Sodek, K.L.; Ringuette, M.J.; Brown, T.J. MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells. Br. J. Cancer 2007, 97, 358-367. [CrossRef] [PubMed]
-
(2007)
Br. J. Cancer
, vol.97
, pp. 358-367
-
-
Sodek, K.L.1
Ringuette, M.J.2
Brown, T.J.3
-
27
-
-
0032482939
-
Antiangiogenic gene therapy
-
[CrossRef] [PubMed]
-
Folkman, J. Antiangiogenic gene therapy. Proc. Natl. Acad. Sci. USA 1998, 95, 9064-9066. [CrossRef] [PubMed]
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9064-9066
-
-
Folkman, J.1
-
28
-
-
0011160261
-
Long-term culture of capillary endothelial cells
-
[CrossRef] [PubMed]
-
Folkman, J.; Haudenschild, C.C.; Zetter, B.R. Long-term culture of capillary endothelial cells. Proc. Natl. Acad. Sci. USA 1979, 76, 5217-5721. [CrossRef] [PubMed]
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 5217-5721
-
-
Folkman, J.1
Haudenschild, C.C.2
Zetter, B.R.3
-
29
-
-
0026639806
-
Angiogenesis
-
[PubMed]
-
Folkman, J.; Shing, Y. Angiogenesis. J. Biol. Chem. 1992, 267, 10931-10934. [PubMed]
-
(1992)
J. Biol. Chem
, vol.267
, pp. 10931-10934
-
-
Folkman, J.1
Shing, Y.2
-
30
-
-
77951953059
-
Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: Implications for cardiac aging
-
[CrossRef] [PubMed]
-
Gallogly, M.M.; Shelton, M.D.; Qanungo, S.; Pai, H.V.; Starke, D.W.; Hoppel, C.L.; Lesnefsky, E.J.; Mieyal, J.J. Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: Implications for cardiac aging. Antioxid. Redox Signal. 2010, 12, 1339-1353. [CrossRef] [PubMed]
-
(2010)
Antioxid. Redox Signal
, vol.12
, pp. 1339-1353
-
-
Gallogly, M.M.1
Shelton, M.D.2
Qanungo, S.3
Pai, H.V.4
Starke, D.W.5
Hoppel, C.L.6
Lesnefsky, E.J.7
Mieyal, J.J.8
-
31
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
[CrossRef] [PubMed]
-
Papandreou, I.; Cairns, R.A.; Fontana, L.; Lim, A.L.; Denko, N.C. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006, 3, 187-197. [CrossRef] [PubMed]
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
32
-
-
84941207700
-
Oxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing loss
-
[CrossRef] [PubMed]
-
Kwon, D.N.; Park, W.J.; Choi, Y.J.; Gurunathan, S.; Kim, J.H. Oxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing loss. Aging (Albany NY) 2015, 7, 579-594. [CrossRef] [PubMed]
-
(2015)
Aging (Albany NY)
, vol.7
, pp. 579-594
-
-
Kwon, D.N.1
Park, W.J.2
Choi, Y.J.3
Gurunathan, S.4
Kim, J.H.5
-
33
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
[CrossRef] [PubMed]
-
Li, Y.; Huang, T.T.; Carlson, E.J.; Melov, S.; Ursell, P.C.; Olson, J.L.; Noble, L.J.; Yoshimura, M.P.; Berger, C.; Chan, P.H.; et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat. Genet. 1995, 11, 376-381. [CrossRef] [PubMed]
-
(1995)
Nat. Genet
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melov, S.4
Ursell, P.C.5
Olson, J.L.6
Noble, L.J.7
Yoshimura, M.P.8
Berger, C.9
Chan, P.H.10
-
34
-
-
0035839505
-
Identification and characterization of a new mammalian glutaredoxin (Thioltransferase), Grx2
-
[CrossRef] [PubMed]
-
Gladyshev, V.N.; Liu, A.; Novoselov, S.V.; Krysan, K.; Sun, Q.A.; Kryukov, V.M.; Kryukov, G.V.; Lou, M.F. Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2. J. Biol. Chem. 2001, 276, 30374-30380. [CrossRef] [PubMed]
-
(2001)
J. Biol. Chem
, vol.276
, pp. 30374-30380
-
-
Gladyshev, V.N.1
Liu, A.2
Novoselov, S.V.3
Krysan, K.4
Sun, Q.A.5
Kryukov, V.M.6
Kryukov, G.V.7
Lou, M.F.8
-
35
-
-
0032813701
-
Murine phospholipid hydroperoxide glutathione peroxidase: CDNA sequence, tissue expression, and mapping
-
[CrossRef] [PubMed]
-
Knopp, E.A.; Arndt, T.L.; Eng, K.L.; Caldwell, M.; LeBoeuf, R.C.; Deeb, S.S.; O'Brien, K.D. Murine phospholipid hydroperoxide glutathione peroxidase: cDNA sequence, tissue expression, and mapping. Mamm. Genome 1999, 10, 601-605. [CrossRef] [PubMed]
-
(1999)
Mamm. Genome
, vol.10
, pp. 601-605
-
-
Knopp, E.A.1
Arndt, T.L.2
Eng, K.L.3
Caldwell, M.4
Leboeuf, R.C.5
Deeb, S.S.6
O'brien, K.D.7
-
36
-
-
0034511476
-
The mitochondrial thioredoxin system
-
[CrossRef] [PubMed]
-
Miranda-Vizuete, A.; Damdimopoulos, A.E.; Spyrou, G. The mitochondrial thioredoxin system. Antioxid. Redox Signal. 2000, 2, 801-810. [CrossRef] [PubMed]
-
(2000)
Antioxid. Redox Signal
, vol.2
, pp. 801-810
-
-
Miranda-Vizuete, A.1
Damdimopoulos, A.E.2
Spyrou, G.3
-
37
-
-
84946560207
-
Redox mechanisms of cardiomyocyte mitochondrial protection
-
[CrossRef] [PubMed]
-
Bartz, R.R.; Suliman, H.B.; Piantadosi, C.A. Redox mechanisms of cardiomyocyte mitochondrial protection. Front. Physiol. 2015. [CrossRef] [PubMed]
-
(2015)
Front. Physiol
-
-
Bartz, R.R.1
Suliman, H.B.2
Piantadosi, C.A.3
-
38
-
-
0014691242
-
Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
-
[CrossRef] [PubMed]
-
McCord, J.M.; Fridovich, I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem. 1969, 244, 6049-6055. [CrossRef] [PubMed]
-
(1969)
J. Biol. Chem
, vol.244
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
39
-
-
3042736846
-
Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology
-
[CrossRef] [PubMed]
-
Spitz, D.R.; Azzam, E.I.; Li, J.J.; Gius, D. Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology. Cancer Metastasis Rev. 2004, 23, 311-322. [CrossRef] [PubMed]
-
(2004)
Cancer Metastasis Rev
, vol.23
, pp. 311-322
-
-
Spitz, D.R.1
Azzam, E.I.2
Li, J.J.3
Gius, D.4
-
40
-
-
84861628788
-
Manganese superoxide dismutase regulation and cancer. Free Radic
-
[CrossRef] [PubMed]
-
Dhar, S.K.; St. Clair, D.K. Manganese superoxide dismutase regulation and cancer. Free Radic. Biol. Med. 2012, 52, 2209-2222. [CrossRef] [PubMed]
-
(2012)
Biol. Med
, vol.52
, pp. 2209-2222
-
-
Dhar, S.K.1
Clair, S.2
-
41
-
-
0026033905
-
Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells
-
[PubMed]
-
St. Clair D.K.; Holland, J.C. Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells. Cancer Res. 1991, 51, 939-943. [PubMed]
-
(1991)
Cancer Res
, vol.51
, pp. 939-943
-
-
Clair, S.T.1
Holland, J.C.2
-
42
-
-
0034699513
-
Superoxide dismutase as a target for the selective killing of cancer cells
-
[CrossRef] [PubMed]
-
Huang, P.; Feng, L.; Oldham, E.A.; Keating, M.J.; Plunkett, W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 2000, 407, 390-395. [CrossRef] [PubMed]
-
(2000)
Nature
, vol.407
, pp. 390-395
-
-
Huang, P.1
Feng, L.2
Oldham, E.A.3
Keating, M.J.4
Plunkett, W.5
-
43
-
-
0034938799
-
Anticancer therapy by overexpression of superoxide dismutase
-
[CrossRef] [PubMed]
-
Oberley, L.W. Anticancer therapy by overexpression of superoxide dismutase. Antioxid. Redox Signal. 2001, 3, 461-472. [CrossRef] [PubMed]
-
(2001)
Antioxid. Redox Signal
, vol.3
, pp. 461-472
-
-
Oberley, L.W.1
-
44
-
-
0029838063
-
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
-
[CrossRef] [PubMed]
-
Lebovitz, R.M.; Zhang, H.; Vogel, H.; Cartwright, J., Jr.; Dionne, L.; Lu, N.; Huang, S.; Matzuk, M.M. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc. Natl. Acad. Sci. USA 1996, 93, 9782-9787. [CrossRef] [PubMed]
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
Cartwright, J.4
Dionne, L.5
Lu, N.6
Huang, S.7
Matzuk, M.M.8
-
45
-
-
0029801944
-
Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells
-
[PubMed]
-
Zhong, W.; Oberley, L.W.; Oberley, T.D.; Yan, T.; Domann, F.E.; St Clair, D.K. Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells. Cell Growth Differ. 1996, 7, 1175-1186. [PubMed]
-
(1996)
Cell Growth Differ
, vol.7
, pp. 1175-1186
-
-
Zhong, W.1
Oberley, L.W.2
Oberley, T.D.3
Yan, T.4
Domann, F.E.5
St Clair, D.K.6
-
46
-
-
0029032567
-
Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase
-
[PubMed]
-
Li, J.J.; Oberley, L.W.; St Clair, D.K.; Ridnour, L.A.; Oberley, T.D. Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase. Oncogene 1995, 10, 1989-2000. [PubMed]
-
(1995)
Oncogene
, vol.10
, pp. 1989-2000
-
-
Li, J.J.1
Oberley, L.W.2
St Clair, D.K.3
Ridnour, L.A.4
Oberley, T.D.5
-
47
-
-
13944264308
-
A mechanism-based antioxidant approach for the reduction of skin carcinogenesis
-
[CrossRef] [PubMed]
-
Zhao, Y.; Chaiswing, L.; Oberley, T.D.; Batinic-Haberle, I.; St Clair, W.; Epstein, C.J.; St Clair, D. A mechanism-based antioxidant approach for the reduction of skin carcinogenesis. Cancer Res. 2005, 65, 1401-1405. [CrossRef] [PubMed]
-
(2005)
Cancer Res
, vol.65
, pp. 1401-1405
-
-
Zhao, Y.1
Chaiswing, L.2
Oberley, T.D.3
Batinic-Haberle, I.4
St Clair, W.5
Epstein, C.J.6
St Clair, D.7
-
48
-
-
3743050370
-
Inhibition of AP-1 and NF-kappaB by manganese-containing superoxide dismutase in human breast cancer cells
-
[PubMed]
-
Li, J.J.; Oberley, L.W.; Fan, M.; Colburn, N.H. Inhibition of AP-1 and NF-kappaB by manganese-containing superoxide dismutase in human breast cancer cells. FASEB J. 1998, 12, 1713-1723. [PubMed]
-
(1998)
FASEB J
, vol.12
, pp. 1713-1723
-
-
Li, J.J.1
Oberley, L.W.2
Fan, M.3
Colburn, N.H.4
-
49
-
-
0035062753
-
Invited review: Manganese superoxide dismutase in disease. Free Radic
-
[CrossRef] [PubMed]
-
Macmillan-Crow, L.A.; Cruthirds, D.L. Invited review: Manganese superoxide dismutase in disease. Free Radic. Res. 2001, 34, 325-336. [CrossRef] [PubMed]
-
(2001)
Res
, vol.34
, pp. 325-336
-
-
Macmillan-Crow, L.A.1
Cruthirds, D.L.2
-
50
-
-
84955313859
-
Mitochondrial superoxide dismutase has a protumorigenic role in ovarian clear cell carcinoma
-
[CrossRef] [PubMed]
-
Hemachandra, L.P.; Shin, D.H.; Dier, U.; Iuliano, J.N.; Engelberth, S.A.; Uusitalo, L.M.; Murphy, S.K.; Hempel, N. Mitochondrial superoxide dismutase has a protumorigenic role in ovarian clear cell carcinoma. Cancer Res. 2015, 75, 4973-4984. [CrossRef] [PubMed]
-
(2015)
Cancer Res
, vol.75
, pp. 4973-4984
-
-
Hemachandra, L.P.1
Shin, D.H.2
Dier, U.3
Iuliano, J.N.4
Engelberth, S.A.5
Uusitalo, L.M.6
Murphy, S.K.7
Hempel, N.8
-
51
-
-
84923169953
-
MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer
-
[CrossRef] [PubMed]
-
Hart, P.C.; Mao, M.; de Abreu, A.L.; Ansenberger-Fricano, K.; Ekoue, D.N.; Ganini, D.; Kajdacsy-Balla, A.; Diamond, A.M.; Minshall, R.D.; Consolaro, M.E.; et al. MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer. Nat. Commun. 2015. [CrossRef] [PubMed]
-
(2015)
Nat. Commun
-
-
Hart, P.C.1
Mao, M.2
De Abreu, A.L.3
Ansenberger-Fricano, K.4
Ekoue, D.N.5
Ganini, D.6
Kajdacsy-Balla, A.7
Diamond, A.M.8
Minshall, R.D.9
Consolaro, M.E.10
-
52
-
-
36248973110
-
NF-kappa B-mediated adaptive resistance to ionizing radiation
-
[CrossRef] [PubMed]
-
Ahmed, K.M.; Li, J.J. NF-kappa B-mediated adaptive resistance to ionizing radiation. Free Radic. Biol. Med. 2008, 44, 1-13. [CrossRef] [PubMed]
-
(2008)
Free Radic. Biol. Med
, vol.44
, pp. 1-13
-
-
Ahmed, K.M.1
Li, J.J.2
-
53
-
-
80054760340
-
SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine
-
[CrossRef] [PubMed]
-
Murley, J.S.; Baker, K.L.; Miller, R.C.; Darga, T.E.; Weichselbaum, R.R.; Grdina, D.J. SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine. Free Radic. Biol. Med. 2011, 51, 1918-1925. [CrossRef] [PubMed]
-
(2011)
Free Radic. Biol. Med
, vol.51
, pp. 1918-1925
-
-
Murley, J.S.1
Baker, K.L.2
Miller, R.C.3
Darga, T.E.4
Weichselbaum, R.R.5
Grdina, D.J.6
-
54
-
-
85047685805
-
NF-kappaB-dependent MnSOD expression protects adenocarcinoma cells from TNF-alpha-induced apoptosis
-
[CrossRef] [PubMed]
-
Delhalle, S.; Deregowski, V.; Benoit, V.; Merville, M.P.; Bours, V. NF-kappaB-dependent MnSOD expression protects adenocarcinoma cells from TNF-alpha-induced apoptosis. Oncogene 2002, 21, 3917-3924. [CrossRef] [PubMed]
-
(2002)
Oncogene
, vol.21
, pp. 3917-3924
-
-
Delhalle, S.1
Deregowski, V.2
Benoit, V.3
Merville, M.P.4
Bours, V.5
-
55
-
-
0032557458
-
Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1
-
[CrossRef] [PubMed]
-
Manna, S.K.; Zhang, H.J.; Yan, T.; Oberley, L.W.; Aggarwal, B.B. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1. J. Biol. Chem. 1998, 273, 13245-13254. [CrossRef] [PubMed]
-
(1998)
J. Biol. Chem
, vol.273
, pp. 13245-13254
-
-
Manna, S.K.1
Zhang, H.J.2
Yan, T.3
Oberley, L.W.4
Aggarwal, B.B.5
-
56
-
-
84879860923
-
Does scavenging of mitochondrial superoxide attenuate cancer prosurvival signaling pathways?
-
[CrossRef] [PubMed]
-
Nazarewicz, R.R.; Dikalova, A.; Bikineyeva, A.; Ivanov, S.; Kirilyuk, I.A.; Grigor'ev, I.A.; Dikalov, S.I. Does scavenging of mitochondrial superoxide attenuate cancer prosurvival signaling pathways? Antioxid. Redox Signal. 2013, 19, 344-349. [CrossRef] [PubMed]
-
(2013)
Antioxid. Redox Signal
, vol.19
, pp. 344-349
-
-
Nazarewicz, R.R.1
Dikalova, A.2
Bikineyeva, A.3
Ivanov, S.4
Kirilyuk, I.A.5
Grigor'ev, I.A.6
Dikalov, S.I.7
-
57
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
[CrossRef] [PubMed]
-
Qiu, X.; Brown, K.; Hirschey, M.D.; Verdin, E.; Chen, D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. 2010, 12, 662-627. [CrossRef] [PubMed]
-
(2010)
Cell Metab
, vol.12
, pp. 627-662
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
58
-
-
78650248160
-
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
-
[CrossRef] [PubMed]
-
Tao, R.; Coleman, M.C.; Pennington, J.D.; Ozden, O.; Park, S.H.; Jiang, H.; Kim, H.S.; Flynn, C.R.; Hill, S.; Hayes McDonald W.; et al. Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Mol. Cell 2010, 40, 893-904. [CrossRef] [PubMed]
-
(2010)
Mol. Cell
, vol.40
, pp. 893-904
-
-
Tao, R.1
Coleman, M.C.2
Pennington, J.D.3
Ozden, O.4
Park, S.H.5
Jiang, H.6
Kim, H.S.7
Flynn, C.R.8
Hill, S.9
McDonald, H.10
-
59
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization
-
[CrossRef] [PubMed]
-
Finley, L.W.; Carracedo, A.; Lee, J.; Souza, A.; Egia, A.; Zhang, J.; Teruya-Feldstein, J.; Moreira, P.I.; Cardoso, S.M.; Clish, C.B.; et al. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization. Cancer Cell 2011, 19, 416-428. [CrossRef] [PubMed]
-
(2011)
Cancer Cell
, vol.19
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
Souza, A.4
Egia, A.5
Zhang, J.6
Teruya-Feldstein, J.7
Moreira, P.I.8
Cardoso, S.M.9
Clish, C.B.10
-
60
-
-
74049094817
-
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
[CrossRef] [PubMed]
-
Kim, H.S.; Patel, K.; Muldoon-Jacobs, K.; Bisht, K.S.; Aykin-Burns, N.; Pennington, J.D.; van der Meer, R.; Nguyen, P.; Savage, J.; Owens, K.M.; et al. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 2010, 17, 41-52. [CrossRef] [PubMed]
-
(2010)
Cancer Cell
, vol.17
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon-Jacobs, K.3
Bisht, K.S.4
Aykin-Burns, N.5
Pennington, J.D.6
Van Der Meer, R.7
Nguyen, P.8
Savage, J.9
Owens, K.M.10
-
61
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
[CrossRef] [PubMed]
-
Hirschey, M.D.; Shimazu, T.; Goetzman, E.; Jing, E.; Schwer, B.; Lombard, D.B.; Grueter, C.A.; Harris, C.; Biddinger, S.; Ilkayeva, O.R.; et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 2010, 464, 121-125. [CrossRef] [PubMed]
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
-
62
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
[CrossRef] [PubMed]
-
Sundaresan, N.R.; Samant, S.A.; Pillai, V.B.; Rajamohan, S.B.; Gupta, M.P. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol. Cell Biol. 2008, 28, 6384-6401. [CrossRef] [PubMed]
-
(2008)
Mol. Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
63
-
-
79959819034
-
SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production
-
[CrossRef] [PubMed]
-
Bell, E.L.; Emerling, B.M.; Ricoult, S.J.; Guarente, L. SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production. Oncogene 2011, 30, 2986-2996. [CrossRef] [PubMed]
-
(2011)
Oncogene
, vol.30
, pp. 2986-2996
-
-
Bell, E.L.1
Emerling, B.M.2
Ricoult, S.J.3
Guarente, L.4
-
64
-
-
49349116124
-
Glutaredoxin systems
-
[CrossRef] [PubMed]
-
Lillig, C.H.; Berndt, C.; Holmgren, A. Glutaredoxin systems. Biochim. Biophys. Acta 2008, 1780, 1304-1317. [CrossRef] [PubMed]
-
(2008)
Biochim. Biophys. Acta
, vol.1780
, pp. 1304-1317
-
-
Lillig, C.H.1
Berndt, C.2
Holmgren, A.3
-
65
-
-
18344390036
-
Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes
-
[CrossRef] [PubMed]
-
Fratelli, M.; Demol, H.; Puype, M.; Casagrande, S.; Eberini, I.; Salmona, M.; Bonetto, V.; Mengozzi, M.; Duffieux, F.; Miclet, E. Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes. Proc. Natl. Acad. Sci. USA 2002, 99, 3505-3510. [CrossRef] [PubMed]
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3505-3510
-
-
Fratelli, M.1
Demol, H.2
Puype, M.3
Casagrande, S.4
Eberini, I.5
Salmona, M.6
Bonetto, V.7
Mengozzi, M.8
Duffieux, F.9
Miclet, E.10
-
66
-
-
78649668520
-
Oxidative stress inhibits vascular K(ATP) channels by S-glutathionylation
-
[CrossRef] [PubMed]
-
Yang, Y.; Shi, W.; Cui, N.; Wu, Z.; Jiang, C. Oxidative stress inhibits vascular K(ATP) channels by S-glutathionylation. J. Biol. Chem. 2010, 285, 38641-38648. [CrossRef] [PubMed]
-
(2010)
J. Biol. Chem
, vol.285
, pp. 38641-38648
-
-
Yang, Y.1
Shi, W.2
Cui, N.3
Wu, Z.4
Jiang, C.5
-
67
-
-
54049146740
-
Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: Potential role of CYS residues in decreasing oxidative damage
-
[CrossRef] [PubMed]
-
Hurd, T.R.; Requejo, R.; Filipovska, A.; Brown, S.; Prime, T.A.; Robinson, A.J.; Fearnley, I.M.; Murphy, M.P. Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: Potential role of CYS residues in decreasing oxidative damage. Js. Biol. Chem. 2008, 283, 24801-24815. [CrossRef] [PubMed]
-
(2008)
Js. Biol. Chem
, vol.283
, pp. 24801-24815
-
-
Hurd, T.R.1
Requejo, R.2
Filipovska, A.3
Brown, S.4
Prime, T.A.5
Robinson, A.J.6
Fearnley, I.M.7
Murphy, M.P.8
-
68
-
-
9144249116
-
Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: Implications for mitochondrial redox regulation and antioxidant DEFENSE
-
[CrossRef] [PubMed]
-
Beer, S.M.; Taylor, E.R.; Brown, S.E.; Dahm, C.C.; Costa, N.J.; Runswick, M.J.; Murphy, M.P. Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE. J. Biol. Chem. 2004, 279, 47939-47951. [CrossRef] [PubMed]
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47939-47951
-
-
Beer, S.M.1
Taylor, E.R.2
Brown, S.E.3
Dahm, C.C.4
Costa, N.J.5
Runswick, M.J.6
Murphy, M.P.7
-
69
-
-
58749103645
-
Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2
-
[CrossRef] [PubMed]
-
Diotte, N.M.; Xiong, Y.; Gao, J.; Chua, B.H.; Ho, Y.S. Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2. Biochim. Biophys. Acta 2009, 1793, 427-438. [CrossRef] [PubMed]
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 427-438
-
-
Diotte, N.M.1
Xiong, Y.2
Gao, J.3
Chua, B.H.4
Ho, Y.S.5
-
70
-
-
84901445668
-
Glutaredoxin-2 is required to control oxidative phosphorylation in cardiac muscle by mediating deglutathionylation reactions
-
[CrossRef] [PubMed]
-
Mailloux, R.J.; Xuan, J.Y.; McBride, S.; Maharsy, W.; Thorn, S.; Holterman, C.E.; Kennedy, C.R.; Rippstein, P.; deKemp, R.; da Silva, J.; et al. Glutaredoxin-2 is required to control oxidative phosphorylation in cardiac muscle by mediating deglutathionylation reactions. J. Biol. Chem. 2014, 289, 14812-14828. [CrossRef] [PubMed]
-
(2014)
J. Biol. Chem
, vol.289
, pp. 14812-14828
-
-
Mailloux, R.J.1
Xuan, J.Y.2
McBride, S.3
Maharsy, W.4
Thorn, S.5
Holterman, C.E.6
Kennedy, C.R.7
Rippstein, P.8
Dekemp, R.9
Da Silva, J.10
-
71
-
-
84855501167
-
Vertebrate-specific glutaredoxin is essential for brain development
-
[CrossRef] [PubMed]
-
Brautigam, L.; Xuan, J.Y.; McBride, S.; Maharsy, W.; Thorn, S.; Holterman, C.E.; Kennedy, C.R.; Rippstein, P.; deKemp, R.; da Silva, J.; et al. Vertebrate-specific glutaredoxin is essential for brain development. Proc. Natl. Acad. Sci. USA 2011, 108, 20532-20537. [CrossRef] [PubMed]
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 20532-20537
-
-
Brautigam, L.1
Xuan, J.Y.2
McBride, S.3
Maharsy, W.4
Thorn, S.5
Holterman, C.E.6
Kennedy, C.R.7
Rippstein, P.8
Dekemp, R.9
Da Silva, J.10
-
72
-
-
4444337091
-
Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide
-
[CrossRef] [PubMed]
-
Lillig, C.H.; Lönn, M.E.; Enoksson, M.; Fernandes, A.P.; Holmgren, A. Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide. Proc. Natl. Acad. Sci. USA 2004, 101, 13227-13232. [CrossRef] [PubMed]
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 13227-13232
-
-
Lillig, C.H.1
Lönn, M.E.2
Enoksson, M.3
Fernandes, A.P.4
Holmgren, A.5
-
73
-
-
11844265406
-
Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release
-
[CrossRef] [PubMed]
-
Enoksson, M.; Fernandes, A.P.; Prast, S.; Lillig, C.H.; Holmgren, A.; Orrenius, S. Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release. Biochem. Biophys. Res. Commun. 2005, 327, 774-779. [CrossRef] [PubMed]
-
(2005)
Biochem. Biophys. Res. Commun
, vol.327
, pp. 774-779
-
-
Enoksson, M.1
Fernandes, A.P.2
Prast, S.3
Lillig, C.H.4
Holmgren, A.5
Orrenius, S.6
-
74
-
-
33644641847
-
Catalase reverses tumorigenicity in a malignant cell line by an epidermal growth factor receptor pathway
-
[CrossRef] [PubMed]
-
Finch, J.S.; Tome, M.E.; Kwei, K.A.; Bowden, G.T. Catalase reverses tumorigenicity in a malignant cell line by an epidermal growth factor receptor pathway. Free Radic. Biol. Med. 2006, 40, 863-875. [CrossRef] [PubMed]
-
(2006)
Free Radic. Biol. Med
, vol.40
, pp. 863-875
-
-
Finch, J.S.1
Tome, M.E.2
Kwei, K.A.3
Bowden, G.T.4
-
75
-
-
0035937771
-
Scavenging of extracellular H2O2 by catalase inhibits the proliferation of HER-2/Neu-transformed rat-1 fibroblasts through the induction of a stress response
-
[CrossRef] [PubMed]
-
Preston, T.J.; Muller, W.J.; Singh, G. Scavenging of extracellular H2O2 by catalase inhibits the proliferation of HER-2/Neu-transformed rat-1 fibroblasts through the induction of a stress response. J. Biol. Chem. 2001, 276, 9558-9564. [CrossRef] [PubMed]
-
(2001)
J. Biol. Chem
, vol.276
, pp. 9558-9564
-
-
Preston, T.J.1
Muller, W.J.2
Singh, G.3
-
76
-
-
66449110388
-
Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses
-
[CrossRef] [PubMed]
-
Handy, D.E.; Lubos, E.; Yang, Y.; Galbraith, J.D.; Kelly, N.; Zhang, Y.Y.; Leopold, J.A.; Loscalzo, J. Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses. J. Biol. Chem. 2009, 284, 11913-11921. [CrossRef] [PubMed]
-
(2009)
J. Biol. Chem
, vol.284
, pp. 11913-11921
-
-
Handy, D.E.1
Lubos, E.2
Yang, Y.3
Galbraith, J.D.4
Kelly, N.5
Zhang, Y.Y.6
Leopold, J.A.7
Loscalzo, J.8
-
77
-
-
2942667688
-
Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase
-
[CrossRef] [PubMed]
-
McClung, J.P.; Roneker, C.A.; Mu, W.; Lisk, D.J.; Langlais, P.; Liu, F.; Lei, X.G. Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase. Proc. Natl. Acad. Sci. USA 2004, 101, 8852-8857. [CrossRef] [PubMed]
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8852-8857
-
-
McClung, J.P.1
Roneker, C.A.2
Mu, W.3
Lisk, D.J.4
Langlais, P.5
Liu, F.6
Lei, X.G.7
-
78
-
-
0034660880
-
The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase
-
[PubMed]
-
Li, S.; Yan, T.; Yang, J.Q.; Oberley, T.D.; Oberley, L.W. The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res. 2000, 60, 3927-3939. [PubMed]
-
(2000)
Cancer Res
, vol.60
, pp. 3927-3939
-
-
Li, S.1
Yan, T.2
Yang, J.Q.3
Oberley, T.D.4
Oberley, L.W.5
-
79
-
-
84922805618
-
Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth
-
[CrossRef] [PubMed]
-
Jin, L.; Li, D.; Alesi, G.N.; Fan, J.; Kang, H.B.; Lu, Z.; Boggon, T.J.; Jin, P.; Yi, H.; Wright, E.R.; et al. Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. Cancer Cell 2015, 27, 257-270. [CrossRef] [PubMed]
-
(2015)
Cancer Cell
, vol.27
, pp. 257-270
-
-
Jin, L.1
Li, D.2
Alesi, G.N.3
Fan, J.4
Kang, H.B.5
Lu, Z.6
Boggon, T.J.7
Jin, P.8
Yi, H.9
Wright, E.R.10
-
80
-
-
84894505732
-
Single-nucleotide polymorphisms of GPX1 and MnSOD and susceptibility to bladder cancer: A systematic review and meta-analysis
-
[CrossRef] [PubMed]
-
Cao, M.; Mu, X.; Jiang, C.; Yang, G.; Chen, H.; Xue, W. Single-nucleotide polymorphisms of GPX1 and MnSOD and susceptibility to bladder cancer: a systematic review and meta-analysis. Tumour. Biol. 2014, 35, 759-764. [CrossRef] [PubMed]
-
(2014)
Tumour. Biol
, vol.35
, pp. 759-764
-
-
Cao, M.1
Mu, X.2
Jiang, C.3
Yang, G.4
Chen, H.5
Xue, W.6
-
81
-
-
84955476379
-
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
-
[CrossRef] [PubMed]
-
Canli, O.; Alankus, Y.B.; Grootjans, S.; Vegi, N.; Hültner, L.; Hoppe, P.S.; Schroeder, T.; Vandenabeele, P.; Bornkamm, G.W.; Greten, F.R. Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors. Blood 2016. [CrossRef] [PubMed]
-
(2016)
Blood
-
-
Canli, O.1
Alankus, Y.B.2
Grootjans, S.3
Vegi, N.4
Hültner, L.5
Hoppe, P.S.6
Schroeder, T.7
Vandenabeele, P.8
Bornkamm, G.W.9
Greten, F.R.10
-
82
-
-
50049133588
-
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death
-
[CrossRef] [PubMed]
-
Seiler, A.; Schneider, M.; Förster, H.; Roth, S.; Wirth, E.K.; Culmsee, C.; Plesnila, N.; Kremmer, E.; Rådmark, O.; Wurst, W.; et al. Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death. Cell Metab. 2008, 8, 237-248. [CrossRef] [PubMed]
-
(2008)
Cell Metab
, vol.8
, pp. 237-248
-
-
Seiler, A.1
Schneider, M.2
Förster, H.3
Roth, S.4
Wirth, E.K.5
Culmsee, C.6
Plesnila, N.7
Kremmer, E.8
Rådmark, O.9
Wurst, W.10
-
83
-
-
11244270281
-
Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis
-
[CrossRef] [PubMed]
-
Ran, Q.; Liang, H.; Gu, M.; Qi, W.; Walter, C.A.; Roberts, L.J.; Herman, B.; Richardson, A.; van Remmen, H. Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. J. Biol. Chem. 2004, 279, 55137-55146. [CrossRef] [PubMed]
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55137-55146
-
-
Ran, Q.1
Liang, H.2
Gu, M.3
Qi, W.4
Walter, C.A.5
Roberts, L.J.6
Herman, B.7
Richardson, A.8
Van Remmen, H.9
-
84
-
-
84879414710
-
Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2
-
[CrossRef] [PubMed]
-
Sengupta, A.; Lichti, U.F.; Carlson, B.A.; Cataisson, C.; Ryscavage, A.O.; Mikulec, C.; Conrad, M.; Fischer, S.M.; Hatfield, D.L.; Yuspa, S.H. Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2. J. Investig. Dermatol. 2013, 133, 1731-1741. [CrossRef] [PubMed]
-
(2013)
J. Investig. Dermatol
, vol.133
, pp. 1731-1741
-
-
Sengupta, A.1
Lichti, U.F.2
Carlson, B.A.3
Cataisson, C.4
Ryscavage, A.O.5
Mikulec, C.6
Conrad, M.7
Fischer, S.M.8
Hatfield, D.L.9
Yuspa, S.H.10
-
85
-
-
30744454042
-
Suppression of the malignant phenotype in pancreatic cancer by overexpression of phospholipid hydroperoxide glutathione peroxidase. Hum
-
[CrossRef] [PubMed]
-
Liu, J.; Du, J.; Zhang, Y.; Sun, W.; Smith, B.J.; Oberley, L.W.; Cullen, J.J. Suppression of the malignant phenotype in pancreatic cancer by overexpression of phospholipid hydroperoxide glutathione peroxidase. Hum. Gene Ther. 2006, 17, 105-116. [CrossRef] [PubMed]
-
(2006)
Gene Ther
, vol.17
, pp. 105-116
-
-
Liu, J.1
Du, J.2
Zhang, Y.3
Sun, W.4
Smith, B.J.5
Oberley, L.W.6
Cullen, J.J.7
-
86
-
-
34249790862
-
Phospholipid hydroperoxide glutathione peroxidase (PHGPx) expression is downregulated in poorly differentiated breast invasive ductal carcinoma
-
[CrossRef] [PubMed]
-
Cejas, P.; García-Cabezas, M.A.; Casado, E.; Belda-Iniesta, C.; de Castro, J.; Fresno, J.A.; Sereno, M.; Barriuso, J.; Espinosa, E.; Zamora, P.; et al. Phospholipid hydroperoxide glutathione peroxidase (PHGPx) expression is downregulated in poorly differentiated breast invasive ductal carcinoma. Free Radic. Res. 2007, 41, 681-687. [CrossRef] [PubMed]
-
(2007)
Free Radic. Res
, vol.41
, pp. 681-687
-
-
Cejas, P.1
García-Cabezas, M.A.2
Casado, E.3
Belda-Iniesta, C.4
De Castro, J.5
Fresno, J.A.6
Sereno, M.7
Barriuso, J.8
Espinosa, E.9
Zamora, P.10
-
87
-
-
30344435321
-
Blocking tumor cell eicosanoid synthesis by GP x 4 impedes tumor growth and malignancy. Free Radic
-
[CrossRef] [PubMed]
-
Heirman, I.; Ginneberge, D.; Brigelius-Flohé, R.; Hendrickx, N.; Agostinis, P.; Brouckaert, P.; Rottiers, P.; Grooten, J. Blocking tumor cell eicosanoid synthesis by GP x 4 impedes tumor growth and malignancy. Free Radic. Biol. Med. 2006, 40, 285-294. [CrossRef] [PubMed]
-
(2006)
Biol. Med
, vol.40
, pp. 285-294
-
-
Heirman, I.1
Ginneberge, D.2
Brigelius-Flohé, R.3
Hendrickx, N.4
Agostinis, P.5
Brouckaert, P.6
Rottiers, P.7
Grooten, J.8
-
88
-
-
22044433408
-
NF-kappaB, Nrf2, and HO-1 interplay in redox-regulated VCAM-1 expression
-
[CrossRef] [PubMed]
-
Banning, A.; Brigelius-Flohe, R. NF-kappaB, Nrf2, and HO-1 interplay in redox-regulated VCAM-1 expression. Antioxid. Redox Signal. 2005, 7, 889-899. [CrossRef] [PubMed]
-
(2005)
Antioxid. Redox Signal
, vol.7
, pp. 889-899
-
-
Banning, A.1
Brigelius-Flohe, R.2
-
89
-
-
84892685001
-
Regulation of ferroptotic cancer cell death by GPX4
-
[CrossRef] [PubMed]
-
Yang, W.S.; SriRamaratnam, R.; Welsch, M.E.; Shimada, K.; Skouta, R.; Viswanathan, V.S.; Cheah, J.H.; Clemons, P.A.; Shamji, A.F.; Clish, C.B.; et al. Regulation of ferroptotic cancer cell death by GPX4. Cell 2014, 156, 317-331. [CrossRef] [PubMed]
-
(2014)
Cell
, vol.156
, pp. 317-331
-
-
Yang, W.S.1
Sriramaratnam, R.2
Welsch, M.E.3
Shimada, K.4
Skouta, R.5
Viswanathan, V.S.6
Cheah, J.H.7
Clemons, P.A.8
Shamji, A.F.9
Clish, C.B.10
-
90
-
-
84903380277
-
Plasma antioxidants, genetic variation in SOD2, CAT, GPX1, GPX4, and prostate cancer survival
-
[CrossRef] [PubMed]
-
Van Blarigan, E.L.; Ma, J.; Kenfield, S.A.; Stampfer, M.J.; Sesso, H.D.; Giovannucci, E.L.; Witte, J.S.; Erdman, J.W., Jr.; Chan, J.M.; Penney, K.L. Plasma antioxidants, genetic variation in SOD2, CAT, GPX1, GPX4, and prostate cancer survival. Cancer Epidemiol. Biomarkers Prev. 2014, 23, 1037-1046. [CrossRef] [PubMed]
-
(2014)
Cancer Epidemiol. Biomarkers Prev
, vol.23
, pp. 1037-1046
-
-
Van Blarigan, E.L.1
Ma, J.2
Kenfield, S.A.3
Stampfer, M.J.4
Sesso, H.D.5
Giovannucci, E.L.6
Witte, J.S.7
Erdman, J.W.8
Chan, J.M.9
Penney, K.L.10
-
91
-
-
0031028975
-
And expression of a novel mammalian thioredoxin
-
[CrossRef] [PubMed]
-
Spyrou, G.; Enmark, E.; Miranda-Vizuete, A.; Gustafsson, J. Cloning and expression of a novel mammalian thioredoxin. J. Biol. Chem. 1997, 272, 2936-2941. [CrossRef] [PubMed]
-
(1997)
J. Biol. Chem
, vol.272
, pp. 2936-2941
-
-
Spyrou, G.1
Enmark, E.2
Miranda-Vizuete, A.3
Gustafsson, J.4
-
92
-
-
0032830405
-
CDNA cloning, expression and chromosomal localization of the mouse mitochondrial thioredoxin reductase gene (1)
-
[CrossRef]
-
Miranda-Vizuete, A.; Damdimopoulos, A.E.; Spyrou, G. cDNA cloning, expression and chromosomal localization of the mouse mitochondrial thioredoxin reductase gene (1). Biochim. Biophys. Acta 1999, 1447, 113-118. [CrossRef]
-
(1999)
Biochim. Biophys. Acta
, vol.1447
, pp. 113-118
-
-
Miranda-Vizuete, A.1
Damdimopoulos, A.E.2
Spyrou, G.3
-
93
-
-
2942696470
-
Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner
-
[CrossRef] [PubMed]
-
Zhang, R.; Al-Lamki, R.; Bai, L.; Streb, J.W.; Miano, J.M.; Bradley, J.; Min, W. Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner. Circ. Res. 2004, 94, 1483-1491. [CrossRef] [PubMed]
-
(2004)
Circ. Res
, vol.94
, pp. 1483-1491
-
-
Zhang, R.1
Al-Lamki, R.2
Bai, L.3
Streb, J.W.4
Miano, J.M.5
Bradley, J.6
Min, W.7
-
94
-
-
0001445231
-
Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin
-
[CrossRef]
-
Chae, H.Z.; Kim, H.J.; Kang, S.W.; Rhee, S.G. Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin. Diabetes Res. Clin. Pr. 1999, 45, 101-112. [CrossRef]
-
(1999)
Diabetes Res. Clin. Pr
, vol.45
, pp. 101-112
-
-
Chae, H.Z.1
Kim, H.J.2
Kang, S.W.3
Rhee, S.G.4
-
95
-
-
0034534165
-
Antioxidant function of thioredoxin and glutaredoxin systems
-
[CrossRef] [PubMed]
-
Holmgren, A. Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid. Redox Signal. 2000, 2, 811-820. [CrossRef] [PubMed]
-
(2000)
Antioxid. Redox Signal
, vol.2
, pp. 811-820
-
-
Holmgren, A.1
-
96
-
-
33744809562
-
Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-alpha-induced reactive oxygen species generation, NF-kappaB activation, and apoptosis
-
[CrossRef] [PubMed]
-
Hansen, J.M.; Zhang, H.; Jones, D.P. Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-alpha-induced reactive oxygen species generation, NF-kappaB activation, and apoptosis. Toxicol. Sci. 2006, 91, 643-650. [CrossRef] [PubMed]
-
(2006)
Toxicol. Sci
, vol.91
, pp. 643-650
-
-
Hansen, J.M.1
Zhang, H.2
Jones, D.P.3
-
97
-
-
0037031899
-
Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death
-
[CrossRef] [PubMed]
-
Damdimopoulos, A.E.; Miranda-Vizuete, A.; Pelto-Huikko, M.; Gustafsson, J.A.; Spyrou, G. Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death. J. Biol. Chem. 2002, 277, 33249-33257. [CrossRef] [PubMed]
-
(2002)
J. Biol. Chem
, vol.277
, pp. 33249-33257
-
-
Damdimopoulos, A.E.1
Miranda-Vizuete, A.2
Pelto-Huikko, M.3
Gustafsson, J.A.4
Spyrou, G.5
-
98
-
-
33646355972
-
Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells
-
[CrossRef] [PubMed]
-
Wang, D.; Masutani, H.; Oka, S.; Tanaka, T.; Yamaguchi-Iwai, Y.; Nakamura, H.; Yodoi, J. Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells. J. Biol. Chem. 2006, 281, 7384-7391. [CrossRef] [PubMed]
-
(2006)
J. Biol. Chem
, vol.281
, pp. 7384-7391
-
-
Wang, D.1
Masutani, H.2
Oka, S.3
Tanaka, T.4
Yamaguchi-Iwai, Y.5
Nakamura, H.6
Yodoi, J.7
-
99
-
-
34147137668
-
Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha
-
[CrossRef] [PubMed]
-
Zhou, J.; Damdimopoulos, A.E.; Spyrou, G.; Brune, B. Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha. J. Biol. Chem. 2007, 282, 7482-7490. [CrossRef] [PubMed]
-
(2007)
J. Biol. Chem
, vol.282
, pp. 7482-7490
-
-
Zhou, J.1
Damdimopoulos, A.E.2
Spyrou, G.3
Brune, B.4
-
100
-
-
44449119080
-
Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins
-
[CrossRef] [PubMed]
-
Benhar, M.; Forrester, M.T.; Hess, D.T.; Stamler, J.S. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 2008, 320, 1050-1054. [CrossRef] [PubMed]
-
(2008)
Science
, vol.320
, pp. 1050-1054
-
-
Benhar, M.1
Forrester, M.T.2
Hess, D.T.3
Stamler, J.S.4
-
101
-
-
0037305881
-
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice
-
[CrossRef] [PubMed]
-
Nonn, L.; Williams, R.R.; Erickson, R.P.; Powis, G. The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice. Mol. Cell. Biol. 2003, 23, 916-922. [CrossRef] [PubMed]
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 916-922
-
-
Nonn, L.1
Williams, R.R.2
Erickson, R.P.3
Powis, G.4
-
102
-
-
39149137166
-
Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress
-
[CrossRef] [PubMed]
-
Perez, V.I.; Lew, C.M.; Cortez, L.A.; Webb, C.R.; Rodriguez, M.; Liu, Y.; Qi, W.; Li, Y.; Chaudhuri, A.; van Remmen, H.; et al. Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress. Free Radic. Biol. Med. 2008, 44, 882-892. [CrossRef] [PubMed]
-
(2008)
Free Radic. Biol. Med
, vol.44
, pp. 882-892
-
-
Perez, V.I.1
Lew, C.M.2
Cortez, L.A.3
Webb, C.R.4
Rodriguez, M.5
Liu, Y.6
Qi, W.7
Li, Y.8
Chaudhuri, A.9
Van Remmen, H.10
-
103
-
-
34247895799
-
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions
-
[CrossRef] [PubMed]
-
Zhang, H.; Luo, Y.; Zhang, W.; He, Y.; Dai, S.; Zhang, R.; Huang, Y.; Bernatchez, P.; Giordano, F.J.; Shadel, G.; et al. Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Am. J. Pathol. 2007, 170, 1108-1120. [CrossRef] [PubMed]
-
(2007)
Am. J. Pathol
, vol.170
, pp. 1108-1120
-
-
Zhang, H.1
Luo, Y.2
Zhang, W.3
He, Y.4
Dai, S.5
Zhang, R.6
Huang, Y.7
Bernatchez, P.8
Giordano, F.J.9
Shadel, G.10
-
104
-
-
63449128721
-
Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis
-
[CrossRef] [PubMed]
-
Dai, S.; He, Y.; Zhang, H.; Yu, L.; Wan, T.; Xu, Z.; Jones, D.; Chen, H.; Min, W. Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis. Arterioscler. Thromb. Vasc. Biol. 2009, 29, 495-502. [CrossRef] [PubMed]
-
(2009)
Arterioscler. Thromb. Vasc. Biol
, vol.29
, pp. 495-502
-
-
Dai, S.1
He, Y.2
Zhang, H.3
Yu, L.4
Wan, T.5
Xu, Z.6
Jones, D.7
Chen, H.8
Min, W.9
-
105
-
-
84929503093
-
Thioredoxin-2 Inhibits Mitochondrial ROS Generation and ASK1 Activity to Maintain Cardiac Function
-
[CrossRef] [PubMed]
-
Huang, Q.; Zhou, H.J.; Zhang, H.; Huang, Y.; Hinojosa-Kirschenbaum, F.; Fan, P.; Yao, L.; Belardinelli, L.; Tellides, G.; Giordano, F.J.; et al. Thioredoxin-2 Inhibits Mitochondrial ROS Generation and ASK1 Activity to Maintain Cardiac Function. Circulation 2015, 24, 1082-1097. [CrossRef] [PubMed]
-
(2015)
Circulation
, vol.24
, pp. 1082-1097
-
-
Huang, Q.1
Zhou, H.J.2
Zhang, H.3
Huang, Y.4
Hinojosa-Kirschenbaum, F.5
Fan, P.6
Yao, L.7
Belardinelli, L.8
Tellides, G.9
Giordano, F.J.10
-
106
-
-
33751181030
-
On the potential of thioredoxin reductase inhibitors for cancer therapy
-
[CrossRef] [PubMed]
-
Urig, S.; Becker, K. On the potential of thioredoxin reductase inhibitors for cancer therapy. Semin. Cancer Biol. 2006, 16, 452-465. [CrossRef] [PubMed]
-
(2006)
Semin. Cancer Biol
, vol.16
, pp. 452-465
-
-
Urig, S.1
Becker, K.2
-
107
-
-
84953345297
-
Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells
-
[CrossRef] [PubMed]
-
Fink, E.E.; Mannava, S.; Bagati, A.; Bianchi-Smiraglia, A.; Nair, J.R.; Moparthy, K.; Lipchick, B.C.; Drokov, M.; Utley, A.; Ross, J.; et al. Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells. Leukemia 2016, 30, 104-111. [CrossRef] [PubMed]
-
(2016)
Leukemia
, vol.30
, pp. 104-111
-
-
Fink, E.E.1
Mannava, S.2
Bagati, A.3
Bianchi-Smiraglia, A.4
Nair, J.R.5
Moparthy, K.6
Lipchick, B.C.7
Drokov, M.8
Utley, A.9
Ross, J.10
-
108
-
-
27144548880
-
Mechanisms of cytotoxicity of selected organogold(III) compounds
-
[CrossRef] [PubMed]
-
Coronnello, M.; Mini, E.; Caciagli, B.; Cinellu, M.A.; Bindoli, A.; Gabbiani, C.; Messori, L. Mechanisms of cytotoxicity of selected organogold(III) compounds. J. Med. Chem. 2005, 48, 6761-6765. [CrossRef] [PubMed]
-
(2005)
J. Med. Chem
, vol.48
, pp. 6761-6765
-
-
Coronnello, M.1
Mini, E.2
Caciagli, B.3
Cinellu, M.A.4
Bindoli, A.5
Gabbiani, C.6
Messori, L.7
-
109
-
-
0037827160
-
Increased expression of mitochondrial peroxiredoxin-3 (Thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis
-
[PubMed]
-
Nonn, L.; Berggren, M.; Powis, G. Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis. Mol. Cancer Res. 2003, 1, 682-689. [PubMed]
-
(2003)
Mol. Cancer Res
, vol.1
, pp. 682-689
-
-
Nonn, L.1
Berggren, M.2
Powis, G.3
-
110
-
-
84930479572
-
The paradoxical role of thioredoxin on oxidative stress and aging
-
[CrossRef] [PubMed]
-
Cunningham, G.M.; Roman, M.G.; Flores, L.C.; Hubbard, G.B.; Salmon, A.B.; Zhang, Y.; Gelfond, J.; Ikeno, Y. The paradoxical role of thioredoxin on oxidative stress and aging. Arch. Biochem. Biophys. 2015, 576, 32-38. [CrossRef] [PubMed]
-
(2015)
Arch. Biochem. Biophys
, vol.576
, pp. 32-38
-
-
Cunningham, G.M.1
Roman, M.G.2
Flores, L.C.3
Hubbard, G.B.4
Salmon, A.B.5
Zhang, Y.6
Gelfond, J.7
Ikeno, Y.8
-
111
-
-
84905657679
-
Novel action and mechanism of auranofin in inhibition of vascular endothelial growth factor receptor-3-dependent lymphangiogenesis
-
[CrossRef] [PubMed]
-
Chen, X.; Zhou, H.J.; Huang, Q.; Lu, L.; Min,W. Novel action and mechanism of auranofin in inhibition of vascular endothelial growth factor receptor-3-dependent lymphangiogenesis. Anticancer Agents Med. Chem. 2014, 14, 946-954. [CrossRef] [PubMed]
-
(2014)
Anticancer Agents Med. Chem
, vol.14
, pp. 946-954
-
-
Chen, X.1
Zhou, H.J.2
Huang, Q.3
Lu, L.4
Min, W.5
-
112
-
-
84904893458
-
Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death
-
[CrossRef] [PubMed]
-
Ji, W.; Yang, M.; Praggastis, A.; Li, Y.; He, Y.; Ghazvinian, R.; Cincotta, D.; Rice, K.; Min, W. Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death. PLoS ONE 2014, 9, e103224. [CrossRef] [PubMed]
-
(2014)
Plos ONE
, vol.9
-
-
Ji, W.1
Yang, M.2
Praggastis, A.3
Li, Y.4
He, Y.5
Ghazvinian, R.6
Cincotta, D.7
Rice, K.8
Min, W.9
-
113
-
-
84890120295
-
Genetically encoded fluorescent redox sensors
-
[CrossRef] [PubMed]
-
Lukyanov, K.A.; Belousov, V.V. Genetically encoded fluorescent redox sensors. Biochim. Biophys. Acta 2014, 1840, 745-756. [CrossRef] [PubMed]
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 745-756
-
-
Lukyanov, K.A.1
Belousov, V.V.2
-
114
-
-
84901842374
-
Imaging dynamic redox processes with genetically encoded probes
-
[CrossRef] [PubMed]
-
Ezerina, D.; Morgan, B.; Dick, T.P. Imaging dynamic redox processes with genetically encoded probes. J. Mol. Cell Cardiol. 2014, 73, 43-49. [CrossRef] [PubMed]
-
(2014)
J. Mol. Cell Cardiol
, vol.73
, pp. 43-49
-
-
Ezerina, D.1
Morgan, B.2
Dick, T.P.3
-
115
-
-
84890774184
-
Hallmarks of a new era in mitochondrial biochemistry
-
[CrossRef] [PubMed]
-
Pagliarini, D.J.; Rutter, J. Hallmarks of a new era in mitochondrial biochemistry. Genes Dev. 2013, 27, 2615-2627. [CrossRef] [PubMed]
-
(2013)
Genes Dev
, vol.27
, pp. 2615-2627
-
-
Pagliarini, D.J.1
Rutter, J.2
-
116
-
-
84874956967
-
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging
-
[CrossRef] [PubMed]
-
Rhee, H.W.; Zou, P.; Udeshi, N.D.; Martell, J.D.; Mootha, V.K.; Carr, S.A.; Ting, A.Y. Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging. Science 2013, 339, 1328-1331. [CrossRef] [PubMed]
-
(2013)
Science
, vol.339
, pp. 1328-1331
-
-
Rhee, H.W.1
Zou, P.2
Udeshi, N.D.3
Martell, J.D.4
Mootha, V.K.5
Carr, S.A.6
Ting, A.Y.7
-
117
-
-
84956592033
-
Redox proteomics: Methods for the identification and enrichment of redox-modified proteins and their applications
-
[CrossRef] [PubMed]
-
Lennicke, C.; Rahn, J.; Heimer, N.; Lichtenfels, R.; Wessjohann, L.A.; Seliger, B. Redox proteomics: Methods for the identification and enrichment of redox-modified proteins and their applications. Proteomics 2016, 16, 197-213. [CrossRef] [PubMed]
-
(2016)
Proteomics
, vol.16
, pp. 197-213
-
-
Lennicke, C.1
Rahn, J.2
Heimer, N.3
Lichtenfels, R.4
Wessjohann, L.A.5
Seliger, B.6
-
118
-
-
84947561473
-
Data standards can boost metabolomics research, and if there is a will, there is a way
-
[CrossRef] [PubMed]
-
Rocca-Serra, P.; Salek, R.M.; Arita, M.; Correa, E.; Dayalan, S.; Gonzalez-Beltran, A.; Ebbels, T.; Goodacre, R.; Hastings, J.; Haug, K.; et al. Data standards can boost metabolomics research, and if there is a will, there is a way. Metabolomics 2016. [CrossRef] [PubMed]
-
(2016)
Metabolomics
-
-
Rocca-Serra, P.1
Salek, R.M.2
Arita, M.3
Correa, E.4
Dayalan, S.5
Gonzalez-Beltran, A.6
Ebbels, T.7
Goodacre, R.8
Hastings, J.9
Haug, K.10
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