Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth

Cancer Cell

Volumn 27, Issue 2, 2015, Pages 257-270

  Jin, Lingtao ^a   Li, Dan ^a   Alesi, Gina N ^a   Fan, Jun ^a   Kang, Hee Bum ^a   Lu, Zhou ^b,f   Boggon, Titus J ^c   Jin, Peng ^a   Yi, Hong ^d   Wright, Elizabeth R ^a   Duong, Duc ^a   Seyfried, Nicholas T ^a   Egnatchik, Robert ^e   DeBerardinis, Ralph J ^e   Magliocca, Kelly R ^a   He, Chuan ^b   Arellano, Martha L ^a   Khoury, J Hanna J ^a   Shin, Dong M ^a   Khuri, Fadlo R ^a   Kang, Sumin ^a   more..

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b THE UNIVERSITY OF CHICAGO   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d EMORY UNIVERSITY   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; FUMARIC ACID; GLUTAMATE DEHYDROGENASE; GLUTAMATE DEHYDROGENASE 1; GLUTATHIONE PEROXIDASE 1; UNCLASSIFIED DRUG; ALPHA-KETOGLUTARIC ACID; ANTIOXIDANT; FUMARIC ACID DERIVATIVE; GLUD1 PROTEIN, HUMAN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; FEMALE; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REDOX HOMEOSTASIS; TUMOR GROWTH; UPREGULATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARCINOGENESIS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; CARCINOGENESIS; FUMARATES; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTAMATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HUMANS; KETOGLUTARIC ACIDS; LEUKEMIA; MITOCHONDRIA; OXIDATION-REDUCTION; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84922805618     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2014.12.006     Document Type: Article

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