Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner

Circulation Research

Volumn 94, Issue 11, 2004, Pages 1483-1491

  Zhang, Rong ^a   Al Lamki, Rafia ^b   Bai, Lanfang ^a   Streb, Jeffrey W ^c   Miano, Joseph M ^c   Bradley, John ^b   Min, Wang ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF ROCHESTER   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; ASK1; Mitochondria; Thioredoxin; TNF

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOPTOSIS SIGNAL REGULATING KINASE 1; CYSTEINE; CYTOCHROME C; ENZYME INHIBITOR; GLUTATHIONE TRANSFERASE; JANUS KINASE; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; THIOREDOXIN 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; KNOCKOUT MOUSE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

ANTHRACENES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CYTOCHROMES C; CYTOPLASM; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASE 5; MEMBRANE PROTEINS; MITOCHONDRIA; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; THIOREDOXIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 2942696470     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000130525.37646.a7     Document Type: Article

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