-
1
-
-
0017165406
-
New oral gold compound for treatment of rheumatoid arthritis
-
Finkelstein, A.E.; Walz, D.T.; Batista, V.; Mizraji, M.; Roisman, F.; Misher, A. Auranofin. New oral gold compound for treatment of rheumatoid arthritis. Ann. Rheum. Dis., 1976, 35 (3), 251-257.
-
(1976)
Ann. Rheum. Dis
, vol.35
, Issue.3
, pp. 251-257
-
-
Finkelstein, A.E.1
Walz, D.T.2
Batista, V.3
Mizraji, M.4
Roisman, F.5
Misher, A.6
-
2
-
-
0030855880
-
Auranofin is safe and superior to placebo in elderly-onset rheumatoid arthritis
-
Glennas, A.; Kvien, T.K.; Andrup, O.; Clarke-Jenssen, O.; Karstensen, B.; Brodin, U. Auranofin is safe and superior to placebo in elderly-onset rheumatoid arthritis. British J. Rheum., 1997, 36(8), 870-877.
-
(1997)
British J. Rheum
, vol.36
, Issue.8
, pp. 870-877
-
-
Glennas, A.1
Kvien, T.K.2
Andrup, O.3
Clarke-Jenssen, O.4
Karstensen, B.5
Brodin, U.6
-
3
-
-
80055108291
-
Protein targets for anticancer gold compounds: Mechanistic inferences
-
Gabbiani, C.; Messori, L. Protein targets for anticancer gold compounds: Mechanistic inferences. Anti-Cancer Agents Curr. Med. Chem., 2011, 11 (10), 929-939.
-
(2011)
Anti-Cancer Agents Curr. Med. Chem
, vol.11
, Issue.10
, pp. 929-939
-
-
Gabbiani, C.1
Messori, L.2
-
4
-
-
80055080734
-
Molecular mechanisms and proposed targets for selected anticancer gold compounds
-
Casini, A.; Messori, L. Molecular mechanisms and proposed targets for selected anticancer gold compounds. Curr. Topics in Med. Chem., 2011, 11(21), 2647-2660.
-
(2011)
Curr. Topics In Med. Chem
, vol.11
, Issue.21
, pp. 2647-2660
-
-
Casini, A.1
Messori, L.2
-
5
-
-
0023275566
-
Inhibition of human endothelial cell proliferation by gold compounds
-
Matsubara, T.; Ziff, M. Inhibition of human endothelial cell proliferation by gold compounds. J.Clin. Invest.,1987, 79 (5), 1440-1446.
-
(1987)
J.Clin. Invest
, vol.79
, Issue.5
, pp. 1440-1446
-
-
Matsubara, T.1
Ziff, M.2
-
6
-
-
84872151251
-
The biological activity of auranofin: Implications for novel treatment of diseases
-
Madeira, J.M.; Gibson, D.L.; Kean, W.F.; Klegeris, A. The biological activity of auranofin: Implications for novel treatment of diseases. Inflammopharmacology, 2012, 20 (6), 297-306.
-
(2012)
Inflammopharmacology
, vol.20
, Issue.6
, pp. 297-306
-
-
Madeira, J.M.1
Gibson, D.L.2
Kean, W.F.3
Klegeris, A.4
-
7
-
-
70349658714
-
TNF-alphadrives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice
-
Baluk, P.; Yao, L.C.; Feng, J.; Romano, T.; Jung, S.S. Schreiter, J.L.; Yan, L.; Shealy, D.J.; McDonald, D.M. TNF-alphadrives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice. J. Clin. Invest., 2009, 119 (10), 2954-2964.
-
(2009)
J. Clin. Invest
, vol.119
, Issue.10
, pp. 2954-2964
-
-
Baluk, P.1
Yao, L.C.2
Feng, J.3
Romano, T.4
Jung, S.S.5
Schreiter, J.L.6
Yan, L.7
Shealy, D.J.8
McDonald, D.M.9
-
8
-
-
0035126049
-
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
-
Stacker, S.A.; Caesar, C.; Baldwin, M.E.; Thornton, G. E.; Williams, R.A.; Prevo, R.; Jackson, D.G.; Nishikawa, S.; Kubo, H.; Achen, M.G. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat. Med., 2001, 7(2), 186-191.
-
(2001)
Nat. Med
, vol.7
, Issue.2
, pp. 186-191
-
-
Stacker, S.A.1
Caesar, C.2
Baldwin, M.E.3
Thornton, G.E.4
Williams, R.A.5
Prevo, R.6
Jackson, D.G.7
Nishikawa, S.8
Kubo, H.9
Achen, M.G.10
-
9
-
-
17744390184
-
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
-
Mandriota, S.J.; Jussila, L.; Jeltsch, M.; Compagni, A.; Baetens, D. Prevo, R.; Banerji, S.; Huarte, J.; Montesano, R.; Jackson, D.G. Orci, L.; Alitalo, K.; Christofori, G.; Pepper, M.S. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. Embo. J., 2001, 20(4), 672-682.
-
(2001)
Embo. J
, vol.20
, Issue.4
, pp. 672-682
-
-
Mandriota, S.J.1
Jussila, L.2
Jeltsch, M.3
Compagni, A.4
Baetens, D.5
Prevo, R.6
Banerji, S.7
Huarte, J.8
Montesano, R.9
Jackson, D.G.10
Orci, L.11
Alitalo, K.12
Christofori, G.13
Pepper, M.S.14
-
10
-
-
73349086586
-
Restorative and rejection-associated lymphangiogenesis after renal transplantation: Friend or foe?
-
Vass, D.G.; Hughes, J.; Marson, L.P. Restorative and rejection-associated lymphangiogenesis after renal transplantation: Friend or foe? Transplantation, 2009, 88(11), 1237-1239.
-
(2009)
Transplantation
, vol.88
, Issue.11
, pp. 1237-1239
-
-
Vass, D.G.1
Hughes, J.2
Marson, L.P.3
-
11
-
-
75149113630
-
Lymphangiogenesis: In vitro and in vivo models
-
Bruyere, F.; Noel, A., Lymphangiogenesis: In vitro and in vivo models. FASEB J., 2010, 24(1), 8-21.
-
(2010)
FASEB J
, vol.24
, Issue.1
, pp. 8-21
-
-
Bruyere, F.1
Noel, A.2
-
12
-
-
56049090304
-
Inflammation, angiogenesis, and lymphangiogenesis
-
Halin, C.; Detmar, M. Inflammation, angiogenesis, and lymphangiogenesis. Methods Enzymol., 2008, 445, 1-25.
-
(2008)
Methods Enzymol
, vol.445
, pp. 1-25
-
-
Halin, C.1
Detmar, M.2
-
13
-
-
0033251028
-
Podoplanin--a specific marker for lymphatic endothelium expressed in angiosarcoma
-
Breiteneder-Geleff, S.; Soleiman, A.; Horvat, R.; Amann, G. Kowalski, H.; Kerjaschki, D. Podoplanin--a specific marker for lymphatic endothelium expressed in angiosarcoma. Verh. Dtsch. Ges. Pathol., 1999, 83, 270-275.
-
(1999)
Verh. Dtsch. Ges. Pathol
, vol.83
, pp. 270-275
-
-
Breiteneder-Geleff, S.1
Soleiman, A.2
Horvat, R.3
Amann, G.4
Kowalski, H.5
Kerjaschki, D.6
-
14
-
-
0033593793
-
LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan
-
Banerji, S.; Ni, J.; Wang, S.X.; Clasper, S.; Su, J.; Tammi, R. Jones, M.; Jackson, D.G. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J. Cell Biol., 1999, 144 (4), 789-801.
-
(1999)
J. Cell Biol
, vol.144
, Issue.4
, pp. 789-801
-
-
Banerji, S.1
Ni, J.2
Wang, S.X.3
Clasper, S.4
Su, J.5
Tammi, R.6
Jones, M.7
Jackson, D.G.8
-
15
-
-
41749093830
-
Molecular biology and pathology of lymphangiogenesis
-
Karpanen, T.; Alitalo, K. Molecular biology and pathology of lymphangiogenesis. Annu. Rev. Pathol., 2008, 3, 367-397.
-
(2008)
Annu. Rev. Pathol
, vol.3
, pp. 367-397
-
-
Karpanen, T.1
Alitalo, K.2
-
16
-
-
76749083490
-
Lymphangiogenesis: Molecular mechanisms and future promise
-
Tammela, T.; Alitalo, K. Lymphangiogenesis: Molecular mechanisms and future promise. Cell, 2010, 140 (4), 460-476.
-
(2010)
Cell
, vol.140
, Issue.4
, pp. 460-476
-
-
Tammela, T.1
Alitalo, K.2
-
17
-
-
0028938746
-
Expression of the fmslike tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
-
Kaipainen, A.; Korhonen, J.; Mustonen, T.; Van Hinsbergh, V.W.; Fang, G. H.; Dumont, D.; Breitman, M.; Alitalo, K. Expression of the fmslike tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc. Natl. Acad. Sci. USA, 1995, 92(8), 3566-3570.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, Issue.8
, pp. 3566-3570
-
-
Kaipainen, A.1
Korhonen, J.2
Mustonen, T.3
van Hinsbergh, V.W.4
Fang, G.H.5
Dumont, D.6
Breitman, M.7
Alitalo, K.8
-
18
-
-
0032933883
-
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
-
Valtola, R.; Salven, P.; Heikkila, P.; Taipale, J.; Joensuu, H. Rehn, M.; Pihlajaniemi, T.; Weich, H.; DeWaal, R.; Alitalo, K. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer. Am. J.Pathol., 1999, 154(5), 1381-1390.
-
(1999)
Am. J.Pathol
, vol.154
, Issue.5
, pp. 1381-1390
-
-
Valtola, R.1
Salven, P.2
Heikkila, P.3
Taipale, J.4
Joensuu, H.5
Rehn, M.6
Pihlajaniemi, T.7
Weich, H.8
Dewaal, R.9
Alitalo, K.10
-
19
-
-
0033846016
-
Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing
-
Paavonen, K.; Puolakkainen, P.; Jussila, L.; Jahkola, T.; Alitalo, K. Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing. Am. J. Pathol., 2000, 156 (5), 1499-1504.
-
(2000)
Am. J. Pathol
, vol.156
, Issue.5
, pp. 1499-1504
-
-
Paavonen, K.1
Puolakkainen, P.2
Jussila, L.3
Jahkola, T.4
Alitalo, K.5
-
20
-
-
80054040080
-
An overview of lymphatic vessels and their emerging role in cardiovascular disease
-
Jones, D.; Min, W. An overview of lymphatic vessels and their emerging role in cardiovascular disease. J. Cardiovasc. Dis. Res., 2011, 2(3), 141-152.
-
(2011)
J. Cardiovasc. Dis. Res
, vol.2
, Issue.3
, pp. 141-152
-
-
Jones, D.1
Min, W.2
-
21
-
-
84894568529
-
Lymphangiogenesis and lymphatic vessel remodelling in cancer
-
Stacker, S.A.; Williams, S.P.; Karnezis, T. Shayan, R.; Fox, S.B.; Achen, M.G. Lymphangiogenesis and lymphatic vessel remodelling in cancer. Nat Rev. Cancer, 2014, 14 (3), 159-172.
-
(2014)
Nat Rev. Cancer
, vol.14
, Issue.3
, pp. 159-172
-
-
Stacker, S.A.1
Williams, S.P.2
Karnezis, T.3
Shayan, R.4
Fox, S.B.5
Achen, M.G.6
-
22
-
-
84857645999
-
Mirtron MicroRNA-1236 inhibits VEGFR-3 signaling during inflammatory lymphangiogenesis
-
Jones, D.; Li, Y.; He, Y.; Xu, Z.; Chen, H.; Min, W. Mirtron MicroRNA-1236 inhibits VEGFR-3 signaling during inflammatory lymphangiogenesis. Arterioscler. Thromb. Vasc. Biol., 2012, 32 (3), 633-642.
-
(2012)
Arterioscler. Thromb. Vasc. Biol
, vol.32
, Issue.3
, pp. 633-642
-
-
Jones, D.1
Li, Y.2
He, Y.3
Xu, Z.4
Chen, H.5
Min, W.6
-
23
-
-
78650383216
-
Functional analyses of the nonreceptor kinase bone marrow kinase on the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis
-
Jones, D.; Xu, Z.; Zhang, H.; He, Y.; Kluger, M.S.; Chen, H.; Min, W. Functional analyses of the nonreceptor kinase bone marrow kinase on the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis. Arterioscler. Thromb. Vasc. Biol., 2010, 30(12), 2553-2561.
-
(2010)
Arterioscler. Thromb. Vasc. Biol
, vol.30
, Issue.12
, pp. 2553-2561
-
-
Jones, D.1
Xu, Z.2
Zhang, H.3
He, Y.4
Kluger, M.S.5
Chen, H.6
Min, W.7
-
24
-
-
84894575189
-
AIP1 mediates vascular endothelial cell growth factor receptor-3-dependent angiogenic and lymphangiogenic responses
-
Zhou, H.J.; Chen, X.; Huang, Q.; Liu, R.; Zhang, H.; Wang, Y. Jin, Y.; Liang, X.; Lu, L.; Xu, Z.; Min, W. AIP1 mediates vascular endothelial cell growth factor receptor-3-dependent angiogenic and lymphangiogenic responses. Arterioscler. Thromb. Vasc. Biol., 2014, 34(3), 603-615.
-
(2014)
Arterioscler. Thromb. Vasc. Biol
, vol.34
, Issue.3
, pp. 603-615
-
-
Zhou, H.J.1
Chen, X.2
Huang, Q.3
Liu, R.4
Zhang, H.5
Wang, Y.6
Jin, Y.7
Liang, X.8
Lu, L.9
Xu, Z.10
Min, W.11
-
25
-
-
84902294371
-
Glutaredoxin 2 reduces both thioredoxin 2 and thioredoxin 1 and protects cells from apoptosis induced by auranofin and 4-Hydroxynonenal
-
[Epub ahead of print]
-
Zhang, H.; Du, Y.; Zhang, X.; Lu, J.; Holmgren, A. Glutaredoxin 2 reduces both thioredoxin 2 and thioredoxin 1 and protects cells from apoptosis induced by auranofin and 4-Hydroxynonenal. Antioxid. Redox. Signal, 2014. [Epub ahead of print].
-
(2014)
Antioxid. Redox. Signal
-
-
Zhang, H.1
Du, Y.2
Zhang, X.3
Lu, J.4
Holmgren, A.5
-
26
-
-
27144500188
-
The role of p38 MAPK activation in auranofin-induced apoptosis of human promyelocytic leukaemia HL-60 cells
-
Park, S.J.; Kim, I.S. The role of p38 MAPK activation in auranofin-induced apoptosis of human promyelocytic leukaemia HL-60 cells. Br. J. Pharmacol., 2005, 146(4), 506-513.
-
(2005)
Br. J. Pharmacol
, vol.146
, Issue.4
, pp. 506-513
-
-
Park, S.J.1
Kim, I.S.2
-
27
-
-
78751705649
-
The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-kappaB activity
-
Nakaya, A.; Sagawa, M.; Muto, A.; Uchida, H.; Ikeda, Y.; Kizaki, M. The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-kappaB activity. Leukemia Res., 2011, 35(2), 243-249.
-
(2011)
Leukemia Res
, vol.35
, Issue.2
, pp. 243-249
-
-
Nakaya, A.1
Sagawa, M.2
Muto, A.3
Uchida, H.4
Ikeda, Y.5
Kizaki, M.6
-
28
-
-
0035029131
-
Properties and biological activities of thioredoxins
-
Powis, G.; Montfort, W.R. Properties and biological activities of thioredoxins. Annu. Rev. Pharmacol.Toxicol., 2001, 41, 261-295.
-
(2001)
Annu. Rev. Pharmacol.Toxicol
, vol.41
, pp. 261-295
-
-
Powis, G.1
Montfort, W.R.2
-
29
-
-
84874051169
-
Thioredoxin and Thioredoxintarget proteins: From molecular mechanisms to functional significance
-
Lee, S.; Kim, S.M.; Lee, R.T. Thioredoxin and Thioredoxintarget proteins: From molecular mechanisms to functional significance. Antioxid. Redox. Signal., 2013, 18(10), 1165-207.
-
(2013)
Antioxid. Redox. Signal
, vol.18
, Issue.10
, pp. 1165-1207
-
-
Lee, S.1
Kim, S.M.2
Lee, R.T.3
-
30
-
-
84867711090
-
Thioredoxin system in cell death progression
-
Lu, J.; Holmgren, A. Thioredoxin system in cell death progression. Antioxid. Redox. Signal, 2012, 17(12), 1738-1747.
-
(2012)
Antioxid. Redox. Signal
, vol.17
, Issue.12
, pp. 1738-1747
-
-
Lu, J.1
Holmgren, A.2
-
31
-
-
0028091775
-
Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors
-
Pajusola, K.; Aprelikova, O.; Pelicci, G.; Weich, H.; Claesson-Welsh, L.; Alitalo, K. Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors. Oncogene, 1994, 9(12), 3545-3555.
-
(1994)
Oncogene
, vol.9
, Issue.12
, pp. 3545-3555
-
-
Pajusola, K.1
Aprelikova, O.2
Pelicci, G.3
Weich, H.4
Claesson-Welsh, L.5
Alitalo, K.6
-
32
-
-
3142677896
-
Immunodetection and quantification of vascular endothelial growth factor receptor-3 in human malignant tumor tissues
-
Bando, H.; Brokelmann, M.; Toi, M.; Alitalo, K.; Sleeman, J.P.; Sipos, B. Grone, H.J.; Weich, H.A. Immunodetection and quantification of vascular endothelial growth factor receptor-3 in human malignant tumor tissues. Int. J. Cancer, 2004, 111(2), 184-191.
-
(2004)
Int. J. Cancer
, vol.111
, Issue.2
, pp. 184-191
-
-
Bando, H.1
Brokelmann, M.2
Toi, M.3
Alitalo, K.4
Sleeman, J.P.5
Sipos, B.6
Grone, H.J.7
Weich, H.A.8
-
33
-
-
84890405966
-
Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity
-
Li, M.; Khambu, B.; Zhang, H.; Kang, J.H.; Chen, X.; Chen, D. Vollmer, L.; Liu, P.Q.; Vogt, A.; Yin, X.M. Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity. J. Biol. Chem., 2013, 288 (50), 35769-35780.
-
(2013)
J. Biol. Chem
, vol.288
, Issue.50
, pp. 35769-35780
-
-
Li, M.1
Khambu, B.2
Zhang, H.3
Kang, J.H.4
Chen, X.5
Chen, D.6
Vollmer, L.7
Liu, P.Q.8
Vogt, A.9
Yin, X.M.10
-
34
-
-
0033775891
-
Physiological functions of thioredoxin and thioredoxin reductase
-
Arner, E.S.; Holmgren, A. Physiological functions of thioredoxin and thioredoxin reductase. Eur. J.Biochem., 2000, 267(20), 6102-6109.
-
(2000)
Eur. J.Biochem
, vol.267
, Issue.20
, pp. 6102-6109
-
-
Arner, E.S.1
Holmgren, A.2
-
35
-
-
1642474377
-
Overexpression of thioredoxin reductase 1 regulates NF-kappa B activation
-
Sakurai, A.; Yuasa, K.; Shoji, Y.; Himeno, S.; Tsujimoto, M. Kunimoto, M.; Imura, N.; Hara, S. Overexpression of thioredoxin reductase 1 regulates NF-kappa B activation. J. Cell Physiol., 2004, 198 (1), 22-30.
-
(2004)
J. Cell Physiol
, vol.198
, Issue.1
, pp. 22-30
-
-
Sakurai, A.1
Yuasa, K.2
Shoji, Y.3
Himeno, S.4
Tsujimoto, M.5
Kunimoto, M.6
Imura, N.7
Hara, S.8
-
36
-
-
84887114785
-
Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems
-
Go, Y.M.; Roede, J.R.; Walker, D.I.; Duong, D.M.; Seyfried, N.T. Orr, M.; Liang, Y.; Pennell, K.D.; Jones, D.P. Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems. Mol. Cell Proteomics, 2013, 12(11), 3285-3296.
-
(2013)
Mol. Cell Proteomics
, vol.12
, Issue.11
, pp. 3285-3296
-
-
Go, Y.M.1
Roede, J.R.2
Walker, D.I.3
Duong, D.M.4
Seyfried, N.T.5
Orr, M.6
Liang, Y.7
Pennell, K.D.8
Jones, D.P.9
-
37
-
-
84877108416
-
Coordination of VEGF receptor trafficking and signaling by coreceptors
-
Nakayama, M.; Berger, P. Coordination of VEGF receptor trafficking and signaling by coreceptors. Exp. Cell Res., 2013, 319 (9), 1340-1307.
-
(2013)
Exp. Cell Res
, vol.319
, Issue.9
, pp. 1340-2307
-
-
Nakayama, M.1
Berger, P.2
-
38
-
-
84859453770
-
Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling
-
Benedito, R.; Rocha, S.F.; Woeste, M. Zamykal, M.; Radtke, F.; Casanovas, O.; Duarte, A.; Pytowski, B. Adams, R.H. Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Nature, 2012, 484(7392), 110-114.
-
(2012)
Nature
, vol.484
, Issue.7392
, pp. 110-114
-
-
Benedito, R.1
Rocha, S.F.2
Woeste, M.3
Zamykal, M.4
Radtke, F.5
Casanovas, O.6
Duarte, A.7
Pytowski, B.8
Adams, R.H.9
-
39
-
-
84874622432
-
Spatial regulation of VEGF receptor endocytosis in angiogenesis
-
Nakayama, M.; Nakayama, A.; Van Lessen, M.; Yamamoto, H.; Hoffmann, S.; Drexler, H.C.; Itoh, N. Hirose, T.; Breier, G.; Vestweber, D.; Cooper, J.A.; Ohno, S. Kaibuchi, K.; Adams, R.H. Spatial regulation of VEGF receptor endocytosis in angiogenesis. Nat. Cell, Biol., 2013, 15(3), 249-260.
-
(2013)
Nat. Cell, Biol
, vol.15
, Issue.3
, pp. 249-260
-
-
Nakayama, M.1
Nakayama, A.2
van Lessen, M.3
Yamamoto, H.4
Hoffmann, S.5
Drexler, H.C.6
Itoh, N.7
Hirose, T.8
Breier, G.9
Vestweber, D.10
Cooper, J.A.11
Ohno, S.12
Kaibuchi, K.13
Adams, R.H.14
|