Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-α-induced reactive oxygen species generation, NF-κB activation, and apoptosis

Toxicological Sciences

Volumn 91, Issue 2, 2006, Pages 643-650

  Hansen, Jason M ^a   Zhang, Hong ^a   Jones, Dean P ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; NF B; Oxidative damage; ROS generation; Thioredoxin; TNF

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MITOCHONDRIAL PROTEIN; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL COMPARTMENTALIZATION; CELL STIMULATION; CONTROLLED STUDY; CYTOTOXICITY; DETOXIFICATION; DOWNSTREAM PROCESSING; ENZYME ACTIVE SITE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NICK END LABELING; OXIDATION REDUCTION REACTION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; REPORTER GENE;

APOPTOSIS; HELA CELLS; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NF-KAPPA B; REACTIVE OXYGEN SPECIES; THIOREDOXIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33744809562     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj175     Document Type: Article

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