Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy

Cell Stress and Chaperones

Volumn 21, Issue 2, 2016, Pages 313-326

  Sane, Sanam ^a   Abdullah, Ammara ^a   Nelson, Morgan E ^a   Wang, Hongmin ^a   Chauhan, Subhash C ^b   Newton, Samuel S ^a   Rezvani, Khosrow ^a  

^a UNIVERSITY OF SOUTH DAKOTA   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Chemotherapy; Colon cancer; Mortalin; Osteosarcoma; p53; UBXN2A

Indexed keywords

CYCLOHEXIMIDE; FLUOROURACIL; HEAT SHOCK COGNATE PROTEIN 70; MORTALIN; POLYHISTIDINE TAG; PROTEIN P53; TUMOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UBXN2A PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; HEAT SHOCK PROTEIN 70; PROTEIN BINDING; UBIQUITIN; UBXN2A PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL MIGRATION; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DROSOPHILA MELANOGASTER; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; TREATMENT RESPONSE; U2OS CELL LINE; UPREGULATION; BINDING SITE; CHEMISTRY; COLONIC NEOPLASMS; DRUG EFFECTS; GENETICS; METABOLISM; MOLECULAR DOCKING; NEOPLASMS; OSTEOSARCOMA; PATHOLOGY; PROTEIN DOMAIN; RNA INTERFERENCE; TUMOR CELL LINE;

ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BINDING SITES; CELL LINE, TUMOR; COLONIC NEOPLASMS; FLUOROURACIL; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR DOCKING SIMULATION; NEOPLASMS; OSTEOSARCOMA; PROTEIN BINDING; PROTEIN DOMAINS; RNA INTERFERENCE; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS;

EID: 84961189949     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-015-0661-5     Document Type: Article

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