Functional significance of point mutations in stress chaperone mortalin and their relevance to parkinson disease

Journal of Biological Chemistry

Volumn 290, Issue 13, 2015, Pages 8447-8456

  Wadhwa, Renu ^a   Ryu, Jihoon ^a,b   Ahn, Hyo Min ^a,b   Saxena, Nishant ^a   Chaudhary, Anupama ^a   Yun, Chae Ok ^b   Kaul, Sunil C ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b Hanyang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE CONTROL; DISEASES;

APOPTOTIC FUNCTION; PARKINSON DISEASE; POINT MUTATIONS;

PATHOLOGY;

CHAPERONE; ELONGATION FACTOR 1ALPHA; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; MORTALIN; MOT 1 PROTEIN; MOT 2 PROTEIN; PROTEIN P53; RECOMBINANT PROTEIN; RIBOSOMAL PROTEIN L7; RIBOSOME PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; HEAT SHOCK PROTEIN 70; HSPA9 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL AGING; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NEUROPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; POINT MUTATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SCREENING TEST; ACTIVE TRANSPORT; CELL NUCLEUS; GENETICS; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; CARCINOGENESIS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MITOCHONDRIAL PROTEINS; MUTATION, MISSENSE; PARKINSON DISEASE; POINT MUTATION;

EID: 84925710322     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.627463     Document Type: Article

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