UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP

Biochemical Pharmacology

Volumn 97, Issue 4, 2015, Pages 518-530

  Teng, Yanfen ^a,d   Rezvani, Khosrow ^b   De Biasi, Mariella ^a,c  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH DAKOTA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d R and D   (China)

Author keywords

a3 Nicotinic subunit CHIP p97 UBXN2A UBX domain Proteasomal degradation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BETA2; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CARBOXYL TERMINUS HSP70 INTERACTING PROTEIN; COMPLEMENTARY DNA; HEAT SHOCK COGNATE PROTEIN 70; NICOTINIC RECEPTOR; PROTEASOME; PROTEIN; PROTEIN P97; SHORT HAIRPIN RNA; UBIQUITIN PROTEIN LIGASE E3; UBXN2A PROTEIN; UNCLASSIFIED DRUG; NUCLEAR PROTEIN; NUCLEAR PROTEIN IMPORT FACTOR P97; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CELL DIFFERENTIATION; CELL LYSATE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA LIBRARY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; UBIQUITINATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GOLGI COMPLEX; HEK293 CELL LINE; HUMAN; MALE; METABOLISM; MOUSE; NERVE CELL; PC12 CELL LINE; PHYSIOLOGY; TWO HYBRID SYSTEM;

ANIMALS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GOLGI APPARATUS; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; NEURONS; NUCLEAR PROTEINS; PC12 CELLS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RECEPTORS, NICOTINIC; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84943360948     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.08.084     Document Type: Article

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