-
1
-
-
0027414085
-
Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype
-
Wadhwa R., Kaul S.C., Ikawa Y., and Sugimoto Y. Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype J. Biol. Chem. 268 1993 6615 6621 (Pubitemid 23099365)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.9
, pp. 6615-6621
-
-
Wadhwa, R.1
Kaul, S.C.2
Ikawa, Y.3
Sugimoto, Y.4
-
2
-
-
0034682972
-
Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75
-
DOI 10.1006/bbrc.2000.3237
-
Ran Q., Wadhwa R., Kawai R., Kaul S.C., Sifers R.N., and Bick R.J. Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75 Biochem. Biophys. Res. Commun. 275 2000 174 179 (Pubitemid 30663648)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.275
, Issue.1
, pp. 174-179
-
-
Ran, Q.1
Wadhwa, R.2
Kawai, R.3
Kaul, S.C.4
Sifers, R.N.5
Bick, R.J.6
Smith, J.R.7
Pereira-Smith, O.M.8
-
3
-
-
34249741418
-
Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions
-
DOI 10.1196/annals.1395.032, Biogerontology: Mechanisms and Interventions
-
Yaguchi T., Aida S., Kaul S.C., and Wadhwa R. Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions Ann. N. Y. Acad. Sci. 1100 2007 306 311 (Pubitemid 47092666)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1100
, pp. 306-311
-
-
Yaguchi, T.1
Aida, S.2
Kaul, S.C.3
Wadhwa, R.4
-
4
-
-
33847651284
-
Three faces of mortalin: A housekeeper, guardian and killer
-
DOI 10.1016/j.exger.2006.10.020, PII S0531556506003342
-
Kaul S.C., Deocaris C.C., and Wadhwa R. Three faces of mortalin: a housekeeper, guardian and killer Exp. Gerontol. 42 2007 263 274 (Pubitemid 46356847)
-
(2007)
Experimental Gerontology
, vol.42
, Issue.4
, pp. 263-274
-
-
Kaul, S.C.1
Deocaris, C.C.2
Wadhwa, R.3
-
5
-
-
14244268253
-
Effect of GRP75/mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells
-
DOI 10.1007/s11010-005-2996-1
-
Liu Y., Liu W., Song X.D., and Zuo J. Effect of GRP75/mthsp70/PBP74/ mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells Mol. Cell. Biochem. 268 2005 45 51 (Pubitemid 40287825)
-
(2005)
Molecular and Cellular Biochemistry
, vol.268
, Issue.1-2
, pp. 45-51
-
-
Liu, Y.1
Liu, W.2
Song, X.-D.3
Zuo, J.4
-
6
-
-
0031443856
-
Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: A possible role in induced radioresistance
-
DOI 10.1080/095530097142807
-
Sadekova S., Lehnert S., and Chow T.Y. Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: a possible role in induced radioresistance Int. J. Radiat. Biol. 72 1997 653 660 (Pubitemid 28020329)
-
(1997)
International Journal of Radiation Biology
, vol.72
, Issue.6
, pp. 653-660
-
-
Sadekova, S.1
Lehnert, S.2
Chow, T.Y.-K.3
-
7
-
-
0037112550
-
i ratio in cultured vascular smooth muscle cells
-
DOI 10.1161/01.RES.0000043020.45534.3E
-
i ratio in cultured vascular smooth muscle cells Circ. Res. 91 2002 915 922 (Pubitemid 35373591)
-
(2002)
Circulation Research
, vol.91
, Issue.10
, pp. 915-922
-
-
Taurin, S.1
Seyrantepe, V.2
Orlov, S.N.3
Tremblay, T.-L.4
Thibault, P.5
Bennett, M.R.6
Hamet, P.7
Pshezhetsky, A.V.8
-
8
-
-
42449116100
-
Glucose-regulated protein 75 suppresses apoptosis induced by glucose deprivation in PC12 cells through inhibition of Bax conformational change
-
DOI 10.1111/j.1745-7270.2008.00409.x
-
Yang L., Liu X., Hao J., Yang Y., Zhao M., Zuo J., and Liu W. Glucose-regulated protein 75 suppresses apoptosis induced by glucose deprivation in PC12 cells through inhibition of Bax conformational change Acta Biochim. Biophys. Sin. (Shanghai) 40 2008 339 348 (Pubitemid 351572115)
-
(2008)
Acta Biochimica et Biophysica Sinica
, vol.40
, Issue.4
, pp. 339-348
-
-
Yang, L.1
Liu, X.2
Hao, J.3
Yang, Y.4
Zhao, M.5
Zuo, J.6
Liu, W.7
-
9
-
-
26444448463
-
The survival kinases Akt and Pim as potential pharmacological targets
-
DOI 10.1172/JCI26273
-
Amaravadi R., and Thompson C.B. The survival kinases Akt and Pim as potential pharmacological targets J. Clin. Invest. 115 2005 2618 2624 (Pubitemid 41434384)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2618-2624
-
-
Amaravadi, R.1
Thompson, C.B.2
-
10
-
-
11144253483
-
Convergent signal transduction pathways controlling cardiomyocyte survival and function: The role of PI 3-kinase and Akt
-
DOI 10.1016/j.yjmcc.2004.11.005, PII S0022282804003268
-
Matsui T., and Rosenzweig A. Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt J. Mol. Cell. Cardiol. 38 2005 63 71 (Pubitemid 40038652)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.38
, Issue.1
, pp. 63-71
-
-
Matsui, T.1
Rosenzweig, A.2
-
11
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
DOI 10.1038/sj.onc.1207102
-
Cory S., Huang D.C., and Adams J.M. The Bcl-2 family: roles in cell survival and oncogenesis Oncogene 22 2003 8590 8607 (Pubitemid 38028528)
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.S.2
Adams, J.M.3
-
12
-
-
0035936023
-
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
-
DOI 10.1038/sj/onc/1204984
-
Yamaguchi H., and Wang H.G. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change Oncogene 20 2001 7779 7786 (Pubitemid 33121951)
-
(2001)
Oncogene
, vol.20
, Issue.53
, pp. 7779-7786
-
-
Yamaguchi, H.1
Wang, H.-G.2
-
13
-
-
33847651284
-
Three faces of mortalin: A housekeeper, guardian and killer
-
DOI 10.1016/j.exger.2006.10.020, PII S0531556506003342
-
Kaul S.C., Deocaris C.C., and Wadhwa R. Three faces of mortalin: a housekeeper, guardian and killer Exp. Gerontol. 42 2007 263 274 (Pubitemid 46356847)
-
(2007)
Experimental Gerontology
, vol.42
, Issue.4
, pp. 263-274
-
-
Kaul, S.C.1
Deocaris, C.C.2
Wadhwa, R.3
-
14
-
-
33746265070
-
ERK and beyond: Insights from B-Raf and Raf-1 conditional knockouts
-
Galabova-Kovacs G., Kolbus A., Matzen D., Meissl K., Piazzolla D., and Rubiolo C. ERK and beyond: insights from B-Raf and Raf-1 conditional knockouts Cell Cycle 5 2006 1514 1518 (Pubitemid 44091970)
-
(2006)
Cell Cycle
, vol.5
, Issue.14
, pp. 1514-1518
-
-
Galabova-Kovacs, G.1
Kolbus, A.2
Matzen, D.3
Meissl, K.4
Piazzolla, D.5
Rubiolo, C.6
Steinitz, K.7
Baccarini, M.8
-
15
-
-
65949119310
-
How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
-
Mebratu Y., and Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: is subcellular localization the answer? Cell Cycle 8 2009 1168 1175
-
(2009)
Cell Cycle
, vol.8
, pp. 1168-1175
-
-
Mebratu, Y.1
Tesfaigzi, Y.2
-
16
-
-
0041344614
-
Heat shock protein 27 controls apoptosis by regulating Akt activation
-
DOI 10.1074/jbc.M303417200
-
Rane M.J., Pan Y., Singh S., Powell D.W., Wu R., and Cummins T. Heat shock protein 27 controls apoptosis by regulating Akt activation J. Biol. Chem. 278 2003 27828 27835 (Pubitemid 36899975)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.30
, pp. 27828-27835
-
-
Rane, M.J.1
Pan, Y.2
Singh, S.3
Powell, D.W.4
Wu, R.5
Cummins, T.6
Chen, Q.7
McLeish, K.R.8
Klein, J.B.9
-
17
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery
-
DOI 10.1016/S0092-8674(00)80405-5
-
Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., and Greenberg M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery Cell 91 1997 231 241 (Pubitemid 27456390)
-
(1997)
Cell
, vol.91
, Issue.2
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Xu, T.3
Masters, S.4
Haian, F.5
Gotoh, Y.6
Greenberg, M.E.7
-
18
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
DOI 10.1126/science.278.5338.687
-
L. del Peso, M. González-García, C. Page, R. Herrera, and G. Nuñez Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt Science 278 1997 687 689 (Pubitemid 27464966)
-
(1997)
Science
, vol.278
, Issue.5338
, pp. 687-689
-
-
Del Peso, L.1
Gonzalez-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
19
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
Song G., Ouyang G., and Bao S. The activation of Akt/PKB signaling pathway and cell survival J. Cell. Mol. Med. 9 2005 59 71
-
(2005)
J. Cell. Mol. Med.
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
20
-
-
33846514800
-
Proteomics exploration reveals that actin is a signaling target of the kinase Akt
-
DOI 10.1074/mcp.M600335-MCP200
-
Vandermoere F., El Yazidi-Belkoura I., Demont Y., Slomianny C., Antol J., Lemoine J., and Hondermarck H. Proteomics exploration reveals that actin is a signaling target of the kinase Akt Mol. Cell Proteomics 6 2007 114 124 (Pubitemid 46152696)
-
(2007)
Molecular and Cellular Proteomics
, vol.6
, Issue.1
, pp. 114-124
-
-
Vandermoere, F.1
El Yazidi-Belkoura, I.2
Demon, Y.3
Slomianny, C.4
Antol, J.5
Lemoine, J.6
Hondermarck, H.7
-
21
-
-
0028955637
-
Correlation between complementation group for immortality and the cellular distribution of mortalin
-
Wadhwa R., Pereira-Smith O.M., Reddel R.R., Sugimoto Y., Mitsui Y., and Kaul S.C. Correlation between complementation group for immortality and the cellular distribution of mortalin Exp. Cell Res. 216 1995 101 106
-
(1995)
Exp. Cell Res.
, vol.216
, pp. 101-106
-
-
Wadhwa, R.1
Pereira-Smith, O.M.2
Reddel, R.R.3
Sugimoto, Y.4
Mitsui, Y.5
Kaul, S.C.6
-
22
-
-
0034595925
-
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
-
Kaula S.C., Reddelb R.R., Sugiharac T., Mitsuia Y., and Wadhwac R. Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2 FEBS Lett. 474 2000 159 164
-
(2000)
FEBS Lett.
, vol.474
, pp. 159-164
-
-
Kaula, S.C.1
Reddelb, R.R.2
Sugiharac, T.3
Mitsuia, Y.4
Wadhwac, R.5
-
23
-
-
42549112997
-
Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro
-
DOI 10.1038/sj.jcbfm.9600600, PII 9600600
-
Voloboueva L.A., Duan M., Ouyang Y., Emery J.F., Stoy C., and Giffard R.G. Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro J. Cereb. Blood Flow Metab. 28 2008 1009 1016 (Pubitemid 351589637)
-
(2008)
Journal of Cerebral Blood Flow and Metabolism
, vol.28
, Issue.5
, pp. 1009-1016
-
-
Voloboueva, L.A.1
Duan, M.2
Ouyang, Y.3
Emery, J.F.4
Stoy, C.5
Giffard, R.G.6
-
24
-
-
2442681877
-
184 by Akt regulates its activity and apoptosis in neutrophils
-
DOI 10.1074/jbc.M400063200
-
Gardai S.J., Hildeman D.A., Frankel S.K., Whitlock B.B., Frasch S.C., and Borregaard N. Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils J. Biol. Chem. 279 2004 21085 21095 (Pubitemid 38656511)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.20
, pp. 21085-21095
-
-
Gardai, S.J.1
Hildeman, D.A.2
Frankel, S.K.3
Whitlock, B.B.4
Frasch, S.C.5
Borregaard, N.6
Marrack, P.7
Bratton, D.L.8
Henson, P.M.9
-
25
-
-
27144544082
-
Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis
-
DOI 10.1128/MCB.25.21.9369-9382.2005
-
Takahashi Y., Karbowski M., Yamaguchi H., Kazi A., Wu J., and Sebti S.M. Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis Mol. Cell. Biol. 25 2005 9369 9382 (Pubitemid 41507838)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.21
, pp. 9369-9382
-
-
Takahashi, Y.1
Karbowski, M.2
Yamaguchi, H.3
Kazi, A.4
Wu, J.5
Sebti, S.M.6
Youle, R.J.7
Wang, H.-G.8
-
26
-
-
0034605446
-
Role of the heat shock response and molecular chaperones in oncogenesis and cell death
-
Jolly C., and Morimoto R.I. Role of the heat shock response and molecular chaperones in oncogenesis and cell death J. Natl Cancer 92 2000 1564 1572
-
(2000)
J. Natl Cancer
, vol.92
, pp. 1564-1572
-
-
Jolly, C.1
Morimoto, R.I.2
-
27
-
-
17044387386
-
Hsp70 chaperones: Cellular functions and molecular mechanism
-
Mayer M.P., and Bukau B. Hsp70 chaperones: cellular functions and molecular mechanism Cell. Mol. Life Sci. 62 2005 670 684
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 670-684
-
-
Mayer, M.P.1
Bukau, B.2
-
28
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
Song G., Ouyang G., and Bao S. The activation of Akt/PKB signaling pathway and cell survival J. Cell. Mol. Med. 9 2005 59 71
-
(2005)
J. Cell. Mol. Med.
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
29
-
-
34249062137
-
Proteasome inhibitors induce a p38 mitogen-activated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer
-
Shi Y.Y., Small G.W., and Orlowski R.Z. Proteasome inhibitors induce a p38 mitogen-activated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer Breast Cancer Res. Treat. 100 2006 33 47
-
(2006)
Breast Cancer Res. Treat.
, vol.100
, pp. 33-47
-
-
Shi, Y.Y.1
Small, G.W.2
Orlowski, R.Z.3
-
30
-
-
0037163050
-
Regulation of Raf-Akt cross-talk
-
DOI 10.1074/jbc.M111974200
-
Moelling K., Schad K., Bosse M., Zimmermann S., and Schweneker M. Regulation of Raf-Akt cross-talk J. Biol. Chem. 277 2002 31099 31106 (Pubitemid 34970815)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.34
, pp. 31099-31106
-
-
Moelling, K.1
Schad, K.2
Bosse, M.3
Zimmermann, S.4
Schweneker, M.5
-
31
-
-
0035224494
-
Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells
-
McCubrey J.A., Lee J.T., Steelman L.S., Blalock W.L., Moye P.W., and Chang F. Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells Cancer Detect. Prev. 25 2001 375 393
-
(2001)
Cancer Detect. Prev.
, vol.25
, pp. 375-393
-
-
McCubrey, J.A.1
Lee, J.T.2
Steelman, L.S.3
Blalock, W.L.4
Moye, P.W.5
Chang, F.6
-
32
-
-
0033013866
-
Role of phosphoinositide 3-kinase in activation of Ras and mitogen- activated protein kinase by epidermal growth factor
-
Wennström S., and Downward J. Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor Mol. Cell. Biol. 19 1999 4279 4288 (Pubitemid 29242003)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.6
, pp. 4279-4288
-
-
Wennstrom, S.1
Downward, J.2
-
33
-
-
0027991899
-
Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase
-
Welsh G.I., Foulstone E.J., Young S.W., Tavaré J.M., and Proud C.G. Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase Biochem. J. 303 1994 15 20 (Pubitemid 24302892)
-
(1994)
Biochemical Journal
, vol.303
, Issue.1
, pp. 15-20
-
-
Welsh, G.I.1
Foulstone, E.J.2
Young, S.W.3
Tavare, J.M.4
Proud, C.G.5
-
34
-
-
0029943493
-
Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway
-
Hawes B.E., Luttrell L.M., van Biesen T., and Lefkowitz R.J. Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway J. Biol. Chem. 271 1996 12133 12136
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12133-12136
-
-
Hawes, B.E.1
Luttrell, L.M.2
Van Biesen, T.3
Lefkowitz, R.J.4
-
35
-
-
0030963602
-
Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
-
Hsu Y.T., Wolter K.G., and Youle R.J. Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis Proc. Natl Acad. Sci. USA 94 1997 3668 3672
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 3668-3672
-
-
Hsu, Y.T.1
Wolter, K.G.2
Youle, R.J.3
|