In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 43, 2012, Pages 17472-17477

  Zolov, Sergey N ^a   Bridges, Dave ^a   Zhang, Yanling ^a   Lee, Wei Wei ^a   Riehle, Ellen ^a   Verma, Rakesh ^a   Lenk, Guy M ^b   Converso Baran, Kimber ^b   Weide, Thomas ^c   Albin, Roger L ^b,d   Saltiel, Alan R ^a,b   Meisler, Miriam H ^b   Russell, Mark W ^b   Weisman, Lois S ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^d VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

Phosphoinositide; Spongiform

Indexed keywords

GLYCEROPHOSPHOLIPID; PHOSPHATIDYLINOSITOL 3,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; PIKFYVE PROTEIN; PROTEIN; PROTEIN PRECURSOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; GENE SILENCING; HEART DISEASE; KIDNEY DISEASE; LUNG DISEASE; MOUSE; NERVE DEGENERATION; NERVOUS TISSUE; NONHUMAN; PHENOTYPE; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; SPLEEN DISEASE; THYMUS DISEASE;

ANIMALS; CELLS, CULTURED; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, MUTANT STRAINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL PHOSPHATES; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84867908738     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1203106109     Document Type: Article

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