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Volumn 57, Issue 2, 2015, Pages 219-234

PI(5)P regulates autophagosome biogenesis

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 5; GLUCOSE; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 5 KINASE; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; PHOSPHATIDYLINOSITOL KINASE; UNCLASSIFIED DRUG; ATG16L1 PROTEIN, HUMAN; CARRIER PROTEIN; EGLN3 PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHATIDYLINOSITOL 5-PHOSPHATE; PIKFYVE PROTEIN, HUMAN; POLYPHOSPHOINOSITIDE;

EID: 84921615639     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.12.007     Document Type: Article
Times cited : (197)

References (60)
  • 1
    • 84864960430 scopus 로고    scopus 로고
    • Two-site recognition of phosphatidylinositol 3-phosphate by PROPPINs in autophagy
    • Baskaran S., Ragusa M.J., Boura E., Hurley J.H. Two-site recognition of phosphatidylinositol 3-phosphate by PROPPINs in autophagy. Mol. Cell 2012, 47:339-348.
    • (2012) Mol. Cell , vol.47 , pp. 339-348
    • Baskaran, S.1    Ragusa, M.J.2    Boura, E.3    Hurley, J.H.4
  • 2
    • 8044257699 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
    • Blommaart E.F., Krause U., Schellens J.P., Vreeling-Sindelárová H., Meijer A.J. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur. J. Biochem. 1997, 243:240-246.
    • (1997) Eur. J. Biochem. , vol.243 , pp. 240-246
    • Blommaart, E.F.1    Krause, U.2    Schellens, J.P.3    Vreeling-Sindelárová, H.4    Meijer, A.J.5
  • 3
    • 84880376355 scopus 로고    scopus 로고
    • Emerging regulation and functions of autophagy
    • Boya P., Reggiori F., Codogno P. Emerging regulation and functions of autophagy. Nat. Cell Biol. 2013, 15:713-720.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 713-720
    • Boya, P.1    Reggiori, F.2    Codogno, P.3
  • 4
    • 84881322547 scopus 로고    scopus 로고
    • Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage
    • Bua D.J., Martin G.M., Binda O., Gozani O. Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage. Sci. Rep. 2013, 3:2137.
    • (2013) Sci. Rep. , vol.3 , pp. 2137
    • Bua, D.J.1    Martin, G.M.2    Binda, O.3    Gozani, O.4
  • 5
    • 77955301963 scopus 로고    scopus 로고
    • Localization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinases
    • Clarke J.H., Wang M., Irvine R.F. Localization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinases. Adv. Enzyme Regul. 2010, 50:12-18.
    • (2010) Adv. Enzyme Regul. , vol.50 , pp. 12-18
    • Clarke, J.H.1    Wang, M.2    Irvine, R.F.3
  • 6
    • 84355162283 scopus 로고    scopus 로고
    • Canonical and non-canonical autophagy: variations on a common theme of self-eating?
    • Codogno P., Mehrpour M., Proikas-Cezanne T. Canonical and non-canonical autophagy: variations on a common theme of self-eating?. Nat. Rev. Mol. Cell Biol. 2012, 13:7-12.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 7-12
    • Codogno, P.1    Mehrpour, M.2    Proikas-Cezanne, T.3
  • 10
    • 84904575441 scopus 로고    scopus 로고
    • WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1
    • Dooley H.C., Razi M., Polson H.E., Girardin S.E., Wilson M.I., Tooze S.A. WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. Mol. Cell 2014, 55:238-252.
    • (2014) Mol. Cell , vol.55 , pp. 238-252
    • Dooley, H.C.1    Razi, M.2    Polson, H.E.3    Girardin, S.E.4    Wilson, M.I.5    Tooze, S.A.6
  • 11
    • 84879987829 scopus 로고    scopus 로고
    • AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve
    • Er E.E., Mendoza M.C., Mackey A.M., Rameh L.E., Blenis J. AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve. Sci. Signal. 2013, 6:ra45.
    • (2013) Sci. Signal. , vol.6 , pp. ra45
    • Er, E.E.1    Mendoza, M.C.2    Mackey, A.M.3    Rameh, L.E.4    Blenis, J.5
  • 13
    • 0035945343 scopus 로고    scopus 로고
    • Human VPS34 is required for internal vesicle formation within multivesicular endosomes
    • Futter C.E., Collinson L.M., Backer J.M., Hopkins C.R. Human VPS34 is required for internal vesicle formation within multivesicular endosomes. J.Cell Biol. 2001, 155:1251-1264.
    • (2001) J.Cell Biol. , vol.155 , pp. 1251-1264
    • Futter, C.E.1    Collinson, L.M.2    Backer, J.M.3    Hopkins, C.R.4
  • 17
    • 84857058225 scopus 로고    scopus 로고
    • Control of autophagy as a therapy for neurodegenerative disease
    • Harris H., Rubinsztein D.C. Control of autophagy as a therapy for neurodegenerative disease. Nat. Rev. Neurol. 2011, 8:108-117.
    • (2011) Nat. Rev. Neurol. , vol.8 , pp. 108-117
    • Harris, H.1    Rubinsztein, D.C.2
  • 19
    • 79953854419 scopus 로고    scopus 로고
    • The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice
    • Ikonomov O.C., Sbrissa D., Delvecchio K., Xie Y., Jin J.P., Rappolee D., Shisheva A. The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice. J.Biol. Chem. 2011, 286:13404-13413.
    • (2011) J.Biol. Chem. , vol.286 , pp. 13404-13413
    • Ikonomov, O.C.1    Sbrissa, D.2    Delvecchio, K.3    Xie, Y.4    Jin, J.P.5    Rappolee, D.6    Shisheva, A.7
  • 21
    • 2542450910 scopus 로고    scopus 로고
    • PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49
    • Jeffries T.R., Dove S.K., Michell R.H., Parker P.J. PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49. Mol. Biol. Cell 2004, 15:2652-2663.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2652-2663
    • Jeffries, T.R.1    Dove, S.K.2    Michell, R.H.3    Parker, P.J.4
  • 23
    • 84891368628 scopus 로고    scopus 로고
    • Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics
    • Li X., Wang X., Zhang X., Zhao M., Tsang W.L., Zhang Y., Yau R.G., Weisman L.S., Xu H. Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics. Proc. Natl. Acad. Sci. USA 2013, 110:21165-21170.
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 21165-21170
    • Li, X.1    Wang, X.2    Zhang, X.3    Zhao, M.4    Tsang, W.L.5    Zhang, Y.6    Yau, R.G.7    Weisman, L.S.8    Xu, H.9
  • 24
    • 84884742734 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle
    • Liu Y., Lai Y.C., Hill E.V., Tyteca D., Carpentier S., Ingvaldsen A., Vertommen D., Lantier L., Foretz M., Dequiedt F., et al. Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle. Biochem. J. 2013, 455:195-206.
    • (2013) Biochem. J. , vol.455 , pp. 195-206
    • Liu, Y.1    Lai, Y.C.2    Hill, E.V.3    Tyteca, D.4    Carpentier, S.5    Ingvaldsen, A.6    Vertommen, D.7    Lantier, L.8    Foretz, M.9    Dequiedt, F.10
  • 25
    • 82855170845 scopus 로고    scopus 로고
    • Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation
    • Mauthe M., Jacob A., Freiberger S., Hentschel K., Stierhof Y.D., Codogno P., Proikas-Cezanne T. Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation. Autophagy 2011, 7:1448-1461.
    • (2011) Autophagy , vol.7 , pp. 1448-1461
    • Mauthe, M.1    Jacob, A.2    Freiberger, S.3    Hentschel, K.4    Stierhof, Y.D.5    Codogno, P.6    Proikas-Cezanne, T.7
  • 26
    • 84877323647 scopus 로고    scopus 로고
    • Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2
    • McAlpine F., Williamson L.E., Tooze S.A., Chan E.Y. Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2. Autophagy 2013, 9:361-373.
    • (2013) Autophagy , vol.9 , pp. 361-373
    • McAlpine, F.1    Williamson, L.E.2    Tooze, S.A.3    Chan, E.Y.4
  • 27
    • 84859965801 scopus 로고    scopus 로고
    • Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D
    • Moreau K., Ravikumar B., Puri C., Rubinsztein D.C. Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D. J.Cell Biol. 2012, 196:483-496.
    • (2012) J.Cell Biol. , vol.196 , pp. 483-496
    • Moreau, K.1    Ravikumar, B.2    Puri, C.3    Rubinsztein, D.C.4
  • 30
    • 84882254367 scopus 로고    scopus 로고
    • The role of autophagy in neurodegenerative disease
    • Nixon R.A. The role of autophagy in neurodegenerative disease. Nat. Med. 2013, 19:983-997.
    • (2013) Nat. Med. , vol.19 , pp. 983-997
    • Nixon, R.A.1
  • 32
  • 33
    • 0033978633 scopus 로고    scopus 로고
    • Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
    • Petiot A., Ogier-Denis E., Blommaart E.F., Meijer A.J., Codogno P. Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J.Biol. Chem. 2000, 275:992-998.
    • (2000) J.Biol. Chem. , vol.275 , pp. 992-998
    • Petiot, A.1    Ogier-Denis, E.2    Blommaart, E.F.3    Meijer, A.J.4    Codogno, P.5
  • 34
    • 0141433284 scopus 로고    scopus 로고
    • PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
    • Petiot A., Faure J., Stenmark H., Gruenberg J. PI3P signaling regulates receptor sorting but not transport in the endosomal pathway. J.Cell Biol. 2003, 162:971-979.
    • (2003) J.Cell Biol. , vol.162 , pp. 971-979
    • Petiot, A.1    Faure, J.2    Stenmark, H.3    Gruenberg, J.4
  • 35
    • 39549117093 scopus 로고    scopus 로고
    • Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
    • Plowey E.D., Cherra S.J., Liu Y.J., Chu C.T. Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J.Neurochem. 2008, 105:1048-1056.
    • (2008) J.Neurochem. , vol.105 , pp. 1048-1056
    • Plowey, E.D.1    Cherra, S.J.2    Liu, Y.J.3    Chu, C.T.4
  • 36
    • 77953726483 scopus 로고    scopus 로고
    • Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
    • Polson H.E., de Lartigue J., Rigden D.J., Reedijk M., Urbé S., Clague M.J., Tooze S.A. Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagy 2010, 6:506-522.
    • (2010) Autophagy , vol.6 , pp. 506-522
    • Polson, H.E.1    de Lartigue, J.2    Rigden, D.J.3    Reedijk, M.4    Urbé, S.5    Clague, M.J.6    Tooze, S.A.7
  • 37
    • 0030721527 scopus 로고    scopus 로고
    • A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate
    • Rameh L.E., Tolias K.F., Duckworth B.C., Cantley L.C. A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. Nature 1997, 390:192-196.
    • (1997) Nature , vol.390 , pp. 192-196
    • Rameh, L.E.1    Tolias, K.F.2    Duckworth, B.C.3    Cantley, L.C.4
  • 38
    • 0036566266 scopus 로고    scopus 로고
    • Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
    • Ravikumar B., Duden R., Rubinsztein D.C. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum. Mol. Genet. 2002, 11:1107-1117.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1107-1117
    • Ravikumar, B.1    Duden, R.2    Rubinsztein, D.C.3
  • 39
    • 46249127490 scopus 로고    scopus 로고
    • Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
    • Ravikumar B., Imarisio S., Sarkar S., O'Kane C.J., Rubinsztein D.C. Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease. J.Cell Sci. 2008, 121:1649-1660.
    • (2008) J.Cell Sci. , vol.121 , pp. 1649-1660
    • Ravikumar, B.1    Imarisio, S.2    Sarkar, S.3    O'Kane, C.J.4    Rubinsztein, D.C.5
  • 40
    • 0035252980 scopus 로고    scopus 로고
    • Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation
    • Row P.E., Reaves B.J., Domin J., Luzio J.P., Davidson H.W. Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation. Biochem. J. 2001, 353:655-661.
    • (2001) Biochem. J. , vol.353 , pp. 655-661
    • Row, P.E.1    Reaves, B.J.2    Domin, J.3    Luzio, J.P.4    Davidson, H.W.5
  • 42
    • 77954930785 scopus 로고    scopus 로고
    • A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositides
    • Sarkes D., Rameh L.E. A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositides. Biochem. J. 2010, 428:375-384.
    • (2010) Biochem. J. , vol.428 , pp. 375-384
    • Sarkes, D.1    Rameh, L.E.2
  • 43
    • 0033618375 scopus 로고    scopus 로고
    • PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin
    • Sbrissa D., Ikonomov O.C., Shisheva A. PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin. J.Biol. Chem. 1999, 274:21589-21597.
    • (1999) J.Biol. Chem. , vol.274 , pp. 21589-21597
    • Sbrissa, D.1    Ikonomov, O.C.2    Shisheva, A.3
  • 44
    • 0037155216 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization
    • Sbrissa D., Ikonomov O.C., Shisheva A. Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization. J.Biol. Chem. 2002, 277:6073-6079.
    • (2002) J.Biol. Chem. , vol.277 , pp. 6073-6079
    • Sbrissa, D.1    Ikonomov, O.C.2    Shisheva, A.3
  • 45
    • 84865140750 scopus 로고    scopus 로고
    • Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636
    • Sbrissa D., Ikonomov O.C., Filios C., Delvecchio K., Shisheva A. Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636. Am. J. Physiol. Cell Physiol. 2012, 303:C436-C446.
    • (2012) Am. J. Physiol. Cell Physiol. , vol.303 , pp. C436-C446
    • Sbrissa, D.1    Ikonomov, O.C.2    Filios, C.3    Delvecchio, K.4    Shisheva, A.5
  • 46
    • 47249094223 scopus 로고    scopus 로고
    • Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
    • Scarlatti F., Maffei R., Beau I., Codogno P., Ghidoni R. Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ. 2008, 15:1318-1329.
    • (2008) Cell Death Differ. , vol.15 , pp. 1318-1329
    • Scarlatti, F.1    Maffei, R.2    Beau, I.3    Codogno, P.4    Ghidoni, R.5
  • 47
    • 84884724979 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
    • Schink K.O., Raiborg C., Stenmark H. Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling. BioEssays 2013, 35:900-912.
    • (2013) BioEssays , vol.35 , pp. 900-912
    • Schink, K.O.1    Raiborg, C.2    Stenmark, H.3
  • 48
    • 84885180114 scopus 로고    scopus 로고
    • PtdIns5P: news and views of its appearance, disappearance and deeds
    • Shisheva A. PtdIns5P: news and views of its appearance, disappearance and deeds. Arch. Biochem. Biophys. 2013, 538:171-180.
    • (2013) Arch. Biochem. Biophys. , vol.538 , pp. 171-180
    • Shisheva, A.1
  • 49
    • 0032517624 scopus 로고    scopus 로고
    • Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis
    • Siddhanta U., McIlroy J., Shah A., Zhang Y., Backer J.M. Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis. J.Cell Biol. 1998, 143:1647-1659.
    • (1998) J.Cell Biol. , vol.143 , pp. 1647-1659
    • Siddhanta, U.1    McIlroy, J.2    Shah, A.3    Zhang, Y.4    Backer, J.M.5
  • 52
    • 84893742000 scopus 로고    scopus 로고
    • Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics
    • Viaud J., Boal F., Tronchère H., Gaits-Iacovoni F., Payrastre B. Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics. Bioessays. 2014, 36:260-272.
    • (2014) Bioessays. , vol.36 , pp. 260-272
    • Viaud, J.1    Boal, F.2    Tronchère, H.3    Gaits-Iacovoni, F.4    Payrastre, B.5
  • 54
    • 0030944761 scopus 로고    scopus 로고
    • Phosphatidylinositol 3,5-bisphosphate defines a novel PI 3-kinase pathway in resting mouse fibroblasts
    • Whiteford C.C., Brearley C.A., Ulug E.T. Phosphatidylinositol 3,5-bisphosphate defines a novel PI 3-kinase pathway in resting mouse fibroblasts. Biochem. J. 1997, 323:597-601.
    • (1997) Biochem. J. , vol.323 , pp. 597-601
    • Whiteford, C.C.1    Brearley, C.A.2    Ulug, E.T.3
  • 55
    • 41449083237 scopus 로고    scopus 로고
    • Regulation of extranuclear PtdIns5P production by phosphatidylinositol phosphate 4-kinase 2alpha
    • Wilcox A., Hinchliffe K.A. Regulation of extranuclear PtdIns5P production by phosphatidylinositol phosphate 4-kinase 2alpha. FEBS Lett. 2008, 582:1391-1394.
    • (2008) FEBS Lett. , vol.582 , pp. 1391-1394
    • Wilcox, A.1    Hinchliffe, K.A.2
  • 57
    • 77952722628 scopus 로고    scopus 로고
    • Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway
    • Zhou X., Wang L., Hasegawa H., Amin P., Han B.X., Kaneko S., He Y., Wang F. Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway. Proc. Natl. Acad. Sci. USA 2010, 107:9424-9429.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 9424-9429
    • Zhou, X.1    Wang, L.2    Hasegawa, H.3    Amin, P.4    Han, B.X.5    Kaneko, S.6    He, Y.7    Wang, F.8
  • 58
    • 33847048316 scopus 로고    scopus 로고
    • Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
    • Zhu J.H., Horbinski C., Guo F., Watkins S., Uchiyama Y., Chu C.T. Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am. J. Pathol. 2007, 170:75-86.
    • (2007) Am. J. Pathol. , vol.170 , pp. 75-86
    • Zhu, J.H.1    Horbinski, C.2    Guo, F.3    Watkins, S.4    Uchiyama, Y.5    Chu, C.T.6
  • 60
    • 84862213105 scopus 로고    scopus 로고
    • Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8
    • Zou J., Zhang C., Marjanovic J., Kisseleva M.V., Majerus P.W., Wilson M.P. Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8. Proc. Natl. Acad. Sci. USA 2012, 109:9539-9544.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 9539-9544
    • Zou, J.1    Zhang, C.2    Marjanovic, J.3    Kisseleva, M.V.4    Majerus, P.W.5    Wilson, M.P.6


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