The dynein inhibitor Ciliobrevin D inhibits the bidirectional transport of organelles along sensory axons and impairs NGF-mediated regulation of growth cones and axon branches

Developmental Neurobiology

Volumn 75, Issue 7, 2015, Pages 757-777

  Sainath, Rajiv ^a   Gallo, Gianluca ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Axon branching; Axon growth; Axon transport; Ciliobrevin D; Dynein; Golgi derived vesicles; Kinesin; Latrunculin; Lysosome; Mitochondria; P150glued dynactin; Tubulin acetylation; Tubulin tyrosination; Wallerian degeneration

Indexed keywords

CILIOBREVIN D; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; ENZYME INHIBITOR; LATRUNCULIN A; NERVE GROWTH FACTOR; UNCLASSIFIED DRUG; FUSED HETEROCYCLIC RINGS; QUINAZOLINONE DERIVATIVE; THIAZOLIDINE DERIVATIVE;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ORGANELLE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; DEPOLYMERIZATION; ELECTROKYMOGRAPHY; EMBRYO; FILOPODIUM; GROWTH CONE; IN VITRO STUDY; LYSOSOME; MITOCHONDRION; NERVE FIBER; NERVE FIBER DEGENERATION; NERVE FIBER GROWTH; NERVE FIBER TRANSPORT; NONHUMAN; PRIORITY JOURNAL; SPINAL GANGLION; WALLERIAN DEGENERATION; ANIMAL; ANTAGONISTS AND INHIBITORS; AXON; CELL CULTURE; CHICK EMBRYO; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SENSORY NERVE CELL; TISSUE CULTURE TECHNIQUE; TRANSPORT AT THE CELLULAR LEVEL;

ACTIN CYTOSKELETON; ANIMALS; AXONS; BIOLOGICAL TRANSPORT; BRIDGED BICYCLO COMPOUNDS, HETEROCYCLIC; CELLS, CULTURED; CHICK EMBRYO; CYTOPLASM; DYNEINS; GANGLIA, SPINAL; GROWTH CONES; NERVE GROWTH FACTOR; ORGANELLES; QUINAZOLINONES; SENSORY RECEPTOR CELLS; THIAZOLIDINES; TISSUE CULTURE TECHNIQUES; WALLERIAN DEGENERATION;

EID: 84931022346     PISSN: 19328451     EISSN: 1932846X     Source Type: Journal    
DOI: 10.1002/dneu.22246     Document Type: Article

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