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Volumn 13, Issue 1, 2012, Pages 108-119

The enlarged lysosomes in beige j cells result from decreased lysosome fission and not increased lysosome fusion

Author keywords

Beige; Chediak Higashi syndrome fusion; Fission; Lysosome

Indexed keywords

CELL PROTEIN; PROTEIN CHS1; PROTEIN LYST; RINGER ACETATE; UNCLASSIFIED DRUG;

EID: 83255193923     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2011.01300.x     Document Type: Article
Times cited : (79)

References (68)
  • 2
    • 13944258097 scopus 로고    scopus 로고
    • Endocytic delivery to lysosomes mediated by concurrent fusion and kissing events in living cells
    • Bright NA, Gratian MJ, Luzio JP. Endocytic delivery to lysosomes mediated by concurrent fusion and kissing events in living cells. Curr Biol 2005;15:360-365.
    • (2005) Curr Biol , vol.15 , pp. 360-365
    • Bright, N.A.1    Gratian, M.J.2    Luzio, J.P.3
  • 3
    • 0025808286 scopus 로고
    • Maturation models for endosome and lysosome biogenesis
    • Murphy RF. Maturation models for endosome and lysosome biogenesis. Trends Cell Biol 1991;1:77-82.
    • (1991) Trends Cell Biol , vol.1 , pp. 77-82
    • Murphy, R.F.1
  • 4
    • 0030712859 scopus 로고    scopus 로고
    • Homotypic lysosome fusion in macrophages: analysis using an in vitro assay
    • Ward DM, Leslie JD, Kaplan J. Homotypic lysosome fusion in macrophages: analysis using an in vitro assay. J Cell Biol 1997;139:665-673.
    • (1997) J Cell Biol , vol.139 , pp. 665-673
    • Ward, D.M.1    Leslie, J.D.2    Kaplan, J.3
  • 5
    • 0032498539 scopus 로고    scopus 로고
    • Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent
    • Mullock BM, Bright NA, Fearon CW, Gray SR, Luzio JP. Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent. J Cell Biol 1998;140:591-601.
    • (1998) J Cell Biol , vol.140 , pp. 591-601
    • Mullock, B.M.1    Bright, N.A.2    Fearon, C.W.3    Gray, S.R.4    Luzio, J.P.5
  • 6
    • 0034729167 scopus 로고    scopus 로고
    • The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles
    • Pryor PR, Mullock BM, Bright NA, Gray SR, Luzio JP. The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles. J Cell Biol 2000;149:1053-1062.
    • (2000) J Cell Biol , vol.149 , pp. 1053-1062
    • Pryor, P.R.1    Mullock, B.M.2    Bright, N.A.3    Gray, S.R.4    Luzio, J.P.5
  • 7
    • 0033944546 scopus 로고    scopus 로고
    • Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages
    • Ward DM, Pevsner J, Scullion MA, Vaughn M, Kaplan J. Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Mol Biol Cell 2000;11:2327-2333.
    • (2000) Mol Biol Cell , vol.11 , pp. 2327-2333
    • Ward, D.M.1    Pevsner, J.2    Scullion, M.A.3    Vaughn, M.4    Kaplan, J.5
  • 8
    • 0037072602 scopus 로고    scopus 로고
    • A photoactivatable GFP for selective photolabeling of proteins and cells
    • Patterson GH, Lippincott-Schwartz J. A photoactivatable GFP for selective photolabeling of proteins and cells. Science 2002;297:1873-1877.
    • (2002) Science , vol.297 , pp. 1873-1877
    • Patterson, G.H.1    Lippincott-Schwartz, J.2
  • 14
    • 0032729471 scopus 로고    scopus 로고
    • Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome
    • Introne W, Boissy RE, Gahl WA. Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome. Mol Genet Metab 1999;68:283-303.
    • (1999) Mol Genet Metab , vol.68 , pp. 283-303
    • Introne, W.1    Boissy, R.E.2    Gahl, W.A.3
  • 15
    • 0035989918 scopus 로고    scopus 로고
    • Chediak-Higashi syndrome: a rare disorder of lysosomes and lysosome related organelles
    • Shiflett SL, Kaplan J, Ward DM. Chediak-Higashi syndrome: a rare disorder of lysosomes and lysosome related organelles. Pigment Cell Res 2002;15:251-257.
    • (2002) Pigment Cell Res , vol.15 , pp. 251-257
    • Shiflett, S.L.1    Kaplan, J.2    Ward, D.M.3
  • 16
    • 0035990979 scopus 로고    scopus 로고
    • Chediak-Higashi syndrome: a clinical and molecular view of a rare lysosomal storage disorder
    • Ward DM, Shiflett SL, Kaplan J. Chediak-Higashi syndrome: a clinical and molecular view of a rare lysosomal storage disorder. Curr Mol Med 2002;2:469-477.
    • (2002) Curr Mol Med , vol.2 , pp. 469-477
    • Ward, D.M.1    Shiflett, S.L.2    Kaplan, J.3
  • 20
    • 0038782826 scopus 로고    scopus 로고
    • The role of BEACH proteins in Dictyostelium
    • De Lozanne A. The role of BEACH proteins in Dictyostelium. Traffic 2003;4:6-12.
    • (2003) Traffic , vol.4 , pp. 6-12
    • De Lozanne, A.1
  • 21
    • 2442720280 scopus 로고    scopus 로고
    • Structure-function analysis of the BEACH protein LvsA
    • Wu WI, Yajnik J, Siano M, De Lozanne A. Structure-function analysis of the BEACH protein LvsA. Traffic 2004;5:346-355.
    • (2004) Traffic , vol.5 , pp. 346-355
    • Wu, W.I.1    Yajnik, J.2    Siano, M.3    De Lozanne, A.4
  • 22
    • 33746287754 scopus 로고    scopus 로고
    • The contractile vacuole in Ca2+-regulation in Dictyostelium: its essential function for cAMP-induced Ca2+-influx
    • Malchow D, Lusche DF, Schlatterer C, De Lozanne A, Muller-Taubenberger A. The contractile vacuole in Ca2+-regulation in Dictyostelium: its essential function for cAMP-induced Ca2+-influx. BMC Dev Biol 2006;6:31.
    • (2006) BMC Dev Biol , vol.6 , pp. 31
    • Malchow, D.1    Lusche, D.F.2    Schlatterer, C.3    De Lozanne, A.4    Muller-Taubenberger, A.5
  • 24
    • 70450214965 scopus 로고    scopus 로고
    • Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses
    • Medrihan L, Rohlmann A, Fairless R, Andrae J, Doring M, Missler M, Zhang W, Kilimann MW. Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses. J Physiol 2009;587:5095-5106.
    • (2009) J Physiol , vol.587 , pp. 5095-5106
    • Medrihan, L.1    Rohlmann, A.2    Fairless, R.3    Andrae, J.4    Doring, M.5    Missler, M.6    Zhang, W.7    Kilimann, M.W.8
  • 25
    • 4444262622 scopus 로고    scopus 로고
    • Bph1p, the Saccharomyces cerevisiae homologue of CHS1/beige, functions in cell wall formation and protein sorting
    • Shiflett SL, Vaughn MB, Huynh D, Kaplan J, Ward DM. Bph1p, the Saccharomyces cerevisiae homologue of CHS1/beige, functions in cell wall formation and protein sorting. Traffic 2004;5:700-710.
    • (2004) Traffic , vol.5 , pp. 700-710
    • Shiflett, S.L.1    Vaughn, M.B.2    Huynh, D.3    Kaplan, J.4    Ward, D.M.5
  • 26
    • 0030693642 scopus 로고    scopus 로고
    • The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein
    • Perou CM, Leslie JD, Green W, Li L, Ward DM, Kaplan J. The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein. J Biol Chem 1997;272:29790-29794.
    • (1997) J Biol Chem , vol.272 , pp. 29790-29794
    • Perou, C.M.1    Leslie, J.D.2    Green, W.3    Li, L.4    Ward, D.M.5    Kaplan, J.6
  • 27
    • 0027746217 scopus 로고
    • Complementation analysis of Chediak-Higashi syndrome: the same gene may be responsible for the defect in all patients and species
    • Perou CM, Kaplan J. Complementation analysis of Chediak-Higashi syndrome: the same gene may be responsible for the defect in all patients and species. Somat Cell Mol Genet 1993;19:459-468.
    • (1993) Somat Cell Mol Genet , vol.19 , pp. 459-468
    • Perou, C.M.1    Kaplan, J.2
  • 28
    • 0036178067 scopus 로고    scopus 로고
    • Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome
    • Harris E, Wang N, Wu Wl WL, Weatherford A, De Lozanne A, Cardelli J. Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome. Mol Biol Cell 2002;13:656-669.
    • (2002) Mol Biol Cell , vol.13 , pp. 656-669
    • Harris, E.1    Wang, N.2    Wu Wl, W.L.3    Weatherford, A.4    De Lozanne, A.5    Cardelli, J.6
  • 29
    • 34249029018 scopus 로고    scopus 로고
    • The BEACH protein LvsB is localized on lysosomes and postlysosomes and limits their fusion with early endosomes
    • Kypri E, Schmauch C, Maniak M, De Lozanne A. The BEACH protein LvsB is localized on lysosomes and postlysosomes and limits their fusion with early endosomes. Traffic 2007;8:774-783.
    • (2007) Traffic , vol.8 , pp. 774-783
    • Kypri, E.1    Schmauch, C.2    Maniak, M.3    De Lozanne, A.4
  • 30
    • 34547764415 scopus 로고    scopus 로고
    • A LYST/beige homolog is involved in biogenesis of Dictyostelium secretory lysosomes
    • Charette SJ, Cosson P. A LYST/beige homolog is involved in biogenesis of Dictyostelium secretory lysosomes. J Cell Sci 2007;120:2338-2343.
    • (2007) J Cell Sci , vol.120 , pp. 2338-2343
    • Charette, S.J.1    Cosson, P.2
  • 31
    • 0027435586 scopus 로고
    • Chediak-Higashi syndrome is not due to a defect in microtubule-based lysosomal mobility
    • Perou CM, Kaplan J. Chediak-Higashi syndrome is not due to a defect in microtubule-based lysosomal mobility. J Cell Sci 1993;106:99-107.
    • (1993) J Cell Sci , vol.106 , pp. 99-107
    • Perou, C.M.1    Kaplan, J.2
  • 32
    • 0024523485 scopus 로고
    • Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH
    • Heuser J. Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH. J Cell Biol 1989;108:855-864.
    • (1989) J Cell Biol , vol.108 , pp. 855-864
    • Heuser, J.1
  • 34
    • 30944441523 scopus 로고    scopus 로고
    • The small chemical vacuolin-1 alters the morphology of lysosomes without inhibiting Ca2+-regulated exocytosis
    • Huynh C, Andrews NW. The small chemical vacuolin-1 alters the morphology of lysosomes without inhibiting Ca2+-regulated exocytosis. EMBO Rep 2005;6:843-847.
    • (2005) EMBO Rep , vol.6 , pp. 843-847
    • Huynh, C.1    Andrews, N.W.2
  • 35
    • 0346018912 scopus 로고
    • Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules
    • Swanson J, Bushnell A, Silverstein SC. Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules. Proc Natl Acad Sci U S A 1987;84:1921-1925.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 1921-1925
    • Swanson, J.1    Bushnell, A.2    Silverstein, S.C.3
  • 36
    • 0025045429 scopus 로고
    • Radial extension of macrophage tubular lysosomes supported by kinesin
    • Hollenbeck PJ, Swanson JA. Radial extension of macrophage tubular lysosomes supported by kinesin. Nature 1990;346:864-866.
    • (1990) Nature , vol.346 , pp. 864-866
    • Hollenbeck, P.J.1    Swanson, J.A.2
  • 38
    • 69249135065 scopus 로고    scopus 로고
    • Tickets to ride: selecting cargo for clathrin-regulated internalization
    • Traub LM. Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol 2009;10:583-596.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 583-596
    • Traub, L.M.1
  • 39
    • 77954957013 scopus 로고    scopus 로고
    • Membrane budding and scission by the ESCRT machinery: it's all in the neck
    • Hurley JH, Hanson PI. Membrane budding and scission by the ESCRT machinery: it's all in the neck. Nat Rev Mol Cell Biol 2010;11:556-566.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 556-566
    • Hurley, J.H.1    Hanson, P.I.2
  • 40
    • 77949532806 scopus 로고    scopus 로고
    • New insights into the structural mechanisms of the COPII coat
    • Russell C, Stagg SM. New insights into the structural mechanisms of the COPII coat. Traffic 2010;11:303-310.
    • (2010) Traffic , vol.11 , pp. 303-310
    • Russell, C.1    Stagg, S.M.2
  • 41
    • 46049089793 scopus 로고    scopus 로고
    • Coordination of COPII vesicle trafficking by Sec23
    • Fromme JC, Orci L, Schekman R. Coordination of COPII vesicle trafficking by Sec23. Trends Cell Biol 2008;18:330-336.
    • (2008) Trends Cell Biol , vol.18 , pp. 330-336
    • Fromme, J.C.1    Orci, L.2    Schekman, R.3
  • 42
    • 69949183624 scopus 로고    scopus 로고
    • Conserved functions of membrane active GTPases in coated vesicle formation
    • Pucadyil TJ, Schmid SL. Conserved functions of membrane active GTPases in coated vesicle formation. Science 2009;325:1217-1220.
    • (2009) Science , vol.325 , pp. 1217-1220
    • Pucadyil, T.J.1    Schmid, S.L.2
  • 43
    • 78650168518 scopus 로고    scopus 로고
    • Physical aspects of COPI vesicle formation
    • Pinot M, Goud B, Manneville JB. Physical aspects of COPI vesicle formation. Mol Membr Biol 2010;8:428-442.
    • (2010) Mol Membr Biol , vol.8 , pp. 428-442
    • Pinot, M.1    Goud, B.2    Manneville, J.B.3
  • 45
    • 36549023194 scopus 로고    scopus 로고
    • Maintaining peroxisome populations: a story of division and inheritance
    • Fagarasanu A, Fagarasanu M, Rachubinski RA. Maintaining peroxisome populations: a story of division and inheritance. Annu Rev Cell Dev Biol 2007;23:321-344.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 321-344
    • Fagarasanu, A.1    Fagarasanu, M.2    Rachubinski, R.A.3
  • 46
    • 33645754484 scopus 로고    scopus 로고
    • Organelles on the move: insights from yeast vacuole inheritance
    • Weisman LS. Organelles on the move: insights from yeast vacuole inheritance. Nat Rev Mol Cell Biol 2006;7:243-252.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 243-252
    • Weisman, L.S.1
  • 47
    • 3343021872 scopus 로고    scopus 로고
    • Microtubule-dependent movement of late endocytic vesicles in vitro: requirements for Dynein and Kinesin
    • Bananis E, Nath S, Gordon K, Satir P, Stockert RJ, Murray JW, Wolkoff AW. Microtubule-dependent movement of late endocytic vesicles in vitro: requirements for Dynein and Kinesin. Mol Biol Cell 2004;15:3688-3697.
    • (2004) Mol Biol Cell , vol.15 , pp. 3688-3697
    • Bananis, E.1    Nath, S.2    Gordon, K.3    Satir, P.4    Stockert, R.J.5    Murray, J.W.6    Wolkoff, A.W.7
  • 48
    • 79951835447 scopus 로고    scopus 로고
    • Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes
    • Caviston JP, Zajac AL, Tokito M, Holzbaur EL. Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes. Mol Biol Cell 2011;22:478-492.
    • (2011) Mol Biol Cell , vol.22 , pp. 478-492
    • Caviston, J.P.1    Zajac, A.L.2    Tokito, M.3    Holzbaur, E.L.4
  • 50
    • 70350620810 scopus 로고    scopus 로고
    • The dynamin-related protein Vps1 regulates vacuole fission, fusion and tubulation in the fission yeast, Schizosaccharomyces pombe
    • Rothlisberger S, Jourdain I, Johnson C, Takegawa K, Hyams JS. The dynamin-related protein Vps1 regulates vacuole fission, fusion and tubulation in the fission yeast, Schizosaccharomyces pombe. Fungal Genet Biol 2009;46:927-935.
    • (2009) Fungal Genet Biol , vol.46 , pp. 927-935
    • Rothlisberger, S.1    Jourdain, I.2    Johnson, C.3    Takegawa, K.4    Hyams, J.S.5
  • 51
    • 77956409167 scopus 로고    scopus 로고
    • Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system
    • Wu M, Huang B, Graham M, Raimondi A, Heuser JE, Zhuang X, De Camilli P. Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system. Nat Cell Biol 2010;12:902-908.
    • (2010) Nat Cell Biol , vol.12 , pp. 902-908
    • Wu, M.1    Huang, B.2    Graham, M.3    Raimondi, A.4    Heuser, J.E.5    Zhuang, X.6    De Camilli, P.7
  • 52
    • 0037119998 scopus 로고    scopus 로고
    • Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain
    • Jogl G, Shen Y, Gebauer D, Li J, Wiegmann K, Kashkar H, Kronke M, Tong L. Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain. EMBO J 2002;21:4785-4795.
    • (2002) EMBO J , vol.21 , pp. 4785-4795
    • Jogl, G.1    Shen, Y.2    Gebauer, D.3    Li, J.4    Wiegmann, K.5    Kashkar, H.6    Kronke, M.7    Tong, L.8
  • 53
  • 54
    • 0034548872 scopus 로고    scopus 로고
    • Neurobeachin: a protein kinase A-anchoring, beige/Chediak-Higashi protein homolog implicated in neuronal membrane traffic
    • Wang X, Herberg FW, Laue MM, Wullner C, Hu B, Petrasch-Parwez E, Kilimann MW. Neurobeachin: a protein kinase A-anchoring, beige/Chediak-Higashi protein homolog implicated in neuronal membrane traffic. J Neurosci 2000;20:8551-8565.
    • (2000) J Neurosci , vol.20 , pp. 8551-8565
    • Wang, X.1    Herberg, F.W.2    Laue, M.M.3    Wullner, C.4    Hu, B.5    Petrasch-Parwez, E.6    Kilimann, M.W.7
  • 55
    • 0034881566 scopus 로고    scopus 로고
    • A thiol proteinase inhibitor, E-64-d, corrects the abnormalities in concanavalin A cap formation and the lysosomal enzyme activity in leucocytes from patients with Chediak-Higashi syndrome by reversing the down-regulated protein kinase C activity
    • Cui SH, Tanabe F, Terunuma H, Iwatani Y, Nunoi H, Agematsu K, Komiyama A, Nomura A, Hara T, Onodera T, Iwata T, Ito M. A thiol proteinase inhibitor, E-64-d, corrects the abnormalities in concanavalin A cap formation and the lysosomal enzyme activity in leucocytes from patients with Chediak-Higashi syndrome by reversing the down-regulated protein kinase C activity. Clin Exp Immunol 2001;125:283-290.
    • (2001) Clin Exp Immunol , vol.125 , pp. 283-290
    • Cui, S.H.1    Tanabe, F.2    Terunuma, H.3    Iwatani, Y.4    Nunoi, H.5    Agematsu, K.6    Komiyama, A.7    Nomura, A.8    Hara, T.9    Onodera, T.10    Iwata, T.11    Ito, M.12
  • 56
    • 0024380506 scopus 로고
    • The thiol proteinase inhibitors improve the abnormal rapid down-regulation of protein kinase C and the impaired natural killer cell activity in (Chediak-Higashi syndrome) beige mouse
    • Ito M, Sato A, Tanabe F, Ishida E, Takami Y, Shigeta S. The thiol proteinase inhibitors improve the abnormal rapid down-regulation of protein kinase C and the impaired natural killer cell activity in (Chediak-Higashi syndrome) beige mouse. Biochem Biophys Res Commun 1989;160:433-440.
    • (1989) Biochem Biophys Res Commun , vol.160 , pp. 433-440
    • Ito, M.1    Sato, A.2    Tanabe, F.3    Ishida, E.4    Takami, Y.5    Shigeta, S.6
  • 57
    • 0023918402 scopus 로고
    • Rapid down-regulation of protein kinase C in (Chediak-Higashi syndrome) beige mouse by phorbol ester
    • Ito M, Tanabe F, Takami Y, Sato A, Shigeta S. Rapid down-regulation of protein kinase C in (Chediak-Higashi syndrome) beige mouse by phorbol ester. Biochem Biophys Res Commun 1988;153:648-656.
    • (1988) Biochem Biophys Res Commun , vol.153 , pp. 648-656
    • Ito, M.1    Tanabe, F.2    Takami, Y.3    Sato, A.4    Shigeta, S.5
  • 58
    • 0033844501 scopus 로고    scopus 로고
    • Abnormal down-regulation of PKC is responsible for giant granule formation in fibroblasts from CHS (beige) mice--a thiol proteinase inhibitor, E-64-d, prevents giant granule formation in beige fibroblasts
    • Tanabe F, Cui SH, Ito M. Abnormal down-regulation of PKC is responsible for giant granule formation in fibroblasts from CHS (beige) mice--a thiol proteinase inhibitor, E-64-d, prevents giant granule formation in beige fibroblasts. J Leukoc Biol 2000;67:749-755.
    • (2000) J Leukoc Biol , vol.67 , pp. 749-755
    • Tanabe, F.1    Cui, S.H.2    Ito, M.3
  • 59
    • 11844296738 scopus 로고    scopus 로고
    • Rapid biogenesis and sensitization of secretory lysosomes in NK cells mediated by target-cell recognition
    • Liu D, Xu L, Yang F, Li D, Gong F, Xu T. Rapid biogenesis and sensitization of secretory lysosomes in NK cells mediated by target-cell recognition. Proc Natl Acad Sci U S A 2005;102:123-127.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 123-127
    • Liu, D.1    Xu, L.2    Yang, F.3    Li, D.4    Gong, F.5    Xu, T.6
  • 60
    • 58149300245 scopus 로고    scopus 로고
    • Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity
    • Ma JS, Haydar TF, Radoja S. Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity. J Immunol 2008;181:4716-4722.
    • (2008) J Immunol , vol.181 , pp. 4716-4722
    • Ma, J.S.1    Haydar, T.F.2    Radoja, S.3
  • 61
    • 0027093271 scopus 로고
    • In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae
    • Conradt B, Shaw J, Vida T, Emr S, Wickner W. In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 1992;119:1469-1479.
    • (1992) J Cell Biol , vol.119 , pp. 1469-1479
    • Conradt, B.1    Shaw, J.2    Vida, T.3    Emr, S.4    Wickner, W.5
  • 62
    • 0034689024 scopus 로고    scopus 로고
    • The docking stage of yeast vacuole fusion requires the transfer of proteins from a cis-SNARE complex to a Rab/Ypt protein
    • Price A, Seals D, Wickner W, Ungermann C. The docking stage of yeast vacuole fusion requires the transfer of proteins from a cis-SNARE complex to a Rab/Ypt protein. J Cell Biol 2000;148:1231-1238.
    • (2000) J Cell Biol , vol.148 , pp. 1231-1238
    • Price, A.1    Seals, D.2    Wickner, W.3    Ungermann, C.4
  • 64
    • 0033790619 scopus 로고    scopus 로고
    • Yeast homotypic vacuole fusion: a window on organelle trafficking mechanisms
    • Wickner W, Haas A. Yeast homotypic vacuole fusion: a window on organelle trafficking mechanisms. Annu Rev Biochem 2000;69:247-275.
    • (2000) Annu Rev Biochem , vol.69 , pp. 247-275
    • Wickner, W.1    Haas, A.2
  • 66
    • 0034004206 scopus 로고    scopus 로고
    • Reconstitution of ATP-dependent movement of endocytic vesicles along microtubules in vitro: an oscillatory bidirectional process
    • Murray JW, Bananis E, Wolkoff AW. Reconstitution of ATP-dependent movement of endocytic vesicles along microtubules in vitro: an oscillatory bidirectional process. Mol Biol Cell 2000;11:419-433.
    • (2000) Mol Biol Cell , vol.11 , pp. 419-433
    • Murray, J.W.1    Bananis, E.2    Wolkoff, A.W.3
  • 67
    • 41849085244 scopus 로고    scopus 로고
    • Single vesicle analysis of endocytic fission on microtubules in vitro
    • Murray JW, Sarkar S, Wolkoff AW. Single vesicle analysis of endocytic fission on microtubules in vitro. Traffic 2008;9:833-847.
    • (2008) Traffic , vol.9 , pp. 833-847
    • Murray, J.W.1    Sarkar, S.2    Wolkoff, A.W.3
  • 68
    • 33745757459 scopus 로고    scopus 로고
    • PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter
    • Sarkar S, Bananis E, Nath S, Anwer MS, Wolkoff AW, Murray JW. PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter. Traffic 2006;7:1078-1091.
    • (2006) Traffic , vol.7 , pp. 1078-1091
    • Sarkar, S.1    Bananis, E.2    Nath, S.3    Anwer, M.S.4    Wolkoff, A.W.5    Murray, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.