Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Park, Dohyun ^a   Jeong, Heeyoon ^a   Lee, Mi Nam ^a   Koh, Ara ^a   Kwon, Ohman ^a   Yang, Yong Ryoul ^b   Noh, Jungeun ^a   Suh, Pann Ghill ^b   Park, Hwangseo ^c   Ryu, Sung Ho ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Ulsan National Institute of Science and Technology   (South Korea)

^c Sejong University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; LUCIFERASE; MTOR PROTEIN, HUMAN; PROTEIN BINDING; RESVERATROL; SERINE THREONINE PROTEIN KINASE ULK1; SIGNAL PEPTIDE; STILBENE DERIVATIVE; TARGET OF RAPAMYCIN KINASE; ULK1 PROTEIN, HUMAN;

ANTAGONISTS AND INHIBITORS; AUTOPHAGY; BINDING COMPETITION; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; MCF-7 CELL LINE; METABOLISM; MOLECULAR DOCKING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; REPORTER GENE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN-1 HOMOLOG; BINDING, COMPETITIVE; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HEK293 CELLS; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MCF-7 CELLS; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN DOMAINS; PROTEIN STRUCTURE, SECONDARY; SIGNAL TRANSDUCTION; STILBENES; TOR SERINE-THREONINE KINASES;

EID: 84959419408     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21772     Document Type: Article

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