When your cap matters: Structural insights into self vs non-self recognition of 5' RNA by immunomodulatory host proteins

Current Opinion in Structural Biology

Volumn 36, Issue , 2016, Pages 133-141

  Leung, Daisy W ^a   Amarasinghe, Gaya K ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; DOUBLE STRANDED RNA; INTERFERON INDUCED PROTEINS WITH TETRATRICOPEPTIDE REPEAT PROTEIN; MELANOMA DIFFERENTIATION ASSOCIATED FACTOR GENE 5; PATHOGEN ASSOCIATED MOLECULAR PATTERN; RETINOIC ACID INDUCIBLE PROTEIN I; RNA; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; VIRUS RNA; CAPPED RNA; CARRIER PROTEIN; PROTEIN BINDING; RNA BINDING PROTEIN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; METHYLATION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; REVIEW; RNA STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VIRUS DETECTION; ANIMAL; CHEMISTRY; CONFORMATION; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION;

ANIMALS; CARRIER PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RNA; RNA CAPS; RNA, VIRAL; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84959324048     PISSN: 0959440X     EISSN: 1879033X     Source Type: Journal    
DOI: 10.1016/j.sbi.2016.02.001     Document Type: Review

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