The thermodynamic basis for viral RNA detection by the RIG-I innate immune sensor

Journal of Biological Chemistry

Volumn 287, Issue 51, 2012, Pages 42564-42573

  Vela, Adriana ^a   Fedorova, Olga ^a,b   Ding, Steve C ^c   Pyle, Anna Marie ^a,b  

^a YALE UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; COVALENT LINKAGE; INNATE IMMUNE RESPONSE; RNA LIGAND; RNA STRUCTURES; THERMO DYNAMIC ANALYSIS; VIRAL RNA;

BINDING ENERGY; LIGANDS; PROTEINS; THERMOANALYSIS; VIRUSES;

RNA;

DOUBLE STRANDED RNA; RETINOIC ACID INDUCIBLE PROTEIN I; VIRUS RNA;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; COVALENT BOND; CRYSTALLOGRAPHY; INNATE IMMUNITY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN ISOLATION; RNA ANALYSIS; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

HUMANS; IMMUNITY, INNATE; KINETICS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA, DOUBLE-STRANDED; RNA, VIRAL; SUBSTRATE SPECIFICITY; THERMODYNAMICS; UBIQUITIN-PROTEIN LIGASES;

VERTEBRATA;

EID: 84869765600     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.385146     Document Type: Article

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