Cellular and molecular modifier pathways in tauopathies: The big picture from screening invertebrate models

Journal of Neurochemistry

Volumn 137, Issue 1, 2016, Pages 12-25

  Hannan, Shabab B ^a,b   Dräger, Nina M ^a   Rasse, Tobias M ^a   Voigt, Aaron ^c   Jahn, Thomas R ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

C. elegans; Drosophila; genome wide association studies; modifier screen; neurodegeneration; Tau

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN; TAU PROTEIN; HYBRID PROTEIN; MAPT PROTEIN, HUMAN;

APOPTOSIS; CAENORHABDITIS ELEGANS; CELL CYCLE REGULATION; CYTOSKELETON; DROSOPHILA; GENE FUNCTION; GENETIC TRANSCRIPTION; MAPT GENE; MOLECULAR DYNAMICS; MUTANT; NERVE FIBER TRANSPORT; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; REGULATORY MECHANISM; REVIEW; RNA METABOLISM; TAUOPATHY; WILD TYPE; ANIMAL; CELL CYCLE; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INVERTEBRATE; KNOCKOUT MOUSE; LONGEVITY; METABOLISM; MOUSE; MUTATION; NERVE DEGENERATION; PROTEIN PROCESSING; TRANSGENIC ANIMAL; ULTRASTRUCTURE; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; AXONAL TRANSPORT; CAENORHABDITIS ELEGANS; CELL CYCLE; CYTOSKELETON; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HUMANS; INVERTEBRATES; LONGEVITY; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, KNOCKOUT; MUTATION; NERVE DEGENERATION; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT FUSION PROTEINS; TAU PROTEINS; TAUOPATHIES; ZEBRAFISH;

EID: 84958260342     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13532     Document Type: Review

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