Essential role of POLDIP2 in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition

Biochemical and Biophysical Research Communications

Volumn 462, Issue 2, 2015, Pages 112-118

  Kim, YoungDoo ^a   Park, Hyejin ^a   Nah, Jihoon ^a   Moon, Seowon ^a   Lee, WonJae ^a   Hong, Se Hoon ^a   Kam, Tae In ^a   Jung, Yong Keun ^a  

^a Seoul National University   (South Korea)

Author keywords

Autophagy; Lifespan; POLDIP2; Proteasome; Tau

Indexed keywords

PEPTIDES AND PROTEINS; POLYMERASE DELTA INTERACTING PROTEIN 2; TAU PROTEIN; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; MAPT PROTEIN, HUMAN; NUCLEAR PROTEIN; POLDIP2 PROTEIN, HUMAN; PROTEASOME; REACTIVE OXYGEN METABOLITE; RECOMBINANT PROTEIN; SMALL INTERFERING RNA;

ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOWN REGULATION; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENE; GENE SILENCING; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; METABOLISM; NERVE DEGENERATION; PATHOLOGY; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; AUTOPHAGY; CELL LINE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE KNOCKDOWN TECHNIQUES; GENES, INSECT; HEK293 CELLS; HELA CELLS; HUMANS; NERVE DEGENERATION; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TAU PROTEINS;

EID: 84929838913     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.04.084     Document Type: Article

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