메뉴 건너뛰기




Volumn 12, Issue 1, 2000, Pages 63-71

Functional cooperation between the microtubule and actin cytoskeletons

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; KHELLIN; METHENAMINE; PROTEIN;

EID: 0033953888     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(99)00058-7     Document Type: Review
Times cited : (428)

References (46)
  • 1
    • 0031011532 scopus 로고    scopus 로고
    • Microtubule-microfilament synergy in the cytoskeleton
    • Edited by Jeon, K.W. Academic, Press Inc: San Diego, London
    • Gavin, R.H. Microtubule-microfilament synergy in the cytoskeleton. In International Review of Cytology. Edited by Jeon, K.W. Academic, Press Inc: San Diego, London; 1997, 173:207-242.
    • (1997) In International Review of Cytology , vol.173 , pp. 207-242
    • Gavin, R.H.1
  • 2
    • 0033520387 scopus 로고    scopus 로고
    • Crossroads on cytokeletal highways
    • Fuchs E., Yang Y. Crossroads on cytokeletal highways. Cell. 98:1999;547-550.
    • (1999) Cell , vol.98 , pp. 547-550
    • Fuchs, E.1    Yang, Y.2
  • 3
    • 0000701757 scopus 로고    scopus 로고
    • Weaving a tangled web: The interconnected cytoskeleton
    • Klymkowsky M.W. Weaving a tangled web: the interconnected cytoskeleton. Nat Cell Biol. 1:1999;E121-E123.
    • (1999) Nat Cell Biol , vol.1
    • Klymkowsky, M.W.1
  • 4
    • 0026534466 scopus 로고
    • Actin-dependent organelle movement in squid axoplasm
    • Kuznetsov S.A., Langford G.M., Weiss D.G. Actin-dependent organelle movement in squid axoplasm. Nature. 356:1992;722-725.
    • (1992) Nature , vol.356 , pp. 722-725
    • Kuznetsov, S.A.1    Langford, G.M.2    Weiss, D.G.3
  • 5
    • 0028942256 scopus 로고
    • Actin- And microtubule-dependent organelle motors: Interrelationships between the two motility systems
    • Langford G.M. Actin- and microtubule-dependent organelle motors: interrelationships between the two motility systems. Curr Opin Cell Biol. 7:1995;82-88.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 82-88
    • Langford, G.M.1
  • 7
    • 0032576766 scopus 로고    scopus 로고
    • Functional coordination of microtubule-based and actin-based motility in melanophores
    • Reveals that pigment granules in melanophores are transported on actin filaments in addition to MTs. Actin filaments are required for uniform dispersal of the granules in the cytoplasm. Suggests that granule transport occurs through coordinated MT- and actin-based transport
    • Rodionov V.I., Hope A.J., Svitkina T.M., Borisy G.G. Functional coordination of microtubule-based and actin-based motility in melanophores. Curr Biol. 8:1998;165-168. Reveals that pigment granules in melanophores are transported on actin filaments in addition to MTs. Actin filaments are required for uniform dispersal of the granules in the cytoplasm. Suggests that granule transport occurs through coordinated MT- and actin-based transport.
    • (1998) Curr Biol , vol.8 , pp. 165-168
    • Rodionov, V.I.1    Hope, A.J.2    Svitkina, T.M.3    Borisy, G.G.4
  • 8
    • 0032576778 scopus 로고    scopus 로고
    • Myosin cooperates with microtubule motors during organelle transport in melanophores
    • •]. It demonstrates that granules can move on both actin filaments and MTs in vitro and that an unconventional myosin is associated with the granules, which may drive actin-based transport. This is a promising system to dissect the molecular mechanisms underlying the dual-based transport
    • •]. It demonstrates that granules can move on both actin filaments and MTs in vitro and that an unconventional myosin is associated with the granules, which may drive actin-based transport. This is a promising system to dissect the molecular mechanisms underlying the dual-based transport.
    • (1998) Curr Biol , vol.8 , pp. 161-164
    • Rogers, S.L.1    Gelfand, V.I.2
  • 9
    • 0033590558 scopus 로고    scopus 로고
    • Direct interaction of microtubule- And actin-based transport motors
    • The first demonstration of a direct association between a MT motor and an unconventional myosin. Raises the possibility that similar 'hetero-motor' complexes may be widely utilized for coordinated MT- and actin-based transport of vesicles and organelles
    • Huang J-D., Brady S.T., Richards B.W., Stenoien D., Resau J.H., Copeland N.G., Jenkins N.A. Direct interaction of microtubule- and actin-based transport motors. Nature. 397:1999;267-270. The first demonstration of a direct association between a MT motor and an unconventional myosin. Raises the possibility that similar 'hetero-motor' complexes may be widely utilized for coordinated MT- and actin-based transport of vesicles and organelles.
    • (1999) Nature , vol.397 , pp. 267-270
    • Huang, J.-D.1    Brady, S.T.2    Richards, B.W.3    Stenoien, D.4    Resau, J.H.5    Copeland, N.G.6    Jenkins, N.A.7
  • 10
    • 0030861056 scopus 로고    scopus 로고
    • Dimerization of the highly conserved light chain shared by dynein and myosin V
    • Benashski S.E., Harrison A., Patel-King R.S., King S.M. Dimerization of the highly conserved light chain shared by dynein and myosin V. J Biol Chem. 272:1997;20929-20935.
    • (1997) J Biol Chem , vol.272 , pp. 20929-20935
    • Benashski, S.E.1    Harrison, A.2    Patel-King, R.S.3    King, S.M.4
  • 11
    • 0030071321 scopus 로고    scopus 로고
    • Cleavage plane specification in C. elegans: How to divide the spoils
    • White J., Strome S. Cleavage plane specification in C. elegans: how to divide the spoils. Cell. 84:1996;195-198.
    • (1996) Cell , vol.84 , pp. 195-198
    • White, J.1    Strome, S.2
  • 12
    • 0023020417 scopus 로고
    • Establishment of the mechanism of cytokinesis in animal cells
    • Rappaport R. Establishment of the mechanism of cytokinesis in animal cells. Int Rev Cyt. 105:1986;245-281.
    • (1986) Int Rev Cyt , vol.105 , pp. 245-281
    • Rappaport, R.1
  • 13
    • 0030958087 scopus 로고    scopus 로고
    • Cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin
    • Chang F., Drubin D., Nurse P. Cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J Cell Biol. 137:1997;169-182.
    • (1997) J Cell Biol , vol.137 , pp. 169-182
    • Chang, F.1    Drubin, D.2    Nurse, P.3
  • 14
    • 0031194074 scopus 로고    scopus 로고
    • Actin cytoskeleton: Are FH proteins local organizers?
    • Frazier J.A., Field C.M. Actin cytoskeleton: are FH proteins local organizers? Curr Biol. 7:1997;414-417.
    • (1997) Curr Biol , vol.7 , pp. 414-417
    • Frazier, J.A.1    Field, C.M.2
  • 15
    • 0033615081 scopus 로고    scopus 로고
    • Movement of a cytokinesis factor Cdcl2p to the site of cell division
    • Shows that Cdc12p, a spatial cue for cytokinesis in fission yeast, is part of a large 65S complex, and that GFP-Cdc12p is transported as a 'spot' along both actin cables and MT tracks in vivo prior to being deposited at the cell cortex. MT-actin interactions have been hypothesized to be involved in placement of the cleavage plane in animal cells but this is the first demonstration of such interactions
    • Chang F. Movement of a cytokinesis factor Cdcl2p to the site of cell division. Curr Biol. 9:1999;849-852. Shows that Cdc12p, a spatial cue for cytokinesis in fission yeast, is part of a large 65S complex, and that GFP-Cdc12p is transported as a 'spot' along both actin cables and MT tracks in vivo prior to being deposited at the cell cortex. MT-actin interactions have been hypothesized to be involved in placement of the cleavage plane in animal cells but this is the first demonstration of such interactions.
    • (1999) Curr Biol , vol.9 , pp. 849-852
    • Chang, F.1
  • 16
    • 0030271941 scopus 로고    scopus 로고
    • Cortical domains and the mechanisms of asymmetric cell division
    • Gonczy P., Hyman A.A. Cortical domains and the mechanisms of asymmetric cell division. Trends Cell Biol. 6:1996;382-387.
    • (1996) Trends Cell Biol , vol.6 , pp. 382-387
    • Gonczy, P.1    Hyman, A.A.2
  • 17
    • 0032497694 scopus 로고    scopus 로고
    • The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos
    • Shows that the dynactin complex localizes to the cortical actin site where astral MT ends interact during spindle rotation in C. elegans embryos. Further, dynactin is required for proper spindle rotation
    • Skop A.R., White J.G. The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos. Curr Biol. 8:1998;R1110-R1116. Shows that the dynactin complex localizes to the cortical actin site where astral MT ends interact during spindle rotation in C. elegans embryos. Further, dynactin is required for proper spindle rotation.
    • (1998) Curr Biol , vol.8
    • Skop, A.R.1    White, J.G.2
  • 18
    • 0033004145 scopus 로고    scopus 로고
    • Cytoplasmic dynein and dynactin in cell division and intracellular transport
    • Karki S., Holzbaur E.L.F. Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr Opin Cell Biol. 11:1999;45-53.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 45-53
    • Karki, S.1    Holzbaur, E.L.F.2
  • 19
    • 0030750203 scopus 로고    scopus 로고
    • Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex
    • Carminati J.L., Stearns T. Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex. J Cell Biol. 138:1997;629-641.
    • (1997) J Cell Biol , vol.138 , pp. 629-641
    • Carminati, J.L.1    Stearns, T.2
  • 20
    • 0030668938 scopus 로고    scopus 로고
    • Astral microtubule dynamics in yeast: A microtubule-based searching mechanism for spindle orientation and nuclear migration into the bud
    • Shaw S.L., Yeh E., Maddox P., Salmon E.D., Bloom K. Astral microtubule dynamics in yeast: a microtubule-based searching mechanism for spindle orientation and nuclear migration into the bud. J Cell Biol. 139:1997;985-994.
    • (1997) J Cell Biol , vol.139 , pp. 985-994
    • Shaw, S.L.1    Yeh, E.2    Maddox, P.3    Salmon, E.D.4    Bloom, K.5
  • 21
    • 0033535340 scopus 로고    scopus 로고
    • Microtubule dynamics from mating through the first zygotic division in the budding yeast Saccharomyces cerevisiae
    • The first reported characterization of MT dynamics in living yeast cells during the mating response. It reveals that astral MTs become anchored at the mating projection tip cell cortex. This study is the first to demonstrate that cortically captured MTs shorten from their captured plus ends, rather than their minus ends associated with the spindle pole body (microtubule organizing center)
    • Addox P., Chin E., Mallavarapu A., Yeh E., Salmon E.D., Bloom K. Microtubule dynamics from mating through the first zygotic division in the budding yeast Saccharomyces cerevisiae. J Cell Biol. 144:1999;977-987. The first reported characterization of MT dynamics in living yeast cells during the mating response. It reveals that astral MTs become anchored at the mating projection tip cell cortex. This study is the first to demonstrate that cortically captured MTs shorten from their captured plus ends, rather than their minus ends associated with the spindle pole body (microtubule organizing center).
    • (1999) J Cell Biol , vol.144 , pp. 977-987
    • Addox, P.1    Chin, E.2    Mallavarapu, A.3    Yeh, E.4    Salmon, E.D.5    Bloom, K.6
  • 22
    • 0030720491 scopus 로고    scopus 로고
    • The cell center at 100 ('Centrosomes and Spindle Pole Bodies', ASCB-EMBO-H. Dudley Wright Conference, 1997)
    • Stearns T., Winey M. The cell center at 100 ('Centrosomes and Spindle Pole Bodies', ASCB-EMBO-H. Dudley Wright Conference, 1997). Cell. 91:1997;303-309.
    • (1997) Cell , vol.91 , pp. 303-309
    • Stearns, T.1    Winey, M.2
  • 23
    • 0026781163 scopus 로고
    • Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae
    • Palmer R.E., Sullivan D.S., Huffaker T., Koshland D. Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae. J Cell Biol. 119:1992;583-593.
    • (1992) J Cell Biol , vol.119 , pp. 583-593
    • Palmer, R.E.1    Sullivan, D.S.2    Huffaker, T.3    Koshland, D.4
  • 24
    • 0027090325 scopus 로고
    • Actin- And tubulin-dependent functions during Saccharomyces cerevisiae mating projection formation
    • Read E.B., Okamura H.H., Drubin D.G. Actin- and tubulin-dependent functions during Saccharomyces cerevisiae mating projection formation. Mol Biol Cell. 3:1992;429-444.
    • (1992) Mol Biol Cell , vol.3 , pp. 429-444
    • Read, E.B.1    Okamura, H.H.2    Drubin, D.G.3
  • 25
    • 0032567757 scopus 로고    scopus 로고
    • Kar9p is a novel cortical protein required for cytoplasmic microtubule orientation in yeast
    • Identifies Kar9p as a factor involved in guiding MT ends to the cell cortex during both mitosis and mating response in budding yeast. Kar9p is involved in an earlier step of nuclear migration than dynein, and loss of Kar9p and dynein functions in combination is lethal
    • Miller R.K., Rose M.D. Kar9p is a novel cortical protein required for cytoplasmic microtubule orientation in yeast. J Cell Biol. 140:1998;377-390. Identifies Kar9p as a factor involved in guiding MT ends to the cell cortex during both mitosis and mating response in budding yeast. Kar9p is involved in an earlier step of nuclear migration than dynein, and loss of Kar9p and dynein functions in combination is lethal.
    • (1998) J Cell Biol , vol.140 , pp. 377-390
    • Miller, R.K.1    Rose, M.D.2
  • 26
    • 0033535321 scopus 로고    scopus 로고
    • The cortical localization of the microtubule orientation protein, Kar9p, is dependent upon actin and proteins required for polarization
    • GFP-Kar9p localization at bud tips and at mating projection tips is dependent both on actin and on several factors required for establishing cell polarity. Disruption of the actin cytoskeleton with latrunculin A leads to translocation of Kar9p from the cell tips to the astral MTs and SPBs. This is the first indication that Kar9p or associated factors can bind to MTs
    • Miller R.K., Matheos D., Rose M.D. The cortical localization of the microtubule orientation protein, Kar9p, is dependent upon actin and proteins required for polarization. J Cell Biol. 144:1999;963-975. GFP-Kar9p localization at bud tips and at mating projection tips is dependent both on actin and on several factors required for establishing cell polarity. Disruption of the actin cytoskeleton with latrunculin A leads to translocation of Kar9p from the cell tips to the astral MTs and SPBs. This is the first indication that Kar9p or associated factors can bind to MTs.
    • (1999) J Cell Biol , vol.144 , pp. 963-975
    • Miller, R.K.1    Matheos, D.2    Rose, M.D.3
  • 27
    • 0033535351 scopus 로고    scopus 로고
    • Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p
    • The authors show that actin and Bni1p are both required for proper spindle orientation and positioning in budding yeast. This study also provides evidence that spindle orientation requires an actin structure that is involved in bud-site selection and that polarization of cortical actin patches is not required
    • Lee L., Klee S.K., Evangelista M., Boone C., Pellman D. Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p. J Cell Biol. 144:1999;947-961. The authors show that actin and Bni1p are both required for proper spindle orientation and positioning in budding yeast. This study also provides evidence that spindle orientation requires an actin structure that is involved in bud-site selection and that polarization of cortical actin patches is not required.
    • (1999) J Cell Biol , vol.144 , pp. 947-961
    • Lee, L.1    Klee, S.K.2    Evangelista, M.3    Boone, C.4    Pellman, D.5
  • 28
    • 0032858387 scopus 로고    scopus 로고
    • The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle
    • A careful study demonstrating that actin cables but not patches are required for maintaining spindle orientation. Suggests that actin cables are required either for the delivery of components of the MT capture site at the bud tip or that they might serve as tracks for transporting MT ends to the bud cortex
    • Theesfeld C.L., Irazoqui J.E., Bloom K., Lew D.J. The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle. J Cell Biol. 146:1999;1019-1031. A careful study demonstrating that actin cables but not patches are required for maintaining spindle orientation. Suggests that actin cables are required either for the delivery of components of the MT capture site at the bud tip or that they might serve as tracks for transporting MT ends to the bud cortex.
    • (1999) J Cell Biol , vol.146 , pp. 1019-1031
    • Theesfeld, C.L.1    Irazoqui, J.E.2    Bloom, K.3    Lew, D.J.4
  • 29
    • 0032514208 scopus 로고    scopus 로고
    • Targeting, capture, and stabilization of microtubules at early focal adhesions
    • MT dynamic behavior was observed in living migrating fibroblasts using GFP-tubulin to label MTs and GFP-vinculin to label cortical focal points. MTs were targeted to and transiently captured at focal points, leading to the model that MT ends may be transported on actin cables emanating from the actin foci
    • Kaverina I., Rottner K., Small J.V. Targeting, capture, and stabilization of microtubules at early focal adhesions. J Cell Biol. 142:1998;181-190. MT dynamic behavior was observed in living migrating fibroblasts using GFP-tubulin to label MTs and GFP-vinculin to label cortical focal points. MTs were targeted to and transiently captured at focal points, leading to the model that MT ends may be transported on actin cables emanating from the actin foci.
    • (1998) J Cell Biol , vol.142 , pp. 181-190
    • Kaverina, I.1    Rottner, K.2    Small, J.V.3
  • 30
    • 0030884059 scopus 로고    scopus 로고
    • Motoring in the finish: Kinesin and dynein work together to orient the yeast mitotic spindle
    • Stearns T. Motoring in the finish: kinesin and dynein work together to orient the yeast mitotic spindle. J Cell Biol. 138:1997;957-960.
    • (1997) J Cell Biol , vol.138 , pp. 957-960
    • Stearns, T.1
  • 31
    • 0033535324 scopus 로고    scopus 로고
    • Formin' the connection between microtubules and the cell cortex
    • Heil-Chapdelaine R.A., Adames N.R., Cooper J.A. Formin' the connection between microtubules and the cell cortex. J Cell Biol. 144:1999;809-811.
    • (1999) J Cell Biol , vol.144 , pp. 809-811
    • Heil-Chapdelaine, R.A.1    Adames, N.R.2    Cooper, J.A.3
  • 32
    • 0033198781 scopus 로고    scopus 로고
    • The coronin family of actin-associated proteins
    • de Hostos E.L. The coronin family of actin-associated proteins. Trends Cell Biol. 9:1999;345-350.
    • (1999) Trends Cell Biol , vol.9 , pp. 345-350
    • De Hostos, E.L.1
  • 33
    • 0033545203 scopus 로고    scopus 로고
    • Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast
    • Actin and Crn1p were co-isolated from yeast extracts on a MT affinity column. Crn1p is a homologue of the ubiquitous actin-associated protein coronin. Purified Crn1p was demonstrated to directly link MTs and actin filaments in vitro
    • Goode B.L., Wong J.J., Butty A-C., Peter M., McCormack A.L., Yates J.R., Drubin D.G., Barnes G. Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast. J Cell Biol. 144:1999;83-98. Actin and Crn1p were co-isolated from yeast extracts on a MT affinity column. Crn1p is a homologue of the ubiquitous actin-associated protein coronin. Purified Crn1p was demonstrated to directly link MTs and actin filaments in vitro.
    • (1999) J Cell Biol , vol.144 , pp. 83-98
    • Goode, B.L.1    Wong, J.J.2    Butty, A.-C.3    Peter, M.4    McCormack, A.L.5    Yates, J.R.6    Drubin, D.G.7    Barnes, G.8
  • 34
    • 0032547996 scopus 로고    scopus 로고
    • The role of Saccharomcyes cerevisiae coronin in the actin and microtubule cytoskeletons
    • Heil-Chapdelaine R.A., Tran N.K., Cooper J.A. The role of Saccharomcyes cerevisiae coronin in the actin and microtubule cytoskeletons. Curr Biol. 8:1998;1281-1284.
    • (1998) Curr Biol , vol.8 , pp. 1281-1284
    • Heil-Chapdelaine, R.A.1    Tran, N.K.2    Cooper, J.A.3
  • 35
    • 0032966238 scopus 로고    scopus 로고
    • Positive feedback interactions between microtubule and actin dynamics during cell motility
    • Waterman-Storer C.M., Salmon E.D. Positive feedback interactions between microtubule and actin dynamics during cell motility. Curr Opin Cell Biol. 11:1999;61-67.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 61-67
    • Waterman-Storer, C.M.1    Salmon, E.D.2
  • 36
    • 0033128163 scopus 로고    scopus 로고
    • A method for movement
    • Zigmond S.H. A method for movement. Nat Cell Biol. 1:1999;E12.
    • (1999) Nat Cell Biol , vol.1 , pp. 12
    • Zigmond, S.H.1
  • 37
    • 0032559641 scopus 로고    scopus 로고
    • A class VI unconventional myosin is associated with a homologue of a microtubule-binding protein, cytoplasmic linker protein-170, in neurons and at the posterior pole of Drosophila embryos
    • The authors demonstrate association between an unconventional myosin in Drosophila and a novel protein DCLIP190, a homologue of CLIP170. As CLIP170 is associated with the growing ends of MTs in other organisms, this suggests that a CLIP190-myosin complex could link MT ends to actin cables
    • Lantz V.A., Miller K.G. A class VI unconventional myosin is associated with a homologue of a microtubule-binding protein, cytoplasmic linker protein-170, in neurons and at the posterior pole of Drosophila embryos. J Cell Biol. 140:1998;897-910. The authors demonstrate association between an unconventional myosin in Drosophila and a novel protein DCLIP190, a homologue of CLIP170. As CLIP170 is associated with the growing ends of MTs in other organisms, this suggests that a CLIP190-myosin complex could link MT ends to actin cables.
    • (1998) J Cell Biol , vol.140 , pp. 897-910
    • Lantz, V.A.1    Miller, K.G.2
  • 38
    • 0033582659 scopus 로고    scopus 로고
    • CLIP-170 highlights growing microtubule ends in vivo
    • CLIP170 is thought to be an adapter for linking endocytic vesicles to MTs. In this study, GFP-CLIP170 is shown to associate with the growing ends of MTs in vivo
    • Perez F., Diamantopoulos G.S., Stalder R., Kreis T.E. CLIP-170 highlights growing microtubule ends in vivo. Cell. 96:1999;517-527. CLIP170 is thought to be an adapter for linking endocytic vesicles to MTs. In this study, GFP-CLIP170 is shown to associate with the growing ends of MTs in vivo.
    • (1999) Cell , vol.96 , pp. 517-527
    • Perez, F.1    Diamantopoulos, G.S.2    Stalder, R.3    Kreis, T.E.4
  • 39
    • 0032769705 scopus 로고    scopus 로고
    • Direct observation of microtubule-F-actin interaction in cell free lysates
    • Development of a promising new system in Xenopus extracts for studying MT-actin interactions is described. Labeled actin filaments align in parallel with MTs and associate preferentially with the MT growing ends. Further, the interaction requires factors present in an isolated MAP fraction, suggesting that proteins normally associated with MT ends may link the MTs and actin filaments
    • Sider J.R., Mandato C.A., Weber K.L., Zandy A.J., Beach D., Finst R.J., Skoble J., Bement W.M. Direct observation of microtubule-F-actin interaction in cell free lysates. J. Cell Science. 112:1999;1947-1956. Development of a promising new system in Xenopus extracts for studying MT-actin interactions is described. Labeled actin filaments align in parallel with MTs and associate preferentially with the MT growing ends. Further, the interaction requires factors present in an isolated MAP fraction, suggesting that proteins normally associated with MT ends may link the MTs and actin filaments.
    • (1999) J. Cell Science , vol.112 , pp. 1947-1956
    • Sider, J.R.1    Mandato, C.A.2    Weber, K.L.3    Zandy, A.J.4    Beach, D.5    Finst, R.J.6    Skoble, J.7    Bement, W.M.8
  • 40
    • 0032572528 scopus 로고    scopus 로고
    • Regulation of cell polarity by microtubules in fission yeast
    • MTs are shown to be required for maintaining polarized actin patch distribution in fission yeast. As MTs and actin both are required for polarized cell growth, feedback signals between MTs and actin may be required to maintain cell polarity
    • Sawin K.E., Nurse P. Regulation of cell polarity by microtubules in fission yeast. J Cell Biol. 142:1998;457-471. MTs are shown to be required for maintaining polarized actin patch distribution in fission yeast. As MTs and actin both are required for polarized cell growth, feedback signals between MTs and actin may be required to maintain cell polarity.
    • (1998) J Cell Biol , vol.142 , pp. 457-471
    • Sawin, K.E.1    Nurse, P.2
  • 41
    • 0030773728 scopus 로고    scopus 로고
    • Tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell
    • Mata J., Nurse P. Tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell. Cell. 89:1997;939-949.
    • (1997) Cell , vol.89 , pp. 939-949
    • Mata, J.1    Nurse, P.2
  • 42
    • 0027403024 scopus 로고
    • Kelch encodes a component of intercellular bridges in Drosophila egg chambers
    • Xue F., Cooley L. Kelch encodes a component of intercellular bridges in Drosophila egg chambers. Cell. 72:1993;681-693.
    • (1993) Cell , vol.72 , pp. 681-693
    • Xue, F.1    Cooley, L.2
  • 43
    • 0030815426 scopus 로고    scopus 로고
    • Microtubule function in morphological differentiation: Growth zones and growth cones
    • Vega L.R., Solomon F. Microtubule function in morphological differentiation: growth zones and growth cones. Cell. 89:1997;825-828.
    • (1997) Cell , vol.89 , pp. 825-828
    • Vega, L.R.1    Solomon, F.2
  • 44
    • 0033005974 scopus 로고    scopus 로고
    • Regulation of cortical structure by the ezrin-radixin-moesin protein family
    • Bretscher A. Regulation of cortical structure by the ezrin-radixin-moesin protein family. Curr Opin Cell Biol. 11:1999;109-116.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 109-116
    • Bretscher, A.1
  • 45
    • 0031954887 scopus 로고    scopus 로고
    • Epithelial and fibroblastoid cells contain numerous cell-type specific putative microtubule-regulating proteins, among which are ezrin and fodrin
    • Shestakova E., Vandekerckhove J., De Mey J.R. Epithelial and fibroblastoid cells contain numerous cell-type specific putative microtubule-regulating proteins, among which are ezrin and fodrin. Eur J Cell Biol. 75:1998;309-320.
    • (1998) Eur J Cell Biol , vol.75 , pp. 309-320
    • Shestakova, E.1    Vandekerckhove, J.2    De Mey, J.R.3
  • 46
    • 0032005305 scopus 로고    scopus 로고
    • Merlin differentially associates with the microtubule and actin cytoskeleton
    • Many ERM proteins can bind to actin filaments directly and are thought to link actin filaments to the plasma membrane. In addition to having an actin-binding domain, the ERM protein merlin contains a separate MT binding domain that is exposed only in the active 'open' conformation of the protein. This raises the possibility that merlin and/or other ERM proteins could help capture MTs at the cell cortex to facilitate directed cell migration
    • Xu H.M., Gutmann D.H. Merlin differentially associates with the microtubule and actin cytoskeleton. J Neuro Res. 51:1998;403-415. Many ERM proteins can bind to actin filaments directly and are thought to link actin filaments to the plasma membrane. In addition to having an actin-binding domain, the ERM protein merlin contains a separate MT binding domain that is exposed only in the active 'open' conformation of the protein. This raises the possibility that merlin and/or other ERM proteins could help capture MTs at the cell cortex to facilitate directed cell migration.
    • (1998) J Neuro Res , vol.51 , pp. 403-415
    • Xu, H.M.1    Gutmann, D.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.