-
1
-
-
43449128899
-
Biochemistry of Tau in Alzheimer's disease and related neurological disorders
-
Sergeant, N., Bretteville, A., Hamdane, M., Caillet-Boudin, M.L., Grognet, P., Bombois, S., Blum, D., Delacourte, A., Pasquier, F., Vanmechelen, E. et al. (2008) Biochemistry of Tau in Alzheimer's disease and related neurological disorders. Expert Rev. Proteomics, 5, 207-224.
-
(2008)
Expert Rev. Proteomics
, vol.5
, pp. 207-224
-
-
Sergeant, N.1
Bretteville, A.2
Hamdane, M.3
Caillet-Boudin, M.L.4
Grognet, P.5
Bombois, S.6
Blum, D.7
Delacourte, A.8
Pasquier, F.9
Vanmechelen, E.10
-
2
-
-
0029034870
-
Tau domains, phosphorylation, and interactions with microtubules
-
discussion 362-3
-
Mandelkow, E.M., Biernat, J., Drewes, G., Gustke, N., Trinczek, B. and Mandelkow, E. (1995) Tau domains, phosphorylation, and interactions with microtubules. Neurobiol. Aging, 16, 355-362; discussion 362-3.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 355-362
-
-
Mandelkow, E.M.1
Biernat, J.2
Drewes, G.3
Gustke, N.4
Trinczek, B.5
Mandelkow, E.6
-
3
-
-
61649085621
-
Tau pathophysiology in neurodegeneration: a tangled issue
-
Spires-Jones, T.L., Stoothoff, W.H., de Calignon, A., Jones, P.B. and Hyman, B.T. (2009) Tau pathophysiology in neurodegeneration: a tangled issue. Trends Neurosci., 32, 150-159.
-
(2009)
Trends Neurosci
, vol.32
, pp. 150-159
-
-
Spires-Jones, T.L.1
Stoothoff, W.H.2
de Calignon, A.3
Jones, P.B.4
Hyman, B.T.5
-
4
-
-
0032476645
-
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
-
Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B. and Mandelkow, E. (1998) Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease. J. Cell Biol., 143, 777-794.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 777-794
-
-
Ebneth, A.1
Godemann, R.2
Stamer, K.3
Illenberger, S.4
Trinczek, B.5
Mandelkow, E.6
-
5
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
Stamer, K., Vogel, R., Thies, E., Mandelkow, E. and Mandelkow, E.M. (2002) Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J. Cell Biol., 156, 1051-1063.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.M.5
-
6
-
-
0032799381
-
Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles
-
Trinczek, B., Ebneth, A., Mandelkow, E.M. and Mandelkow, E. (1999) Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles. J. Cell Sci., 112, 2355-2367.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 2355-2367
-
-
Trinczek, B.1
Ebneth, A.2
Mandelkow, E.M.3
Mandelkow, E.4
-
7
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
Dixit, R., Ross, J.L., Goldman, Y.E. and Holzbaur, E.L. (2008) Differential regulation of dynein and kinesin motor proteins by tau. Science, 319, 1086-1089.
-
(2008)
Science
, vol.319
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.4
-
8
-
-
0037119947
-
Single-molecule investigation of the interference between kinesin, tau and MAP2c
-
Seitz, A., Kojima, H., Oiwa, K., Mandelkow, E.M., Song, Y.H. and Mandelkow, E. (2002) Single-molecule investigation of the interference between kinesin, tau and MAP2c. EMBO J., 21, 4896-4905.
-
(2002)
EMBO J.
, vol.21
, pp. 4896-4905
-
-
Seitz, A.1
Kojima, H.2
Oiwa, K.3
Mandelkow, E.M.4
Song, Y.H.5
Mandelkow, E.6
-
9
-
-
33846118789
-
Multiple-motor based transport and its regulation by Tau
-
Vershinin, M., Carter, B.C., Razafsky, D.S., King, S.J. and Gross, S.P. (2007) Multiple-motor based transport and its regulation by Tau. Proc. Natl Acad. Sci. USA, 104, 87-92.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 87-92
-
-
Vershinin, M.1
Carter, B.C.2
Razafsky, D.S.3
King, S.J.4
Gross, S.P.5
-
10
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
Ishihara, T., Hong, M., Zhang, B., Nakagawa, Y., Lee, M.K., Trojanowski, J.Q. and Lee, V.M. (1999) Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron, 24, 751-762.
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
Lee, V.M.7
-
11
-
-
0342803685
-
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
-
Probst, A., Gotz, J., Wiederhold, K.H., Tolnay, M., Mistl, C., Jaton, A.L., Hong, M., Ishihara, T., Lee, V.M., Trojanowski, J.Q. et al. (2000) Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol., 99, 469-481.
-
(2000)
Acta Neuropathol
, vol.99
, pp. 469-481
-
-
Probst, A.1
Gotz, J.2
Wiederhold, K.H.3
Tolnay, M.4
Mistl, C.5
Jaton, A.L.6
Hong, M.7
Ishihara, T.8
Lee, V.M.9
Trojanowski, J.Q.10
-
12
-
-
0032786370
-
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
-
Spittaels, K., Van den Haute, C., Van Dorpe, J., Bruynseels, K., Vandezande, K., Laenen, I., Geerts, H., Mercken, M., Sciot, R., Van Lommel, A. et al. (1999) Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. Am. J. Pathol., 155, 2153-2165.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 2153-2165
-
-
Spittaels, K.1
Van den Haute, C.2
Van Dorpe, J.3
Bruynseels, K.4
Vandezande, K.5
Laenen, I.6
Geerts, H.7
Mercken, M.8
Sciot, R.9
Van Lommel, A.10
-
13
-
-
0034731461
-
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
-
Spittaels, K., Van den Haute, C., Van Dorpe, J., Geerts, H., Mercken, M., Bruynseels, K., Lasrado, R., Vandezande, K., Laenen, I., Boon, T. et al. (2000) Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice. J. Biol. Chem., 275, 41340-41349.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41340-41349
-
-
Spittaels, K.1
Van den Haute, C.2
Van Dorpe, J.3
Geerts, H.4
Mercken, M.5
Bruynseels, K.6
Lasrado, R.7
Vandezande, K.8
Laenen, I.9
Boon, T.10
-
14
-
-
39549117998
-
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
-
Yuan, A., Kumar, A., Peterhoff, C., Duff, K. and Nixon, R.A. (2008) Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice. J. Neurosci., 28, 1682-1687.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1682-1687
-
-
Yuan, A.1
Kumar, A.2
Peterhoff, C.3
Duff, K.4
Nixon, R.A.5
-
15
-
-
3142592230
-
GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
-
Mudher, A., Shepherd, D., Newman, T.A., Mildren, P., Jukes, J.P., Squire, A., Mears, A., Drummond, J.A., Berg, S., MacKay, D. et al. (2004) GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Mol. Psychiatry, 9, 522-530.
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 522-530
-
-
Mudher, A.1
Shepherd, D.2
Newman, T.A.3
Mildren, P.4
Jukes, J.P.5
Squire, A.6
Mears, A.7
Drummond, J.A.8
Berg, S.9
MacKay, D.10
-
16
-
-
31944434543
-
TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model
-
Khurana, V., Lu, Y., Steinhilb, M.L., Oldham, S., Shulman, J.M. and Feany, M.B. (2006) TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr. Biol., 16, 230-241.
-
(2006)
Curr. Biol.
, vol.16
, pp. 230-241
-
-
Khurana, V.1
Lu, Y.2
Steinhilb, M.L.3
Oldham, S.4
Shulman, J.M.5
Feany, M.B.6
-
17
-
-
33947286683
-
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
-
Fulga, T.A., Elson-Schwab, I., Khurana, V., Steinhilb, M.L., Spires, T.L., Hyman, B.T. and Feany, M.B. (2007) Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat. Cell Biol., 9, 139-148.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 139-148
-
-
Fulga, T.A.1
Elson-Schwab, I.2
Khurana, V.3
Steinhilb, M.L.4
Spires, T.L.5
Hyman, B.T.6
Feany, M.B.7
-
18
-
-
73649106911
-
Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation
-
Anthis, N.J., Haling, J.R., Oxley, C.L., Memo, M., Wegener, K.L., Lim, C.J., Ginsberg, M.H. and Campbell, I.D. (2009) Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation. J. Biol. Chem., 284, 36700-36710.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 36700-36710
-
-
Anthis, N.J.1
Haling, J.R.2
Oxley, C.L.3
Memo, M.4
Wegener, K.L.5
Lim, C.J.6
Ginsberg, M.H.7
Campbell, I.D.8
-
19
-
-
0032550207
-
Kinesin light chains are essential for axonal transport in Drosophila
-
Gindhart, J.G. Jr, Desai, C.J., Beushausen, S., Zinn, K. and Goldstein, L.S. (1998) Kinesin light chains are essential for axonal transport in Drosophila. J. Cell Biol., 141, 443-454.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 443-454
-
-
Gindhart Jr., J.G.1
Desai, C.J.2
Beushausen, S.3
Zinn, K.4
Goldstein, L.S.5
-
20
-
-
0029911064
-
Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila
-
Hurd, D.D. and Saxton, W.M. (1996) Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila. Genetics, 144, 1075-1085.
-
(1996)
Genetics
, vol.144
, pp. 1075-1085
-
-
Hurd, D.D.1
Saxton, W.M.2
-
21
-
-
32544460801
-
Functional dissection of a neuronal network required for cuticle tanning and wing expansion in Drosophila
-
Luan, H., Lemon, W.C., Peabody, N.C., Pohl, J.B., Zelensky, P.K., Wang, D., Nitabach, M.N., Holmes, T.C. and White, B.H. (2006) Functional dissection of a neuronal network required for cuticle tanning and wing expansion in Drosophila. J. Neurosci., 26, 573-584.
-
(2006)
J. Neurosci.
, vol.26
, pp. 573-584
-
-
Luan, H.1
Lemon, W.C.2
Peabody, N.C.3
Pohl, J.B.4
Zelensky, P.K.5
Wang, D.6
Nitabach, M.N.7
Holmes, T.C.8
White, B.H.9
-
22
-
-
77956474155
-
The essential role of bursicon during Drosophila development
-
Loveall, B.J. and Deitcher, D.L. (2010) The essential role of bursicon during Drosophila development. BMC Dev. Biol., 10, 92.
-
(2010)
BMC Dev. Biol.
, vol.10
, pp. 92
-
-
Loveall, B.J.1
Deitcher, D.L.2
-
23
-
-
56649088501
-
Bursicon functions within the Drosophila CNS to modulate wing expansion behavior, hormone secretion, and cell death
-
Peabody, N.C., Diao, F., Luan, H., Wang, H., Dewey, E.M., Honegger, H.W. and White, B.H. (2008) Bursicon functions within the Drosophila CNS to modulate wing expansion behavior, hormone secretion, and cell death. J. Neurosci., 28, 14379-14391.
-
(2008)
J. Neurosci.
, vol.28
, pp. 14379-14391
-
-
Peabody, N.C.1
Diao, F.2
Luan, H.3
Wang, H.4
Dewey, E.M.5
Honegger, H.W.6
White, B.H.7
-
24
-
-
34250317264
-
Tau binding to microtubules does not directly affect microtubule-based vesicle motility
-
Morfini, G., Pigino, G., Mizuno, N., Kikkawa, M. and Brady, S.T. (2007) Tau binding to microtubules does not directly affect microtubule-based vesicle motility. J. Neurosci. Res., 85, 2620-2630.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 2620-2630
-
-
Morfini, G.1
Pigino, G.2
Mizuno, N.3
Kikkawa, M.4
Brady, S.T.5
-
25
-
-
2542464892
-
Modulation of microtubule dynamics by tau in living cells: implications for development and neurodegeneration
-
Bunker, J.M., Wilson, L., Jordan, M.A. and Feinstein, S.C. (2004) Modulation of microtubule dynamics by tau in living cells: implications for development and neurodegeneration. Mol. Biol. Cell, 15, 2720-2728.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2720-2728
-
-
Bunker, J.M.1
Wilson, L.2
Jordan, M.A.3
Feinstein, S.C.4
-
26
-
-
44949259180
-
Complementary dimerization of microtubule-associated tau protein: implications for microtubule bundling and tau-mediated pathogenesis
-
Rosenberg, K.J., Ross, J.L., Feinstein, H.E., Feinstein, S.C. and Israelachvili, J. (2008) Complementary dimerization of microtubule-associated tau protein: implications for microtubule bundling and tau-mediated pathogenesis. Proc. Natl Acad. Sci. USA, 105, 7445-7450.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 7445-7450
-
-
Rosenberg, K.J.1
Ross, J.L.2
Feinstein, H.E.3
Feinstein, S.C.4
Israelachvili, J.5
-
27
-
-
36949040819
-
Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation
-
Liu, F., Li, B., Tung, E.J., Grundke-Iqbal, I., Iqbal, K. and Gong, C.X. (2007) Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation. Eur. J. Neurosci., 26, 3429-3436.
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 3429-3436
-
-
Liu, F.1
Li, B.2
Tung, E.J.3
Grundke-Iqbal, I.4
Iqbal, K.5
Gong, C.X.6
-
28
-
-
33846212717
-
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
-
Wang, J.Z., Grundke-Iqbal, I. and Iqbal, K. (2007) Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. Eur. J. Neurosci., 25, 59-68.
-
(2007)
Eur. J. Neurosci.
, vol.25
, pp. 59-68
-
-
Wang, J.Z.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
29
-
-
77950940279
-
Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein
-
Feuillette, S., Miguel, L., Frebourg, T., Campion, D. and Lecourtois, M. (2010) Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein. J. Neurochem., 113, 895-903.
-
(2010)
J. Neurochem.
, vol.113
, pp. 895-903
-
-
Feuillette, S.1
Miguel, L.2
Frebourg, T.3
Campion, D.4
Lecourtois, M.5
-
30
-
-
77955976865
-
Modelling cell and isoform type specificity of tauopathies in Drosophila
-
Grammenoudi, S., Anezaki, M., Kosmidis, S. and Skoulakis, E.M. (2008) Modelling cell and isoform type specificity of tauopathies in Drosophila. SEB Exp. Biol. Ser., 60, 39-56.
-
(2008)
SEB Exp. Biol. Ser.
, vol.60
, pp. 39-56
-
-
Grammenoudi, S.1
Anezaki, M.2
Kosmidis, S.3
Skoulakis, E.M.4
-
31
-
-
37049027122
-
Tau phosphorylation sites work in concert to promote neurotoxicity in vivo
-
Steinhilb, M.L., Dias-Santagata, D., Fulga, T.A., Felch, D.L. and Feany, M.B. (2007) Tau phosphorylation sites work in concert to promote neurotoxicity in vivo. Mol. Biol. Cell, 18, 5060-5068.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 5060-5068
-
-
Steinhilb, M.L.1
Dias-Santagata, D.2
Fulga, T.A.3
Felch, D.L.4
Feany, M.B.5
-
32
-
-
72949116144
-
Drosophila notal bristle as a novel assessment tool for pathogenic study of Tau toxicity and screening of therapeutic compounds
-
Yeh, P.A., Chien, J.Y., Chou, C.C., Huang, Y.F., Tang, C.Y., Wang, H.Y. and Su, M.T. (2010) Drosophila notal bristle as a novel assessment tool for pathogenic study of Tau toxicity and screening of therapeutic compounds. Biochem. Biophys. Res. Commun., 391, 510-516.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 510-516
-
-
Yeh, P.A.1
Chien, J.Y.2
Chou, C.C.3
Huang, Y.F.4
Tang, C.Y.5
Wang, H.Y.6
Su, M.T.7
-
33
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson, G.R., Wiedau-Pazos, M., Sang, T.K., Wagle, N., Brown, C.A., Massachi, S. and Geschwind, D.H. (2002) Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron, 34, 509-519.
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
34
-
-
1542358895
-
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
-
Nishimura, I., Yang, Y. and Lu, B. (2004) PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila. Cell, 116, 671-682.
-
(2004)
Cell
, vol.116
, pp. 671-682
-
-
Nishimura, I.1
Yang, Y.2
Lu, B.3
-
35
-
-
34248219026
-
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila
-
Steinhilb, M.L., Dias-Santagata, D., Mulkearns, E.E., Shulman, J.M., Biernat, J., Mandelkow, E.M. and Feany, M.B. (2007) S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. J. Neurosci. Res., 85, 1271-1278.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 1271-1278
-
-
Steinhilb, M.L.1
Dias-Santagata, D.2
Mulkearns, E.E.3
Shulman, J.M.4
Biernat, J.5
Mandelkow, E.M.6
Feany, M.B.7
-
36
-
-
57649203362
-
Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model
-
Chatterjee, S., Sang, T.K., Lawless, G.M. and Jackson, G.R. (2009) Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model. Hum. Mol. Genet., 18, 164-177.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 164-177
-
-
Chatterjee, S.1
Sang, T.K.2
Lawless, G.M.3
Jackson, G.R.4
-
37
-
-
3242769327
-
Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila
-
Franco, B., Bogdanik, L., Bobinnec, Y., Debec, A., Bockaert, J., Parmentier, M.L. and Grau, Y. (2004) Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila. J. Neurosci., 24, 6573-6577.
-
(2004)
J. Neurosci.
, vol.24
, pp. 6573-6577
-
-
Franco, B.1
Bogdanik, L.2
Bobinnec, Y.3
Debec, A.4
Bockaert, J.5
Parmentier, M.L.6
Grau, Y.7
|