-
1
-
-
0036892302
-
Tau gene mutations: Dissecting the pathogenesis of FTDP-17
-
Ingram, E.M. and Spillantini, M.G. (2002) Tau gene mutations: Dissecting the pathogenesis of FTDP-17. Trends Mol. Med., 8, 555-562.
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 555-562
-
-
Ingram, E.M.1
Spillantini, M.G.2
-
2
-
-
0034940160
-
Neurodegenerative tauopathies
-
Lee, V.M.Y., Goedert, M. and Trojanowski, J.Q. (2001) Neurodegenerative tauopathies. Ann. Rev. Neurosci., 24, 1121-1159.
-
(2001)
Ann. Rev. Neurosci.
, vol.24
, pp. 1121-1159
-
-
Lee, V.M.Y.1
Goedert, M.2
Trojanowski, J.Q.3
-
3
-
-
0031949084
-
Frontotemporal dementia and Parkinsonism linked to chromosome 17: A new group of tauopathies
-
Spillantini, M.G., Bird, T.D. and Ghetti, B. (1998) Frontotemporal dementia and Parkinsonism linked to chromosome 17: A new group of tauopathies. Brain Pathol., 8, 387-402.
-
(1998)
Brain Pathol.
, vol.8
, pp. 387-402
-
-
Spillantini, M.G.1
Bird, T.D.2
Ghetti, B.3
-
4
-
-
0032543684
-
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton, M., Lendon, C.L., Rizzu, P., Baker, M., Froelich, S., Houlden, H., Pickering-Brown, S., Chakraverty, S., Isaacs, A., Grover, A. et al. (1998) Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature, 393, 702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
-
5
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia
-
Poorkaj, P., Bird, T.D., Wijsman, E., Nemens, E., Garruto, R.M., Anderson, L., Andreadis, A., Wiederholt, W.C., Raskind, M. and Schellenberg, G.D. (1998) Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann. Neurol., 43, 815-825.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
Anderson, L.6
Andreadis, A.7
Wiederholt, W.C.8
Raskind, M.9
Schellenberg, G.D.10
-
6
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
Spillantini, M.G., Murrell, J.R., Goedert, M., Farlow, M.R., Klug, A. and Ghetti, B. (1998) Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc. Natl Acad. Sci. USA, 95, 7737-7741.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
7
-
-
14244261725
-
Axonal transport defects: A common theme in neurodegenerative diseases
-
Roy, S., Zhang, B., Lee, V.M.Y. and Trojanowski, J.Q. (2005) Axonal transport defects: A common theme in neurodegenerative diseases. Acta Neuropathol., 109, 5-13.
-
(2005)
Acta Neuropathol.
, vol.109
, pp. 5-13
-
-
Roy, S.1
Zhang, B.2
Lee, V.M.Y.3
Trojanowski, J.Q.4
-
8
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
Stamer, K., Vogel, R., Thies, E., Mandelkow, E. and Mandelkow, E.M. (2002) Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J. Cell Biol., 156, 1051-1063.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.M.5
-
9
-
-
0032484089
-
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17
-
Hong, M., Zhukareva, V., Vogelsberg-Ragaglia, V., Wszolek, Z., Reed, L., Miller, B.I., Geschwind, D.H., Bird, T.D., McKeel, D., Goate, A. et al. (1998) Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. Science, 282, 1914-1917.
-
(1998)
Science
, vol.282
, pp. 1914-1917
-
-
Hong, M.1
Zhukareva, V.2
Vogelsberg-Ragaglia, V.3
Wszolek, Z.4
Reed, L.5
Miller, B.I.6
Geschwind, D.H.7
Bird, T.D.8
McKeel, D.9
Goate, A.10
-
10
-
-
0032919462
-
Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments
-
Goedert, M., Jakes, R. and Crowther, R.A. (1999) Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments. FEBS Lett., 450, 306-311.
-
(1999)
FEBS Lett.
, vol.450
, pp. 306-311
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
-
11
-
-
0033011181
-
Accelerated filament formation from tau protein with specific FTDP-17 missense mutations
-
Nacharaju, P., Lewis, J., Easson, C., Yen, S., Hackett, J., Hutton, M. and Yen, S.H. (1999) Accelerated filament formation from tau protein with specific FTDP-17 missense mutations. FEBS Lett., 447, 195-199.
-
(1999)
FEBS Lett.
, vol.447
, pp. 195-199
-
-
Nacharaju, P.1
Lewis, J.2
Easson, C.3
Yen, S.4
Hackett, J.5
Hutton, M.6
Yen, S.H.7
-
12
-
-
0033850407
-
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
-
Buee, L., Bussiere, T., Buee-Scherrer, V., Delacourte, A. and Hof, P.R. (2000) Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res. Rev., 33, 95-130.
-
(2000)
Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buee, L.1
Bussiere, T.2
Buee-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
13
-
-
0042889049
-
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy
-
Kraemer, B.C., Zhang, B., Leverenz, J.B., Thomas, J.H., Trojanowski, J.Q. and Schellenberg, G.D. (2003) Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy. Proc. Natl Acad. Sci. USA, 100, 9980-9985.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 9980-9985
-
-
Kraemer, B.C.1
Zhang, B.2
Leverenz, J.B.3
Thomas, J.H.4
Trojanowski, J.Q.5
Schellenberg, G.D.6
-
14
-
-
0030989110
-
Aex-3 encodes a novel regulator of presynaptic activity in C. elegans
-
Iwasaki, K.K., Staunton, J., Saifee, O., Nonet, M. and Thomas, J.H. (1997) aex-3 encodes a novel regulator of presynaptic activity in C. elegans. Neuron, 18, 613-622.
-
(1997)
Neuron
, vol.18
, pp. 613-622
-
-
Iwasaki, K.K.1
Staunton, J.2
Saifee, O.3
Nonet, M.4
Thomas, J.H.5
-
15
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath, R.S., Fraser, A.G., Dong, Y., Poulin, G., Durbin, R., Gotta, M., Kanapin, A., Le Bot, N., Moreno, S., Sohrmann, M. et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature, 421, 231-237.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
Gotta, M.6
Kanapin, A.7
Le Bot, N.8
Moreno, S.9
Sohrmann, M.10
-
16
-
-
0031840035
-
Unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors
-
Prasad, B.C., Ye, B., Zackhary, R., Schrader, K., Seydoux, G. and Reed, R.R. (1998) unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors. Development, 125, 1561-1568.
-
(1998)
Development
, vol.125
, pp. 1561-1568
-
-
Prasad, B.C.1
Ye, B.2
Zackhary, R.3
Schrader, K.4
Seydoux, G.5
Reed, R.R.6
-
17
-
-
0030965832
-
The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation
-
Bloom, L. and Horvitz, H.R. (1997) The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation. Proc. Natl Acad. Sci. USA, 94, 3414-3419.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 3414-3419
-
-
Bloom, L.1
Horvitz, H.R.2
-
18
-
-
0035911962
-
The Caenorhabditis elegans unc-78 gene encodes a homologue of actin-interacting protein 1 required for organized assembly of muscle actin filaments
-
Ono, S. (2001) The Caenorhabditis elegans unc-78 gene encodes a homologue of actin-interacting protein 1 required for organized assembly of muscle actin filaments. J. Cell Biol., 152, 1313-1319.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 1313-1319
-
-
Ono, S.1
-
19
-
-
0018961312
-
Mutants with altered muscle structure of Caenorhabditis elegans
-
Waterston, R.H., Thomson, J.N. and Brenner, S. (1980) Mutants with altered muscle structure of Caenorhabditis elegans. Dev. Biol., 77, 271-302.
-
(1980)
Dev. Biol.
, vol.77
, pp. 271-302
-
-
Waterston, R.H.1
Thomson, J.N.2
Brenner, S.3
-
20
-
-
0035879075
-
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase
-
Mudher, A., Chapman, S., Richardson, J., Asuni, A., Gibb, G., Pollard, C., Killick, R., Iqbal, T., Raymond, L., Varndell, I. et al. (2001) Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. J. Neurosci., 21, 4987-4995.
-
(2001)
J. Neurosci.
, vol.21
, pp. 4987-4995
-
-
Mudher, A.1
Chapman, S.2
Richardson, J.3
Asuni, A.4
Gibb, G.5
Pollard, C.6
Killick, R.7
Iqbal, T.8
Raymond, L.9
Varndell, I.10
-
21
-
-
0035896451
-
Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau
-
Tomizawa, K., Omori, A., Ohtake, A., Sato, K. and Takahashi, M. (2001) Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau. FEBS Lett., 492, 221-227.
-
(2001)
FEBS Lett.
, vol.492
, pp. 221-227
-
-
Tomizawa, K.1
Omori, A.2
Ohtake, A.3
Sato, K.4
Takahashi, M.5
-
22
-
-
0036312496
-
Involvement of glycogen synthase kinase-3 beta and tau phosphorylation in neuronal Golgi disassembly
-
Elyaman, W., Yardin, C. and Hugon, J. (2002) Involvement of glycogen synthase kinase-3 beta and tau phosphorylation in neuronal Golgi disassembly. J. Neurochem., 81, 870-880.
-
(2002)
J. Neurochem.
, vol.81
, pp. 870-880
-
-
Elyaman, W.1
Yardin, C.2
Hugon, J.3
-
23
-
-
0032987650
-
Phosphorylation of tau protein by recombinant GSK-3 beta: Pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain
-
Godemann, R., Biernat, J., Mandelkow, E. and Mandelkow, E.M. (1999) Phosphorylation of tau protein by recombinant GSK-3 beta: Pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain. FEBS Lett., 454, 157-164.
-
(1999)
FEBS Lett.
, vol.454
, pp. 157-164
-
-
Godemann, R.1
Biernat, J.2
Mandelkow, E.3
Mandelkow, E.M.4
-
24
-
-
0032502829
-
Characterization of tau phosphorylation in glycogen synthase kinase-3 beta and cyclin dependent kinase-5 activator (p23) transfected cells
-
Michel, G., Mercken, M., Murayama, M., Noguchi, K., Ishiguro, K., Imahori, K. and Takashima, A. (1998) Characterization of tau phosphorylation in glycogen synthase kinase-3 beta and cyclin dependent kinase-5 activator (p23) transfected cells. Biochim. Biophys. Acta, 1380, 177-182.
-
(1998)
Biochim. Biophys. Acta
, vol.1380
, pp. 177-182
-
-
Michel, G.1
Mercken, M.2
Murayama, M.3
Noguchi, K.4
Ishiguro, K.5
Imahori, K.6
Takashima, A.7
-
25
-
-
0037479006
-
-
Wiley, West Sussex, UK
-
Iqbal, K., Sisodia, S.S. and Winblad, B. (2001) Alzheimer's Disease. Wiley, West Sussex, UK, pp. 609-620.
-
(2001)
Alzheimer's Disease
, pp. 609-620
-
-
Iqbal, K.1
Sisodia, S.S.2
Winblad, B.3
-
26
-
-
0037023679
-
Glycogen synthase kinase-3 beta is complexed with tau protein in brain microtubules
-
Sun, W., Qureshi, H.Y., Cafferty, P.W., Sobue, K., Agarwalmawal, A., Neufield, K.D. and Paudel, H.K. (2002) Glycogen synthase kinase-3 beta is complexed with tau protein in brain microtubules. J. Biol. Chem., 277, 11933-11940.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11933-11940
-
-
Sun, W.1
Qureshi, H.Y.2
Cafferty, P.W.3
Sobue, K.4
Agarwalmawal, A.5
Neufield, K.D.6
Paudel, H.K.7
-
27
-
-
0032566623
-
Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase
-
Wang, J.Z., Wu, Q.L., Smith, A., Grundke-Iqbal, I. and Iqbal, K. (1998) Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase. FEBS Lett., 436, 28-34.
-
(1998)
FEBS Lett.
, vol.436
, pp. 28-34
-
-
Wang, J.Z.1
Wu, Q.L.2
Smith, A.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
28
-
-
1542358895
-
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
-
Nishimura, I., Yang, Y.F. and Lu, B.W. (2004) PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila. Cell, 116, 671-682.
-
(2004)
Cell
, vol.116
, pp. 671-682
-
-
Nishimura, I.1
Yang, Y.F.2
Lu, B.W.3
-
29
-
-
0141530895
-
MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1
-
Timm, T., Li, X.Y., Biernat, J., Jiao, J., Mandelkow, E., Vandekerckhove, J. and Mandelkow, E.M. (2003) MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1. EMBO J., 22, 5090-5101.
-
(2003)
EMBO J.
, vol.22
, pp. 5090-5101
-
-
Timm, T.1
Li, X.Y.2
Biernat, J.3
Jiao, J.4
Mandelkow, E.5
Vandekerckhove, J.6
Mandelkow, E.M.7
-
30
-
-
0030969575
-
MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption
-
Drewes, G., Ebneth, A., Preuss, U., Mandelkow, E.M. and Mandelkow, E. (1997) MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. Cell, 89, 297-308.
-
(1997)
Cell
, vol.89
, pp. 297-308
-
-
Drewes, G.1
Ebneth, A.2
Preuss, U.3
Mandelkow, E.M.4
Mandelkow, E.5
-
31
-
-
0028568076
-
An immunohistochemical study of cathepsin E in Alzheimer-type dementia brains
-
Bernstein, H.G. and Wiederanders, B. (1994) An immunohistochemical study of cathepsin E in Alzheimer-type dementia brains. Brain Res., 667, 287-290.
-
(1994)
Brain Res.
, vol.667
, pp. 287-290
-
-
Bernstein, H.G.1
Wiederanders, B.2
-
32
-
-
0345434817
-
Regional distribution of nicotinic receptor subunit mRNAs in human brain: Comparison between Alzheimer and normal brain
-
Hellstromlindahl, E., Mousavi, M., Zhang, X., Ravid, R. and Nordberg, A. (1999) Regional distribution of nicotinic receptor subunit mRNAs in human brain: Comparison between Alzheimer and normal brain. Mol. Brain Res., 66, 94-103.
-
(1999)
Mol. Brain Res.
, vol.66
, pp. 94-103
-
-
Hellstromlindahl, E.1
Mousavi, M.2
Zhang, X.3
Ravid, R.4
Nordberg, A.5
-
33
-
-
0037440372
-
Alzheimer's disease is associated with a selective increase in alpha 7 nicotinic acetylcholine receptor immunoreactivity in astrocytes
-
Teaktong, T., Graham, A., Court, J., Perry, R., Jaros, E., Johnson, M., Hall, R. and Perry, E. (2003) Alzheimer's disease is associated with a selective increase in alpha 7 nicotinic acetylcholine receptor immunoreactivity in astrocytes. Glia, 41, 207-211.
-
(2003)
Glia
, vol.41
, pp. 207-211
-
-
Teaktong, T.1
Graham, A.2
Court, J.3
Perry, R.4
Jaros, E.5
Johnson, M.6
Hall, R.7
Perry, E.8
-
34
-
-
0042357192
-
alpha(7) nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation
-
Wang, H.Y., Li, W.W., Benedetti, N.J. and Lee, D.H.S. (2003) alpha(7) nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation. J. Biol. Chem., 278, 31547-31553.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31547-31553
-
-
Wang, H.Y.1
Li, W.W.2
Benedetti, N.J.3
Lee, D.H.S.4
-
35
-
-
0027753055
-
Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A
-
Drewes, G., Mandelkow, E.M., Baumann, K., Goris, J., Merlevede, W. and Mandelkow, E. (1993) Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A. FEBS Lett., 336, 425-432.
-
(1993)
FEBS Lett.
, vol.336
, pp. 425-432
-
-
Drewes, G.1
Mandelkow, E.M.2
Baumann, K.3
Goris, J.4
Merlevede, W.5
Mandelkow, E.6
-
36
-
-
0028885494
-
Protein phosphatase 2A is the major enzyme in brain that dephosphorylates tau protein phosphorylated by proline-directed protein kinases or cyclic AMP-dependent protein kinase
-
Goedert, M., Jakes, R., Qi, Z., Wang, J.H. and Cohen, P. (1995) Protein phosphatase 2A is the major enzyme in brain that dephosphorylates tau protein phosphorylated by proline-directed protein kinases or cyclic AMP-dependent protein kinase. J. Neurochem., 65, 2804-2807.
-
(1995)
J. Neurochem.
, vol.65
, pp. 2804-2807
-
-
Goedert, M.1
Jakes, R.2
Qi, Z.3
Wang, J.H.4
Cohen, P.5
-
37
-
-
0033520355
-
Molecular interactions among protein phosphatase 2A, tau, and microtubules-implications for the regulation of tau phosphorylation and the development of tauopathies
-
Sontag, E., Nunbhakdi-Craig, V., Lee, G., Brandt, R., Kamibayashi, C., Kuret, J., White, C.L., Mumby, M.C. and Bloom, G.S. (1999) Molecular interactions among protein phosphatase 2A, tau, and microtubules-implications for the regulation of tau phosphorylation and the development of tauopathies. J. Biol. Chem., 274, 25490-25498.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25490-25498
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Lee, G.3
Brandt, R.4
Kamibayashi, C.5
Kuret, J.6
White, C.L.7
Mumby, M.C.8
Bloom, G.S.9
-
38
-
-
11144356089
-
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
-
Petrucelli, L., Dickson, D., Kehoe, K., Taylor, J., Snyder, H., Grover, A., DeLucia, M., McGowan, E., Lewis, J., Prihar, G. et al. (2004) CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Hum. Mol. Genet., 13, 703-714.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 703-714
-
-
Petrucelli, L.1
Dickson, D.2
Kehoe, K.3
Taylor, J.4
Snyder, H.5
Grover, A.6
DeLucia, M.7
McGowan, E.8
Lewis, J.9
Prihar, G.10
-
39
-
-
1042266624
-
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival
-
Shimura, H., Schwartz, D., Gygi, S.P. and Kosik, K.S. (2004) CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. J. Biol. Chem., 279, 4869-4876.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4869-4876
-
-
Shimura, H.1
Schwartz, D.2
Gygi, S.P.3
Kosik, K.S.4
-
40
-
-
17144395539
-
Triggers of full-length tau aggregation: A role for partially folded intermediates
-
Chirita, C.N., Congdon, E.E., Yin, H.S. and Kuret, J. (2005) Triggers of full-length tau aggregation: A role for partially folded intermediates. Biochemistry, 44, 5862-5872.
-
(2005)
Biochemistry
, vol.44
, pp. 5862-5872
-
-
Chirita, C.N.1
Congdon, E.E.2
Yin, H.S.3
Kuret, J.4
-
41
-
-
27644478606
-
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
-
Liu, F., GrundkeIqbal, I., Iqbal, K. and Gong, C.X. (2005) Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur. J. Neurosci., 22, 1942-1950.
-
(2005)
Eur. J. Neurosci.
, vol.22
, pp. 1942-1950
-
-
Liu, F.1
GrundkeIqbal, I.2
Iqbal, K.3
Gong, C.X.4
-
42
-
-
0028937631
-
Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark): A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262
-
Drewes, G., Trinczek, B., Illenberger, S., Biernat, J., Schmitt-Ulms, G., Meyer, H.E., Mandelkow, E.M. and Mandelkow, E. (1995) Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark): A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262. J. Biol. Chem., 270, 7679-7688.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7679-7688
-
-
Drewes, G.1
Trinczek, B.2
Illenberger, S.3
Biernat, J.4
Schmitt-Ulms, G.5
Meyer, H.E.6
Mandelkow, E.M.7
Mandelkow, E.8
-
43
-
-
0033792070
-
Structural and functional implications of tau hyperphosphorylation: Information from phosphorylation-mimicking mutated tau proteins
-
Eidenmuller, J., Fath, T., Hellwig, A., Reed, J., Sontag, E. and Brandt, R. (2000) Structural and functional implications of tau hyperphosphorylation: Information from phosphorylation-mimicking mutated tau proteins. Biochemistry, 39, 13166-13175.
-
(2000)
Biochemistry
, vol.39
, pp. 13166-13175
-
-
Eidenmuller, J.1
Fath, T.2
Hellwig, A.3
Reed, J.4
Sontag, E.5
Brandt, R.6
-
44
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
-
Schneider, A., Biernat, J., Vonbergen, M., Mandelkow, E. and Mandelkow, E.M. (1999) Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments. Biochemistry, 38, 3549-3558.
-
(1999)
Biochemistry
, vol.38
, pp. 3549-3558
-
-
Schneider, A.1
Biernat, J.2
Vonbergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
45
-
-
0027338266
-
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
-
Biernat, J., Gustke, N., Drewes, G., Mandelkow, E.M. and Mandelkow, E. (1993) Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding. Neuron, 11, 153-163.
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.M.4
Mandelkow, E.5
-
46
-
-
0035425347
-
Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein
-
Eidenmuller, J., Fath, T., Maas, T., Pool, M., Sontag, E. and Brandt, R. (2001) Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein. Biochem. J., 357, 759-767.
-
(2001)
Biochem. J.
, vol.357
, pp. 759-767
-
-
Eidenmuller, J.1
Fath, T.2
Maas, T.3
Pool, M.4
Sontag, E.5
Brandt, R.6
-
47
-
-
1642280378
-
Pseudophosphorylation of tau protein alters its ability for self-aggregation
-
Haase, C., Stieler, J.T., Arendt, T. and Holzer, M. (2004) Pseudophosphorylation of tau protein alters its ability for self-aggregation. J. Neurochem., 88, 1509-1520.
-
(2004)
J. Neurochem.
, vol.88
, pp. 1509-1520
-
-
Haase, C.1
Stieler, J.T.2
Arendt, T.3
Holzer, M.4
-
48
-
-
14244258737
-
Site-specific pseudophosphorylation modulates the rate of tau filament dissociation
-
Necula, M. and Kuret, J. (2005) Site-specific pseudophosphorylation modulates the rate of tau filament dissociation. FEBS Lett., 579, 1453-1457.
-
(2005)
FEBS Lett.
, vol.579
, pp. 1453-1457
-
-
Necula, M.1
Kuret, J.2
-
49
-
-
0040299037
-
AD2, a phosphorylation-dependent monoclonal antibody directed against tau proteins found in Alzheimer's disease
-
Buee-Scherrer, V., Condamines, O., Mourton-Gilles, C., Jakes, R., Goedert, M., Pau, B. and Delacourte, A. (1996) AD2, a phosphorylation-dependent monoclonal antibody directed against tau proteins found in Alzheimer's disease. Brain Res. Mol. Brain Res., 39, 79-88.
-
(1996)
Brain Res. Mol. Brain Res.
, vol.39
, pp. 79-88
-
-
Buee-Scherrer, V.1
Condamines, O.2
Mourton-Gilles, C.3
Jakes, R.4
Goedert, M.5
Pau, B.6
Delacourte, A.7
-
50
-
-
9644273963
-
Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro
-
Necula, M. and Kuret, J. (2004) Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro. J. Biol. Chem., 279, 49694-49703.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49694-49703
-
-
Necula, M.1
Kuret, J.2
-
51
-
-
0036937699
-
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
-
Augustinack, J.C., Schneider, A., Mandelkow, E.M. and Hyman, B.T. (2002) Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathol., 103, 26-35.
-
(2002)
Acta Neuropathol.
, vol.103
, pp. 26-35
-
-
Augustinack, J.C.1
Schneider, A.2
Mandelkow, E.M.3
Hyman, B.T.4
-
52
-
-
0027361281
-
Microtubule-associated protein tau: Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease
-
Kopke, E., Tung, Y.C., Shaikh, S., Alonso, A.C., Iqbal, K. and Grundke-Iqbal, I. (1993) Microtubule-associated protein tau: Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. J. Biol. Chem., 268, 24374-24384.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24374-24384
-
-
Kopke, E.1
Tung, Y.C.2
Shaikh, S.3
Alonso, A.C.4
Iqbal, K.5
Grundke-Iqbal, I.6
-
53
-
-
0026676007
-
Phosphate analysis and dephosphorylation of modified tau associated with paired helical filaments
-
Ksiezak-Reding, H., Liu, W.K. and Yen, S.H. (1992) Phosphate analysis and dephosphorylation of modified tau associated with paired helical filaments. Brain Res., 597, 209-219.
-
(1992)
Brain Res.
, vol.597
, pp. 209-219
-
-
Ksiezak-Reding, H.1
Liu, W.K.2
Yen, S.H.3
-
54
-
-
4644360412
-
MARKing tau for tangles and toxicity
-
Drewes, G. (2004) MARKing tau for tangles and toxicity. Trends Biochem. Sci., 29, 548-555.
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 548-555
-
-
Drewes, G.1
-
55
-
-
11844260672
-
Both the establishment and the maintenance of neuronal polarity require active mechanisms: Critical roles of GSK-3beta and its upstream regulators
-
Jiang, H., Guo, W., Liang, X. and Rao, Y. (2005) Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators. Cell, 120, 123-135.
-
(2005)
Cell
, vol.120
, pp. 123-135
-
-
Jiang, H.1
Guo, W.2
Liang, X.3
Rao, Y.4
-
56
-
-
11844297771
-
GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity
-
Yoshimura, T., Kawano, Y., Arimura, N., Kawabata, S., Kikuchi, A. and Kaibuchi, K. (2005) GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity. Cell, 120, 137-149.
-
(2005)
Cell
, vol.120
, pp. 137-149
-
-
Yoshimura, T.1
Kawano, Y.2
Arimura, N.3
Kawabata, S.4
Kikuchi, A.5
Kaibuchi, K.6
-
57
-
-
1642363745
-
Spatial learning deficit in transgenic mice that conditionally over-express GSK-3 beta in the brain but do not form tau filaments
-
Hernandez, F., Borrell, J., Guaza, C., Avila, J. and Lucas, J.J. (2002) Spatial learning deficit in transgenic mice that conditionally over-express GSK-3 beta in the brain but do not form tau filaments. J. Neurochem., 83, 1529-1533.
-
(2002)
J. Neurochem.
, vol.83
, pp. 1529-1533
-
-
Hernandez, F.1
Borrell, J.2
Guaza, C.3
Avila, J.4
Lucas, J.J.5
-
58
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3 beta conditional transgenic mice
-
Lucas, J.L., Hernandez, F., Gomezramos, P., Moran, M.A., Hen, R. and Avila, J. (2001) Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3 beta conditional transgenic mice. EMBO J., 20, 27-39.
-
(2001)
EMBO J.
, vol.20
, pp. 27-39
-
-
Lucas, J.L.1
Hernandez, F.2
Gomezramos, P.3
Moran, M.A.4
Hen, R.5
Avila, J.6
-
59
-
-
0030830304
-
Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3 beta transgenes
-
Brownlees, J., Irving, N.G., Brion, J.P., Gibb, B.J.M., Wagner, U., Woodgett, J. and Miller, C.C.J. (1997) Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3 beta transgenes. Neuroreport, 8, 3251-3255.
-
(1997)
Neuroreport
, vol.8
, pp. 3251-3255
-
-
Brownlees, J.1
Irving, N.G.2
Brion, J.P.3
Gibb, B.J.M.4
Wagner, U.5
Woodgett, J.6
Miller, C.C.J.7
-
60
-
-
4444281337
-
Overexpression of GSK3 beta(S9A) resulted in tau hyperphosphorylation and morphology reminiscent of pretangle-like neurons in the brain of PDGSK3 beta transgenic mice
-
Li, B.L., Ryder, J., Su, Y., Moore, S.A., Liu, F., Solenberg, P., Brune, K., Fox, N., Ni, B.H., Liu, R.G. and Zhou, Y. (2004) Overexpression of GSK3 beta(S9A) resulted in tau hyperphosphorylation and morphology reminiscent of pretangle-like neurons in the brain of PDGSK3 beta transgenic mice. Transgenic Res., 13, 385-396.
-
(2004)
Transgenic Res.
, vol.13
, pp. 385-396
-
-
Li, B.L.1
Ryder, J.2
Su, Y.3
Moore, S.A.4
Liu, F.5
Solenberg, P.6
Brune, K.7
Fox, N.8
Ni, B.H.9
Liu, R.G.10
Zhou, Y.11
-
61
-
-
0032786370
-
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
-
Spittaels, K., Van den Haute, C., Van Dorpe, J., Bruynseels, K., Vandezande, K., Laenen, I., Geerts, H., Mercken, M., Sciot, R., Van Lommel, A., Loos, R. and Van Leuven, F. (1999) Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. Am. J. Pathol., 155, 2153-2165.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 2153-2165
-
-
Spittaels, K.1
Van den Haute, C.2
Van Dorpe, J.3
Bruynseels, K.4
Vandezande, K.5
Laenen, I.6
Geerts, H.7
Mercken, M.8
Sciot, R.9
Van Lommel, A.10
Loos, R.11
Van Leuven, F.12
-
62
-
-
0036008557
-
Coexpression of GSK-3 beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau
-
Nuydens, R., Van den Kieboom, G., Nolten, C., Verhulst, C., Vanosta, P., Spittaels, K., Vandenhaute, C., Defeyter, E., Geerts, H. and Van Leuven, F. (2002) Coexpression of GSK-3 beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau. Neurobiol. Dis., 9, 38-48.
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 38-48
-
-
Nuydens, R.1
Van den Kieboom, G.2
Nolten, C.3
Verhulst, C.4
Vanosta, P.5
Spittaels, K.6
Vandenhaute, C.7
Defeyter, E.8
Geerts, H.9
Van Leuven, F.10
-
63
-
-
0034731461
-
Glycogen synthase kinase-3 beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
-
Spittaels, K., Van den Haute, C., Van Dorpe, J., Geerts, H., Mercken, M., Bruynseels, K., Lasrado, R., Vandezande, K., Laenen, I., Boon, T. et al. (2000) Glycogen synthase kinase-3 beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice. J. Biol. Chem., 275, 41340-41349.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41340-41349
-
-
Spittaels, K.1
Van den Haute, C.2
Van Dorpe, J.3
Geerts, H.4
Mercken, M.5
Bruynseels, K.6
Lasrado, R.7
Vandezande, K.8
Laenen, I.9
Boon, T.10
-
64
-
-
21044449225
-
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
-
Noble, W., Planel, E., Zehr, C., Olm, V., Meyerson, J., Suleman, F., Gaynor, K., Wang, L., Lafrancois, J., Feinstein, B. et al. (2005) Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl Acad. Sci. USA, 102, 6990-6995.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 6990-6995
-
-
Noble, W.1
Planel, E.2
Zehr, C.3
Olm, V.4
Meyerson, J.5
Suleman, F.6
Gaynor, K.7
Wang, L.8
Lafrancois, J.9
Feinstein, B.10
-
65
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson, G.R., Wiedau-Pazos, M., Sang, T.K., Wagle, N., Brown, C.A., Massachi, S. and Geschwind, D.H. (2002) Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron, 34, 509-519.
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
66
-
-
3142592230
-
GSK-3 beta inhibition reverses axonal transport defects and behavioral phenotypes in Drosophila
-
Mudher, A., Shepherd, D., Newman, T.A., Mildren, P., Jukes, J.P., Squire, A., Mears, A., Berg, S., MacKay, D., Asuni, A.A., Bhat, R. and Lovestone, S. (2004) GSK-3 beta inhibition reverses axonal transport defects and behavioral phenotypes in Drosophila. Mol. Psychiatry, 9, 522-530.
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 522-530
-
-
Mudher, A.1
Shepherd, D.2
Newman, T.A.3
Mildren, P.4
Jukes, J.P.5
Squire, A.6
Mears, A.7
Berg, S.8
MacKay, D.9
Asuni, A.A.10
Bhat, R.11
Lovestone, S.12
-
67
-
-
0346361872
-
Genetic modifiers of tauopathy in Drosophila
-
Shulman, J.M. and Feany, M.B. (2003) Genetic modifiers of tauopathy in Drosophila. Genetics, 165, 1233-1242.
-
(2003)
Genetics
, vol.165
, pp. 1233-1242
-
-
Shulman, J.M.1
Feany, M.B.2
-
68
-
-
24644487812
-
Endoplasmic reticulum stress response and neurodegeneration
-
Paschen, W. and Mengesdorf, T. (2005) Endoplasmic reticulum stress response and neurodegeneration. Cell Calcium, 38, 409-415.
-
(2005)
Cell Calcium
, vol.38
, pp. 409-415
-
-
Paschen, W.1
Mengesdorf, T.2
-
69
-
-
0033013126
-
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
-
Ballinger, C.A., Connell, P., Wu, Y., Hu, Z., Thompson, L.J., Yin, L.Y. and Patterson, C. (1999) Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol. Cell Biol., 19, 4535-4545.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 4535-4545
-
-
Ballinger, C.A.1
Connell, P.2
Wu, Y.3
Hu, Z.4
Thompson, L.J.5
Yin, L.Y.6
Patterson, C.7
-
70
-
-
5444239863
-
U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy
-
Hatakeyama, S., Matsumoto, M., Kamura, T., Murayama, M., Chui, D.H., Planel, E., Takahashi, R., Nakayama, K.I. and Takashima, A. (2004) U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy. J. Neurochem., 91, 299-307.
-
(2004)
J. Neurochem.
, vol.91
, pp. 299-307
-
-
Hatakeyama, S.1
Matsumoto, M.2
Kamura, T.3
Murayama, M.4
Chui, D.H.5
Planel, E.6
Takahashi, R.7
Nakayama, K.I.8
Takashima, A.9
-
71
-
-
26944463072
-
Progressive neurodegeneration in C. elegans model of tauopathy
-
Miyasaka, T., Ding, Z., Gengyo-Ando, K., Oue, M., Yamaguchi, H., Mitani, S. and Ihara, Y. (2005) Progressive neurodegeneration in C. elegans model of tauopathy. Neurobiol. Dis., 20, 372-383.
-
(2005)
Neurobiol. Dis.
, vol.20
, pp. 372-383
-
-
Miyasaka, T.1
Ding, Z.2
Gengyo-Ando, K.3
Oue, M.4
Yamaguchi, H.5
Mitani, S.6
Ihara, Y.7
-
72
-
-
17744372861
-
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
-
Pirkkala, L., Nykanen, P. and Sistonen, L. (2001) Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J., 15, 1118-1131.
-
(2001)
FASEB J.
, vol.15
, pp. 1118-1131
-
-
Pirkkala, L.1
Nykanen, P.2
Sistonen, L.3
-
74
-
-
11144261132
-
Proteasome inhibition and tau proteolysis: An unexpected regulation
-
Delobel, P., Leroy, O., Hamdane, M., Sambo, A.V., Delacourte, A. and Buee, L. (2005) Proteasome inhibition and tau proteolysis: An unexpected regulation. FEBS Lett., 579, 1-5.
-
(2005)
FEBS Lett.
, vol.579
, pp. 1-5
-
-
Delobel, P.1
Leroy, O.2
Hamdane, M.3
Sambo, A.V.4
Delacourte, A.5
Buee, L.6
-
75
-
-
25444481075
-
A gene expression fingerprint of C. elegans embryonic motor neurons
-
Fox, R.M., Von Stetina, S.E., Barlow, S.J., Shaffer, C., Olszewski, K.L., Moore, J.H., Dupuy, D., Vidal, M. and Miller, D.M., III (2005) A gene expression fingerprint of C. elegans embryonic motor neurons. BMC Genomics, 6, 42.
-
(2005)
BMC Genomics
, vol.6
, pp. 42
-
-
Fox, R.M.1
Von Stetina, S.E.2
Barlow, S.J.3
Shaffer, C.4
Olszewski, K.L.5
Moore, J.H.6
Dupuy, D.7
Vidal, M.8
Miller III, D.M.9
-
76
-
-
0345743610
-
Functional genomics of the nicotinic acetylcholine receptor family of Caenorhabditis elegans
-
Jones, A., Esmaeili, B. and Sattelle, D. (2004) Functional genomics of the nicotinic acetylcholine receptor family of Caenorhabditis elegans. Bioessays, 26, 39-49.
-
(2004)
Bioessays
, vol.26
, pp. 39-49
-
-
Jones, A.1
Esmaeili, B.2
Sattelle, D.3
-
77
-
-
0037122891
-
Regulation of retrograde signaling at neuromuscular junctions by the novel C2 domain protein AEX-1
-
Doi, M. and Iwasaki, K. (2002) Regulation of retrograde signaling at neuromuscular junctions by the novel C2 domain protein AEX-1. Neuron, 33, 249-259.
-
(2002)
Neuron
, vol.33
, pp. 249-259
-
-
Doi, M.1
Iwasaki, K.2
-
78
-
-
0035896035
-
Molecular, genetic and physiological characterization of dystrobrevin-like (dyb-1) mutants of Caenorhabditis elegans
-
Gieseler, K., Mariol, M.C., Bessou, C., Migaud, M., Franks, C.J., Holden-Dye, L. and Segalat, L. (2001) Molecular, genetic and physiological characterization of dystrobrevin-like (dyb-1) mutants of Caenorhabditis elegans. J. Mol. Biol., 307, 107-117.
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 107-117
-
-
Gieseler, K.1
Mariol, M.C.2
Bessou, C.3
Migaud, M.4
Franks, C.J.5
Holden-Dye, L.6
Segalat, L.7
-
79
-
-
0037040583
-
Purkinje cell degeneration (pcd) phenotypes caused by mutations in the axotomy-induced gene, Nna1
-
Fernandez-Gonzalez, A., La Spada, A.R., Treadaway, J., Higdon, J.C., Harris, B.S., Sidman, R.L., Morgan, J.I. and Zuo, J. (2002) Purkinje cell degeneration (pcd) phenotypes caused by mutations in the axotomy-induced gene, Nna1. Science, 295, 1904-1906.
-
(2002)
Science
, vol.295
, pp. 1904-1906
-
-
Fernandez-Gonzalez, A.1
La Spada, A.R.2
Treadaway, J.3
Higdon, J.C.4
Harris, B.S.5
Sidman, R.L.6
Morgan, J.I.7
Zuo, J.8
-
80
-
-
2342652188
-
Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation
-
Nollen, E.A., Garcia, S.M., van Haaften, G., Kim, S., Chavez, A., Morimoto, R.I. and Plasterk, R.H. (2004) Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Proc. Natl Acad. Sci. USA, 101, 6403-6408.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 6403-6408
-
-
Nollen, E.A.1
Garcia, S.M.2
van Haaften, G.3
Kim, S.4
Chavez, A.5
Morimoto, R.I.6
Plasterk, R.H.7
-
81
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
Fernandez-Funez, P., Nino-Rosales, M.L., de Gouyon, B., She, W.C., Luchak, J.M., Martinez, P., Turiegano, E., Benito, J., Capovilla, M., Skinner, P.J. et al. (2000) Identification of genes that modify ataxin-1-induced neurodegeneration. Nature, 408, 101-106.
-
(2000)
Nature
, vol.408
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
de Gouyon, B.3
She, W.C.4
Luchak, J.M.5
Martinez, P.6
Turiegano, E.7
Benito, J.8
Capovilla, M.9
Skinner, P.J.10
-
82
-
-
0034629073
-
Genetic suppression of polyglutamine toxicity in Drosophila
-
Kazemi-Esfarjani, P. and Benzer, S. (2000) Genetic suppression of polyglutamine toxicity in Drosophila. Science, 287, 1837-1840.
-
(2000)
Science
, vol.287
, pp. 1837-1840
-
-
Kazemi-Esfarjani, P.1
Benzer, S.2
-
83
-
-
0345189365
-
Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein
-
Willingham, S., Outeiro, T.F., DeVit, M.J., Lindquist, S.L. and Muchowski, P.J. (2003) Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science, 302, 1769-1772.
-
(2003)
Science
, vol.302
, pp. 1769-1772
-
-
Willingham, S.1
Outeiro, T.F.2
DeVit, M.J.3
Lindquist, S.L.4
Muchowski, P.J.5
-
84
-
-
28844504312
-
Selective sensitivity of Caenorhabditis elegans neurons to RNA interference
-
Asikainen, S., Vartiainen, S., Lakso, M., Nass, R. and Wong, G. (2005) Selective sensitivity of Caenorhabditis elegans neurons to RNA interference. Neuroreport, 16, 1995-1999.
-
(2005)
Neuroreport
, vol.16
, pp. 1995-1999
-
-
Asikainen, S.1
Vartiainen, S.2
Lakso, M.3
Nass, R.4
Wong, G.5
-
85
-
-
0035941485
-
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
-
Timmons, L., Court, D.L. and Fire, A. (2001) Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene, 263, 103-112.
-
(2001)
Gene
, vol.263
, pp. 103-112
-
-
Timmons, L.1
Court, D.L.2
Fire, A.3
-
86
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics, 77, 71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
87
-
-
13144256748
-
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans
-
Pekarsky, Y., Campiglio, M., Siprashvili, Z., Druck, T., Sedkov, Y., Tillib, S., Draganescu, A., Wermuth, P. and Rothman, J.H. (1998) Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans. Proc. Natl Acad. Sci. USA, 95, 8744-8749.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 8744-8749
-
-
Pekarsky, Y.1
Campiglio, M.2
Siprashvili, Z.3
Druck, T.4
Sedkov, Y.5
Tillib, S.6
Draganescu, A.7
Wermuth, P.8
Rothman, J.H.9
-
88
-
-
0038725897
-
Genome-wide RNAi screening in Caenorhabditis elegans
-
Kamath, R.S. and Ahringer, J. (2003) Genome-wide RNAi screening in Caenorhabditis elegans. Methods, 30, 313-321.
-
(2003)
Methods
, vol.30
, pp. 313-321
-
-
Kamath, R.S.1
Ahringer, J.2
-
89
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
Ishihara, T., Hong, M., Zhang, B., Nakagawa, Y., Lee, M.K., Trojanowski, J.Q. and Lee, V.M.Y. (1999) Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron, 24, 751-762.
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
Lee, V.M.Y.7
-
90
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon, M., Zeng, H., Urano, F., Till, J.H., Hubbard, S.R., Harding, H.P., Clark, S.G. and Ron, D. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature, 415, 92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
91
-
-
33646137032
-
CGC C. elegans, Genetic Center - Strain information
-
CGC C. elegans, Genetic Center - strain information.
-
-
-
-
92
-
-
33646153913
-
-
Worm Base
-
Worm Base, http://www.wormbase.org.
-
-
-
-
93
-
-
23444446722
-
The Caenorhabditis elegans gene lin-44 controls the polarity of asymmetric cell divisions
-
Herman, M.A. and Horvitz, H.R. (1994) The Caenorhabditis elegans gene lin-44 controls the polarity of asymmetric cell divisions. Development, 120, 1035-1047.
-
(1994)
Development
, vol.120
, pp. 1035-1047
-
-
Herman, M.A.1
Horvitz, H.R.2
-
94
-
-
0025254082
-
Genetic analysis of defecation in Caenorhabditis elegans
-
Thomas, J.H. (1990) Genetic analysis of defecation in Caenorhabditis elegans. Genetics, 124, 855-872.
-
(1990)
Genetics
, vol.124
, pp. 855-872
-
-
Thomas, J.H.1
-
95
-
-
0037169034
-
RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs
-
Tijsterman, M., Ketting, R.F., Okihara, K.L., Sijen, T. and Plasterk, R.H. (2002) RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs. Science, 295, 694-697.
-
(2002)
Science
, vol.295
, pp. 694-697
-
-
Tijsterman, M.1
Ketting, R.F.2
Okihara, K.L.3
Sijen, T.4
Plasterk, R.H.5
|