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PID: 25108084, Excellent review article discussing the mechanisms of exertional intolerance in HFpEF
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Houstis NE, Lewis GD. Causes of exercise intolerance in heart failure with preserved ejection fraction: searching for consensus. J Card Fail. 2014;20:762–78. Excellent review article discussing the mechanisms of exertional intolerance in HFpEF.
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Houstis, N.E.1
Lewis, G.D.2
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Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction
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COI: 1:CAS:528:DC%2BC2cXptVChsLw%3D, PID: 24658015, This study demonstrates important structural abnormalities within the peripheral skeletal muscles of HFpEF patients including reduced Type I fibers and reduced capillary to fiber ratios, both of which correlated with impaired peak aerobic capacity
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Kitzman DW, Nicklas B, Kraus WE, Lyles MF, Eggebeen J, Morgan TM, et al. Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction. Am J Physiol Heart Circ Physiol. 2014;306:H1364–70. This study demonstrates important structural abnormalities within the peripheral skeletal muscles of HFpEF patients including reduced Type I fibers and reduced capillary to fiber ratios, both of which correlated with impaired peak aerobic capacity.
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Morgan, T.M.6
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PID: 20813282, Important article demonstrating key hemodynamic limitations identified in HFpEF patients
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Borlaug BA, Olson TP, Lam CS, Flood KS, Lerman A, Johnson BD, et al. Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction. J Am Coll Cardiol. 2010;56:845–54. Important article demonstrating key hemodynamic limitations identified in HFpEF patients.
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Borlaug, B.A.1
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Muscle oxygen transport and utilization in heart failure: implications for exercise (in)tolerance
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COI: 1:CAS:528:DC%2BC38XkslCisrw%3D, PID: 22101528, Excellent review article describing impairments in oxygen transport found in heart failure and their implications for exercise intolerance
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Poole DC, Hirai DM, Copp SW, Musch TI. Muscle oxygen transport and utilization in heart failure: implications for exercise (in)tolerance. Am J Physiol Heart Circ Physiol. 2012;302:H1050–63. Excellent review article describing impairments in oxygen transport found in heart failure and their implications for exercise intolerance.
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Poole, D.C.1
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