Identification of the enzymatic mechanism of nitroglycerin bioactivation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 12, 2002, Pages 8306-8311

  Chen, Zhiqiang ^a   Zhang, Jian ^a   Stamler, Jonathan S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE; CARBON 14; CHLORAL HYDRATE; CYANAMIDE; CYCLIC GMP; GLYCERYL TRINITRATE; MITOCHONDRIAL ENZYME; NITRATE; NITRITE; NITROPRUSSIDE SODIUM; OXIDOREDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG INFUSION; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME ASSAY; ENZYME MECHANISM; ENZYME PURIFICATION; METABOLITE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASCULAR RING; VASCULAR SMOOTH MUSCLE;

ALDEHYDE DEHYDROGENASE; ANIMALS; AORTA, THORACIC; BIOTRANSFORMATION; CELL LINE; KINETICS; MACROPHAGES; MICE; MITOCHONDRIA; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NAD; NITROGLYCERIN; RABBITS; VASODILATION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0037062518     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.122225199     Document Type: Article

References (48)