Enhanced vasodilator activity of nitrite in hypertension: Critical role for erythrocytic xanthine oxidoreductase and translational potential

Hypertension

Volumn 61, Issue 5, 2013, Pages 1091-1102

  Ghosh, Suborno M ^a   Kapil, Vikas ^a   Fuentes Calvo, Isabel ^a,b   Bubb, Kristen J ^a   Pearl, Vanessa ^a   Milsom, Alexandra B ^a   Khambata, Rayomand ^a   Maleki Toyserkani, Sheiva ^a   Yousuf, Mubeen ^a   Benjamin, Nigel ^c   Webb, Andrew J ^d   Caulfield, Mark J ^a   Hobbs, Adrian J ^a   Ahluwalia, Amrita ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF SALAMANCA   (Spain)

^c UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

hypertension; nitric oxide; red blood cells; vascular biology

Indexed keywords

ALLOPURINOL; NITRITE REDUCTASE; NITROPRUSSIDE SODIUM; XANTHINE OXIDASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL WALL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ERYTHROCYTE; ESSENTIAL HYPERTENSION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULSE WAVE; RAT; SYSTOLIC BLOOD PRESSURE; VASODILATATION;

ALLOPURINOL; ANIMALS; BLOOD PRESSURE; CROSS-OVER STUDIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ERYTHROCYTES; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; NITRITES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION; TRANSLATIONAL MEDICAL RESEARCH; VASODILATION; XANTHINE DEHYDROGENASE;

EID: 84876688013     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.00933     Document Type: Article

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