Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration

Circulation Research

Volumn 100, Issue 5, 2007, Pages 654-661

  Shiva, Sruti ^a   Huang, Zhi ^a   Grubina, Rozalina ^a   Sun, Junhui ^a   Ringwood, Lorna A ^a   MacArthur, Peter H ^a   Xu, Xiuli ^a   Murphy, Elizabeth ^a   Darley Usmar, Victor M ^c   Gladwin, Mark T ^a,b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Mitochondria; Myoglobin; Nitrite

Indexed keywords

ALLOPURINOL; CYTOCHROME C OXIDASE; DEOXYHEMOGLOBIN; DEOXYMYOGLOBIN; FERRICYANIDE; HEME; MYOGLOBIN; NITRIC OXIDE; NITRITE; NITRITE REDUCTASE; OXYGEN; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART; HEART MITOCHONDRION; HOMOGENATE; IC 50; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; REACTION ANALYSIS; REDUCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY; ANIMAL; BIOSYNTHESIS; CELL RESPIRATION; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; DRUG ANTAGONISM; ENZYMOLOGY; HEART MUSCLE CELL; HORSE; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PH; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CELL RESPIRATION; HEME; HORSES; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MITOCHONDRIA, HEART; MITOCHONDRIA, LIVER; MYOCYTES, CARDIAC; MYOGLOBIN; NITRIC OXIDE; NITRITE REDUCTASES; NITRITES; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33947728687     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000260171.52224.6b     Document Type: Article

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