Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

Nature Medicine

Volumn 9, Issue 12, 2003, Pages 1498-1505

  Cosby, Kenyatta ^a   Partovi, Kristine S ^b   Crawford, Jack H ^c   Patel, Rakesh P ^c   Reiter, Christopher D ^b,d   Martyr, Sabrina ^b,d   Yang, Benjamin K ^b   Waclawiw, Myron A ^a   Zalos, Gloria ^a   Xu, Xiuli ^e   Huang, Kris T ^f   Shields, Howard ^e   Kim Shapiro, Daniel B ^e,f   Schechter, Alan N ^d   Cannon III, Richard O ^a   Gladwin, Mark T ^b,d  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c University of Alabama at Birmingham   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e WAKE FOREST UNIVERSITY   (United States)

^f WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYHEMOGLOBIN; HEMOGLOBIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; NITRITE REDUCTASE; OXYHEMOGLOBIN;

ADULT; ARM BLOOD FLOW; ARTICLE; BRACHIAL ARTERY; CIRCULATION; CONTROLLED STUDY; DEOXYGENATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXERCISE; FEMALE; FOREARM; HUMAN; HUMAN EXPERIMENT; HYPOXIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL; REDUCTION; VASODILATATION;

ADULT; ANIMALS; AORTA, THORACIC; ERYTHROCYTES; FEMALE; HEMOGLOBINS; HUMANS; KINETICS; MALE; MIDDLE AGED; NITRIC OXIDE; NITRITE REDUCTASES; NITRITES; OXIDATION-REDUCTION; RATS; S-NITROSOTHIOLS; VASODILATION;

EID: 10744220361     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm954     Document Type: Article

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