Safety and feasibility of long-term intravenous sodium nitrite infusion in healthy volunteers

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Pluta, Ryszard M ^a   Oldfield, Edward H ^a,b   Bakhtian, Kamran D ^a   Fathi, Ali Reza ^a,c   Smith, René K ^a   DeVroom, Hetty L ^a   Nahavandi, Masoud ^a   Woo, Sukyung ^d   Figg, William D ^d   Lonser, Russell R ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c CANTONAL HOSPITAL AARAU   (Switzerland)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRATE; NITRITE; S NITROSOTHIOL; SODIUM NITRITE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD LEVEL; CLINICAL TRIAL; DRUG DOSE INCREASE; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG INFUSION; DRUG SAFETY; DRUG WITHDRAWAL; ERYTHROCYTE LEVEL; FEASIBILITY STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; LONG TERM CARE; MALE; MAXIMUM TOLERATED DOSE; MEAN ARTERIAL PRESSURE; NATIONAL HEALTH ORGANIZATION; NORMAL HUMAN; SIDE EFFECT; VOLUNTEER; DRUG TOXICITY; HALF LIFE TIME; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; TIME;

ADULT; DRUG TOXICITY; FEASIBILITY STUDIES; FEMALE; HALF-LIFE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; SODIUM NITRITE; TIME FACTORS;

EID: 79251547703     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014504     Document Type: Article

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