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Volumn 14, Issue 1, 2016, Pages

Insulin-like growth factor-1 deficiency and metabolic syndrome

Author keywords

Aging; Cellular protection; Dyslipidemia; GH IGF I axis; Insulin resistance; Lipid metabolism; Mitochondrial dysfunction; Obesity; Oxidative stress

Indexed keywords

CARBOHYDRATE; GROWTH HORMONE; INSULIN; INSULIN RECEPTOR; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

EID: 84955675161     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-015-0762-z     Document Type: Article
Times cited : (223)

References (292)
  • 1
    • 0035897696 scopus 로고    scopus 로고
    • National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III)
    • Executive Summary of The Third Report of The. National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA. 2001;285:2486-97.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 2
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International
    • Alberti KGMM, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WPT, Loria CM, Smith SC. Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International. Circulation. 2009;120:1640-5.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.M.M.1    Eckel, R.H.2    Grundy, S.M.3    Zimmet, P.Z.4    Cleeman, J.I.5    Donato, K.A.6    Fruchart, J.C.7    James, W.P.T.8    Loria, C.M.9    Smith, S.C.10
  • 3
    • 78649444068 scopus 로고    scopus 로고
    • The metabolic syndrome as a predictor of incident diabetes and cardiovascular events in the Health 2000 Study
    • Pajunen P, Rissanen H, Härkänen T, Jula A, Reunanen A, Salomaa V. The metabolic syndrome as a predictor of incident diabetes and cardiovascular events in the Health 2000 Study. Diabetes Metab. 2010;36:395-401.
    • (2010) Diabetes Metab , vol.36 , pp. 395-401
    • Pajunen, P.1    Rissanen, H.2    Härkänen, T.3    Jula, A.4    Reunanen, A.5    Salomaa, V.6
  • 4
    • 0032709705 scopus 로고    scopus 로고
    • Comment on the provisional report from the WHO consultation
    • Balkau B, Charles MA. Comment on the provisional report from the WHO consultation. Diabetic Med. 1999;16:442-3.
    • (1999) Diabetic Med , vol.16 , pp. 442-443
    • Balkau, B.1    Charles, M.A.2
  • 5
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation
    • Alberti KGMM, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med. 1998;15:539-53.
    • (1998) Diabet Med , vol.15 , pp. 539-553
    • Alberti, K.G.M.M.1    Zimmet, P.Z.2
  • 7
    • 38949101433 scopus 로고    scopus 로고
    • The prevalence of the metabolic syndrome and its risk factors in a middle-aged Swedish population-mainly a function of overweight?
    • Hollman G, Kristenson M. The prevalence of the metabolic syndrome and its risk factors in a middle-aged Swedish population-mainly a function of overweight? Eur J Cardiovasc Nurs. 2008;7:21-6.
    • (2008) Eur J Cardiovasc Nurs , vol.7 , pp. 21-26
    • Hollman, G.1    Kristenson, M.2
  • 9
    • 33745099612 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome estimated by International Diabetes Federation criteria in a Hungarian population
    • Császár A, Kékes E, Abel T, Papp R, Kiss I, Balogh S. Prevalence of metabolic syndrome estimated by International Diabetes Federation criteria in a Hungarian population. Blood Press. 2006;15:101-6.
    • (2006) Blood Press , vol.15 , pp. 101-106
    • Császár, A.1    Kékes, E.2    Abel, T.3    Papp, R.4    Kiss, I.5    Balogh, S.6
  • 10
    • 33847193580 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome using WHO, ATPIII and IDF definitions in Asian Indians: the Chennai Urban Rural Epidemiology Study (CURES-34)
    • Deepa M, Farooq S, Datta M, Deepa R, Mohan V. Prevalence of metabolic syndrome using WHO, ATPIII and IDF definitions in Asian Indians: the Chennai Urban Rural Epidemiology Study (CURES-34). Diabetes Metab Res Rev. 2007;23:127-34.
    • (2007) Diabetes Metab Res Rev , vol.23 , pp. 127-134
    • Deepa, M.1    Farooq, S.2    Datta, M.3    Deepa, R.4    Mohan, V.5
  • 11
    • 34248633732 scopus 로고    scopus 로고
    • Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease. A population-based study
    • Jeppesen J, Hansen TW, Rasmussen S, Ibsen H, Torp-Pedersen C, Madsbad S. Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease. A population-based study. J Am Coll Cardiol. 2007;49:2112-9.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2112-2119
    • Jeppesen, J.1    Hansen, T.W.2    Rasmussen, S.3    Ibsen, H.4    Torp-Pedersen, C.5    Madsbad, S.6
  • 13
    • 33645355105 scopus 로고    scopus 로고
    • The metabolic syndrome in an Arab population: a first look at the new International Diabetes Federation criteria
    • Harzallah F, Alberti H, Ben Khalifa F. The metabolic syndrome in an Arab population: a first look at the new International Diabetes Federation criteria. Diabet Med. 2006;23:441-4.
    • (2006) Diabet Med , vol.23 , pp. 441-444
    • Harzallah, F.1    Alberti, H.2    Ben Khalifa, F.3
  • 14
    • 38549160615 scopus 로고    scopus 로고
    • Prevalence, agreement and classification of various metabolic syndrome criteria among ethnic Chinese: a report on the hospital-based health diagnosis of the adult population
    • Chien KL, Lee BC, Hsu HC, Lin HJ, Chen MF, Lee YT. Prevalence, agreement and classification of various metabolic syndrome criteria among ethnic Chinese: a report on the hospital-based health diagnosis of the adult population. Atherosclerosis. 2008;196:764-71.
    • (2008) Atherosclerosis , vol.196 , pp. 764-771
    • Chien, K.L.1    Lee, B.C.2    Hsu, H.C.3    Lin, H.J.4    Chen, M.F.5    Lee, Y.T.6
  • 15
    • 34247615019 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome in Iranian adult population, concordance between the IDF with the ATPIII and the WHO definitions
    • Zabetian A, Hadaegh F, Azizi F. Prevalence of metabolic syndrome in Iranian adult population, concordance between the IDF with the ATPIII and the WHO definitions. Diabetes Res Clin Pract. 2007;77:251-7.
    • (2007) Diabetes Res Clin Pract , vol.77 , pp. 251-257
    • Zabetian, A.1    Hadaegh, F.2    Azizi, F.3
  • 18
    • 33645467024 scopus 로고    scopus 로고
    • Characteristics and prevalence of the metabolic syndrome among three ethnic groups in Canada
    • Liu J, Hanley AJG, Young TK, Harris SB, Zinman B. Characteristics and prevalence of the metabolic syndrome among three ethnic groups in Canada. Int J Obes (Lond). 2006;30:669-76.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 669-676
    • Liu, J.1    Hanley, A.J.G.2    Young, T.K.3    Harris, S.B.4    Zinman, B.5
  • 24
    • 2142687587 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome among Filipino adults aged 20 years and over
    • Tanchoco CC, Cruz AJ, Duante CA, Litonjua AD. Prevalence of metabolic syndrome among Filipino adults aged 20 years and over. Asia Pac J Clin Nutr. 2003;12:271-6.
    • (2003) Asia Pac J Clin Nutr , vol.12 , pp. 271-276
    • Tanchoco, C.C.1    Cruz, A.J.2    Duante, C.A.3    Litonjua, A.D.4
  • 28
    • 30544433479 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome defined by the international diabetes federation among adults in the U.S
    • Ford ES. Prevalence of the metabolic syndrome defined by the international diabetes federation among adults in the U.S. Diabetes Care. 2005;28:2745-9.
    • (2005) Diabetes Care , vol.28 , pp. 2745-2749
    • Ford, E.S.1
  • 29
    • 33748502537 scopus 로고    scopus 로고
    • Prevalence of obesity and metabolic syndrome in Taiwan
    • Hwang L-C, Bai C-H, Chen C-J. Prevalence of obesity and metabolic syndrome in Taiwan. J Formos Med Assoc. 2006;105:626-35.
    • (2006) J Formos Med Assoc , vol.105 , pp. 626-635
    • Hwang, L.-C.1    Bai, C.-H.2    Chen, C.-J.3
  • 30
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey
    • Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287:356-9.
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 31
    • 0038566287 scopus 로고    scopus 로고
    • A comparison of the prevalence of the metabolic syndrome using two proposed definitions
    • Ford ES, Giles WH. A comparison of the prevalence of the metabolic syndrome using two proposed definitions. Diabetes Care. 2003;26:575-81.
    • (2003) Diabetes Care , vol.26 , pp. 575-581
    • Ford, E.S.1    Giles, W.H.2
  • 32
    • 0037463608 scopus 로고    scopus 로고
    • The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
    • Park Y-W, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB. The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch Intern Med. 2003;163:427-36.
    • (2003) Arch Intern Med , vol.163 , pp. 427-436
    • Park, Y.-W.1    Zhu, S.2    Palaniappan, L.3    Heshka, S.4    Carnethon, M.R.5    Heymsfield, S.B.6
  • 33
    • 4644279733 scopus 로고    scopus 로고
    • Increasing prevalence of the metabolic syndrome among US adults
    • Ford ES, Giles WH, Mokdad AH. Increasing prevalence of the metabolic syndrome among US adults. Diabetes Care. 2004;27:2444-9.
    • (2004) Diabetes Care , vol.27 , pp. 2444-2449
    • Ford, E.S.1    Giles, W.H.2    Mokdad, A.H.3
  • 34
    • 33847013719 scopus 로고    scopus 로고
    • Features of metabolic syndrome in non-diabetic Italians and Brazilians: a discriminant analysis
    • Leite MLC, Nicolosi A, Firmo JOA, Lima-Costa MF. Features of metabolic syndrome in non-diabetic Italians and Brazilians: a discriminant analysis. Int J Clin Pract. 2007;61:32-8.
    • (2007) Int J Clin Pract , vol.61 , pp. 32-38
    • Leite, M.L.C.1    Nicolosi, A.2    Firmo, J.O.A.3    Lima-Costa, M.F.4
  • 43
    • 0346962890 scopus 로고    scopus 로고
    • The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)
    • Girman CJ, Rhodes T, Mercuri M, Pyörälä K, Kjekshus J, Pedersen TR, Beere PA, Gotto AM, Clearfield M. The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). Am J Cardiol. 2004;93:136-41.
    • (2004) Am J Cardiol , vol.93 , pp. 136-141
    • Girman, C.J.1    Rhodes, T.2    Mercuri, M.3    Pyörälä, K.4    Kjekshus, J.5    Pedersen, T.R.6    Beere, P.A.7    Gotto, A.M.8    Clearfield, M.9
  • 44
    • 4444222221 scopus 로고    scopus 로고
    • Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
    • Malik S, Wong ND, Franklin SS, Kamath TV, L'Italien GJ, Pio JR, Williams GR. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation. 2004;110:1245-50.
    • (2004) Circulation , vol.110 , pp. 1245-1250
    • Malik, S.1    Wong, N.D.2    Franklin, S.S.3    Kamath, T.V.4    L'Italien, G.J.5    Pio, J.R.6    Williams, G.R.7
  • 45
    • 1542286084 scopus 로고    scopus 로고
    • The metabolic syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm
    • Olijhoek JK, van der Graaf Y, Banga J-D, Algra A, Rabelink TJ, Visseren FLJ. The metabolic syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm. Eur Heart J. 2004;25:342-8.
    • (2004) Eur Heart J , vol.25 , pp. 342-348
    • Olijhoek, J.K.1    Graaf, Y.2    Banga, J.-D.3    Algra, A.4    Rabelink, T.J.5    Visseren, F.L.J.6
  • 46
    • 0037407403 scopus 로고    scopus 로고
    • NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older
    • Alexander CM, Landsman PB, Teutsch SM, Haffner SM. NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Diabetes. 2003;52:1210-4.
    • (2003) Diabetes , vol.52 , pp. 1210-1214
    • Alexander, C.M.1    Landsman, P.B.2    Teutsch, S.M.3    Haffner, S.M.4
  • 47
    • 0347716449 scopus 로고    scopus 로고
    • Association of the metabolic syndrome with History of Myocardial Infarction and Stroke in the Third National Health and Nutrition Examination Survey
    • Ninomiya JK, L'Italien G, Criqui MH, Whyte JL, Gamst A, Chen RS. Association of the metabolic syndrome with History of Myocardial Infarction and Stroke in the Third National Health and Nutrition Examination Survey. Circulation. 2004;109:42-6.
    • (2004) Circulation , vol.109 , pp. 42-46
    • Ninomiya, J.K.1    L'Italien, G.2    Criqui, M.H.3    Whyte, J.L.4    Gamst, A.5    Chen, R.S.6
  • 50
    • 14044253546 scopus 로고    scopus 로고
    • High prevalence of metabolic syndrome among young women with premature coronary artery disease
    • Turhan H, Yasar AS, Basar N, Bicer A, Erbay AR, Yetkin E. High prevalence of metabolic syndrome among young women with premature coronary artery disease. Coron Artery Dis. 2005;16:37-40.
    • (2005) Coron Artery Dis , vol.16 , pp. 37-40
    • Turhan, H.1    Yasar, A.S.2    Basar, N.3    Bicer, A.4    Erbay, A.R.5    Yetkin, E.6
  • 52
    • 28944434431 scopus 로고    scopus 로고
    • Metabolic syndrome vs Framingham risk score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus
    • Wannamethee SG, Shaper AG, Lennon L, Morris RW. Metabolic syndrome vs Framingham risk score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus. Arch Intern Med. 2005;165:2644-50.
    • (2005) Arch Intern Med , vol.165 , pp. 2644-2650
    • Wannamethee, S.G.1    Shaper, A.G.2    Lennon, L.3    Morris, R.W.4
  • 53
    • 34347255382 scopus 로고    scopus 로고
    • Metabolic syndrome, its preeminent clusters, incident coronary heart disease and all-cause mortality-results of prospective analysis for the Atherosclerosis Risk in Communities study
    • Hong Y, Jin X, Mo J, Lin H-M, Duan Y, Pu M, Wolbrette DL, Liao D. Metabolic syndrome, its preeminent clusters, incident coronary heart disease and all-cause mortality-results of prospective analysis for the Atherosclerosis Risk in Communities study. J Intern Med. 2007;262:113-22.
    • (2007) J Intern Med , vol.262 , pp. 113-122
    • Hong, Y.1    Jin, X.2    Mo, J.3    Lin, H.-M.4    Duan, Y.5    Pu, M.6    Wolbrette, D.L.7    Liao, D.8
  • 54
    • 34247603049 scopus 로고    scopus 로고
    • Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome
    • Meigs JB, Rutter MK, Sullivan LM, Fox CS, D'Agostino RB, Wilson PWF. Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome. Diabetes Care. 2007;30:1219-25.
    • (2007) Diabetes Care , vol.30 , pp. 1219-1225
    • Meigs, J.B.1    Rutter, M.K.2    Sullivan, L.M.3    Fox, C.S.4    D'Agostino, R.B.5    Wilson, P.W.F.6
  • 55
    • 2442647863 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women
    • Hu G, Qiao Q, Tuomilehto J, Balkau B, Borch-Johnsen K, Pyorala K. Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch Intern Med. 2004;164:1066-76.
    • (2004) Arch Intern Med , vol.164 , pp. 1066-1076
    • Hu, G.1    Qiao, Q.2    Tuomilehto, J.3    Balkau, B.4    Borch-Johnsen, K.5    Pyorala, K.6
  • 57
    • 0032474246 scopus 로고    scopus 로고
    • Not all fat is alike
    • Arner P. Not all fat is alike. Lancet. 1998;351:1301-2.
    • (1998) Lancet , vol.351 , pp. 1301-1302
    • Arner, P.1
  • 58
    • 0031647224 scopus 로고    scopus 로고
    • Regulation of lipolysis in humans. Pathophysiological modulation in obesity, diabetes, and hyperlipidaemia
    • Large V, Arner P. Regulation of lipolysis in humans. Pathophysiological modulation in obesity, diabetes, and hyperlipidaemia. Diabetes Metab. 1998;24:409-18.
    • (1998) Diabetes Metab , vol.24 , pp. 409-418
    • Large, V.1    Arner, P.2
  • 59
    • 33846829811 scopus 로고    scopus 로고
    • Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk
    • (discussion S29-32)
    • Bergman RN, Kim SP, Hsu IR, Catalano KJ, Chiu JD, Kabir M, Richey JM, Ader M: Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. Am J Med. 2007;120(2 suppl 1):S3-S8 (discussion S29-32).
    • (2007) Am J Med , vol.120 , Issue.2 , pp. S3-S8
    • Bergman, R.N.1    Kim, S.P.2    Hsu, I.R.3    Catalano, K.J.4    Chiu, J.D.5    Kabir, M.6    Richey, J.M.7    Ader, M.8
  • 60
    • 37549022688 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • de Luca C, Olefsky JM. Inflammation and insulin resistance. FEBS Lett. 2008;582:97-105.
    • (2008) FEBS Lett , vol.582 , pp. 97-105
    • de Luca, C.1    Olefsky, J.M.2
  • 61
    • 0036783236 scopus 로고    scopus 로고
    • Components of the metabolic syndrome and risk of cardiovascular disease and diabetes in Beaver Dam
    • Klein BEK, Klein R, Lee KE. Components of the metabolic syndrome and risk of cardiovascular disease and diabetes in Beaver Dam. Diabetes Care. 2002;25:1790-4.
    • (2002) Diabetes Care , vol.25 , pp. 1790-1794
    • Klein, B.E.K.1    Klein, R.2    Lee, K.E.3
  • 63
    • 0036891935 scopus 로고    scopus 로고
    • Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study
    • Laaksonen DE, Lakka H-M, Niskanen LK, Kaplan GA, Salonen JT, Lakka TA. Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. Am J Epidemiol. 2002;156:1070-7.
    • (2002) Am J Epidemiol , vol.156 , pp. 1070-1077
    • Laaksonen, D.E.1    Lakka, H.-M.2    Niskanen, L.K.3    Kaplan, G.A.4    Salonen, J.T.5    Lakka, T.A.6
  • 64
    • 0036787485 scopus 로고    scopus 로고
    • Components of the "metabolic syndrome" and incidence of type 2 diabetes
    • Hanson RL, Imperatore G, Bennett PH, Knowler WC. Components of the "metabolic syndrome" and incidence of type 2 diabetes. Diabetes. 2002;51:3120-7.
    • (2002) Diabetes , vol.51 , pp. 3120-3127
    • Hanson, R.L.1    Imperatore, G.2    Bennett, P.H.3    Knowler, W.C.4
  • 65
    • 0032877903 scopus 로고    scopus 로고
    • Type 2 diabetes: an overview
    • Lebovitz HE. Type 2 diabetes: an overview. Clin Chem. 1999;45(8 Pt 2):1339-45.
    • (1999) Clin Chem , vol.45 , Issue.8 , pp. 1339-1345
    • Lebovitz, H.E.1
  • 66
    • 33644898538 scopus 로고    scopus 로고
    • Metabolic syndrome: Connecting and reconciling cardiovascular and diabetes worlds
    • Grundy SM. Metabolic syndrome: Connecting and reconciling cardiovascular and diabetes worlds. J Am Coll Cardiol. 2006;47:1093-100.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1093-1100
    • Grundy, S.M.1
  • 67
    • 53049108337 scopus 로고    scopus 로고
    • Metabolic syndrome and incident diabetes
    • Ford ES, Li C, Sattar N. Metabolic syndrome and incident diabetes. Diabetes Care. 2008;31:1898-904.
    • (2008) Diabetes Care , vol.31 , pp. 1898-1904
    • Ford, E.S.1    Li, C.2    Sattar, N.3
  • 70
    • 34548499677 scopus 로고    scopus 로고
    • Relationship of metabolic syndrome and obstructive sleep apnea
    • Parish JM, Adam T, Facchiano L. Relationship of metabolic syndrome and obstructive sleep apnea. J Clin Sleep Med. 2007;3:467-72.
    • (2007) J Clin Sleep Med , vol.3 , pp. 467-472
    • Parish, J.M.1    Adam, T.2    Facchiano, L.3
  • 71
    • 2442419626 scopus 로고    scopus 로고
    • Obstructive sleep apnoea, metabolic syndrome, and cardiovascular outcomes
    • Gami AS, Somers VK. Obstructive sleep apnoea, metabolic syndrome, and cardiovascular outcomes. Eur Heart J. 2004;25:709-11.
    • (2004) Eur Heart J , vol.25 , pp. 709-711
    • Gami, A.S.1    Somers, V.K.2
  • 72
    • 33751253095 scopus 로고    scopus 로고
    • Obstructive sleep apnoea is independently associated with the metabolic syndrome but not insulin resistance state
    • Gruber A, Horwood F, Sithole J, Ali NJ, Idris I. Obstructive sleep apnoea is independently associated with the metabolic syndrome but not insulin resistance state. Cardiovasc Diabetol. 2006;5:22.
    • (2006) Cardiovasc Diabetol , vol.5 , pp. 22
    • Gruber, A.1    Horwood, F.2    Sithole, J.3    Ali, N.J.4    Idris, I.5
  • 73
    • 0036499729 scopus 로고    scopus 로고
    • Sleep-disordered breathing and the current epidemic of obesity: consequence or contributing factor?
    • Tasali E, Van Cauter E. Sleep-disordered breathing and the current epidemic of obesity: consequence or contributing factor? Am J Respir Crit Care Med. 2002;165:562-3.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 562-563
    • Tasali, E.1    Cauter, E.2
  • 74
    • 26444439215 scopus 로고    scopus 로고
    • A link between short sleep and obesity: building the evidence for causation
    • Cizza G, Skarulis M, Mignot E. A link between short sleep and obesity: building the evidence for causation. Sleep. 2005;28:1217-20.
    • (2005) Sleep , vol.28 , pp. 1217-1220
    • Cizza, G.1    Skarulis, M.2    Mignot, E.3
  • 75
    • 18844378616 scopus 로고    scopus 로고
    • Sleep apnea is a manifestation of the metabolic syndrome
    • Vgontzas AN, Bixler EO, Chrousos GP. Sleep apnea is a manifestation of the metabolic syndrome. Sleep Med Rev. 2005;9:211-24.
    • (2005) Sleep Med Rev , vol.9 , pp. 211-224
    • Vgontzas, A.N.1    Bixler, E.O.2    Chrousos, G.P.3
  • 76
    • 33846233354 scopus 로고    scopus 로고
    • Sleep and the metabolic syndrome
    • Wolk R, Somers VK. Sleep and the metabolic syndrome. Exp Physiol. 2007;92:67-78.
    • (2007) Exp Physiol , vol.92 , pp. 67-78
    • Wolk, R.1    Somers, V.K.2
  • 78
    • 33846626478 scopus 로고    scopus 로고
    • The prevalence of retinopathy in impaired glucose tolerance and recent-onset diabetes in the Diabetes Prevention Program
    • The prevalence of retinopathy in impaired glucose tolerance and recent-onset diabetes in the Diabetes Prevention Program. Diabet Med. 2007;24:137-44.
    • (2007) Diabet Med , vol.24 , pp. 137-144
  • 79
    • 47949104275 scopus 로고    scopus 로고
    • Retinopathy in subjects with impaired fasting glucose: the NANSY-Eye baseline report
    • Tyrberg M, Melander A, Lövestam-Adrian M, Lindblad U. Retinopathy in subjects with impaired fasting glucose: the NANSY-Eye baseline report. Diabetes Obes Metab. 2008;10:646-51.
    • (2008) Diabetes Obes Metab , vol.10 , pp. 646-651
    • Tyrberg, M.1    Melander, A.2    Lövestam-Adrian, M.3    Lindblad, U.4
  • 80
    • 34548815937 scopus 로고    scopus 로고
    • Are patients who have metabolic syndrome without diabetes at risk for developing chronic kidney disease? Evidence based on data from a large cohort screening population
    • Rashidi A, Ghanbarian A, Azizi F. Are patients who have metabolic syndrome without diabetes at risk for developing chronic kidney disease? Evidence based on data from a large cohort screening population. Clin J Am Soc Nephrol. 2007;2:976-83.
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 976-983
    • Rashidi, A.1    Ghanbarian, A.2    Azizi, F.3
  • 81
    • 27444433127 scopus 로고    scopus 로고
    • Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults
    • Kurella M, Lo JC, Chertow GM. Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults. J Am Soc Nephrol. 2005;16:2134-40.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2134-2140
    • Kurella, M.1    Lo, J.C.2    Chertow, G.M.3
  • 83
    • 34548644370 scopus 로고    scopus 로고
    • The association between metabolic syndrome, microalbuminuria and impaired renal function in the general population: impact on cardiovascular disease and mortality
    • Klausen KP, Parving H-H, Scharling H, Jensen JS. The association between metabolic syndrome, microalbuminuria and impaired renal function in the general population: impact on cardiovascular disease and mortality. J Intern Med. 2007;262:470-8.
    • (2007) J Intern Med , vol.262 , pp. 470-478
    • Klausen, K.P.1    Parving, H.-H.2    Scharling, H.3    Jensen, J.S.4
  • 84
    • 34748916462 scopus 로고    scopus 로고
    • Microalbuminuria and the metabolic syndrome and its components in the Chinese population
    • Lin C-C, Liu C-S, Li T-C, Chen C-C, Li C-I, Lin W-Y. Microalbuminuria and the metabolic syndrome and its components in the Chinese population. Eur J Clin Invest. 2007;37:783-90.
    • (2007) Eur J Clin Invest , vol.37 , pp. 783-790
    • Lin, C.-C.1    Liu, C.-S.2    Li, T.-C.3    Chen, C.-C.4    Li, C.-I.5    Lin, W.-Y.6
  • 86
    • 33644542482 scopus 로고    scopus 로고
    • Idiopathic neuropathy, prediabetes and the metabolic syndrome
    • Gordon Smith A, Robinson Singleton J. Idiopathic neuropathy, prediabetes and the metabolic syndrome. J Neurol Sci. 2006;242(1-2 SPEC. ISS.):9-14.
    • (2006) J Neurol Sci , vol.242 , Issue.1-2 , pp. 9-14
    • Gordon Smith, A.1    Robinson Singleton, J.2
  • 88
    • 0018184054 scopus 로고
    • The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin
    • Rinderknecht E, Humbel RE. The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J Biol Chem. 1978;253:2769-76.
    • (1978) J Biol Chem , vol.253 , pp. 2769-2776
    • Rinderknecht, E.1    Humbel, R.E.2
  • 89
    • 0019504036 scopus 로고
    • Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary
    • Berelowitz M, Szabo M, Frohman LA, Firestone S, Chu L, Hintz RL. Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary. Science. 1981;212:1279-81.
    • (1981) Science , vol.212 , pp. 1279-1281
    • Berelowitz, M.1    Szabo, M.2    Frohman, L.A.3    Firestone, S.4    Chu, L.5    Hintz, R.L.6
  • 91
    • 0025820192 scopus 로고
    • Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes
    • Böni-Schnetzler M, Schmid C, Meier PJ, Froesch ER. Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. Am J Physiol. 1991;260:E846-51.
    • (1991) Am J Physiol , vol.260 , pp. E846-E851
    • Böni-Schnetzler, M.1    Schmid, C.2    Meier, P.J.3    Froesch, E.R.4
  • 92
    • 0005096726 scopus 로고
    • Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action
    • D'Ercole AJ, Stiles AD, Underwood LE. Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci USA. 1984;81:935-9.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 935-939
    • D'Ercole, A.J.1    Stiles, A.D.2    Underwood, L.E.3
  • 93
    • 0032565746 scopus 로고    scopus 로고
    • Role of insulin-like growth factor binding proteins in controlling IGF actions
    • Clemmons DR. Role of insulin-like growth factor binding proteins in controlling IGF actions. Mol Cell Endocrinol. 1998;140:19-24.
    • (1998) Mol Cell Endocrinol , vol.140 , pp. 19-24
    • Clemmons, D.R.1
  • 96
    • 0036166389 scopus 로고    scopus 로고
    • Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells
    • Liu J, Kosma V-M, Vänttinen T, Hydén-Granskog C, Voutilainen R. Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells. Mol Hum Reprod. 2002;8:136-41.
    • (2002) Mol Hum Reprod , vol.8 , pp. 136-141
    • Liu, J.1    Kosma, V.-M.2    Vänttinen, T.3    Hydén-Granskog, C.4    Voutilainen, R.5
  • 97
    • 0037622754 scopus 로고    scopus 로고
    • Generation of anti-insulin-like growth factor-binding protein-related protein 1 (IGFBP-rP1/MAC25) monoclonal antibodies and immunoassay: quantification of IGFBP-rP1 in human serum and distribution in human fluids and tissues
    • López-Bermejo A, Khosravi J, Corless CL, Krishna RG, Diamandi A, Bodani U, Kofoed EM, Graham DL, Hwa V, Rosenfeld RG. Generation of anti-insulin-like growth factor-binding protein-related protein 1 (IGFBP-rP1/MAC25) monoclonal antibodies and immunoassay: quantification of IGFBP-rP1 in human serum and distribution in human fluids and tissues. J Clin Endocrinol Metab. 2003;88:3401-8.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3401-3408
    • López-Bermejo, A.1    Khosravi, J.2    Corless, C.L.3    Krishna, R.G.4    Diamandi, A.5    Bodani, U.6    Kofoed, E.M.7    Graham, D.L.8    Hwa, V.9    Rosenfeld, R.G.10
  • 99
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith D, Werner H, Beitner-Johnson D, Roberts CT. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev. 1995;16:143-63.
    • (1995) Endocr Rev , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts, C.T.4
  • 100
    • 0036550234 scopus 로고    scopus 로고
    • Signalling through IGF-I and insulin receptors: where is the specificity?
    • Kim JJ, Accili D. Signalling through IGF-I and insulin receptors: where is the specificity? Growth Horm IGF Res. 2002;12:84-90.
    • (2002) Growth Horm IGF Res , vol.12 , pp. 84-90
    • Kim, J.J.1    Accili, D.2
  • 101
    • 79960654127 scopus 로고    scopus 로고
    • Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats
    • Garcia-Fernandez M, Sierra I, Puche JE, Guerra L, Castilla-Cortazar I. Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats. J Transl Med. 2011;9:123.
    • (2011) J Transl Med , vol.9 , pp. 123
    • Garcia-Fernandez, M.1    Sierra, I.2    Puche, J.E.3    Guerra, L.4    Castilla-Cortazar, I.5
  • 103
    • 0032453535 scopus 로고    scopus 로고
    • What is the function of IGF-II in postnatal life? Answers from transgenic mouse models
    • Wolf E, Hoeflich A, Lahm H. What is the function of IGF-II in postnatal life? Answers from transgenic mouse models. Growth Horm IGF Res. 1998;8:185-93.
    • (1998) Growth Horm IGF Res , vol.8 , pp. 185-193
    • Wolf, E.1    Hoeflich, A.2    Lahm, H.3
  • 107
    • 42449105754 scopus 로고    scopus 로고
    • Low doses of insulin-like growth factor I improve insulin resistance, lipid metabolism, and oxidative damage in aging rats
    • García-Fernández M, Delgado G, Puche JE, González-Barón S, Cortázar IC. Low doses of insulin-like growth factor I improve insulin resistance, lipid metabolism, and oxidative damage in aging rats. Endocrinology. 2008;149:2433-42.
    • (2008) Endocrinology , vol.149 , pp. 2433-2442
    • García-Fernández, M.1    Delgado, G.2    Puche, J.E.3    González-Barón, S.4    Cortázar, I.C.5
  • 117
    • 8744259926 scopus 로고    scopus 로고
    • Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance
    • Zick Y. Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance. Biochem Soc Trans. 2004;32(Pt 5):812-6.
    • (2004) Biochem Soc Trans , vol.32 , pp. 812-816
    • Zick, Y.1
  • 118
  • 119
    • 34248180625 scopus 로고    scopus 로고
    • Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors
    • Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT. Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors. Mol Cell Biol. 2007;27:3569-77.
    • (2007) Mol Cell Biol , vol.27 , pp. 3569-3577
    • Denley, A.1    Carroll, J.M.2    Brierley, G.V.3    Cosgrove, L.4    Wallace, J.5    Forbes, B.6    Roberts, C.T.7
  • 120
    • 84903535463 scopus 로고    scopus 로고
    • Insulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3β to regulate aerobic glycolysis
    • Landis J, Shaw LM. Insulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3β to regulate aerobic glycolysis. J Biol Chem. 2014;289:18603-13.
    • (2014) J Biol Chem , vol.289 , pp. 18603-18613
    • Landis, J.1    Shaw, L.M.2
  • 121
    • 63049091804 scopus 로고    scopus 로고
    • The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2
    • Hanke S, Mann M. The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2. Mol Cell Proteomics. 2009;8:519-34.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 519-534
    • Hanke, S.1    Mann, M.2
  • 122
    • 67349210392 scopus 로고    scopus 로고
    • Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis
    • Kim B, Feldman EL. Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis. Apoptosis. 2009;14:665-73.
    • (2009) Apoptosis , vol.14 , pp. 665-673
    • Kim, B.1    Feldman, E.L.2
  • 123
    • 84868706059 scopus 로고    scopus 로고
    • Human conditions of insulin-like growth factor-I (IGF-I) deficiency
    • Puche JE, Castilla-Cortázar I. Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med. 2012;10:224.
    • (2012) J Transl Med , vol.10 , pp. 224
    • Puche, J.E.1    Castilla-Cortázar, I.2
  • 124
    • 77952349493 scopus 로고    scopus 로고
    • Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?
    • Smith TJ. Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases? Pharmacol Rev. 2010;62:199-236.
    • (2010) Pharmacol Rev , vol.62 , pp. 199-236
    • Smith, T.J.1
  • 125
    • 47149096915 scopus 로고    scopus 로고
    • Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity
    • Heilbronn LK, Campbell LV. Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity. Curr Pharm Des. 2008;14:1225-30.
    • (2008) Curr Pharm Des , vol.14 , pp. 1225-1230
    • Heilbronn, L.K.1    Campbell, L.V.2
  • 126
    • 44249095380 scopus 로고    scopus 로고
    • Implications of cross-talk between tumour necrosis factor and insulin-like growth factor-1 signalling in skeletal muscle
    • Grounds MD, Radley HG, Gebski BL, Bogoyevitch MA, Shavlakadze T. Implications of cross-talk between tumour necrosis factor and insulin-like growth factor-1 signalling in skeletal muscle. Clin Exp Pharmacol Physiol. 2008;35:846-51.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 846-851
    • Grounds, M.D.1    Radley, H.G.2    Gebski, B.L.3    Bogoyevitch, M.A.4    Shavlakadze, T.5
  • 127
    • 41849117809 scopus 로고    scopus 로고
    • Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology
    • O'Connor JC, McCusker RH, Strle K, Johnson RW, Dantzer R, Kelley KW. Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology. Cell Immunol. 2008;252:91-110.
    • (2008) Cell Immunol , vol.252 , pp. 91-110
    • O'Connor, J.C.1    McCusker, R.H.2    Strle, K.3    Johnson, R.W.4    Dantzer, R.5    Kelley, K.W.6
  • 128
    • 0020307531 scopus 로고
    • Insulin-like growth factors in the fed and fasted states
    • Merimee TJ, Zapf J, Froesch ER. Insulin-like growth factors in the fed and fasted states. J Clin Endocrinol Metab. 1982;55:999-1002.
    • (1982) J Clin Endocrinol Metab , vol.55 , pp. 999-1002
    • Merimee, T.J.1    Zapf, J.2    Froesch, E.R.3
  • 129
    • 33751059804 scopus 로고    scopus 로고
    • Involvement of insulin-like growth factor-I in the control of glucose homeostasis
    • Clemmons DR. Involvement of insulin-like growth factor-I in the control of glucose homeostasis. Curr Opin Pharmacol. 2006;6:620-5.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 620-625
    • Clemmons, D.R.1
  • 130
  • 131
    • 0026694394 scopus 로고
    • Expression of hepatic insulin-like growth factor-I and insulin-like growth factor-binding protein-1 genes is transcriptionally regulated in streptozotocin-diabetic rats
    • Pao CI, Farmer PK, Begovic S, Goldstein S, Wu GJ, Phillips LS. Expression of hepatic insulin-like growth factor-I and insulin-like growth factor-binding protein-1 genes is transcriptionally regulated in streptozotocin-diabetic rats. Mol Endocrinol. 1992;6:969-77.
    • (1992) Mol Endocrinol , vol.6 , pp. 969-977
    • Pao, C.I.1    Farmer, P.K.2    Begovic, S.3    Goldstein, S.4    Wu, G.J.5    Phillips, L.S.6
  • 134
    • 0028937491 scopus 로고
    • Recombinant human insulin-like growth factor-I enhances whole body protein anabolism and significantly diminishes the protein catabolic effects of prednisone in humans without a diabetogenic effect
    • Mauras N, Beaufrere B. Recombinant human insulin-like growth factor-I enhances whole body protein anabolism and significantly diminishes the protein catabolic effects of prednisone in humans without a diabetogenic effect. J Clin Endocrinol Metab. 1995;80:869-74.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 869-874
    • Mauras, N.1    Beaufrere, B.2
  • 135
    • 13544273450 scopus 로고    scopus 로고
    • Are the metabolic effects of GH and IGF-I separable?
    • Mauras N, Haymond MW. Are the metabolic effects of GH and IGF-I separable? Growth Horm IGF Res. 2005;15:19-27.
    • (2005) Growth Horm IGF Res , vol.15 , pp. 19-27
    • Mauras, N.1    Haymond, M.W.2
  • 136
    • 84922164184 scopus 로고    scopus 로고
    • The insulin-like growth factor I system: physiological and pathophysiological implication in cardiovascular diseases associated with metabolic syndrome
    • Ren J, Anversa P. The insulin-like growth factor I system: physiological and pathophysiological implication in cardiovascular diseases associated with metabolic syndrome. Biochem Pharmacol 2015;93:409-17.
    • (2015) Biochem Pharmacol , vol.93 , pp. 409-417
    • Ren, J.1    Anversa, P.2
  • 137
    • 0027361099 scopus 로고
    • Comparison of the effects of recombinant human insulin-like growth factor-I and insulin on glucose and leucine kinetics in humans
    • Laager R, Ninnis R, Keller U. Comparison of the effects of recombinant human insulin-like growth factor-I and insulin on glucose and leucine kinetics in humans. J Clin Invest. 1993;92:1903-9.
    • (1993) J Clin Invest , vol.92 , pp. 1903-1909
    • Laager, R.1    Ninnis, R.2    Keller, U.3
  • 140
    • 0028223994 scopus 로고
    • Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults
    • Boulware SD, Tamborlane WV, Rennert NJ, Gesundheit N, Sherwin RS. Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults. J Clin Invest. 1994;93:1131-9.
    • (1994) J Clin Invest , vol.93 , pp. 1131-1139
    • Boulware, S.D.1    Tamborlane, W.V.2    Rennert, N.J.3    Gesundheit, N.4    Sherwin, R.S.5
  • 141
    • 0030921226 scopus 로고    scopus 로고
    • The effect of oral glucose on serum free insulin-like growth factor-I and -II in health adults
    • Frystyk J, Grøfte T, Skjaerbaek C, Orskov H. The effect of oral glucose on serum free insulin-like growth factor-I and -II in health adults. J Clin Endocrinol Metab. 1997;82:3124-7.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3124-3127
    • Frystyk, J.1    Grøfte, T.2    Skjaerbaek, C.3    Orskov, H.4
  • 142
    • 0037134529 scopus 로고    scopus 로고
    • Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture
    • Sakai K, Lowman HB, Clemmons DR. Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture. J Biol Chem. 2002;277:13620-7.
    • (2002) J Biol Chem , vol.277 , pp. 13620-13627
    • Sakai, K.1    Lowman, H.B.2    Clemmons, D.R.3
  • 144
    • 0022494878 scopus 로고
    • Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats
    • Zapf J, Hauri C, Waldvogel M, Froesch ER. Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats. J Clin Invest. 1986;77:1768-75.
    • (1986) J Clin Invest , vol.77 , pp. 1768-1775
    • Zapf, J.1    Hauri, C.2    Waldvogel, M.3    Froesch, E.R.4
  • 145
    • 23244434632 scopus 로고    scopus 로고
    • Changes in insulin sensitivity induced by short-term growth hormone (GH) and insulin-like growth factor I (IGF-I) treatment in GH-deficient adults are not associated with changes in adiponectin levels
    • Schmid C, Bianda T, Zwimpfer C, Zapf J, Wiesli P. Changes in insulin sensitivity induced by short-term growth hormone (GH) and insulin-like growth factor I (IGF-I) treatment in GH-deficient adults are not associated with changes in adiponectin levels. Growth Horm IGF Res. 2005;15:300-3.
    • (2005) Growth Horm IGF Res , vol.15 , pp. 300-303
    • Schmid, C.1    Bianda, T.2    Zwimpfer, C.3    Zapf, J.4    Wiesli, P.5
  • 146
    • 0026740350 scopus 로고
    • Effects of insulin-like growth factor-I on glucose tolerance, insulin levels, and insulin secretion
    • Zenobi PD, Graf S, Ursprung H, Froesch ER. Effects of insulin-like growth factor-I on glucose tolerance, insulin levels, and insulin secretion. J Clin Invest. 1992;89:1908-13.
    • (1992) J Clin Invest , vol.89 , pp. 1908-1913
    • Zenobi, P.D.1    Graf, S.2    Ursprung, H.3    Froesch, E.R.4
  • 147
    • 0023276184 scopus 로고
    • Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults
    • Guler HP, Zapf J, Froesch ER. Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N Engl J Med. 1987;317:137-40.
    • (1987) N Engl J Med , vol.317 , pp. 137-140
    • Guler, H.P.1    Zapf, J.2    Froesch, E.R.3
  • 148
    • 0028300538 scopus 로고
    • Recombinant human insulin-like growth factor-I therapy improves glycemic control and insulin action in the type A syndrome of severe insulin resistance
    • Morrow LA, O'Brien MB, Moller DE, Flier JS, Moses AC. Recombinant human insulin-like growth factor-I therapy improves glycemic control and insulin action in the type A syndrome of severe insulin resistance. J Clin Endocrinol Metab. 1994;79:205-10.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 205-210
    • Morrow, L.A.1    O'Brien, M.B.2    Moller, D.E.3    Flier, J.S.4    Moses, A.C.5
  • 150
    • 4544238815 scopus 로고    scopus 로고
    • Dose-Dependent Effects of Recombinant Human Insulin-like Growth Factor (IGF)-I/IGF Binding Protein-3 Complex on Overnight Growth Hormone Secretion and Insulin Sensitivity in Type 1 Diabetes
    • Saukkonen T, Amin R, Williams RM, Fox C, Yuen KC, White MA, Umpleby AM, Acerini CL, Dunger DB. Dose-Dependent Effects of Recombinant Human Insulin-like Growth Factor (IGF)-I/IGF Binding Protein-3 Complex on Overnight Growth Hormone Secretion and Insulin Sensitivity in Type 1 Diabetes. Eur J Endocrinol. 2004;89:4634-41.
    • (2004) Eur J Endocrinol , vol.89 , pp. 4634-4641
    • Saukkonen, T.1    Amin, R.2    Williams, R.M.3    Fox, C.4    Yuen, K.C.5    White, M.A.6    Umpleby, A.M.7    Acerini, C.L.8    Dunger, D.B.9
  • 151
    • 0032417035 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor-I (rhIGF-I) therapy in adults with type 1 diabetes mellitus: effects on IGFs, IGF-binding proteins, glucose levels and insulin treatment
    • Carroll PV, Umpleby M, Alexander EL, Egel VA, Callison KV, Sönksen PH, Russell-Jones DL. Recombinant human insulin-like growth factor-I (rhIGF-I) therapy in adults with type 1 diabetes mellitus: effects on IGFs, IGF-binding proteins, glucose levels and insulin treatment. Clin Endocrinol (Oxf). 1998;49:739-46.
    • (1998) Clin Endocrinol (Oxf) , vol.49 , pp. 739-746
    • Carroll, P.V.1    Umpleby, M.2    Alexander, E.L.3    Egel, V.A.4    Callison, K.V.5    Sönksen, P.H.6    Russell-Jones, D.L.7
  • 152
    • 0028811130 scopus 로고
    • The effects of repeated daily recombinant human insulin-like growth factor I administration in adolescents with type 1 diabetes
    • Cheetham TD, Holly JM, Clayton K, Cwyfan-Hughes S, Dunger DB. The effects of repeated daily recombinant human insulin-like growth factor I administration in adolescents with type 1 diabetes. Diabet Med. 1995;12:885-92.
    • (1995) Diabet Med , vol.12 , pp. 885-892
    • Cheetham, T.D.1    Holly, J.M.2    Clayton, K.3    Cwyfan-Hughes, S.4    Dunger, D.B.5
  • 153
    • 0027074505 scopus 로고
    • Insulin-like growth factor-I improves glucose and lipid metabolism in type 2 diabetes mellitus
    • Zenobi PD, Jaeggi-Groisman SE, Riesen WF, Røder ME, Froesch ER. Insulin-like growth factor-I improves glucose and lipid metabolism in type 2 diabetes mellitus. J Clin Invest. 1992;90:2234-41.
    • (1992) J Clin Invest , vol.90 , pp. 2234-2241
    • Zenobi, P.D.1    Jaeggi-Groisman, S.E.2    Riesen, W.F.3    Røder, M.E.4    Froesch, E.R.5
  • 155
    • 0030032795 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes
    • Moses AC, Young SC, Morrow LA, O'Brien M, Clemmons DR. Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes. Diabetes. 1996;45:91-100.
    • (1996) Diabetes , vol.45 , pp. 91-100
    • Moses, A.C.1    Young, S.C.2    Morrow, L.A.3    O'Brien, M.4    Clemmons, D.R.5
  • 156
    • 0030453978 scopus 로고    scopus 로고
    • Increased expression of insulin/insulin-like growth factor-1 hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects
    • Federici M, Zucaro L, Porzio O, Massoud R, Borboni P, Lauro D, Sesti G. Increased expression of insulin/insulin-like growth factor-1 hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects. J Clin Invest. 1996;98:2887-93.
    • (1996) J Clin Invest , vol.98 , pp. 2887-2893
    • Federici, M.1    Zucaro, L.2    Porzio, O.3    Massoud, R.4    Borboni, P.5    Lauro, D.6    Sesti, G.7
  • 157
    • 0024552741 scopus 로고
    • Developmental expression of receptors for insulin, insulin-like growth factor I (IGF-I), and IGF-II in rat skeletal muscle
    • Alexandrides T, Moses AC, Smith RJ. Developmental expression of receptors for insulin, insulin-like growth factor I (IGF-I), and IGF-II in rat skeletal muscle. Endocrinology. 1989;124:1064-76.
    • (1989) Endocrinology , vol.124 , pp. 1064-1076
    • Alexandrides, T.1    Moses, A.C.2    Smith, R.J.3
  • 158
    • 0026452227 scopus 로고
    • Effect of increasing doses of recombinant human insulin-like growth factor-I on glucose, lipid, and leucine metabolism in man
    • Turkalj I, Keller U, Ninnis R, Vosmeer S, Stauffacher W. Effect of increasing doses of recombinant human insulin-like growth factor-I on glucose, lipid, and leucine metabolism in man. J Clin Endocrinol Metab. 1992;75:1186-91.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1186-1191
    • Turkalj, I.1    Keller, U.2    Ninnis, R.3    Vosmeer, S.4    Stauffacher, W.5
  • 159
    • 0031009731 scopus 로고    scopus 로고
    • Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors
    • Di Cola G, Cool MH, Accili D. Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors. J Clin Invest. 1997;99:2538-44.
    • (1997) J Clin Invest , vol.99 , pp. 2538-2544
    • Cola, G.1    Cool, M.H.2    Accili, D.3
  • 160
    • 84879117813 scopus 로고    scopus 로고
    • The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations
    • Berryman DE, Glad CAM, List EO, Johannsson G. The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations. Nat Rev Endocrinol. 2013;9:346-56.
    • (2013) Nat Rev Endocrinol , vol.9 , pp. 346-356
    • Berryman, D.E.1    Glad, C.A.M.2    List, E.O.3    Johannsson, G.4
  • 163
    • 33646810078 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor-I treatment inhibits gluconeogenesis in a transgenic mouse model of type 2 diabetes mellitus
    • Pennisi P, Gavrilova O, Setser-Portas J, Jou W, Santopietro S, Clemmons D, Yakar S, LeRoith D. Recombinant human insulin-like growth factor-I treatment inhibits gluconeogenesis in a transgenic mouse model of type 2 diabetes mellitus. Endocrinology. 2006;147:2619-30.
    • (2006) Endocrinology , vol.147 , pp. 2619-2630
    • Pennisi, P.1    Gavrilova, O.2    Setser-Portas, J.3    Jou, W.4    Santopietro, S.5    Clemmons, D.6    Yakar, S.7    LeRoith, D.8
  • 165
    • 33845541643 scopus 로고    scopus 로고
    • Therapeutic aspects of growth hormone and insulin-like growth factor-I treatment on visceral fat and insulin sensitivity in adults
    • Yuen KCJ, Dunger DB. Therapeutic aspects of growth hormone and insulin-like growth factor-I treatment on visceral fat and insulin sensitivity in adults. Diabetes Obes Metab. 2007;9:11-22.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 11-22
    • Yuen, K.C.J.1    Dunger, D.B.2
  • 166
  • 168
    • 4444284454 scopus 로고    scopus 로고
    • Free insulin-like growth factors-measurements and relationships to growth hormone secretion and glucose homeostasis
    • Frystyk J. Free insulin-like growth factors-measurements and relationships to growth hormone secretion and glucose homeostasis. Growth Hormone IGF Res. 2004;14:337-75.
    • (2004) Growth Hormone IGF Res , vol.14 , pp. 337-375
    • Frystyk, J.1
  • 169
    • 0026694055 scopus 로고
    • Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans
    • Conover CA, Lee PD, Kanaley JA, Clarkson JT, Jensen MD. Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans. J Clin Endocrinol Metab. 1992;74:1355-60.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1355-1360
    • Conover, C.A.1    Lee, P.D.2    Kanaley, J.A.3    Clarkson, J.T.4    Jensen, M.D.5
  • 170
    • 0030993358 scopus 로고    scopus 로고
    • Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone
    • Nam SY, Lee EJ, Kim KR, Cha BS, Song YD, Lim SK, Lee HC, Huh KB. Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone. Int J Obes Relat Metab Disord. 1997;21:355-9.
    • (1997) Int J Obes Relat Metab Disord , vol.21 , pp. 355-359
    • Nam, S.Y.1    Lee, E.J.2    Kim, K.R.3    Cha, B.S.4    Song, Y.D.5    Lim, S.K.6    Lee, H.C.7    Huh, K.B.8
  • 171
    • 0029134591 scopus 로고
    • Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures
    • Henry RR, Abrams L, Nikoulina S, Ciaraldi TP. Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures. Diabetes. 1995;44:936-46.
    • (1995) Diabetes , vol.44 , pp. 936-946
    • Henry, R.R.1    Abrams, L.2    Nikoulina, S.3    Ciaraldi, T.P.4
  • 172
    • 0033305021 scopus 로고    scopus 로고
    • Insulin-like growth factor I circumvents defective insulin action in human myotonic dystrophy skeletal muscle cells
    • Furling D, Marette A, Puymirat J. Insulin-like growth factor I circumvents defective insulin action in human myotonic dystrophy skeletal muscle cells. Endocrinology. 1999;140:4244-50.
    • (1999) Endocrinology , vol.140 , pp. 4244-4250
    • Furling, D.1    Marette, A.2    Puymirat, J.3
  • 173
    • 0025993834 scopus 로고
    • Variables controlling the secretion of insulin-like growth factor binding protein-2 in normal human subjects
    • Clemmons DR, Snyder DK, Busby WH. Variables controlling the secretion of insulin-like growth factor binding protein-2 in normal human subjects. J Clin Endocrinol Metab. 1991;73:727-33.
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 727-733
    • Clemmons, D.R.1    Snyder, D.K.2    Busby, W.H.3
  • 175
    • 0034604529 scopus 로고    scopus 로고
    • Nuclear import of Insulin-like Growth Factor-binding Protein-3 and -5 is mediated by the importin ? Subunit
    • Schedlich LJ, Le Page SL, Firth SM, Briggs LJ, Jans DA, Baxter RC. Nuclear import of Insulin-like Growth Factor-binding Protein-3 and -5 is mediated by the importin ? Subunit. J Biol Chem. 2000;275:23462-70.
    • (2000) J Biol Chem , vol.275 , pp. 23462-23470
    • Schedlich, L.J.1    Page, S.L.2    Firth, S.M.3    Briggs, L.J.4    Jans, D.A.5    Baxter, R.C.6
  • 177
    • 0036838455 scopus 로고    scopus 로고
    • Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice
    • Silha JV, Gui Y, Murphy LJ. Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice. Am J Physiol Endocrinol Metab. 2002;283:E937-45.
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , pp. E937-E945
    • Silha, J.V.1    Gui, Y.2    Murphy, L.J.3
  • 180
    • 1842472264 scopus 로고    scopus 로고
    • Detection of the differentially expressed gene IGF-binding protein-related protein-1 and analysis of its relationship to fasting glucose in Chinese colorectal cancer patients
    • Shao L, Huang Q, Luo M, Lai M. Detection of the differentially expressed gene IGF-binding protein-related protein-1 and analysis of its relationship to fasting glucose in Chinese colorectal cancer patients. Endocr Relat Cancer. 2004;11:141-8.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 141-148
    • Shao, L.1    Huang, Q.2    Luo, M.3    Lai, M.4
  • 181
    • 3242686718 scopus 로고    scopus 로고
    • Insulin-like growth factor-I stimulates both cell growth and lipogenesis during differentiation of human mesenchymal stem cells into adipocytes
    • Scavo LM, Karas M, Murray M, Leroith D. Insulin-like growth factor-I stimulates both cell growth and lipogenesis during differentiation of human mesenchymal stem cells into adipocytes. J Clin Endocrinol Metab. 2004;89:3543-53.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3543-3553
    • Scavo, L.M.1    Karas, M.2    Murray, M.3    Leroith, D.4
  • 182
    • 0022476694 scopus 로고
    • Specific binding of human growth hormone but not insulin-like growth factors by human adipocytes
    • DiGirolamo M, Edén S, Enberg G, Isaksson O, Lönnroth P, Hall K, Smith U. Specific binding of human growth hormone but not insulin-like growth factors by human adipocytes. FEBS Lett. 1986;205:15-9.
    • (1986) FEBS Lett , vol.205 , pp. 15-19
    • DiGirolamo, M.1    Edén, S.2    Enberg, G.3    Isaksson, O.4    Lönnroth, P.5    Hall, K.6    Smith, U.7
  • 183
    • 0034458011 scopus 로고    scopus 로고
    • Insulin-like growth factor I and growth hormone (GH) treatment in GH-deficient humans: differential effects on protein, glucose, lipid, and calcium metabolism
    • Mauras N, O'Brien KO, Welch S, Rini A, Helgeson K, Vieira NE, Yergey AL. Insulin-like growth factor I and growth hormone (GH) treatment in GH-deficient humans: differential effects on protein, glucose, lipid, and calcium metabolism. J Clin Endocrinol Metab. 2000;85:1689-94.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1689-1694
    • Mauras, N.1    O'Brien, K.O.2    Welch, S.3    Rini, A.4    Helgeson, K.5    Vieira, N.E.6    Yergey, A.L.7
  • 184
    • 85047690242 scopus 로고    scopus 로고
    • The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity
    • Clemmons DR. The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity. J Clin Invest. 2004;113:25-27.
    • (2004) J Clin Invest , vol.113 , pp. 25-27
    • Clemmons, D.R.1
  • 185
    • 33847221165 scopus 로고    scopus 로고
    • Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1
    • LeRoith D, Yakar S. Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1. Nat Clin Pract Endocrinol Metab. 2007;3:302-10.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , pp. 302-310
    • LeRoith, D.1    Yakar, S.2
  • 186
    • 0035210333 scopus 로고    scopus 로고
    • The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice
    • Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 2001;142:5182-9.
    • (2001) Endocrinology , vol.142 , pp. 5182-5189
    • Heffernan, M.1    Summers, R.J.2    Thorburn, A.3    Ogru, E.4    Gianello, R.5    Jiang, W.J.6    Ng, F.M.7
  • 187
    • 0027287413 scopus 로고
    • Fat cell adrenergic receptors and the control of white and brown fat cell function
    • Lafontan M, Berlan M. Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res. 1993;34:1057-91.
    • (1993) J Lipid Res , vol.34 , pp. 1057-1091
    • Lafontan, M.1    Berlan, M.2
  • 188
    • 0026031870 scopus 로고
    • Relationship between lipolysis and cyclic AMP generation mediated by atypical beta-adrenoceptors in rat adipocytes
    • Hollenga C, Brouwer F, Zaagsma J. Relationship between lipolysis and cyclic AMP generation mediated by atypical beta-adrenoceptors in rat adipocytes. Br J Pharmacol. 1991;102:577-80.
    • (1991) Br J Pharmacol , vol.102 , pp. 577-580
    • Hollenga, C.1    Brouwer, F.2    Zaagsma, J.3
  • 190
    • 0035218344 scopus 로고    scopus 로고
    • Inhibition of the rise in FFA by Acipimox partially prevents GH-induced insulin resistance in GH-deficient adults
    • Segerlantz M, Bramnert M, Manhem P, Laurila E, Groop LC. Inhibition of the rise in FFA by Acipimox partially prevents GH-induced insulin resistance in GH-deficient adults. J Clin Endocrinol Metab. 2001;86:5813-8.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5813-5818
    • Segerlantz, M.1    Bramnert, M.2    Manhem, P.3    Laurila, E.4    Groop, L.C.5
  • 192
    • 8744259926 scopus 로고    scopus 로고
    • Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance
    • Zick Y. Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance. Biochem Soc Trans. 2004;32:812-6.
    • (2004) Biochem Soc Trans , vol.32 , pp. 812-816
    • Zick, Y.1
  • 197
    • 0033709675 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor I has significant anabolic effects in adults with growth hormone receptor deficiency: studies on protein, glucose, and lipid metabolism
    • Mauras N, Martinez V, Rini A, Guevara-Aguirre J. Recombinant human insulin-like growth factor I has significant anabolic effects in adults with growth hormone receptor deficiency: studies on protein, glucose, and lipid metabolism. 2000;85:3036-42.
    • (2000) , vol.85 , pp. 3036-3042
    • Mauras, N.1    Martinez, V.2    Rini, A.3    Guevara-Aguirre, J.4
  • 198
    • 84861982113 scopus 로고    scopus 로고
    • Metabolic actions of insulin-like growth factor-I in normal physiology and diabetes
    • Clemmons DR. Metabolic actions of insulin-like growth factor-I in normal physiology and diabetes. Endocrinol Metab Clin North Am. 2012;41:425-43.
    • (2012) Endocrinol Metab Clin North Am , vol.41 , pp. 425-443
    • Clemmons, D.R.1
  • 199
    • 42449105754 scopus 로고    scopus 로고
    • Low doses of insulin-like growth factor I improve insulin resistance, lipid metabolism, and oxidative damage in aging rats
    • García-Fernández M, Delgado G, Puche JE, González-Barón S, Cortázar IC. Low doses of insulin-like growth factor I improve insulin resistance, lipid metabolism, and oxidative damage in aging rats. Endocrinology. 2008;149:2433-42.
    • (2008) Endocrinology , vol.149 , pp. 2433-2442
    • García-Fernández, M.1    Delgado, G.2    Puche, J.E.3    González-Barón, S.4    Cortázar, I.C.5
  • 200
    • 84863115697 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function
    • Zhang Y, Yuan M, Bradley KM, Dong F, Anversa P, Ren J. Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function. Hypertension. 2012;59:680-93.
    • (2012) Hypertension , vol.59 , pp. 680-693
    • Zhang, Y.1    Yuan, M.2    Bradley, K.M.3    Dong, F.4    Anversa, P.5    Ren, J.6
  • 202
    • 0036636255 scopus 로고    scopus 로고
    • Inactivation of muscle insulin and IGF-I receptors and insulin responsiveness
    • Le Roith D, Kim H, Fernandez AM, Accili D. Inactivation of muscle insulin and IGF-I receptors and insulin responsiveness. Curr Opin Clin Nutr Metab Care. 2002;5:371-5.
    • (2002) Curr Opin Clin Nutr Metab Care , vol.5 , pp. 371-375
    • Roith, D.1    Kim, H.2    Fernandez, A.M.3    Accili, D.4
  • 204
    • 0024522272 scopus 로고
    • Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat
    • Jacob R, Barrett E, Plewe G, Fagin KD, Sherwin RS. Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. Comp Insulin J Clin Invest. 1989;83:1717-23.
    • (1989) Comp Insulin J Clin Invest , vol.83 , pp. 1717-1723
    • Jacob, R.1    Barrett, E.2    Plewe, G.3    Fagin, K.D.4    Sherwin, R.S.5
  • 207
    • 70350594050 scopus 로고    scopus 로고
    • Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects
    • Succurro E, Andreozzi F, Marini MA, Lauro R, Hribal ML, Perticone F, Sesti G. Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects. Nutr Metab Cardiovasc Dis. 2009;19:713-9.
    • (2009) Nutr Metab Cardiovasc Dis , vol.19 , pp. 713-719
    • Succurro, E.1    Andreozzi, F.2    Marini, M.A.3    Lauro, R.4    Hribal, M.L.5    Perticone, F.6    Sesti, G.7
  • 208
    • 0037129721 scopus 로고    scopus 로고
    • Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study
    • Sandhu MS, Heald AH, Gibson JM, Cruickshank JK, Dunger DB, Wareham NJ. Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study. Lancet. 2002;359:1740-5.
    • (2002) Lancet , vol.359 , pp. 1740-1745
    • Sandhu, M.S.1    Heald, A.H.2    Gibson, J.M.3    Cruickshank, J.K.4    Dunger, D.B.5    Wareham, N.J.6
  • 209
    • 0036738463 scopus 로고    scopus 로고
    • IGF-I/IGF-binding protein-3 combination improves insulin resistance by GH-dependent and independent mechanisms
    • O'Connell T, Clemmons DR. IGF-I/IGF-binding protein-3 combination improves insulin resistance by GH-dependent and independent mechanisms. J Clin Endocrinol Metab. 2002;87:4356-60.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4356-4360
    • O'Connell, T.1    Clemmons, D.R.2
  • 211
    • 0028941256 scopus 로고
    • Effect of insulin on the insulin-like growth factor system in children with new-onset insulin-dependent diabetes mellitus
    • Bereket A, Lang CH, Blethen SL, Gelato MC, Fan J, Frost RA, Wilson TA. Effect of insulin on the insulin-like growth factor system in children with new-onset insulin-dependent diabetes mellitus. 1995;80:1312-7.
    • (1995) , vol.80 , pp. 1312-1317
    • Bereket, A.1    Lang, C.H.2    Blethen, S.L.3    Gelato, M.C.4    Fan, J.5    Frost, R.A.6    Wilson, T.A.7
  • 212
    • 84855272505 scopus 로고    scopus 로고
    • Pathophysiology of the metabolic syndrome: implications for the cardiometabolic risks associated with type 2 diabetes
    • Leroith D. Pathophysiology of the metabolic syndrome: implications for the cardiometabolic risks associated with type 2 diabetes. Am J Med Sci. 2012;343:13-6.
    • (2012) Am J Med Sci , vol.343 , pp. 13-16
    • Leroith, D.1
  • 213
    • 77953644471 scopus 로고    scopus 로고
    • Association of metabolic syndrome with insulin-like growth factors among adults in the US
    • Saydah S, Ballard-Barbash R, Potischman N. Association of metabolic syndrome with insulin-like growth factors among adults in the US. Cancer Causes Control. 2009;20:1309-16.
    • (2009) Cancer Causes Control , vol.20 , pp. 1309-1316
    • Saydah, S.1    Ballard-Barbash, R.2    Potischman, N.3
  • 214
    • 84893654266 scopus 로고    scopus 로고
    • A fasting insulin-raising allele at IGF1 locus is associated with circulating levels of IGF-1 and insulin sensitivity
    • Mannino GC, Greco A, De Lorenzo C, Andreozzi F, Marini MA, Perticone F, Sesti G. A fasting insulin-raising allele at IGF1 locus is associated with circulating levels of IGF-1 and insulin sensitivity. PLoS One. 2013;8.
    • (2013) PLoS One , pp. 8
    • Mannino, G.C.1    Greco, A.2    De Lorenzo, C.3    Andreozzi, F.4    Marini, M.A.5    Perticone, F.6    Sesti, G.7
  • 216
    • 84919483077 scopus 로고    scopus 로고
    • The complex relationship between obesity and the somatropic axis : the long and winding road
    • Savastano S, Di C, Barrea L, Colao A. The complex relationship between obesity and the somatropic axis : the long and winding road. YGHIR. 2014;24:221-6.
    • (2014) YGHIR , vol.24 , pp. 221-226
    • Savastano, S.1    Di, C.2    Barrea, L.3    Colao, A.4
  • 222
    • 49649106996 scopus 로고    scopus 로고
    • The GH-IGF-I axis and the cardiovascular system: Clinical implications
    • Colao A. The GH-IGF-I axis and the cardiovascular system: Clinical implications. Clin. Endocr. 2008;69:347-58.
    • (2008) Clin. Endocr , vol.69 , pp. 347-358
    • Colao, A.1
  • 223
    • 84862909334 scopus 로고    scopus 로고
    • The Insulin-Like growth factor system, metabolic syndrome, and cardiovascular disease risk
    • Akanji AO, Smith RJ. The Insulin-Like growth factor system, metabolic syndrome, and cardiovascular disease risk. Metab Syndr Relat Disor. 2012;10:3-13.
    • (2012) Metab Syndr Relat Disor , vol.10 , pp. 3-13
    • Akanji, A.O.1    Smith, R.J.2
  • 224
    • 17244372789 scopus 로고    scopus 로고
    • Insulin-like growth factor I and impaired glucose tolerance
    • Dunger D, Yuen K, Ong K. Insulin-like growth factor I and impaired glucose tolerance. Horm Res. 2004;62:101-7.
    • (2004) Horm Res , vol.62 , pp. 101-107
    • Dunger, D.1    Yuen, K.2    Ong, K.3
  • 225
    • 53849092099 scopus 로고    scopus 로고
    • Study of insulin resistance in relation to serum IGF-I levels in subjects with different degrees of glucose tolerance
    • Martha S, Pantam N, Thungathurthi S, Rao VLN, Devarakonda K. Study of insulin resistance in relation to serum IGF-I levels in subjects with different degrees of glucose tolerance. Int J Diabetes Dev Ctries. 2008;28:54-9.
    • (2008) Int J Diabetes Dev Ctries , vol.28 , pp. 54-59
    • Martha, S.1    Pantam, N.2    Thungathurthi, S.3    Rao, V.L.N.4    Devarakonda, K.5
  • 228
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker J, Liu JP, Robertson EJ, Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell. 1993;75:73-82.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 231
    • 79951708410 scopus 로고    scopus 로고
    • Association between serum IGF-1 and diabetes among US adults
    • Teppala S, Shankar A. Association between serum IGF-1 and diabetes among US adults. Diabetes Care. 2010;33:2257-9.
    • (2010) Diabetes Care , vol.33 , pp. 2257-2259
    • Teppala, S.1    Shankar, A.2
  • 235
    • 21244481313 scopus 로고    scopus 로고
    • Insulin-like growth factor-I and risk of type 2 diabetes and coronary heart disease: molecular epidemiology
    • Sandhu MS. Insulin-like growth factor-I and risk of type 2 diabetes and coronary heart disease: molecular epidemiology. Endocr Dev. 2005;9:44-54.
    • (2005) Endocr Dev , vol.9 , pp. 44-54
    • Sandhu, M.S.1
  • 236
    • 33644848669 scopus 로고    scopus 로고
    • Mouse models created to study the pathophysiology of Type 2 diabetes
    • LeRoith D, Gavrilova O. Mouse models created to study the pathophysiology of Type 2 diabetes. Int J Biochem Cell Biol. 2006;38:904-12.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 904-912
    • LeRoith, D.1    Gavrilova, O.2
  • 238
    • 0346724282 scopus 로고    scopus 로고
    • Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: Does insulin-like growth factor-I play a role?
    • Jensen RBB, Chellakooty M, Vielwerth S, Vaag A, Larsen T, Greisen G, Skakkebæk NE, Scheike T, Juul A. Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: Does insulin-like growth factor-I play a role? Horm Res. 2003;60(suppl 3):136-48.
    • (2003) Horm Res. , vol.60 , pp. 136-148
    • Jensen, R.B.B.1    Chellakooty, M.2    Vielwerth, S.3    Vaag, A.4    Larsen, T.5    Greisen, G.6    Skakkebæk, N.E.7    Scheike, T.8    Juul, A.9
  • 242
    • 0028348734 scopus 로고
    • The impact of obesity, fat distribution, and energy restriction on insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, insulin, and growth hormone
    • Rasmussen MH, Frystyk J, Andersen T, Breum L, Christiansen JS, Hilsted J. The impact of obesity, fat distribution, and energy restriction on insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, insulin, and growth hormone. Metabolism. 1994;43:315-9.
    • (1994) Metabolism , vol.43 , pp. 315-319
    • Rasmussen, M.H.1    Frystyk, J.2    Andersen, T.3    Breum, L.4    Christiansen, J.S.5    Hilsted, J.6
  • 243
    • 0032198734 scopus 로고    scopus 로고
    • Divergent effects of short-term, very-low-calorie diet on insulin-like growth factor-I and insulin-like growth factor binding protein-3 serum concentrations in premenopausal women with obesity
    • De Pergola G, Zamboni M, Pannacciulli N, Turcato E, Giorgino F, Armellini F, Logoluso F, Sciaraffia M, Bosello O, Giorgino R. Divergent effects of short-term, very-low-calorie diet on insulin-like growth factor-I and insulin-like growth factor binding protein-3 serum concentrations in premenopausal women with obesity. Obes Res. 1998;6:408-15.
    • (1998) Obes Res , vol.6 , pp. 408-415
    • Pergola, G.1    Zamboni, M.2    Pannacciulli, N.3    Turcato, E.4    Giorgino, F.5    Armellini, F.6    Logoluso, F.7    Sciaraffia, M.8    Bosello, O.9    Giorgino, R.10
  • 246
    • 0028953083 scopus 로고
    • Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects
    • Rasmussen MH, Hvidberg A, Juul A, Main KM, Gotfredsen A, Skakkebae NE, Hilsted J. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects. J Clin Endocrinol Metab. 1995;80:1407-15.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1407-1415
    • Rasmussen, M.H.1    Hvidberg, A.2    Juul, A.3    Main, K.M.4    Gotfredsen, A.5    Skakkebae, N.E.6    Hilsted, J.7
  • 247
    • 0032955687 scopus 로고    scopus 로고
    • Regulation of IGF binding protein-1 in hep G2 cells by cytokines and reactive oxygen species
    • Lang CH, Nystrom GJ, Frost RA. Regulation of IGF binding protein-1 in hep G2 cells by cytokines and reactive oxygen species. Am J Physiol. 1999;276(3 Pt 1):G719-27.
    • (1999) Am J Physiol , vol.276 , Issue.3 , pp. G719-G727
    • Lang, C.H.1    Nystrom, G.J.2    Frost, R.A.3
  • 248
    • 0028789723 scopus 로고
    • Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by tumor necrosis factor
    • Fan J, Char D, Bagby GJ, Gelato MC, Lang CH. Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by tumor necrosis factor. Am J Physiol. 1995;269(5 Pt 2):R1204-12.
    • (1995) Am J Physiol , vol.269 , Issue.5 , pp. R1204-R1212
    • Fan, J.1    Char, D.2    Bagby, G.J.3    Gelato, M.C.4    Lang, C.H.5
  • 251
    • 4344622579 scopus 로고    scopus 로고
    • Diabetic retinopathy in two patients with congenital IGF-I deficiency (Laron syndrome)
    • Laron Z, Weinberger D. Diabetic retinopathy in two patients with congenital IGF-I deficiency (Laron syndrome). Eur J Endocrinol. 2004;151:103-6.
    • (2004) Eur J Endocrinol , vol.151 , pp. 103-106
    • Laron, Z.1    Weinberger, D.2
  • 252
    • 0043264091 scopus 로고    scopus 로고
    • C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups
    • Heald AH, Anderson SG, Ivison F, Laing I, Gibson JM, Cruickshank K. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis. 2003;170:79-86.
    • (2003) Atherosclerosis , vol.170 , pp. 79-86
    • Heald, A.H.1    Anderson, S.G.2    Ivison, F.3    Laing, I.4    Gibson, J.M.5    Cruickshank, K.6
  • 253
    • 67349108377 scopus 로고    scopus 로고
    • Low levels of insulin-like growth-factor-binding protein-1 (IGFBP-1) are prospectively associated with the incidence of type 2 diabetes and impaired glucose tolerance (IGT): the Söderåkra Cardiovascular Risk Factor Study
    • Petersson U, Östgren CJ, Brudin L, Brismar K, Nilsson PM. Low levels of insulin-like growth-factor-binding protein-1 (IGFBP-1) are prospectively associated with the incidence of type 2 diabetes and impaired glucose tolerance (IGT): the Söderåkra Cardiovascular Risk Factor Study. Diabetes Metab. 2009;35:198-205.
    • (2009) Diabetes Metab , vol.35 , pp. 198-205
    • Petersson, U.1    Östgren, C.J.2    Brudin, L.3    Brismar, K.4    Nilsson, P.M.5
  • 254
    • 0026005865 scopus 로고
    • Insulin-like growth factor-binding protein-1 modulates blood glucose levels
    • Lewitt MS, Denyer GS, Cooney GJ, Baxter RC. Insulin-like growth factor-binding protein-1 modulates blood glucose levels. Endocrinology. 1991;129:2254-6.
    • (1991) Endocrinology , vol.129 , pp. 2254-2256
    • Lewitt, M.S.1    Denyer, G.S.2    Cooney, G.J.3    Baxter, R.C.4
  • 255
    • 0032721646 scopus 로고    scopus 로고
    • Circulating levels of free insulin-like growth factors in obese subjects: the impact of type 2 diabetes
    • Frystyk J, Skjaerbaek C, Vestbo E, Fisker S, Orskov H. Circulating levels of free insulin-like growth factors in obese subjects: the impact of type 2 diabetes. Diabetes Metab Res Rev. 1999;15:314-22.
    • (1999) Diabetes Metab Res Rev , vol.15 , pp. 314-322
    • Frystyk, J.1    Skjaerbaek, C.2    Vestbo, E.3    Fisker, S.4    Orskov, H.5
  • 256
  • 257
    • 0031967735 scopus 로고    scopus 로고
    • The effects of recombinant human IGF-I administration on concentrations of acid labile subunit, IGF binding protein-3, IGF-I, IGF-ii and proteolysis of IGF binding protein-3 in adolescents with insulin-dependent diabetes mellitus
    • Cheetham TD, Holly JMP, Baxter RC, Meadows K, Jones J, Taylor AM, Dunger DB. The effects of recombinant human IGF-I administration on concentrations of acid labile subunit, IGF binding protein-3, IGF-I, IGF-ii and proteolysis of IGF binding protein-3 in adolescents with insulin-dependent diabetes mellitus. J Endocrinol. 1998;157:81-7.
    • (1998) J Endocrinol , vol.157 , pp. 81-87
    • Cheetham, T.D.1    Holly, J.M.P.2    Baxter, R.C.3    Meadows, K.4    Jones, J.5    Taylor, A.M.6    Dunger, D.B.7
  • 258
    • 0028211161 scopus 로고
    • Increased proteolysis of insulin-like growth factor-binding protein-3 (IGFBP-3) in Noninsulin-dependent diabetes mellitus serum, with elevation of a 29-kilodalton (kDa) glycosylated IGFBP-3 fragment contained in the approximately 130- To 150-kDa Ternary C
    • Bang P, Brismar K, Rosenfeld RG. Increased proteolysis of insulin-like growth factor-binding protein-3 (IGFBP-3) in Noninsulin-dependent diabetes mellitus serum, with elevation of a 29-kilodalton (kDa) glycosylated IGFBP-3 fragment contained in the approximately 130- To 150-kDa Ternary C. J Clin Endocrinol Metab. 1994;78:1119-27.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1119-1127
    • Bang, P.1    Brismar, K.2    Rosenfeld, R.G.3
  • 259
    • 0035157508 scopus 로고    scopus 로고
    • Physiological differences in insulin-like growth factor binding protein-1 (IGFBP-1) phosphorylation in IGFBP-1 transgenic mice
    • Sakai K, D'Ercole AJ, Murphy LJ, Clemmons DR. Physiological differences in insulin-like growth factor binding protein-1 (IGFBP-1) phosphorylation in IGFBP-1 transgenic mice. Diabetes. 2001;50:32-8.
    • (2001) Diabetes , vol.50 , pp. 32-38
    • Sakai, K.1    D'Ercole, A.J.2    Murphy, L.J.3    Clemmons, D.R.4
  • 260
    • 79960364308 scopus 로고    scopus 로고
    • Longitudinal association between IGFBP-1 levels and parameters of the metabolic syndrome in obese children before and after weight loss
    • Reinehr T, Kleber M, Toschke AM, Woelfle J, Roth CL. Longitudinal association between IGFBP-1 levels and parameters of the metabolic syndrome in obese children before and after weight loss. Int J Pediatr Obes. 2011;6:236-43.
    • (2011) Int J Pediatr Obes , vol.6 , pp. 236-243
    • Reinehr, T.1    Kleber, M.2    Toschke, A.M.3    Woelfle, J.4    Roth, C.L.5
  • 261
    • 0029850504 scopus 로고    scopus 로고
    • Insulin-like growth factors and their binding proteins before and after weight loss and their associations with hormonal and metabolic parameters in obese adolescent girls
    • Wabitsch M, Blum WF, Muche R, Heinze E, Haug C, Mayer H, Teller W. Insulin-like growth factors and their binding proteins before and after weight loss and their associations with hormonal and metabolic parameters in obese adolescent girls. Int J Obes Relat Metab Disord. 1996;20:1073-80.
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 1073-1080
    • Wabitsch, M.1    Blum, W.F.2    Muche, R.3    Heinze, E.4    Haug, C.5    Mayer, H.6    Teller, W.7
  • 263
    • 84859158181 scopus 로고    scopus 로고
    • Therapeutic potential of PEGylated insulin-like growth factor I for skeletal muscle disease evaluated in two murine models of muscular dystrophy
    • Gehrig SM, van der Poel C, Hoeflich A, Naim T, Lynch GS, Metzger F. Therapeutic potential of PEGylated insulin-like growth factor I for skeletal muscle disease evaluated in two murine models of muscular dystrophy. Growth Horm IGF Res. 2012;22:69-75.
    • (2012) Growth Horm IGF Res , vol.22 , pp. 69-75
    • Gehrig, S.M.1    Poel, C.2    Hoeflich, A.3    Naim, T.4    Lynch, G.S.5    Metzger, F.6
  • 264
    • 17744390350 scopus 로고    scopus 로고
    • GHIS Collaborative Group. Growth hormone insensitivity syndrome: therapy for 6.5-7.5 years with recombinant insulin-like growth factor I in children with growth hormone insensitivity syndrome: a clinical research center study
    • Backeljauw PF, Underwood LE. GHIS Collaborative Group. Growth hormone insensitivity syndrome: therapy for 6.5-7.5 years with recombinant insulin-like growth factor I in children with growth hormone insensitivity syndrome: a clinical research center study. J Clin Endocrinol Metab. 2001;86:1504-10.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1504-1510
    • Backeljauw, P.F.1    Underwood, L.E.2
  • 267
    • 0033393584 scopus 로고    scopus 로고
    • Growth response to rhIGF-I 80 microg/kg twice daily in children with growth hormone insensitivity syndrome: relationship to severity of clinical phenotype
    • Azcona C, Preece MA, Rose SJ, Fraser N, Rappaport R, Ranke MB, Savage MO. Growth response to rhIGF-I 80 microg/kg twice daily in children with growth hormone insensitivity syndrome: relationship to severity of clinical phenotype. Clin Endocrinol (Oxf). 1999;51:787-92.
    • (1999) Clin Endocrinol (Oxf) , vol.51 , pp. 787-792
    • Azcona, C.1    Preece, M.A.2    Rose, S.J.3    Fraser, N.4    Rappaport, R.5    Ranke, M.B.6    Savage, M.O.7
  • 268
    • 0032771876 scopus 로고    scopus 로고
    • Long-term treatment of growth hormone insensitivity syndrome with IGF-I. Results of the European Multicentre Study. The Working Group on Growth Hormone Insensitivity Syndromes
    • Ranke MB, Savage MO, Chatelain PG, Preece MA, Rosenfeld RG, Wilton P. Long-term treatment of growth hormone insensitivity syndrome with IGF-I. Results of the European Multicentre Study. The Working Group on Growth Hormone Insensitivity Syndromes. Horm Res. 1999;51:128-34.
    • (1999) Horm Res , vol.51 , pp. 128-134
    • Ranke, M.B.1    Savage, M.O.2    Chatelain, P.G.3    Preece, M.A.4    Rosenfeld, R.G.5    Wilton, P.6
  • 270
    • 0033976363 scopus 로고    scopus 로고
    • Insulinlike growth factor I plus insulinlike growth factor binding protein 3 attenuates the proinflammatory acute phase response in severely burned children
    • Jeschke MG, Barrow RE, Herndon DN. Insulinlike growth factor I plus insulinlike growth factor binding protein 3 attenuates the proinflammatory acute phase response in severely burned children. Ann Surg. 2000;231:246-52.
    • (2000) Ann Surg , vol.231 , pp. 246-252
    • Jeschke, M.G.1    Barrow, R.E.2    Herndon, D.N.3
  • 271
    • 0035512592 scopus 로고    scopus 로고
    • IGF-I/BP-3 administration preserves hepatic homeostasis after thermal injury which is associated with increases in no and hepatic NF-kappa B
    • Jeschke MG, Herndon DN, Vita R, Traber DL, Jauch KW, Barrow RE. IGF-I/BP-3 administration preserves hepatic homeostasis after thermal injury which is associated with increases in no and hepatic NF-kappa B. Shock. 2001;16:373-9.
    • (2001) Shock , vol.16 , pp. 373-379
    • Jeschke, M.G.1    Herndon, D.N.2    Vita, R.3    Traber, D.L.4    Jauch, K.W.5    Barrow, R.E.6
  • 272
    • 0036157108 scopus 로고    scopus 로고
    • Modulation of types I and II acute phase reactants with insulin-like growth factor-1/binding protein-3 complex in severely burned children
    • Spies M, Wolf SE, Barrow RE, Jeschke MG, Herndon DN. Modulation of types I and II acute phase reactants with insulin-like growth factor-1/binding protein-3 complex in severely burned children. Crit Care Med. 2002;30:83-8.
    • (2002) Crit Care Med , vol.30 , pp. 83-88
    • Spies, M.1    Wolf, S.E.2    Barrow, R.E.3    Jeschke, M.G.4    Herndon, D.N.5
  • 273
    • 0032707297 scopus 로고    scopus 로고
    • Anabolic effects of insulin-like growth factor in combination with insulin-like growth factor binding protein-3 in severely burned adults
    • (discussion 910-1)
    • Debroy MA, Wolf SE, Zhang XJ, Chinkes DL, Ferrando AA, Wolfe RR, Herndon DN. Anabolic effects of insulin-like growth factor in combination with insulin-like growth factor binding protein-3 in severely burned adults. J Trauma. 1999;47:904-10 (discussion 910-1).
    • (1999) J Trauma , vol.47 , pp. 904-910
    • Debroy, M.A.1    Wolf, S.E.2    Zhang, X.J.3    Chinkes, D.L.4    Ferrando, A.A.5    Wolfe, R.R.6    Herndon, D.N.7
  • 274
    • 0036078286 scopus 로고    scopus 로고
    • Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa
    • Grinspoon S, Thomas L, Miller K, Herzog D, Klibanski A. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J Clin Endocrinol Metab. 2002;87:2883-91.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2883-2891
    • Grinspoon, S.1    Thomas, L.2    Miller, K.3    Herzog, D.4    Klibanski, A.5
  • 275
  • 276
    • 23244460727 scopus 로고    scopus 로고
    • Rh/IGF-I/rhIGFBP-3 administration to patients with type 2 diabetes mellitus reduces insulin requirements while also lowering fasting glucose
    • Clemmons DR, Moses AC, Sommer A, Jacobson W, Rogol AD, Sleevi MR, Allan G. Rh/IGF-I/rhIGFBP-3 administration to patients with type 2 diabetes mellitus reduces insulin requirements while also lowering fasting glucose. Growth Horm IGF Res. 2005;15:265-74.
    • (2005) Growth Horm IGF Res , vol.15 , pp. 265-274
    • Clemmons, D.R.1    Moses, A.C.2    Sommer, A.3    Jacobson, W.4    Rogol, A.D.5    Sleevi, M.R.6    Allan, G.7
  • 277
    • 0034456332 scopus 로고    scopus 로고
    • The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evidence for in vivo biological activity
    • Clemmons DR, Moses AC, McKay MJ, Sommer A, Rosen DM, Ruckle J. The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evidence for in vivo biological activity. J Clin Endocrinol Metab. 2000;85:1518-24.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1518-1524
    • Clemmons, D.R.1    Moses, A.C.2    McKay, M.J.3    Sommer, A.4    Rosen, D.M.5    Ruckle, J.6
  • 278
    • 0842346700 scopus 로고    scopus 로고
    • Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and ??-adrenergic response in ventricular myocytes
    • Norby FL, Aberle NS, Kajstura J, Anversa P, Ren J. Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and ??-adrenergic response in ventricular myocytes. J Endocrinol. 2004;180:175-82.
    • (2004) J Endocrinol , vol.180 , pp. 175-182
    • Norby, F.L.1    Aberle, N.S.2    Kajstura, J.3    Anversa, P.4    Ren, J.5
  • 279
    • 0036785626 scopus 로고    scopus 로고
    • IGF-I attenuates diabetes-induced cardiac contractile dysfunction in ventricular myocytes
    • Norby FL, Wold LE, Duan J, Hintz KK, Ren J. IGF-I attenuates diabetes-induced cardiac contractile dysfunction in ventricular myocytes. Am J Physiol Endocrinol Metab. 2002;283:E658-66.
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , pp. E658-E666
    • Norby, F.L.1    Wold, L.E.2    Duan, J.3    Hintz, K.K.4    Ren, J.5
  • 280
    • 77950290799 scopus 로고    scopus 로고
    • Minireview: Posttranscriptional regulation of the insulin and insulin-like growth factor systems
    • Lee EK, Gorospe M: Minireview: Posttranscriptional regulation of the insulin and insulin-like growth factor systems. Endocrinology. 2010;151:1403-8.
    • (2010) Endocrinology , vol.151 , pp. 1403-1408
    • Lee, E.K.1    Gorospe, M.2
  • 281
    • 73449091835 scopus 로고    scopus 로고
    • Mecasermin (recombinant human insulin-like growth factor I)
    • Rosenbloom AL. Mecasermin (recombinant human insulin-like growth factor I). Adv Ther. 2009;26:40-54.
    • (2009) Adv Ther , vol.26 , pp. 40-54
    • Rosenbloom, A.L.1
  • 282
    • 84885101641 scopus 로고    scopus 로고
    • GH therapy and cancer risk in hypopituitarism: What we know from human studies
    • Pekic S, Popovic V. GH therapy and cancer risk in hypopituitarism: What we know from human studies. Eur J Endocrinol. 2013.
    • (2013) Eur J Endocrinol
    • Pekic, S.1    Popovic, V.2
  • 283
    • 0027504363 scopus 로고
    • Short-term effects of recombinant human insulin-like growth factor I on bone turnover in normal women
    • Ebeling PR, Jones JD, O'Fallon WM, Janes CH, Riggs BL. Short-term effects of recombinant human insulin-like growth factor I on bone turnover in normal women. J Clin Endocrinol Metab. 1993;77:1384-7.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1384-1387
    • Ebeling, P.R.1    Jones, J.D.2    O'Fallon, W.M.3    Janes, C.H.4    Riggs, B.L.5
  • 284
    • 69249122402 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor-1 treatment: ready for primetime
    • Bright GM, Mendoza JR, Rosenfeld RG. Recombinant human insulin-like growth factor-1 treatment: ready for primetime. Endocrinol Metabol Clin N Am. 2009;38:625-38.
    • (2009) Endocrinol Metabol Clin N Am , vol.38 , pp. 625-638
    • Bright, G.M.1    Mendoza, J.R.2    Rosenfeld, R.G.3
  • 285
  • 287
    • 17244381353 scopus 로고    scopus 로고
    • Exercise and circulating insulin-like growth factor I
    • Berg U, Bang P. Exercise and circulating insulin-like growth factor I. Horm Res. 2004;62(suppl 1):50-8.
    • (2004) Horm Res , vol.62 , pp. 50-58
    • Berg, U.1    Bang, P.2
  • 288
    • 0031029857 scopus 로고    scopus 로고
    • Net fluxes over working thigh of hormones, growth factors and biomarkers of bone metabolism during short lasting dynamic exercise
    • Brahm H, Piehl-Aulin K, Saltin B, Ljunghall S. Net fluxes over working thigh of hormones, growth factors and biomarkers of bone metabolism during short lasting dynamic exercise. Calcif Tissue Int. 1997;60:175-80.
    • (1997) Calcif Tissue Int , vol.60 , pp. 175-180
    • Brahm, H.1    Piehl-Aulin, K.2    Saltin, B.3    Ljunghall, S.4
  • 289
    • 0035426212 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy
    • Carro E, Trejo JL, Busiguina S, Torres-Aleman I. Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy. J Neurosci. 2001;21:5678-84.
    • (2001) J Neurosci , vol.21 , pp. 5678-5684
    • Carro, E.1    Trejo, J.L.2    Busiguina, S.3    Torres-Aleman, I.4
  • 291
    • 84955631491 scopus 로고    scopus 로고
    • Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline
    • Huffman DM, Farias Quipildor G, Mao K, Zhang X, Wan J, Apontes P, Cohen P, Barzilai N. Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline. Aging Cell. 2015.
    • (2015) Aging Cell
    • Huffman, D.M.1    Farias Quipildor, G.2    Mao, K.3    Zhang, X.4    Wan, J.5    Apontes, P.6    Cohen, P.7    Barzilai, N.8


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