What is the function of IGF-II in postnatal life? Answers from transgenic mouse models

Growth Hormone and IGF Research

Volumn 8, Issue 3, 1998, Pages 185-193

  Wolf, E ^a   Hoeflich, A ^a   Lahm, H ^a  

^a Gene Center   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; BODY GROWTH; CARBOHYDRATE METABOLISM; CARCINOGENESIS; CONTROLLED STUDY; EMBRYO DEVELOPMENT; GENE EXPRESSION; GROWTH REGULATION; LIPID METABOLISM; MOUSE; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; REVIEW; TRANSGENIC MOUSE;

EID: 0032453535     PISSN: 10966374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-6374(98)80110-X     Document Type: Review

References (76)

1. Rappolee DA Werb Z Spencer EM Endogenous insulin-like growth factor II mediates growth in preimplantation mouse embryos, Modern concepts of insulin-like growth factors 1991 Elsevier Science Publishing New York 3 8
2. Harvey MB Kaye PL IGF-2 stimulates growth and metabolism of early mouse embryos Mech Dev 38 1992 169 174
3. DeChiara TM Efstratiadis A Robertson EJ A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting Nature 345 1990 78 80
4. DeChiara TM Robertson EJ Efstratiadis A Parental imprinting of the mouse insulin-like growth factor II gene Cell 64 1991 849 859
5. Liu J-P Baker J Perkins AS Robertson EJ Efstratiadis A Mice carrying null mutations of the genes encoding insulin-like growth factor I ( Igf-1 ) and type 1 IGF receptor ( Igf1r ) Cell 75 1993 59 72
6. Baker J Liu J-P Robertson EJ Efstratiadis A Role of insulin-like growth factors in embryonic and postnatal growth Cell 75 1993 73 82
7. Louvi A Accili D Efstratiadis A Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development Dev Biol 189 1997 33 48
8. Wang ZQ Fung MR Barlow DP Wagner EF Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene Nature 372 1994 464 467
9. Lau MMH Stewart CEH Liu Z Bhatt H Rotwein P Stewart CL Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality Genes Dev 8 1994 2953 2963
10. Ludwig T Eggenschwiler J Fisher P D'Ercole AJ Davenport MI Efstratiadis A Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds Dev Biol 177 1996 517 535
11. Sun F-L Dean WL Kelsey G Allen ND Reik W Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome Nature 389 1997 809 815
12. Gluckman PD Ambler GR What is the function of circulating insulin-like growth factor-2 in postnatal life Mol Cell Endocrinol 92 1993 C1 C3
13. Sussenbach JS Holthuizen P Steenbergh PH Structure and expression of the human insulin-like growth factor genes Growth Reg 2 1992 1 9
14. Zapf J Walter H Froesch ER Radioimmunological determination of insulinlike growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia J Clin Invest 68 1981 1321 1330
15. Blum WF Ranke MB Bierich JR A specific radioimmunoassay for insulin-like growth factor II: the interference of IGF binding proteins can be blocked by excess IGF-1 Acta Endocrinol (Copenh) 118 1988 374 380
16. Bennett AE Wahner HW Riggs BL Hintz RL Insulin-like growth factors I and II: aging and bone density in women J Clin Endocrinol Metab 59 1984 701 704
17. Soares MB Ishii DN Efstratiadis A Developmental and tissuespecific expression of a family of transcripts related to rat insulin-like growth factor II mRNA Nucleic Acids Res 13 1985 1119 1134
18. Murphy LJ Bell GI Friesen HG Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat Endocrinology 120 1987 1279 1282
19. Rotwein P Burgess SK Milbrandt JD Krause JE Differential expression of insulin-like growth factor genes in rat central nervous system Proc Natl Acad Sci USA 85 1988 265 269
20. Wilson DM Thomas JA Hamm TE Wyche J Hintz RL Rosenfeld RG Transplantation of IGF-II secreting tumours into nude rodents Endocrinology 120 1987 1896 1901
21. Bautista CM Mohan S Baylink DJ Insulin-like growth factors I and II are present in the skeletal tissues of ten vertebrates Metabolism 39 1990 96 100
22. Ren-Qiu Q Ruelicke T Hassam S Haselbacher GK Schoenle EJ Systemic effects of insulin-like growth factor-II produced and released from Wilms tumour tissue Eur J Pediatr 152 1993 102 106
23. Schofield PN Engstrom W Schofield PN The Insulin-like Growth Factors: Structure and Biological Functions 1992 Oxford University Press Oxford, New York, Tokyo 240 257
24. Cariani E Dubois N Lasserre C Briand P Brechot C Insulin-like growth factor II (IGF-II) mRNA expression during hepatocarcinogenesis in transgenic mice J Hepathol 13 1991 220 226
25. Schirmacher P Held WA Yang D Chisari FV Rustum Y Rogler CE Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth Cancer Res 52 1993 2549 2556
26. [Abstract] Wanke R Wolf E Brem G Reexpression of the insulin-like growth factor-2 gene in hepatocellular carcinomas from growth hormone transgenic mice Path Res Pract 191 1995 190
27. Kuenen BC van Doorn J Slee PH Non-islet-cell tumour induced hypoglycoaemia: a case report and review of literature Neth J Med 48 1996 175 179
28. Koea JB Breier BH Shaw JHF Gluckman PD A possible role for IGF-II: evidence in sheep for in vivo regulation of IGF-I mediated protein anabolism Endocrinology 130 1992 2423 2425
29. Ward A Bates P Fisher R Richardson L Graham CF Disproportionate growth in mice with Igf-2 transgenes Proc Natl Acad Sci USA 91 1994 10365 10369
30. Rogler CE Yang D Rossetti L Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice J Biol Chem 269 1994 13779 13784
31. Wolf E Kramer R Blum WF Föll J Brem G Consequences of postnatally elevated insulin-like growth factor-II in transgenic mice: endocrine changes and effects on body and organ growth Endocrinology 135 1994 1877 1886
32. van Buul-Offers SC de Haan K Reijnen-Gresnigt MG Overexpression of human insulin-like growth factor-II in transgenic mice causes increased growth of the thymus J Endocrinol 144 1995 491 502
33. Bates P Fisher R Ward A Richardson L Hill DJ Graham CF Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II) Br J Cancer 72 1995 1189 1193
34. Conover CA Regulation and physiological role of insulin-like growth factor binding proteins Endocr J 43 Suppl 1996 S43 S48
35. Kelley KM Oh Y Gargosky SE Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics Int J Biochem Cell Biol 28 1996 619 637
36. Da Costa THM Williamson DH Ward A High plasma insulin-like growth factor-II and low lipid content in transgenic mice: measurements of lipid metabolism J Endocrinol 143 1994 433 439
37. Douglas RG Gluckman PD Ball K Breier BH Shaw JHF The effects of insulin-like growth factor (IGF) I, IGF-II, and insulin on glucose and protein metabolism in fasted lambs J Clin Invest 88 1991 614 622
38. Blackburn A Dressendörfer RA Blum WF Erhard M Brem G Strasburger CJ Wolf E Interactions of insulin-like growth factor-II (IGF-II) and growth hormone (GH) in vivo : circulating levels of IGF-I and IGF-binding proteins in transgenic mice Eur J Endocrinol 137 1997 701 708
39. van Buul-Offers SC Reijnen-Gresnigt MG Hoogerbrugge CM Bloemen RJ Kuper CF Van den Brande JL Recombinant insulin-like growth factor-II inhibits the growth-stimulating effect of growth hormone on the liver of Snell dwarf mice Endocrinology 135 1994 977 985
40. MacDonald RG A sinigle receptor binds both insulin-like growth factor II and mannose-6-phosphate Science 239 1988 1134 1137
41. Morgan DO Edman JC Standring DN Fried VA Smith MC Roth RA Rutter WJ Insulin-like growth factor II receptors as a multifunctional binding protein Nature 329 1987 301 307
42. Schmidt B Kiecke Siemsen C Waheed A Braulke T von Figura K Localization of the insulin-like growth factor II binding site to amino acids 1508–1566 in repeat 11 of the mannose 6-phosphate/insulin-like growth factor II receptor J Biol Chem 270 1995 14975 14982
43. Hasilik A Neufeld EF Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight J Biol Chem 255 1980 4937 4945
44. Dahms NM Lobel P Kornfeld S Mannose 6-phosphate receptors and lysosomal enzyme targeting J Biol Chem 264 1989 12115 12118
45. 125I-insulin-like growth factor II degradation by modulating the IGF-II receptor recycling process J Biol Chem 260 1985 9435 9442
46. Kiess W Thomas CL Greenstein LA Insulin-like growth factor-II (IGF-II) inhibits both the cellular uptake of beta-galactosidase and the binding of beta-galactosidase to purified IGF-II/mannose 6-phosphate receptor J Biol Chem 264 1989 4710 4714
47. Hoeflich A Wolf E Braulke T Does the overexpression of pro-insulin-like growth factor-II in transfected human embryonic kidney fibroblasts increase the secretion of lysosomal enzymes? Eur J Biochem 232 1995 172 178
48. De Leon DD Terry C Asmerom Y Nissley P Insulin-like growth factor II modulates the routing of cathepsin D in MCF-7 breast cancer cells Endocrinology 137 1996 1851 1859
49. Kooijman R van Buul Offers SC Scholtens LE Schuurman HJ Van den Brande LJ Zegers BJ T cell development in insulin-like growth factor-II transgenic mice J Immunol 154 1995 5736 5745
50. Wolf E Rapp K Blum WF Kolb H Brem G Skeletal growth of transgenic mice with elevated levels of circulating insulin-like growth factor-II Growth Reg 5 1995 177 184
51. Wolf E Jehle PM Weber MM Human insulin-like growth factor-I produced in the mammary glands of transgenic rabbits: yield, receptor binding, mitogenic activity, and effects on IGF-binding proteins Endocrinology 138 1997 307 313
52. Blackburn A Schmitt A Schmidt P Wanke R Hermanns W Brem G Wolf E Actions and interactions of growth hormone and insulin-like growth factor-II: body and organ growth of transgenic mice Transgenic Res 6 1997 213 222
53. Wolf E Wanke R Schenck E Hermanns W Brem G Effects of growth hormone overproduction on grip strength of transgenic mice Eur J Endocrinol 133 1995 735 740
54. Rossetti L Barzilai N Chen W Harris T Yang D Rogler CE Hepatic overexpression of insulin-like growth factor-II in adulthood increases basal and insulin-stimulated glucose disposal in conscious mice J Biol Chem 271 1996 203 208
55. Stümpel F Hartmann H Acute actions of insulin-like growth factor II on glucose metabolism in adult rats Diabetologia 35 1992 932 938
56. Spiegelman BM Flier JS Adipogenesis and obesity: rounding out the big picture Cell 87 1996 377 389
57. Lowell BB Flier JS Brown adipose tissue, beta 3-adrenergic receotors, and obesity Annu Rev Med 48 1997 307 316
58. Rechler MM Nissley SP Sporn MB Roberts AB Peptide Growth Factors and Their Receptors I: Handbook of Experimental Pharmacology 1990 Springer Berlin, New York 263 267
59. Schofield PN Insulin-like Growth Factors: Structure and Biological Function 1992 Oxford Univ. Press London
60. Stylianopoulou F Herbert J Soares MB Efstratiadis A Expression of the insulin-like growth factor II gene in the choroid plexus and the lepotomeninges of the adult rat central nervous system Proc Natl Acad Sci USA 85 1988 141 145
61. Drummond IA Madden SL Rohwer Nutter P Bell GI Sukhatme VP Rauscher FJ III Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1 Science 257 1992 674 678
62. Lahm H Amstad P Yilmaz A Fischer JR Givel JC Odartchenko N Sordat B Differential effect of interleukin-4 and transforming growth factor β1 on expression of protooncogenes and autocrine insulin-like growth factor II in colorectal carcinoma cells Biochem Biophys Res Commun 220 1996 334 340
63. Forejt J Gregorova S Genetic analysis of genomic imprinting: an Imprintor-1 gene controls of inactivation of the paternal copy of the mouse Tme locus Cell 70 1992 443 450
64. Drop SLS Brinkman A Kortleve DJ Spencer EM Modern Concepts of Insulin-like Growth Factors 1991 Elsevier Science Publishing Co New York 311 328
65. Lahm H Amstad P Wyniger J Yilmaz A Fischer JR Schreyer M Givel JC Blockade of the insulin-like growth-factor-I receptor inhibits growth of human colorectal cancer cells: evidence of a functional IGF-II-mediated autocrine loop Int J Cancer 58 1994 452 459
66. Macaulay VM Insulin-like growth factors and cancer Br J Cancer 65 1992 311 320
67. Daughaday WH The possible autocrine/paracrine and endocrine roles of insulin-like growth factors of human tumors Endocrinology 127 1990 1 4
68. Reeve AE Expression of insulin-like growth factor II transcripts in Wilm's tumour Nature 317 1985 258 260
69. Christofori G Naik P Hanahan D A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis Nature 369 1994 414 418
70. Casola S Ungaro P Pedone PV Loss of heterozygosity of imprinted genes in SV40 t/T antigen-induced hepatocellular carcinomas Oncogene 11 1995 711 721
71. Mathews LS Hammer RE Behringer RR D'Ercole AJ Bell GI Brinster RL Palmiter RD Growth enhancement of transgenic mice expressing human insulin-like growth factor I Endocrinology 123 1988 2827 2833
72. Quaife CJ Mathews LS Pinkert CA Hammer RE Brinster RL Palmiter RD Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice Endocrinology 124 1989 40 48
73. Carson MJ Behringer RR Brinster RL McMorris FA Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice Neuron 10 1993 729 740
74. Hasegawa R Tiwawech D Hirose M Takaba K Hoshiya T Shirai T Ito N Suppression of diethylnitrosamine-initiated preneoplastic foci development in the rat liver by combined administration of four antioxidants at low doses Jpn J Cancer Res 83 1992 431 437
75. Hacker HJ Mtiro H Bannasch P Vesselinovitch SD Histochemical profile of mouse hepatocellular adenomas and carcinomas induced by a single dose of diethylnitrosamine Cancer Res 51 1991 1952 1958
76. Wise TL Pravtcheva DD Perinatal lethality in H19 enhancers- Igf2 transgenic mice Mol Reprod Dev 48 1997 194 207