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Volumn 276, Issue 3 39-3, 1999, Pages

Regulation of IGF binding protein-1 in Hep G2 cells by cytokines and reactive oxygen species

Author keywords

Free radicals; Insulin like growth factor; Interleukins 1 and 6; Liver; Nitric oxide; Nuclear factor B; Tumor necrosis factor

Indexed keywords

ICOSANOID; INTERLEUKIN 1; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 0032955687     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.3.g719     Document Type: Article
Times cited : (85)

References (49)
  • 1
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κΒB - A pivotal transcription factor in chronic inflammatory diseases
    • Barnes, H., and M. Karin. Nuclear factor-κΒB - a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336: 1066-1071, 1997.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1066-1071
    • Barnes, H.1    Karin, M.2
  • 2
    • 0025330755 scopus 로고
    • Superoxide anion generation in the liver during the early stage of endotoxemia in rats
    • Bautista, A. P., K. Meszaros, J. Bojta, and J. J. Spitzer. Superoxide anion generation in the liver during the early stage of endotoxemia in rats. J. Leukoc. Biol. 48: 123-128, 1990.
    • (1990) J. Leukoc. Biol. , vol.48 , pp. 123-128
    • Bautista, A.P.1    Meszaros, K.2    Bojta, J.3    Spitzer, J.J.4
  • 3
    • 0025667685 scopus 로고
    • Superoxide anion generation by in situ perfused rat liver: Effect of in vivo endotoxin
    • Gastrointest. Liver Physiol. 22
    • Bautista, A. P., and J. J. Spitzer. Superoxide anion generation by in situ perfused rat liver: effect of in vivo endotoxin. Am. J. Physiol. 259 (Gastrointest. Liver Physiol. 22): G907-G912, 1990.
    • (1990) Am. J. Physiol. , vol.259
    • Bautista, A.P.1    Spitzer, J.J.2
  • 4
    • 0028941256 scopus 로고
    • Effect of insulin on the alterations of growth hormone-IGF axis in children with new onset insulin dependent diabetes mellitus
    • Bereket, A., C. H. Lang, S. L. Blethen, M. C. Gelato, J. Fan, R. A. Frost, and T. A. Wilson. Effect of insulin on the alterations of growth hormone-IGF axis in children with new onset insulin dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 80: 1312-1317, 1995.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 1312-1317
    • Bereket, A.1    Lang, C.H.2    Blethen, S.L.3    Gelato, M.C.4    Fan, J.5    Frost, R.A.6    Wilson, T.A.7
  • 5
    • 0032549174 scopus 로고    scopus 로고
    • IκΒα degradation and nuclear factor-κΒ DNA binding are insufficient for interleukin-1β and tumor necrosis factor-α-induced κΒ-dependent transcription. Requirement for an additional activation pathway
    • Bergmann, M., L. Hart, M. Lindsay, P. J. Barnes, and R. Newton. IκΒα degradation and nuclear factor-κΒ DNA binding are insufficient for interleukin-1β and tumor necrosis factor-α-induced κΒ-dependent transcription. Requirement for an additional activation pathway. J. Biol. Chem. 273: 6607-6610, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6607-6610
    • Bergmann, M.1    Hart, L.2    Lindsay, M.3    Barnes, P.J.4    Newton, R.5
  • 6
    • 0032513053 scopus 로고    scopus 로고
    • Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence
    • Cichy, S. B., S. Uddin, A. Danilkovich, S. Guo, A. Klippel, and T. G. Unterman. Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence. J. Biol. Chem. 273: 6482-6487, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6482-6487
    • Cichy, S.B.1    Uddin, S.2    Danilkovich, A.3    Guo, S.4    Klippel, A.5    Unterman, T.G.6
  • 7
    • 0028846062 scopus 로고
    • Transcriptional repression of insulin-like growth factor I by glucocorticoids in rat bone cells
    • Delany, A. M, and E. Canalis. Transcriptional repression of insulin-like growth factor I by glucocorticoids in rat bone cells. Endocrinology 136: 4776-4781, 1995.
    • (1995) Endocrinology , vol.136 , pp. 4776-4781
    • Delany, A.M.1    Canalis, E.2
  • 8
    • 0025951812 scopus 로고
    • The complex pattern of cytokines in sepsis. Association between prostaglandins, cachectin, and interleukins
    • Ertel, W., M. H. Morrison, P. Wang, Z. F. Ba, A. Ayala, and I. H. Chaudry. The complex pattern of cytokines in sepsis. Association between prostaglandins, cachectin, and interleukins. Ann. Surg. 214: 141-148, 1991.
    • (1991) Ann. Surg. , vol.214 , pp. 141-148
    • Ertel, W.1    Morrison, M.H.2    Wang, P.3    Ba, Z.F.4    Ayala, A.5    Chaudry, I.H.6
  • 9
    • 0028789723 scopus 로고
    • Regulation of insulin-like growth factor I content and IGF-binding proteins by tumor necrosis factor
    • Regulatory Integrative Comp. Physiol. 38
    • Fan, J., G. J. Bagby, M. C. Gelato, and C. H. Lang. Regulation of insulin-like growth factor I content and IGF-binding proteins by tumor necrosis factor. Am. J. Physiol. 269 (Regulatory Integrative Comp. Physiol. 38): R1204-R1212, 1995.
    • (1995) Am. J. Physiol. , vol.269
    • Fan, J.1    Bagby, G.J.2    Gelato, M.C.3    Lang, C.H.4
  • 11
    • 0029340530 scopus 로고
    • Modulation of inflammation-induced changes in insulin-like growth factor (IGF)-I and IGF binding protein-1 by anti-TNF antibody
    • Fan, J., Y. H. Li, G. J. Bagby, and C. H. Lang. Modulation of inflammation-induced changes in insulin-like growth factor (IGF)-I and IGF binding protein-1 by anti-TNF antibody. Shock 4: 21-26, 1995.
    • (1995) Shock , vol.4 , pp. 21-26
    • Fan, J.1    Li, Y.H.2    Bagby, G.J.3    Lang, C.H.4
  • 12
    • 0028202862 scopus 로고
    • Differential tissue regulation of insulin-like growth factor I content and binding proteins after endotoxin
    • Fan, J., P. E. Molina, M. C. Gelato, and C. H. Lang. Differential tissue regulation of insulin-like growth factor I content and binding proteins after endotoxin. Endocrinology 134: 1685-1692, 1994.
    • (1994) Endocrinology , vol.134 , pp. 1685-1692
    • Fan, J.1    Molina, P.E.2    Gelato, M.C.3    Lang, C.H.4
  • 13
    • 0030004837 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor (IGF)-I mRNA and peptide, and IGF binding proteins by interleukin-1
    • Regulatory Integrative Comp. Physiol. 39
    • Fan, J., M. M. Wojnar, M. Theodorakis, and C. H. Lang. Regulation of insulin-like growth factor (IGF)-I mRNA and peptide, and IGF binding proteins by interleukin-1. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R621-R629, 1996.
    • (1996) Am. J. Physiol. , vol.270
    • Fan, J.1    Wojnar, M.M.2    Theodorakis, M.3    Lang, C.H.4
  • 15
    • 0028004814 scopus 로고
    • Temporal cascade of plasma level surges in ACTH, corticosterone, and cytokines in endotoxin-challenged rats
    • Regulatory Integrative Comp. Physiol. 36
    • Givalois, L., J. Dornand, M. Mekaouche, M. D. Solier, A. F. Bristow, G. Ixart, P. Siaud, I. Assenmacher, and G. Barbanel. Temporal cascade of plasma level surges in ACTH, corticosterone, and cytokines in endotoxin-challenged rats. Am. J. Physiol. 267 (Regulatory Integrative Comp. Physiol. 36): R164-R170, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Givalois, L.1    Dornand, J.2    Mekaouche, M.3    Solier, M.D.4    Bristow, A.F.5    Ixart, G.6    Siaud, P.7    Assenmacher, I.8    Barbanel, G.9
  • 17
    • 0031050763 scopus 로고    scopus 로고
    • Endotoxin-induced upregulation of type I interleukin-1 receptor mRNA expression hepatocytes of mice: Role of cytokines
    • Ito, A., T. Takii, T. Soji, and K. Onozaki. Endotoxin-induced upregulation of type I interleukin-1 receptor mRNA expression hepatocytes of mice: role of cytokines. J. Interferon Cytokine Res. 17: 55-61, 1997.
    • (1997) J. Interferon Cytokine Res. , vol.17 , pp. 55-61
    • Ito, A.1    Takii, T.2    Soji, T.3    Onozaki, K.4
  • 18
    • 1842329163 scopus 로고    scopus 로고
    • Mechanisms of neutrophil-induced parenchymal cell injury
    • Jaeschke, H., and C. W. Smith. Mechanisms of neutrophil-induced parenchymal cell injury. J. Leukoc. Biol. 61: 647-653, 1997.
    • (1997) J. Leukoc. Biol. , vol.61 , pp. 647-653
    • Jaeschke, H.1    Smith, C.W.2
  • 20
    • 0031031148 scopus 로고    scopus 로고
    • Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-α-induced apoptosis by inducing heat shock protein 70 expression
    • Kim, Y.-M., M. E. de Vera, S. C. Watkins, and T. R. Billiar. Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-α-induced apoptosis by inducing heat shock protein 70 expression. J. Biol. Chem. 272: 1402-1411, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1402-1411
    • Kim, Y.-M.1    De Vera, M.E.2    Watkins, S.C.3    Billiar, T.R.4
  • 21
    • 16044372220 scopus 로고    scopus 로고
    • Increased nitric oxide synthase activity as a cause of mitochondrial dysfunction in rat hepatocytes: Roles for tumor necrosis factor α
    • Kurose, I., S. Miura, H. Higuchi, N. Watanabe, Y. Kamegaya, M. Takaishi, K. Tomita, D. Fukumura, S. Kato, and H. Ishii. Increased nitric oxide synthase activity as a cause of mitochondrial dysfunction in rat hepatocytes: roles for tumor necrosis factor α. Hepatology 24: 1185-1192, 1996.
    • (1996) Hepatology , vol.24 , pp. 1185-1192
    • Kurose, I.1    Miura, S.2    Higuchi, H.3    Watanabe, N.4    Kamegaya, Y.5    Takaishi, M.6    Tomita, K.7    Fukumura, D.8    Kato, S.9    Ishii, H.10
  • 22
    • 0029984415 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist attenuates sepsis-induced alterations in the insulin-like growth factor system and protein synthesis
    • Endocrinol. Metab. 33
    • Lang, C. H., J. Fan, R. Cooney, and T. C. Vary. Interleukin-1 receptor antagonist attenuates sepsis-induced alterations in the insulin-like growth factor system and protein synthesis. Am. J. Physiol. 270 (Endocrinol. Metab. 33): E430-E437, 1996.
    • (1996) Am. J. Physiol. , vol.270
    • Lang, C.H.1    Fan, J.2    Cooney, R.3    Vary, T.C.4
  • 23
    • 0026767518 scopus 로고
    • Role of protein kinase C in regulation of insulin-like growth factor binding protein-1 production by HepG2 cells
    • Lee, P. D. K., L. S. Abdel-Maguid, and M. B. Snuggs. Role of protein kinase C in regulation of insulin-like growth factor binding protein-1 production by HepG2 cells. J. Clin. Endocrinol. Metab. 75: 459-464, 1992.
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 459-464
    • Lee, P.D.K.1    Abdel-Maguid, L.S.2    Snuggs, M.B.3
  • 24
    • 0027320012 scopus 로고
    • Regulation and function of insulin-like growth factor-binding protein-1
    • Lee, P. D. K., C. Conover, and D. R. Powell. Regulation and function of insulin-like growth factor-binding protein-1. Proc. Soc. Exp. Biol. Med. 204: 4-29, 1993.
    • (1993) Proc. Soc. Exp. Biol. Med. , vol.204 , pp. 4-29
    • Lee, P.D.K.1    Conover, C.2    Powell, D.R.3
  • 25
    • 0027417005 scopus 로고
    • Insulin-like growth factor binding protein-1 response to insulin during suppression of endogenous insulin secretion
    • Lee, P. D. K., M. D. Jensen, G. D. Divertie, V. J. Heiling, H. H. Katz, and C. A. Conover. Insulin-like growth factor binding protein-1 response to insulin during suppression of endogenous insulin secretion. Metabolism 42: 409-414, 1993.
    • (1993) Metabolism , vol.42 , pp. 409-414
    • Lee, P.D.K.1    Jensen, M.D.2    Divertie, G.D.3    Heiling, V.J.4    Katz, H.H.5    Conover, C.A.6
  • 26
    • 0030026550 scopus 로고    scopus 로고
    • Interaction of insulin, glucocorticoids, and protein kinase C in the regulation of insulin-like growth factor-binding protein-1 production by H4IIE rat hepatoma cells
    • Lewitt, M. S., H. Saunders, and R. C. Baxter. Interaction of insulin, glucocorticoids, and protein kinase C in the regulation of insulin-like growth factor-binding protein-1 production by H4IIE rat hepatoma cells. J. Cell. Physiol. 166: 121-129, 1996.
    • (1996) J. Cell. Physiol. , vol.166 , pp. 121-129
    • Lewitt, M.S.1    Saunders, H.2    Baxter, R.C.3
  • 27
    • 0041959989 scopus 로고    scopus 로고
    • Role of glucocorticoids in mediating endotoxin-induced changes in IGF-I and IGF binding protein-1
    • Regulatory Integrative Comp. Physiol. 41
    • Li, Y. H., J. Fan, and C. H. Lang. Role of glucocorticoids in mediating endotoxin-induced changes in IGF-I and IGF binding protein-1. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R1970-R1977, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Li, Y.H.1    Fan, J.2    Lang, C.H.3
  • 28
    • 0029006149 scopus 로고    scopus 로고
    • Inhibition of nuclear translocation of transcription factor NF-κΒ by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
    • Lin, Y. Z., S. Y. Yao, R. A. Veach, T. R. Torgerson, and J. Hawiger. Inhibition of nuclear translocation of transcription factor NF-κΒ by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem. 270: 14255-14258, 1997.
    • (1997) J. Biol. Chem. , vol.270 , pp. 14255-14258
    • Lin, Y.Z.1    Yao, S.Y.2    Veach, R.A.3    Torgerson, T.R.4    Hawiger, J.5
  • 29
    • 0030026355 scopus 로고    scopus 로고
    • Regulation of GLUT 4 gene expression by arachidonic acid
    • Long, S. D., and P. H. Pekala. Regulation of GLUT 4 gene expression by arachidonic acid. J. Biol. Chem. 271: 1138-1144, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1138-1144
    • Long, S.D.1    Pekala, P.H.2
  • 30
    • 0025765623 scopus 로고
    • Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines
    • Mackiewicz, A., T. Speroff, M. K. Ganapathi, and I. Kushner. Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines. J. Immunol. 146: 3032-3037, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 3032-3037
    • Mackiewicz, A.1    Speroff, T.2    Ganapathi, M.K.3    Kushner, I.4
  • 31
    • 0000459280 scopus 로고
    • The insulin-like growth factor binding proteins: Structure and biological functions
    • edited by P. N. Schofield. New York: Oxford University Press
    • McCusker, R. H., and D. R. Clemmons. The insulin-like growth factor binding proteins: structure and biological functions. In: The Insulin-Like Growth Factors: Structure and Biological Functions, edited by P. N. Schofield. New York: Oxford University Press, 1992, p. 110-150.
    • (1992) The Insulin-like Growth Factors: Structure and Biological Functions , pp. 110-150
    • McCusker, R.H.1    Clemmons, D.R.2
  • 32
  • 33
    • 0001255456 scopus 로고    scopus 로고
    • Quercetin inhibits hydrogen peroxide-induced NF-κΒ DNA binding activity and DNA damage in HepG2 cells
    • Musonda, C. A., and J. K. Chipman. Quercetin inhibits hydrogen peroxide-induced NF-κΒ DNA binding activity and DNA damage in HepG2 cells. Carcinogenesis 19: 1583-1589, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 1583-1589
    • Musonda, C.A.1    Chipman, J.K.2
  • 34
    • 0030051916 scopus 로고    scopus 로고
    • Superinduction of NF-κΒ by actinomycin D and cycloheximide in epithelial cells
    • Newton, R., I. M. Adcock, and P. J. Barnes. Superinduction of NF-κΒ by actinomycin D and cycloheximide in epithelial cells. Biochem. Biophys. Res. Commun. 218: 518-523, 1996.
    • (1996) Biochem. Biophys. Res. Commun. , vol.218 , pp. 518-523
    • Newton, R.1    Adcock, I.M.2    Barnes, P.J.3
  • 35
    • 0027282079 scopus 로고
    • Cycloheximide stabilizes insulin-like growth factor-binding protein-1 (IGFBP-1) mRNA and inhibits IGFBP-1 transcription in H4-II-E rat hepatoma cells
    • Ooi, G. T., D. R. Brown, D. S. Suh, L. Y. Tseng, and M. M. Rechler. Cycloheximide stabilizes insulin-like growth factor-binding protein-1 (IGFBP-1) mRNA and inhibits IGFBP-1 transcription in H4-II-E rat hepatoma cells. J. Biol. Chem. 268: 16664-16672, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16664-16672
    • Ooi, G.T.1    Brown, D.R.2    Suh, D.S.3    Tseng, L.Y.4    Rechler, M.M.5
  • 36
    • 0025149517 scopus 로고
    • Dexamethasone stimulates transcription of the insulin-like growth factor-binding protein-1 gene in H4-II-E rat hepatoma cells
    • Orlowski, C. C., G. T. Ooi, and M. M. Rechler. Dexamethasone stimulates transcription of the insulin-like growth factor-binding protein-1 gene in H4-II-E rat hepatoma cells. Mol. Endocrinol. 4: 1592-1599, 1990.
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1592-1599
    • Orlowski, C.C.1    Ooi, G.T.2    Rechler, M.M.3
  • 37
    • 0027770992 scopus 로고
    • Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein 1 gene transcription by hormones and provision of amino acids in rat hepatocytes
    • Pao, C.-I., P. K. Farmer, S. Begovic, B. C. Villafuerte, G. Wu, D. G. Robertson, and L. S. Phillips. Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein 1 gene transcription by hormones and provision of amino acids in rat hepatocytes. Mol. Endocrinol. 7: 1561-1568, 1993.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1561-1568
    • Pao, C.-I.1    Farmer, P.K.2    Begovic, S.3    Villafuerte, B.C.4    Wu, G.5    Robertson, D.G.6    Phillips, L.S.7
  • 38
    • 0026052697 scopus 로고
    • Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1
    • Powell, D. R., A. Suwanichkul, M. L. Cubbage, L. A. DePaolis, M. B. Snuggs, and P. D. K. Lee. Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1. J. Biol. Chem. 266: 18868-18876, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18868-18876
    • Powell, D.R.1    Suwanichkul, A.2    Cubbage, M.L.3    Depaolis, L.A.4    Snuggs, M.B.5    Lee, P.D.K.6
  • 39
    • 0030695187 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase in interleukin-1 signaling
    • Reddy, S. A. G., J. H. Huang, and W. S. L. Liao. Phosphatidylinositol 3-kinase in interleukin-1 signaling. J. Biol. Chem. 272: 29167-29173, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29167-29173
    • Reddy, S.A.G.1    Huang, J.H.2    Liao, W.S.L.3
  • 40
    • 0038807982 scopus 로고    scopus 로고
    • Alterations of antioxidant enzyme expression response to hydrogen peroxide
    • Rohrdanz, E., and R. Kahl. Alterations of antioxidant enzyme expression response to hydrogen peroxide. Free Radic. Biol. Med. 24: 27-38, 1998.
    • (1998) Free Radic. Biol. Med. , vol.24 , pp. 27-38
    • Rohrdanz, E.1    Kahl, R.2
  • 42
    • 0029872210 scopus 로고    scopus 로고
    • Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary culture. Involvement of reactive oxygen intermediates
    • Sanchez, A., A. M. Alvarez, M. Benito, and I. Fabregat. Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary culture. Involvement of reactive oxygen intermediates. J. Biol. Chem. 271: 7416-7422, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7416-7422
    • Sanchez, A.1    Alvarez, A.M.2    Benito, M.3    Fabregat, I.4
  • 44
    • 0027199772 scopus 로고
    • Identification of an insulin-responsive element in the promoter of the human gene for insulin-like growth binding protein-1
    • Suwanickul, A., S. L. Morris, and D. R. Powell. Identification of an insulin-responsive element in the promoter of the human gene for insulin-like growth binding protein-1. J. Biol. Chem. 268: 17063-17068, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 17063-17068
    • Suwanickul, A.1    Morris, S.L.2    Powell, D.R.3
  • 45
  • 46
    • 1842298691 scopus 로고    scopus 로고
    • Thiol modulation inhibits the interleukin (IL)-1 mediated activation of an IL-1 receptor-associated protein kinase and NF-κΒ
    • Tewes, F., G. F. Bol, and R. Brigelius-Flohe. Thiol modulation inhibits the interleukin (IL)-1 mediated activation of an IL-1 receptor-associated protein kinase and NF-κΒ. Eur. J. Immunol. 27: 3015-3021, 1998.
    • (1998) Eur. J. Immunol. , vol.27 , pp. 3015-3021
    • Tewes, F.1    Bol, G.F.2    Brigelius-Flohe, R.3
  • 47
    • 0025802831 scopus 로고
    • Endotoxin-induced cytokine gene expression in vivo. III. IL-6 mRNA and serum protein expression and the in vivo hematologic effects of IL-6
    • Ulich, T. R., K. Guo, D. Remick, J. del Castillo, and S. Yin. Endotoxin-induced cytokine gene expression in vivo. III. IL-6 mRNA and serum protein expression and the in vivo hematologic effects of IL-6. J. Immunol. 146: 2316-2323, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 2316-2323
    • Ulich, T.R.1    Guo, K.2    Remick, D.3    Del Castillo, J.4    Yin, S.5
  • 48
    • 0025883504 scopus 로고
    • Multihormonal regulation of insulin-like growth factor binding protein-1 in rat H4EII hepatoma cells: The dominant role of insulin
    • Unterman, T. G., D. T. Oehler, L. J. Murphy, and R. G. Lacson. Multihormonal regulation of insulin-like growth factor binding protein-1 in rat H4EII hepatoma cells: the dominant role of insulin. Endocrinology 128: 2693-2701, 1991.
    • (1991) Endocrinology , vol.128 , pp. 2693-2701
    • Unterman, T.G.1    Oehler, D.T.2    Murphy, L.J.3    Lacson, R.G.4
  • 49
    • 0028930465 scopus 로고
    • Chronic alcohol administration stimulates nitric oxide formation in the rat liver with or without pretreatment by lipopolysaccharide
    • Wang, J. F., S. S. Greenberg, and J. J. Spitzer. Chronic alcohol administration stimulates nitric oxide formation in the rat liver with or without pretreatment by lipopolysaccharide. Alcohol. Clin. Exp. Res. 19: 387-393, 1995.
    • (1995) Alcohol. Clin. Exp. Res. , vol.19 , pp. 387-393
    • Wang, J.F.1    Greenberg, S.S.2    Spitzer, J.J.3


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