-
1
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
doi:10.1038/ng.520. PubMed: 20081858
-
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N et al. (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 42: 105-116. doi:10.1038/ng.520. PubMed: 20081858.
-
(2010)
Nat Genet
, vol.42
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
Saxena, R.4
Soranzo, N.5
-
2
-
-
84865693929
-
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
-
doi:10.1038/ng.2385. PubMed: 22885924
-
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME et al. (2012) Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet;44: 991-1005. doi:10.1038/ng.2385. PubMed: 22885924.
-
(2012)
Nat Genet
, vol.44
, pp. 991-1005
-
-
Scott, R.A.1
Lagou, V.2
Welch, R.P.3
Wheeler, E.4
Montasser, M.E.5
-
3
-
-
0035033682
-
Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity
-
Yakar S, Liu JL, Fernandez AM, Wu Y, Schally AV et al. (2001) Liver-specific IGF-1 gene deletion leads to muscle insulin insensitivity. Diabetes; 50: 1110-1118. doi:10.2337/diabetes.50.5.1110. PubMed: 11334415. (Pubitemid 32374542)
-
(2001)
Diabetes
, vol.50
, Issue.5
, pp. 1110-1118
-
-
Yakar, S.1
Liu, J.-L.2
Fernandez, A.M.3
Wu, Y.4
Schally, A.V.5
Frystyk, J.6
Chernausek, S.D.7
Mejia, W.8
Le, R.D.9
-
4
-
-
70350594050
-
Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects
-
doi: 10.1016/j.numecd.2008.12.011. PubMed: 19346116
-
Succurro E, Andreozzi F, Marini MA, Lauro R, Hribal ML et al. (2009) Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects. Nutr Metab Cardiovasc Dis 19: 713-719. doi: 10.1016/j.numecd.2008.12.011. PubMed: 19346116.
-
(2009)
Nutr Metab Cardiovasc Dis
, vol.19
, pp. 713-719
-
-
Succurro, E.1
Andreozzi, F.2
Marini, M.A.3
Lauro, R.4
Hribal, M.L.5
-
5
-
-
19944426300
-
Plasma concentration of insulin-like growth factor-I is independently associated with insulin sensitivity in subjects with different degree of glucose tolerance
-
doi:10.2337/diacare. 28.1.132. PubMed: 15616244
-
Sesti G, Sciacqua A, Cardellini M, Marini MA, Maio R et al. (2005) Plasma concentration of insulin-like growth factor-I is independently associated with insulin sensitivity in subjects with different degree of glucose tolerance. Diabetes Care 28: 132-137. doi:10.2337/diacare. 28.1.132. PubMed: 15616244.
-
(2005)
Diabetes Care
, vol.28
, pp. 132-137
-
-
Sesti, G.1
Sciacqua, A.2
Cardellini, M.3
Marini, M.A.4
Maio, R.5
-
6
-
-
0037129721
-
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: A prospective observational study
-
DOI 10.1016/S0140-6736(02)08655-5
-
Sandhu MS, Heald AH, Gibson JM, Cruickshank JK, Dunger DB et al. (2002) Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study. Lancet 359: 1740-1745. doi:10.1016/S0140-6736(02)08655-5. PubMed: 12049864. (Pubitemid 34607089)
-
(2002)
Lancet
, vol.359
, Issue.9319
, pp. 1740-1745
-
-
Sandhu, M.S.1
Heald, A.H.2
Gibson, J.M.3
Cruickshank, J.K.4
Dunger, D.B.5
Wareham, N.J.6
-
7
-
-
77951858557
-
Detailed physiologic characterization reveals diverse mechanisms for novel genetic loci regulating glucose and insulin metabolism in humans
-
doi:10.2337/db09-1568. PubMed: 20185807
-
Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V et al. (2010) Detailed physiologic characterization reveals diverse mechanisms for novel genetic loci regulating glucose and insulin metabolism in humans. Diabetes 59: 1266-1275. doi:10.2337/db09-1568. PubMed: 20185807.
-
(2010)
Diabetes
, vol.59
, pp. 1266-1275
-
-
Ingelsson, E.1
Langenberg, C.2
Hivert, M.F.3
Prokopenko, I.4
Lyssenko, V.5
-
8
-
-
84877754351
-
Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance
-
doi:10.1007/s00125-013-2880-6. PubMed: 23494448
-
Goodarzi MO, Guo X, Cui J, Jones MR, Haritunians T et al. (2013) Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance. Diabetologia 56: 1282-1290. doi:10.1007/s00125-013-2880-6. PubMed: 23494448.
-
(2013)
Diabetologia
, vol.56
, pp. 1282-1290
-
-
Goodarzi, M.O.1
Guo, X.2
Cui, J.3
Jones, M.R.4
Haritunians, T.5
-
9
-
-
79960804236
-
Fasting insulin reflects heterogeneous physiological processes: Role of insulin clearance
-
doi:10.1152/ajpendo.00013.2011. PubMed: 21632466
-
Goodarzi MO, Cui J, Chen YD, Hsueh WA, Guo X et al. (2011) Fasting insulin reflects heterogeneous physiological processes: role of insulin clearance. Am J Physiol Endocrinol Metab 301: E402-E408. doi:10.1152/ajpendo. 00013.2011. PubMed: 21632466.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.301
-
-
Goodarzi, M.O.1
Cui, J.2
Chen, Y.D.3
Hsueh, W.A.4
Guo, X.5
-
10
-
-
0037622751
-
972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients
-
DOI 10.1210/jc.2002-021716
-
Marini MA, Frontoni S, Mineo D, Bracaglia D, Cardellini M et al. (2003) The Arg972variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients. J Clin Endocrinol Metab 88: 3368-3371. doi:10.1210/jc.2002-021716. PubMed: 12843189. (Pubitemid 36877518)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.7
, pp. 3368-3371
-
-
Marini, M.A.1
Frontoni, S.2
Mineo, D.3
Bracaglia, D.4
Cardellini, M.5
De Nicolais, P.6
Baroni, A.7
D'Alfonso, R.8
Perna, M.9
Lauro, D.10
Federici, M.11
Gambardella, S.12
Lauro, R.13
Sesti, G.14
-
11
-
-
40749087319
-
A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: Results from the EUGENE2 study
-
PubMed: 18039816
-
Staiger H, Stancáková A, Zilinskaite J, Vänttinen M, Hansen T et al. (2008) A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study. Diabetes 57: 514-517. PubMed: 18039816.
-
(2008)
Diabetes
, vol.57
, pp. 514-517
-
-
Staiger, H.1
Stancáková, A.2
Zilinskaite, J.3
Vänttinen, M.4
Hansen, T.5
-
12
-
-
33745304040
-
Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in Caucasian Italian subjects
-
DOI 10.2337/db06-0047
-
Scarpelli D, Cardellini M, Andreozzi F, Laratta E, Hribal ML et al. (2006) Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes mellitus in Caucasian Italian subjects. Diabetes 55: 1529-1533. doi:10.2337/db06-0047. PubMed: 16644716. (Pubitemid 44195398)
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1529-1533
-
-
Scarpelli, D.1
Cardellini, M.2
Andreozzi, F.3
Laratta, E.4
Hribal, M.L.5
Marini, M.A.6
Tassi, V.7
Lauro, R.8
Perticone, F.9
Sesti, G.10
-
14
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
DOI 10.1007/BF00280883
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419. doi:10.1007/BF00280883. PubMed: 3899825. (Pubitemid 15018832)
-
(1985)
Diabetologia
, vol.28
, Issue.7
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
-
15
-
-
0030032795
-
Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes
-
Moses AC, Young SC, Morrow LA, O'Brien M, Clemmons DR (1996) Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes. Diabetes 45: 91-100. doi:10.2337/diab.45. 3.S91. PubMed: 8522066. (Pubitemid 26010429)
-
(1996)
Diabetes
, vol.45
, Issue.1
, pp. 91-100
-
-
Moses, A.C.1
Young, S.C.J.2
Morrow, L.A.3
O'Brien, M.4
Clemmons, D.R.5
-
16
-
-
0030996802
-
Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues
-
DOI 10.1016/S0303-7207(97)04050-1, PII S0303720797040501
-
Federici M, Porzio O, Zucaro L, Fusco A, Borboni P et al. (1997) Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues. Mol Cell Endocrinol 129: 121-126. doi:10.1016/S0303-7207(97)04050-1. PubMed: 9202395. (Pubitemid 27281527)
-
(1997)
Molecular and Cellular Endocrinology
, vol.129
, Issue.2
, pp. 121-126
-
-
Federici, M.1
Porzio, O.2
Zucaro, L.3
Fusco, A.4
Borboni, P.5
Lauro, D.6
Sesti, G.7
-
17
-
-
0030453978
-
Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of non-insulin-dependent diabetes mellitus subjects
-
doi:10.1172/JCI119117. PubMed: 8981937
-
Federici M, Zucaro L, Porzio O, Massoud R, Borboni P et al. (1996) Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of non-insulin-dependent diabetes mellitus subjects. J Clin Invest 98: 2887-2893. doi:10.1172/JCI119117. PubMed: 8981937.
-
(1996)
J Clin Invest
, vol.98
, pp. 2887-2893
-
-
Federici, M.1
Zucaro, L.2
Porzio, O.3
Massoud, R.4
Borboni, P.5
-
18
-
-
0031727326
-
Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vive insulin sensitivity
-
DOI 10.1210/jc.83.8.2911
-
Federici M, Porzio O, Lauro D, Borboni P, Giovannone B et al. (1998) Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity. J Clin Endocrinol Metab 83: 2911-2915. doi:10.1210/jc.83.8.2911. PubMed: 9709968. (Pubitemid 28493797)
-
(1998)
Journal of Clinical Endocrinology and Metabolism
, vol.83
, Issue.8
, pp. 2911-2915
-
-
Federici, M.1
Porzio, O.2
Lauro, D.3
Borboni, P.4
Giovannone, B.5
Zucaro, L.6
Hribal, M.L.7
Sesti, G.8
-
19
-
-
0031965286
-
Expression of insulin/IGF-I hybrid receptors is increased in skeletal muscle of patients with chronic primary hyperinsulinemia
-
Federici M, Lauro D, D'Adamo M, Giovannone B, Porzio O et al. (1998) Expression of insulin/IGF-I hybrid receptors is increased in skeletal muscle of patients with chronic primary hyperinsulinemia. Diabetes 47: 87-92. doi:10.2337/diabetes.47.1.87. PubMed: 9421379. (Pubitemid 28030812)
-
(1998)
Diabetes
, vol.47
, Issue.1
, pp. 87-92
-
-
Federici, M.1
Lauro, D.2
D'Adamo, M.3
Giovannone, B.4
Porzio, O.5
Mellozzi, M.6
Tamburrano, G.7
Sbraccia, P.8
Sesti, G.9
-
20
-
-
1542466784
-
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice
-
DOI 10.1172/JCI200417763
-
Yakar S, Setser J, Zhao H, Stannard B, Haluzik M et al. (2004) Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice. J Clin Invest 113: 96-105. doi:10.1172/JCI200417763. PubMed: 14702113. (Pubitemid 38541636)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.1
, pp. 96-105
-
-
Yakar, S.1
Setser, J.2
Zhao, H.3
Stannard, B.4
Haluzik, M.5
Glatt, V.6
Bouxsein, M.L.7
Kopchick, J.J.8
LeRoith, D.9
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