Randomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the rat

Arthritis Research and Therapy

Volumn 18, Issue 1, 2016, Pages

  TenBroek, Erica M ^a   Yunker, Laurie ^a   Nies, Mae Foster ^a   Bendele, Alison M ^b  

^a MEDTRONIC INC   (United States)

^b BolderPATH   (United States)

Author keywords

Arthritis; Bone remodeling; Degeneration; Meniscal; Monoiodoacetic; NF B; Osteoarthritis; Pain; RANKL; Therapeutics

Indexed keywords

(5 PHENYL 2 UREIDO)THIOPHENE 3 CARBOXAMIDE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (2 AMINOETHYLAMINO) 1,8 DIMETHYLIMIDAZO[1,2 A]QUINOXALINE; ALENDRONIC ACID; ANTIRHEUMATIC AGENT; ASCOMYCIN; CLONIDINE; COLLAGENASE 3; CURCUMIN; DIACEREIN; EPIGALLOCATECHIN GALLATE; FLUOCINOLONE; I KAPPA B KINASE INHIBITOR; ILOMASTAT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MELOXICAM; MORPHINE; N (3,5 BIS TRIFLUOROMETHYL PHENYL) 5 CHLORO 2 HYDROXY BENZAMIDE; OSTEOCLAST DIFFERENTIATION FACTOR; PIMECROLIMUS; RESVERATROL; RHEIN; SULINDAC; TACROLIMUS; TRANILAST; TRIAMCINOLONE; TRIAMCINOLONE ACETONIDE; TRIAMCINOLONE HEXACETONIDE; UNCLASSIFIED DRUG; WITHAFERIN A; AUTACOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; DRUG SCREENING; ENZYME ACTIVITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KNEE LIGAMENT INJURY; KNEE MENISCUS RUPTURE; MALE; MECHANICAL HYPERALGESIA; NONHUMAN; OSTEOARTHRITIS; OSTEOCLASTOGENESIS; RAT; TOXICITY TESTING; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTICULAR CARTILAGE; CELL LINE; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECTS; HELA CELL LINE; LEWIS RAT; METABOLISM; MOUSE; PAIN; PATHOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC); SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; ANTIRHEUMATIC AGENTS; CARTILAGE, ARTICULAR; CELL LINE; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; INFLAMMATION MEDIATORS; MALE; MICE; OSTEOARTHRITIS; PAIN; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RATS; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME;

EID: 84954554001     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-016-0921-5     Document Type: Article

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